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Book: Zhong yi yu er liang fang

Shi, Fangqi

1993

Title translation	Effective pediatric formularies.
Author's details	Shi Fangqi zhu
MeSH term(s)	Pediatrics ; Drugs, Chinese Herbal/administration & dosage ; Medicine, Chinese Traditional
Language	Chinese
Size	4, 118 p.
Edition	Di 1 ban.
Publisher	Chongqing da xue chu ban she
Publishing place	Chongqing Shi
Document type	Book
ISBN	9787562406402 ; 7562406405
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Curvularin derivatives from the marine mangrove derived fungus Penicillium sumatrense MA-325.

Wang, Yi-Ran / Dong, Yu-Liang / Li, Xiao-Ming / Shi, Xiao-Shan / Li, Hong-Lei / Meng, Ling-Hong / Xu, Rui / Wang, Bin-Gui

Phytochemistry

2024 Volume 220, Page(s) 114000

Abstract: Sumalarins D-G (1-4), four previously undescribed curvularin derivatives, along with two known related metabolites, curvularin (5) and dehydrocurvularin (6), were isolated and identified from the mangrove-derived fungus Penicillium sumatrense MA-325. ... ...

Abstract	Sumalarins D-G (1-4), four previously undescribed curvularin derivatives, along with two known related metabolites, curvularin (5) and dehydrocurvularin (6), were isolated and identified from the mangrove-derived fungus Penicillium sumatrense MA-325. Among them, sumalarin D (1) represents a unique example of curvularin derivative featuring a 5-methylfuran-2-yl-methyl group. Their structures were elucidated based on analysis of NMR and MS data as well as comparison of ECD spectra and quantum chemical calculations of NMR, and compound 1 was confirmed by X-ray crystallographic analysis. Compounds 1, 2, 5, and 6 are active against aquatic pathogenic bacteria Vibrio alginolyticus and V. harveyi with MIC values ranging from 4 to 64 μg/mL, while compound 6 is cytotoxic against tumor cell lines 5673, HCT 116, 786-O, and Hela with IC
MeSH term(s)	Molecular Structure ; Penicillium/chemistry ; Antineoplastic Agents/chemistry ; Zearalenone/analogs & derivatives
Chemical Substances	curvularin (WT39K5T3BX) ; Antineoplastic Agents ; Zearalenone (5W827M159J)
Language	English
Publishing date	2024-01-24
Publishing country	England
Document type	Journal Article
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
DOI	10.1016/j.phytochem.2024.114000
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Prediction of the lymphatic, microvascular, and perineural invasion of pancreatic neuroendocrine tumors using preoperative magnetic resonance imaging.

Liu, Yu-Liang / Zhu, Hai-Bin / Chen, Mai-Lin / Sun, Wei / Li, Xiao-Ting / Sun, Ying-Shi

World journal of gastrointestinal surgery

2024 Volume 15, Issue 12, Page(s) 2809–2819

Abstract: Background: Significant correlation between lymphatic, microvascular, and perineural invasion (LMPI) and the prognosis of pancreatic neuroendocrine tumors (PENTs) was confirmed by previous studies. There was no previous study reported the relationship ... ...

Abstract	Background: Significant correlation between lymphatic, microvascular, and perineural invasion (LMPI) and the prognosis of pancreatic neuroendocrine tumors (PENTs) was confirmed by previous studies. There was no previous study reported the relationship between magnetic resonance imaging (MRI) parameters and LMPI. Aim: To determine the feasibility of using preoperative MRI of the pancreas to predict LMPI in patients with non-functioning PENTs (NFPNETs). Methods: A total of 61 patients with NFPNETs who underwent MRI scans and lymphadenectomy from May 2011 to June 2018 were included in this retrospective study. The patients were divided into group 1 ( Results: There were significant differences in the lymph node metastasis stage, tumor grade, neuron-specific enolase levels, tumor margin, main pancreatic ductal dilatation, common bile duct dilatation, enhancement pattern, vascular and adjacent tissue involvement, synchronous liver metastases, the long axis of the largest lymph node, the short axis of the largest lymph node, number of the lymph nodes with short axis > 5 or 10 mm, and tumor volume between two groups ( Conclusion: Using preoperative MRI, ill-defined tumor margins can effectively predict LMPI in patients with NF-PNETs.
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573700-4
ISSN	1948-9366
ISSN	1948-9366
DOI	10.4240/wjgs.v15.i12.2809
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The differential diagnosis of lung precursor glandular lesions, micro-invasive adenocarcinoma, and invasive adenocarcinoma using low dose spectral computed tomography perfusion imaging.

