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  1. Article ; Online: Is Corneal Arcus Independently Associated With Incident Cardiovascular Disease in Asians?

    Masoumpour, Masoumeh B / Jafari, Peyman

    American journal of ophthalmology

    2018  Volume 188, Page(s) 184–185

    MeSH term(s) Arcus Senilis ; Asian Continental Ancestry Group ; Cardiovascular Diseases ; Humans
    Language English
    Publishing date 2018-02-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2017.12.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Current and Future Techniques in Wound Healing Modulation after Glaucoma Filtering Surgeries.

    Masoumpour, Masoumeh B / Nowroozzadeh, M Hossein / Razeghinejad, M Reza

    The open ophthalmology journal

    2016  Volume 10, Page(s) 68–85

    Abstract: Filtering surgeries are frequently used for controlling intraocular pressure in glaucoma patients. The long-term success of operation is intimately influenced by the process of wound healing at the site of surgery. Indeed, if has not been anticipated and ...

    Abstract Filtering surgeries are frequently used for controlling intraocular pressure in glaucoma patients. The long-term success of operation is intimately influenced by the process of wound healing at the site of surgery. Indeed, if has not been anticipated and managed accordingly, filtering surgery in high-risk patients could end up in bleb failure. Several strategies have been developed so far to overcome excessive scarring after filtering surgery. The principal step involves meticulous tissue handling and modification of surgical technique, which can minimize the severity of wound healing response at the first place. However, this is usually insufficient, especially in those with high-risk criteria. Thus, several adjuvants have been tried to stifle the exuberant scarring after filtration surgery. Conventionally, corticosteroids and anti-fibrotic agents (including 5-fluorouracil and Mitomycin-C) have been used for over three decades with semi-acceptable outcomes. Blebs and bleb associated complications are catastrophic side effects of anti-fibrotic agents, which occasionally are encountered in a subset of patients. Therefore, research continues to find a safer, yet effective adjuvant for filtering surgery. Recent efforts have primarily focused on selective inhibition of growth factors that promote scarring during wound healing process. Currently, only anti-VEGF agents have gained widespread acceptance to be translated into routine clinical practice. Robust evidence for other agents is still lacking and future confirmative studies are warranted. In this review, we explain the importance of wound healing process during filtering surgery, and describe the conventional as well as potential future adjuvants for filtration surgeries.
    Language English
    Publishing date 2016-02-29
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2395991-5
    ISSN 1874-3641
    ISSN 1874-3641
    DOI 10.2174/1874364101610010068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Evaluation of topical bevacizumab as an adjunct to mitomycin C augmented trabeculectomy.

    Zarei, Reza / Masoumpour, Masoumeh / Moghimi, Sasan / Fakhraei, Ghasem / Eslami, Yadollah / Mohammadi, Masoud

    Journal of current ophthalmology

    2016  Volume 29, Issue 2, Page(s) 85–91

    Abstract: ... mg/mL) was used for 2 weeks 4 times daily in group A. Patients in group B received routine ...

    Abstract Purpose: To investigate the safety and synergistic effect of topical bevacizumab after trabeculectomy surgery with mitomycin C (MMC).
    Methods: In this prospective, non-randomized, comparative interventional study, 40 eyes from 40 patients with uncontrolled open-angle glaucoma were studied after they underwent primary trabeculectomy with mitomycin C (0.02% for 2 min). Following the procedure topical bevacizumab (4 mg/mL) was used for 2 weeks 4 times daily in group A. Patients in group B received routine postoperative care. The outcome measures were the intraocular pressure (IOP), number of anti-glaucoma medications, complications, and bleb evaluation.
    Results: Of the 32 eyes that had at least 6 months follow-up, 16 were treated with adjuvant topical bevacizumab. The mean preoperative IOP in group A improved from 26.7 ± 9.3 mmHg with 2.8 ± 1.3 anti-glaucoma medications to 10.5 ± 2.8 mmHg with 0.7 ± 1 anti-glaucoma medications at last follow-up (
    Conclusion: Administration of topical bevacizumab 4 mg/ml for two weeks following trabeculectomy with mitomycin-C did not significantly affect the IOP trend, but significantly decreased the cystic bleb formation in short-term follow-up.
    Language English
    Publishing date 2016-12-27
    Publishing country India
    Document type Journal Article
    ISSN 2452-2325
    ISSN 2452-2325
    DOI 10.1016/j.joco.2016.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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