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  1. Book ; Thesis: Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies

    Gorgulho, João

    2022  

    Author's details vorgelegt von João Silveira Botelho de Sousa Gorgulho
    Language English
    Size Seite 1189-1198, Diagramme
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2022
    Note Die Dissertation besteht aus einem Aufsatz, der zuvor in der Zeitschrift "Int. J. Cancer" (2021; 1-10) veröffentlicht wurde sowie ergänzendem Material; DOI: 10.1002/ijc.33610
    HBZ-ID HT021499709
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 D 19 order for loan Magazin

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  2. Book: Vestigios da lingua Arabica em Portugal /João de Sousa ; pref. de A. Farinha

    Sousa, João de

    1981  

    Language Portuguese
    Size XX, 160 S, 1 Kt
    Edition Ed. facsimile
    Publishing place Capa de Armando Alves: Graf. Maiaduero
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book ; Online: Boaventura de Sousa Santos

    Santos, Boaventura de Sousa / Meneses, Maria Paula / Nunes, João Arriscado

    Construyendo las Epistemologías del Sur Para un pensamiento alternativo de alternativas, Volumen I

    (Antologías del pensamiento social latinoamericano y caribeño)

    2019  

    Series title Antologías del pensamiento social latinoamericano y caribeño
    Keywords Western philosophy, from c 1900 ; Philosophy
    Language Spanish
    Size 1 Online-Ressource
    Publisher CLACSO
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030610896
    ISBN 9789877223637 ; 9877223635
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Boaventura de Sousa Santos

    Santos, Boaventura de Sousa / Meneses, Maria Paula / Nunes, João Arriscado

    Construyendo las Epistemologías del Sur Para un pensamiento alternativo de alternativas, Volumen II

    (Antologías del pensamiento social latinoamericano y caribeño)

    2019  

    Series title Antologías del pensamiento social latinoamericano y caribeño
    Keywords Western philosophy, from c 1900 ; Philosophy
    Language Spanish
    Size 1 Online-Ressource
    Publisher CLACSO
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030611073
    ISBN 9789877223644 ; 9877223643
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: An Unusual Coexistence: Right-Sided Colon Cancer and Intestinal Malrotation in an Adult.

    Vieira, Bruno / Ribeiro, Artur / Sousa, Paulo / Leal, Clara / Pinto-de-Sousa, João

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55461

    Abstract: Intestinal malrotation (IM), a rare congenital anomaly disrupting typical embryonic rotation around the superior mesenteric artery, is exceptionally uncommon in adults, with its link to colon cancer being even rarer. This article presents a case of ... ...

    Abstract Intestinal malrotation (IM), a rare congenital anomaly disrupting typical embryonic rotation around the superior mesenteric artery, is exceptionally uncommon in adults, with its link to colon cancer being even rarer. This article presents a case of colonic cancer in conjunction with IM in a 63-year-old male. Image studies and intraoperative findings show signs of IM. Open resection was performed due to concerns about vascular anomalies and abnormal lymphatic drainage. The case underscores the rarity of colon cancer in a malrotated gut, highlighting the necessity of preoperative identification for precise surgical planning and emphasizing the importance of careful dissection to prevent inadvertent vascular injury.
    Language English
    Publishing date 2024-03-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55461
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Routine Use of Neck Drains Following Thyroid Operations to Prevent Complications Is No Longer Advisable.

    Guidi, Gonçalo / Santos, Carlos / Pinto-de-Sousa, João

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54388

    Abstract: Background: The use of cervical drains to prevent cervical hematoma or seroma after thyroidectomy remains a controversial issue.: Objective: Identify clinical and surgical risk factors for hematoma or seroma and evaluate the usefulness of routine use ...

    Abstract Background: The use of cervical drains to prevent cervical hematoma or seroma after thyroidectomy remains a controversial issue.
    Objective: Identify clinical and surgical risk factors for hematoma or seroma and evaluate the usefulness of routine use of drains following thyroid surgery.
    Material and methods: The authors conducted a retrospective multicentric study related to consecutive patients submitted to thyroid surgery in seven Portuguese hospitals between January 2018 and December 2020 (n=945). The data collected included the following parameters: age and gender of the patients, anticoagulation or anti-aggregating therapy, histological diagnoses, type of surgery, the presence or absence of postoperative drains, thyroid weight, length of hospital stay, postoperative complications, and reinterventions. In this study, surgical complications evaluated were limited to the presence of hematoma or seroma. A total of 945 patients who underwent thyroid surgery were included in the study. Twenty-seven patients (2.9%, n=27) experienced complications classified as hematomas or seromas. In the series, significant differences were observed between the two groups according to hypocoagulation or anti-aggregation status (OR=3.62; 95% CI 1.14-11.4) (p=0.001) and the nature of histological diagnosis (toxic vs. non-toxic benign disease) (OR=6.59; 95% CI 1.83-23.7). Hypocoagulation or anti-aggregation status were independently associated with a higher risk of complications. The presence of drains was associated with longer hospitalization periods (p<0.001) and not a decreased need for reintervention.
    Conclusion: Cervical hematoma or seroma are rare complications associated with both hypocoagulation and anti-aggregation therapy and with the presence of benign toxic pathology. The use of drains does not decrease the need for reintervention and is even associated with a longer length of hospital stay; therefore, their routine use should not be advised.
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: GUIDEMOL: A Python graphical user interface for molecular descriptors based on RDKit.