Chen, Mai-Lin / Liu, Yu-Liang / Zhu, Hai-Bin / Li, Xiao-Ting / Qi, Li-Ping / Sun, Ying-Shi

Quantitative imaging in medicine and surgery

2024 Volume 14, Issue 1, Page(s) 814–823

Abstract: Background: Few studies about the association between computed tomography (CT) perfusion imaging parameters and invasiveness in lung adenocarcinoma (LUAD) have been conducted using low dose spectral CT perfusion imaging. The purpose of this study was to ...

Abstract	Background: Few studies about the association between computed tomography (CT) perfusion imaging parameters and invasiveness in lung adenocarcinoma (LUAD) have been conducted using low dose spectral CT perfusion imaging. The purpose of this study was to investigate application of spectral revolution CT low-dose perfusion imaging in the differential diagnosis of different pathological subtypes of LUAD. Methods: This was a cross-sectional study based on historical data from January 2018 to May 2019 in Peking University Cancer Hospital & Institute. A total of 62 cases were enrolled, including 2 cases of atypical adenomatous hyperplasia (AAH), 3 cases of adenocarcinoma in situ (AIS), 4 cases of minimally invasive adenocarcinoma (MIA), and 53 cases of invasive adenocarcinoma (IAC), all confirmed with pathology. The inclusion and exclusion criteria were regulated. Using Revolution low-dose CT perfusion imaging (GE, USA), the CT perfusion parameters of hemodynamics were obtained: blood flow (BF), blood volume (BV), impulse residue function time of arrival (IRF TO), maximum slope of increase (MSI), mean transit time (MTT), permeability surface area product (PS), positive enhancement integral (PEI), and maximum enhancement time (Tmax). Univariate analysis of variance (ANOVA) or Kruskal-Wallis test was used to compare the differences of CT perfusion quantitative parameters among AAH, AIS, MIA, and IAC. Mann-Whitney test was used to compare the difference of CT perfusion imaging parameters between preinvasive lesions (AAH and AIS) and invasive lung cancer (MIA and IAC). Results: Statistically significant differences in IRF TO were observed in LUAD with different invasiveness, namely, among AIS, MIA, and IAC groups (0.56±0.74 Conclusions: The low-dose perfusion parameter IRF TO of revolution CT has the potential to be employed in the differential diagnosis of different pathological subtypes of LUAD.
Language	English
Publishing date	2024-01-02
Publishing country	China
Document type	Journal Article
ZDB-ID	2653586-5
ISSN	2223-4306 ; 2223-4292
ISSN (online)	2223-4306
ISSN	2223-4292
DOI	10.21037/qims-23-487
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diketopiperazine Alkaloids and Bisabolene Sesquiterpenoids from

Dong, Yu-Liang / Li, Xiao-Ming / Shi, Xiao-Shan / Wang, Yi-Ran / Wang, Bin-Gui / Meng, Ling-Hong

Marine drugs

2023 Volume 21, Issue 5

Abstract: Two new quinazolinone diketopiperazine alkaloids, including versicomide E ( ...

Abstract	Two new quinazolinone diketopiperazine alkaloids, including versicomide E (
MeSH term(s)	Animals ; Diketopiperazines/chemistry ; Anthozoa ; Molecular Structure ; Fungi ; Alkaloids/chemistry ; Anti-Bacterial Agents/chemistry ; Sesquiterpenes
Chemical Substances	Diketopiperazines ; Alkaloids ; Anti-Bacterial Agents ; Sesquiterpenes
Language	English
Publishing date	2023-05-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175190-0
ISSN	1660-3397 ; 1660-3397
ISSN (online)	1660-3397
ISSN	1660-3397
DOI	10.3390/md21050293
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The integration of bulk and single-cell sequencing data revealed the function of FKBP10 in the gastric cancer microenvironment.

Xie, Manling / Liang, Liang / Yu, Liuying / Shi, Jiping / Lei, Yu / Huang, Jun / Cai, Xiaoyong

Translational cancer research

2024 Volume 13, Issue 2, Page(s) 975–988

Abstract: Background: Due to the implementation of individualized treatment, the majority of gastric cancer patients have a favorable prognosis, but advanced gastric cancer with recurrence and distant metastasis still plagues some patients. As a member of the ... ...

