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  1. Book ; Audio / Video: Cloning Adam's rib

    Evans, John H

    a primer on religious responses to cloning

    2002  

    Institution Pew Forum on Religion and Public Life
    Author's details a report prepared for the Pew Forum on Religion and Public Life by John H. Evans
    MeSH term(s) Cloning, Organism/ethics ; Religion and Medicine ; Catholicism ; Embryo Research ; Islam ; Judaism ; Protestantism ; Public Policy ; Stem Cells
    Keywords United States ; Biomedical and Behavioral Research ; Genetics and Reproduction ; Religious Approach
    Language English
    Publisher Pew Forum on Religion and Public Life
    Publishing place Washington, DC
    Document type Book ; Audio / Video
    Note Title from PDF t.p. (viewed on Jan. 5, 2005). ; October 2002.
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article ; Online: Weight Bias in Reproductive Medicine: A Curiously Unexplored Frontier.

    Evans, Adam T / Vitek, Wendy S

    Seminars in reproductive medicine

    2023  Volume 41, Issue 3-04, Page(s) 63–69

    Abstract: Obesity has been associated with a multitude of medical comorbidities, infertility, and adverse obstetric outcomes. Weight stigma and weight bias pervade not only the medical field but also education, employment, and activities of daily living. The ... ...

    Abstract Obesity has been associated with a multitude of medical comorbidities, infertility, and adverse obstetric outcomes. Weight stigma and weight bias pervade not only the medical field but also education, employment, and activities of daily living. The experience of weight stigma has been shown to adversely impact not only the mental health of individuals with overweight or obesity but also worsen obesogenic behaviors, and medical comorbidities. This review frames the rise of weight stigma and weight bias within the context of the "obesity epidemic" and explores its associations with infertility and decreased access to health care and its subsequent impact on the lives of individuals. Furthermore, it explores the concepts of intrinsic and extrinsic weight stigma/bias and highlights the need for further examination and research into the impact of these factors on access to reproductive medicine and subsequent outcomes.
    MeSH term(s) Female ; Pregnancy ; Humans ; Weight Prejudice ; Activities of Daily Living ; Obesity/complications ; Obesity/epidemiology ; Overweight/complications ; Overweight/epidemiology ; Overweight/psychology ; Reproductive Medicine ; Infertility/therapy ; Body Weight
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2042479-6
    ISSN 1526-4564 ; 1526-8004
    ISSN (online) 1526-4564
    ISSN 1526-8004
    DOI 10.1055/s-0043-1777016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Stroke Mortality and Stroke Hospitalizations: Racial Differences and Similarities in the Geographic Patterns of High Burden Communities Among Older Adults.

    Evans, Kirsten / Casper, Michele / Schieb, Linda / DeLara, David / Vaughan, Adam S

    Preventing chronic disease

    2024  Volume 21, Page(s) E26

    MeSH term(s) Humans ; United States/epidemiology ; Aged ; Race Factors ; Stroke/epidemiology ; Black or African American ; Hospitalization
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2135684-1
    ISSN 1545-1151 ; 1545-1151
    ISSN (online) 1545-1151
    ISSN 1545-1151
    DOI 10.5888/pcd21.230339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Weight Bias in Reproductive Medicine: A Curiously Unexplored Frontier

    Evans, Adam T. / Vitek, Wendy S.

    Seminars in Reproductive Medicine

    (Obesity and Reproduction)

    2023  Volume 41, Issue 03/04, Page(s) 63–69

    Abstract: Obesity has been associated with a multitude of medical comorbidities, infertility, and adverse obstetric outcomes. Weight stigma and weight bias pervade not only the medical field but also education, employment, and activities of daily living. The ... ...

    Series title Obesity and Reproduction
    Abstract Obesity has been associated with a multitude of medical comorbidities, infertility, and adverse obstetric outcomes. Weight stigma and weight bias pervade not only the medical field but also education, employment, and activities of daily living. The experience of weight stigma has been shown to adversely impact not only the mental health of individuals with overweight or obesity but also worsen obesogenic behaviors, and medical comorbidities. This review frames the rise of weight stigma and weight bias within the context of the “obesity epidemic” and explores its associations with infertility and decreased access to health care and its subsequent impact on the lives of individuals. Furthermore, it explores the concepts of intrinsic and extrinsic weight stigma/bias and highlights the need for further examination and research into the impact of these factors on access to reproductive medicine and subsequent outcomes.
    Keywords obesity ; weight stigma ; weight bias ; infertility ; access to care
    Language English
    Publishing date 2023-07-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2042479-6
    ISSN 1526-4564 ; 1526-8004
    ISSN (online) 1526-4564
    ISSN 1526-8004
    DOI 10.1055/s-0043-1777016
    Database Thieme publisher's database

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  5. Article: Somatic mutation as an explanation for epigenetic aging.

    Koch, Zane / Li, Adam / Evans, Daniel S / Cummings, Steven / Ideker, Trey

    bioRxiv : the preprint server for biology

    2023  

    Abstract: DNA methylation marks have recently been used to build models known as "epigenetic clocks" which predict calendar age. As methylation of cytosine promotes C-to-T mutations, we hypothesized that the methylation changes observed with age should reflect the ...

    Abstract DNA methylation marks have recently been used to build models known as "epigenetic clocks" which predict calendar age. As methylation of cytosine promotes C-to-T mutations, we hypothesized that the methylation changes observed with age should reflect the accrual of somatic mutations, and the two should yield analogous aging estimates. In analysis of multimodal data from 9,331 human individuals, we find that CpG mutations indeed coincide with changes in methylation, not only at the mutated site but also with pervasive remodeling of the methylome out to ±10 kilobases. This one-to-many mapping enables mutation-based predictions of age that agree with epigenetic clocks, including which individuals are aging faster or slower than expected. Moreover, genomic loci where mutations accumulate with age also tend to have methylation patterns that are especially predictive of age. These results suggest a close coupling between the accumulation of sporadic somatic mutations and the widespread changes in methylation observed over the course of life.
    Language English
    Publishing date 2023-12-09
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.12.08.569638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Therapeutic Targeting of P53: A Comparative Analysis of APR-246 and COTI-2 in Human Tumor Primary Culture 3-D Explants.