    Aires-de-Sousa, Joao

    Molecular informatics

    2023  Volume 43, Issue 1, Page(s) e202300190

    Abstract: GUIDEMOL is a Python computer program based on the RDKit software to process molecular structures and calculate molecular descriptors with a graphical user interface using the tkinter package. It can calculate descriptors already implemented in RDKit as ... ...

    Abstract GUIDEMOL is a Python computer program based on the RDKit software to process molecular structures and calculate molecular descriptors with a graphical user interface using the tkinter package. It can calculate descriptors already implemented in RDKit as well as grid representations of 3D molecular structures using the electrostatic potential or voxels. The GUIDEMOL app provides easy access to RDKit tools for chemoinformatics users with no programming skills and can be adapted to calculate other descriptors or to trigger other procedures. A command line interface (CLI) is also provided for the calculation of grid representations. The source code is available at https://github.com/jairesdesousa/guidemol.
    MeSH term(s) Software ; Cheminformatics ; Adaptor Proteins, Signal Transducing
    Chemical Substances Adaptor Proteins, Signal Transducing
    Language English
    Publishing date 2023-11-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2537668-8
    ISSN 1868-1751 ; 1868-1743
    ISSN (online) 1868-1751
    ISSN 1868-1743
    DOI 10.1002/minf.202300190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Recovered Voices, Newfound Questions: Family archives and historical research

    Rosa, Maria de Lurdes / Nóvoa, Rita Sampaio da / Gago, Alice Borges / Sousa, Maria João Andrade e

    2019  

    Abstract: The book aims at presenting less known or completly unknown family archives. It proposes to question them and to analyze them under new perspectives (both from history and archival science), in order to found the "voices" if its producers - and thus to ... ...

    Abstract The book aims at presenting less known or completly unknown family archives. It proposes to question them and to analyze them under new perspectives (both from history and archival science), in order to found the "voices" if its producers - and thus to develop new research questions. It comprises three parts: "Recovering, reconstructing and (re)discovering family and personal archives"; "From a social, political and cultural history of the families to a social history of the archives"; "Public preservation and promotion of family and personal archives"
    Size 1 electronic resource (426 pages)
    Publisher Coimbra University Press
    Document type Book ; Online
    Note Family archives, Personal archives, History, Historical Archivistics ; Open Access
    HBZ-ID HT020589302
    ISBN 9789892617930 ; 9892617932
    DOI 10.14195/978-989-26-1794-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article ; Online: Correspondence on the article: "Exploring the relationship between admission pulse pressure and clinical features in patients with spontaneous supratentorial intracerebral hemorrhage".

    Navarrete, João Gabriel Bom / Sobral, Gabriel Victor Lazaro / de Sousa Santos, Matheus Abreu

    Neurosurgical review

    2024  Volume 47, Issue 1, Page(s) 66

    MeSH term(s) Humans ; Blood Pressure ; Cerebral Hemorrhage
    Language English
    Publishing date 2024-01-25
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-024-02297-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1445: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Buerger's Disease - A Clinical Case.

    Fernandes, Urânia / Vasconcelos, João / Marques, Rita / Pinto-de-Sousa, João / Almeida Pinto, João

    Portuguese journal of cardiac thoracic and vascular surgery

    2023  Volume 30, Issue 2, Page(s) 59–61

    Abstract: Buerger's disease is a distal segmental nonatherosclerotic vasculopathy that involves the inferior and superior limbs of smoker males younger than 45 years old. This article aims to describe a clinical case and revise the literature about Buerger's ... ...

    Abstract Buerger's disease is a distal segmental nonatherosclerotic vasculopathy that involves the inferior and superior limbs of smoker males younger than 45 years old. This article aims to describe a clinical case and revise the literature about Buerger's disease. A 45-year-old smoker male repeatedly visited the emergency department for refractory pain and inflammatory signs in the right hallux. After developing ulcers in the right foot, Doppler ultrasonography revealed segmental occlusion of distal arteries of that limb. It was also observed in arteriography "corkscrew" collaterals. Autoimmune, thrombophilic and cardiovascular diseases were excluded. Analgesia, antibiotics and alprostadil were implemented. As a result, the patient stopped smoking and was submitted to minor amputation with complete healing, after which he remained asymptomatic. Buerger's disease is a diagnosis of exclusion. Therefore, smoking cessation is the most effective treatment and is crucial to prevent disease progression.
    MeSH term(s) Humans ; Male ; Middle Aged ; Thromboangiitis Obliterans/diagnosis ; Arteries ; Alprostadil/therapeutic use ; Pain/drug therapy ; Smoking/adverse effects
    Chemical Substances Alprostadil (F5TD010360)
    Language English
    Publishing date 2023-07-07
    Publishing country Portugal
    Document type Journal Article
    ISSN 2184-9927
    ISSN 2184-9927
    DOI 10.48729/pjctvs.259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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