Abstract	Background: Due to the implementation of individualized treatment, the majority of gastric cancer patients have a favorable prognosis, but advanced gastric cancer with recurrence and distant metastasis still plagues some patients. As a member of the FK506-binding protein (FKBP65) family, there is growing evidence that FKBP10 plays a crucial role in tumorigenesis. However, the role of FKBP10 in the tumor microenvironment (TME) has been a prominent issue. Methods: The FKBP10 knockdown efficiency in gastric cancer cells was determined by quantitative real-time polymerase chain reaction (qRT-PCR). Wound healing and transwell analysis were performed to detect variations in cell invasion and migration. We integrated single-cell and bulk sequencing data to further elaborate the impact of FKBP10 and FKBP10-coexpressed genes (FCGs) in the TME via a variety of bioinformatics approaches. Results: Here, we found that FKBP10 knockdown inhibited cell invasion and metastasis. FKBP10 was chiefly expressed in inflammatory cancer-associated fibroblasts (iCAFs), and FCGs principally mediated alterations in extracellular matrix (ECM) organization. Besides, according to nine prognosis-related FCGs, two disparate clusters were identified, and differences in tumor immune infiltration characteristics and immunotherapy response between different clusters were investigated. Conclusions: Our study provides insights into the expression and function of FKBP10 in the microenvironment of gastric cancer.
Language	English
Publishing date	2024-02-02
Publishing country	China
Document type	Journal Article
ZDB-ID	2901601-0
ISSN	2219-6803 ; 2218-676X
ISSN (online)	2219-6803
ISSN	2218-676X
DOI	10.21037/tcr-23-1484
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Strain-tunable electronic structure and anisotropic transport properties in Janus MoSSe and g-SiC van der Waals heterostructure.

Liu, Yu-Liang / Zhao, Wen-Kai / Shi, Ying / Yang, Chuan-Lu

Physical chemistry chemical physics : PCCP

2021 Volume 23, Issue 15, Page(s) 9440–9447

Abstract: The van der Waals heterostructures (vdWHs) create a multi-purpose platform to design unique structures for efficient photovoltaic and optoelectronic applications. In this study, on the basis of the first-principles calculations, we present a type-II ... ...

Abstract	The van der Waals heterostructures (vdWHs) create a multi-purpose platform to design unique structures for efficient photovoltaic and optoelectronic applications. In this study, on the basis of the first-principles calculations, we present a type-II semiconducting MoSSe/g-SiC vdWH with a moderate bandgap value of 1.31 eV. In particular, the large conduction band offset of 1.18 eV and valence band offset of 0.90 eV are distinguished, which can act as powerful driving forces to promote interlayer charge transfer. Moreover, MoSSe/g-SiC vdWH possesses high carrier mobilities and anisotropic transport properties with a larger transport current along the zigzag direction. More importantly, tensile strain can transform indirect into direct band gap and enhance the visible-light absorption while sustaining type-II band alignment. These results reveal the new physical nature of MoSSe/g-SiC vdWH and demonstrate its practical application potential in photovoltaics and optoelectronic nanodevices.
Language	English
Publishing date	2021-04-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d1cp00483b
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Histogram array and convolutional neural network of DWI for differentiating pancreatic ductal adenocarcinomas from solid pseudopapillary neoplasms and neuroendocrine neoplasms.

Shi, Yan-Jie / Zhu, Hai-Tao / Li, Xiao-Ting / Zhang, Xiao-Yan / Liu, Yu-Liang / Wei, Yi-Yuan / Sun, Ying-Shi

Clinical imaging

2023 Volume 96, Page(s) 15–22

Abstract: Purpose: This study aimed to investigate the diagnostic performance of the histogram array and convolutional neural network (CNN) based on diffusion-weighted imaging (DWI) with multiple b-values under magnetic resonance imaging (MRI) to distinguish ... ...