    Nagourney, Adam J / Gipoor, Joshua B / Evans, Steven S / D'Amora, Paulo / Duesberg, Max S / Bernard, Paula J / Francisco, Federico / Nagourney, Robert A

    Genes

    2023  Volume 14, Issue 3

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Female ; Humans ; Cisplatin ; Tumor Suppressor Protein p53/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Ovarian Neoplasms/drug therapy
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Tumor Suppressor Protein p53 ; Antineoplastic Agents ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2023-03-19
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes14030747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pain in the ICU; Can We Adequately Treat What We Can't Hear?

    Khelemsky, Yury / Evans, Adam S

    Journal of cardiothoracic and vascular anesthesia

    2017  Volume 31, Issue 4, Page(s) 1153–1154

    Language English
    Publishing date 2017
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2017.04.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 31: Show issues

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  8. Article ; Online: Elucidating the mechanism of photochemical CO

    Cohen, Kailyn Y / Reinhold, Adam / Evans, Rebecca / Lee, Tia S / Kuo, Hsin-Ya / Nedd, Delaan G / Scholes, Gregory D / Bocarsly, Andrew B

    Dalton transactions (Cambridge, England : 2003)

    2022  Volume 51, Issue 45, Page(s) 17203–17215

    Abstract: The complex, [{[Mn(bpy)(CO) ...

    Abstract The complex, [{[Mn(bpy)(CO)
    Language English
    Publishing date 2022-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d2dt02506j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Nerve blocks for occipital headaches: A systematic review and meta-analysis.

    Evans, Adam G / Joseph, Kardeem S / Samouil, Marc M / Hill, Dorian S / Ibrahim, Maryo M / Assi, Patrick E / Joseph, Jeremy T / Kassis, Salam Al

    Journal of anaesthesiology, clinical pharmacology

    2023  Volume 39, Issue 2, Page(s) 170–180

    Abstract: Migraine surgeons have identified six "trigger sites" where cranial nerve compression may trigger a migraine. This study investigates the change in headache severity and frequency following nerve block of the occipital trigger site. This PRISMA-compliant ...

    Abstract Migraine surgeons have identified six "trigger sites" where cranial nerve compression may trigger a migraine. This study investigates the change in headache severity and frequency following nerve block of the occipital trigger site. This PRISMA-compliant systematic review of five databases searched from database inception through May 2020 is registered under the PROSPERO ID: CRD42020199369. Only randomized controlled trials utilizing injection treatments for headaches with pain or tenderness in the occipital scalp were included. Pain severity was scored from 0 to 10. Headache frequency was reported as days per week. Included were 12 RCTs treating 586 patients of mean ages ranging from 33.7 to 55.8 years. Meta-analyses of pain severity comparing nerve blocks to baseline showed statistically significant reductions of 2.88 points at 5 to 20 min, 3.74 points at 1 to 6 weeks, and 1.07 points at 12 to 24 weeks. Meta-analyses of pain severity of nerve blocks compared with treatment groups of neurolysis, pulsed radiofrequency, and botulinum toxin type A showed similar headache pain severity at 1 to 2 weeks, and inferior improvements compared with the treatment groups after 2 weeks. Meta-analyses of headache frequency showed statistically significant reductions at 1 to 6-week follow-ups as compared with baseline and at 1 to 6 weeks as compared with inactive control injections. The severity and frequency of occipital headaches are reduced following occipital nerve blocks. This improvement is used to predict the success of migraine surgery. Future research should investigate spinous process injections with longer follow-up.
    Language English
    Publishing date 2023-04-25
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.JOACP_62_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4830: Show issues Location:
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  10. Article: Overnight Melatonin Concentration and Sleep Quality Are Associated with the Clinical Features of Polycystic Ovary Syndrome.

    Evans, Adam T / Vanden Brink, Heidi / Lim, Jessica S / Jarrett, Brittany Y / Lin, Annie W / Lujan, Marla E / Hoeger, Kathleen

    Biomedicines

    2023  Volume 11, Issue 10

    Abstract: Circulating melatonin is elevated in women with polycystic ovary syndrome (PCOS); whether circadian disruptions coincide with sleep disturbances in women with PCOS or their symptom severity is unclear. The objective of this observational pilot study was ... ...

    Abstract Circulating melatonin is elevated in women with polycystic ovary syndrome (PCOS); whether circadian disruptions coincide with sleep disturbances in women with PCOS or their symptom severity is unclear. The objective of this observational pilot study was to determine whether altered patterns of melatonin excretion are associated with reduced sleep quality in women with versus without PCOS. Participants underwent a clinical assessment, transvaginal ultrasound, and reproductive hormone testing. Morning and evening urine samples were assayed for urinary 6-sulfatoxymelatonin (MEL) as a proxy for melatonin production. The night (morning MEL)-to-day (evening MEL) ratio, or N:D ratio, was determined to approximate the rhythm of MEL production. Sleep quality and duration were assessed using the Pittsburgh Sleep Quality Index (PSQI) and wrist actigraphy. No differences were detected in overnight MEL, daytime MEL, or the N:D ratio in participants with PCOS versus controls. The PCOS group experienced reduced weekend sleep efficiency vs. controls (81% vs. 88%
    Language English
    Publishing date 2023-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11102763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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