Abstract	Purpose: This study aimed to investigate the diagnostic performance of the histogram array and convolutional neural network (CNN) based on diffusion-weighted imaging (DWI) with multiple b-values under magnetic resonance imaging (MRI) to distinguish pancreatic ductal adenocarcinomas (PDACs) from solid pseudopapillary neoplasms (SPNs) and pancreatic neuroendocrine neoplasms (PNENs). Methods: This retrospective study consisted of patients diagnosed with PDACs (n = 132), PNENs (n = 45) and SPNs (n = 54). All patients underwent 3.0-T MRI including DWI with 10 b values. The regions of interest (ROIs) of pancreatic tumor were manually drawn using ITK-SNAP software, which included entire tumor at DWI (b = 1500 s/m Results: The area under the curves (AUCs) of the histogram array and the CNN model for differentiating PDACs from PNENs and SPNs were 0.896, 0.846, and 0.839 in the training, validation and testing cohorts, respectively. The accuracy, sensitivity and specificity were 90.22%, 96.23%, and 82.05% in the training cohort, 84.78%, 96.15%, and 70.0% in the validation cohort, and 81.72%, 90.57%, and 70.0% in the testing cohort. The performance of CNN with AUC of 0.865 for this differentiation was significantly higher than that of f with AUC = 0.755 (P = 0.0057) and α with AUC = 0.776 (P = 0.0278) in all patients. Conclusion: The histogram array and CNN based on DWI data with multiple b-values using MRI provided an accurate diagnostic performance to differentiate PDACs from PNENs and SPNs.
MeSH term(s)	Humans ; Retrospective Studies ; Pancreatic Neoplasms/pathology ; Diffusion Magnetic Resonance Imaging/methods ; Carcinoma, Pancreatic Ductal/pathology ; Magnetic Resonance Imaging/methods ; Neuroendocrine Tumors/pathology ; Neural Networks, Computer ; Pancreatic Neoplasms
Language	English
Publishing date	2023-01-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2023.01.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Characteristics of tunable aluminum-doped Ga

Ding, Si-Tong / Chen, Yu-Chang / Yu, Qiu-Jun / Zeng, Guang / Shi, Cai-Yu / Shen, Lei / Zhao, Xue-Feng / Lu, Hong-Liang

Nanotechnology

2024 Volume 35, Issue 15

Abstract: Aluminum-doped ... ...

Abstract	Aluminum-doped Ga
Language	English
Publishing date	2024-01-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1362365-5
ISSN	1361-6528 ; 0957-4484
ISSN (online)	1361-6528
ISSN	0957-4484
DOI	10.1088/1361-6528/ad1afc
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Article ; Online: Oxepine-containing pyrazinopyrimidine alkaloids and quinolinone derivatives produced by Aspergillus versicolor AS-212, a deep-sea-derived endozoic fungus.

Dong, Yu-Liang / Li, Xiao-Ming / Wang, Yi-Ran / Shi, Xiao-Shan / Wang, Bin-Gui / Meng, Ling-Hong

Fitoterapia

2023 Volume 168, Page(s) 105559

Abstract: Four new oxepine-containing pyrazinopyrimidine alkaloids, versicoxepines A - D (1-4), two quinolinone alkaloid analogs including 3-hydroxy-6-methoxy-4-phenylquinolin-2(1H)-one (5) and 3-methoxy-6-hydroxy-4-phenylquinolin-2(1H)-one (6) which were new ... ...

Abstract	Four new oxepine-containing pyrazinopyrimidine alkaloids, versicoxepines A - D (1-4), two quinolinone alkaloid analogs including 3-hydroxy-6-methoxy-4-phenylquinolin-2(1H)-one (5) and 3-methoxy-6-hydroxy-4-phenylquinolin-2(1H)-one (6) which were new naturally occurring compounds, together with two known compounds (7 and 8) were isolated from Aspergillus versicolor AS-212, an endozoic fungus isolated from the deep-sea coral Hemicorallium cf. imperiale, which was collected from the Magellan Seamounts in the Western Pacific Ocean. Their structures were determined by extensive analysis of the spectroscopic and X-ray crystallographic data as well as by chiral HPLC analysis, ECD calculation, and DP4+ probability prediction. Structurally, versicoxepines B and C (2 and 3) represent the first example of a new oxepine-containing pyrazinopyrimidine alkaloid whose cyclic dipeptide moiety is composed of the same type of amino acid (Val or Ile). Compound 5 displayed antibacterial activity against aquatic pathogens, Vibrio harveyi and V. alginolyticus, with MICs of 8 μg/mL.
MeSH term(s)	Alkaloids/chemistry ; Alkaloids/isolation & purification ; Alkaloids/pharmacology ; Aspergillus/chemistry ; Molecular Structure ; Oxepins/chemistry ; Quinolones/chemistry ; Quinolones/isolation & purification ; Quinolones/pharmacology ; Pacific Ocean ; Crystallography, X-Ray ; Anti-Bacterial Agents/pharmacology ; Vibrio/drug effects ; Magnetic Resonance Spectroscopy
Chemical Substances	Alkaloids ; Oxepins ; Quinolones ; Anti-Bacterial Agents
Language	English
Publishing date	2023-06-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2023.105559
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