LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU=Butros Linda
  2. AU=CASTORENA-GONZALEZ JORGE A.
  3. AU=Grtsch Bettina
  4. AU="José M. Ramada"
  5. AU="Parashar, Prashant"

Search results

Result 1 - 8 of total 8

Search options

  1. Article: Concurrent t(4;11) and t(1:19) in a Pediatric Patient with B-Lymphoblastic Leukemia/Lymphoma (B-ALL): A Case Report and Review of the Literature.

    Insuasti-Beltran, Giovanni / Butros, Linda / Foucar, Kathryn

    Journal of the Association of Genetic Technologists

    2015  Volume 39, Issue 4, Page(s) 195–197

    Abstract: We herein present the case of a pediatric patient with B-lymphoblastic leukemia (B-ALL) with MLL gene rearrangement associated with the t(4;11)(q21;q23). Complete remission was achieved with standard B-ALL-directed chemotherapy and whole brain radiation. ...

    Abstract We herein present the case of a pediatric patient with B-lymphoblastic leukemia (B-ALL) with MLL gene rearrangement associated with the t(4;11)(q21;q23). Complete remission was achieved with standard B-ALL-directed chemotherapy and whole brain radiation. The patient subsequently relapsed and cytogenetic assessment revealed an additional acquired t(1;19)(q23;p13) associated with the TCF3-PBX1 fusion. After reinduction chemotherapy with a relapse B-ALL protocol the patient achieved disease remission; however, he developed respiratory complications and died. This represents a unique case as these two translocations have never been described concurrently in pediatric acute leukemia patients.
    Language English
    Publishing date 2015-06-01
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7834
    ISSN 1523-7834
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa.

    Butros, Linda / Boayue, Koh / Mathew, Prasad

    Drug design, development and therapy

    2011  Volume 5, Page(s) 275–282

    Abstract: Bypassing agents are the mainstay of treatment for patients with hemophilia with high-titer inhibitors. Whereas the availability of these agents has greatly advanced the management of bleeding episodes in this population, timely administration of ... ...

    Abstract Bypassing agents are the mainstay of treatment for patients with hemophilia with high-titer inhibitors. Whereas the availability of these agents has greatly advanced the management of bleeding episodes in this population, timely administration of bypassing agents continues to be hampered by a number of practical limitations, including the need for refrigerated storage of the agent and its reconstitution at room temperature prior to administration, among others. In this review, the importance of early treatment of bleeds and factors that influence this more timely therapeutic approach are highlighted, together with the advantages offered by the use of a new formulation of recombinant activated factor VII that permits improved storage and portability, potentially optimizing timely bypassing agent administration.
    MeSH term(s) Drug Compounding/methods ; Drug Stability ; Drug Storage ; Factor VIIa/administration & dosage ; Factor VIIa/therapeutic use ; Hemophilia A/drug therapy ; Hemophilia A/physiopathology ; Humans ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/therapeutic use ; Temperature ; Time Factors
    Chemical Substances Recombinant Proteins ; recombinant FVIIa (AC71R787OV) ; Factor VIIa (EC 3.4.21.21)
    Language English
    Publishing date 2011-05-12
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2451346-5
    ISSN 1177-8881 ; 1177-8881
    ISSN (online) 1177-8881
    ISSN 1177-8881
    DOI 10.2147/DDDT.S17722
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Novel compound VHL heterozygosity (VHL T124A/L188V) associated with congenital polycythaemia.

    Lorenzo, Felipe R / Yang, Chunzhang / Lanikova, Lucie / Butros, Linda / Zhuang, Zhengping / Prchal, Josef T

    British journal of haematology

    2013  Volume 162, Issue 6, Page(s) 851–853

    MeSH term(s) Adolescent ; Child ; Female ; Heterozygote ; Humans ; Male ; Polycythemia/congenital ; Polycythemia/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/genetics
    Chemical Substances Von Hippel-Lindau Tumor Suppressor Protein (EC 2.3.2.27) ; VHL protein, human (EC 6.3.2.-)
    Language English
    Publishing date 2013-06-17
    Publishing country England
    Document type Case Reports ; Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.12431
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Intracranial hemorrhage in immune thrombocytopenic purpura: a retrospective analysis.

    Butros, Linda J / Bussel, James B

    Journal of pediatric hematology/oncology

    2003  Volume 25, Issue 8, Page(s) 660–664

    Abstract: Purpose: To ascertain characteristics of children with immune thrombocytopenic purpura (ITP) and intracranial hemorrhage (ICH).: Methods: The authors identified 75 published cases of ICH in children with ITP by review of the literature from 1954 to ... ...

    Abstract Purpose: To ascertain characteristics of children with immune thrombocytopenic purpura (ITP) and intracranial hemorrhage (ICH).
    Methods: The authors identified 75 published cases of ICH in children with ITP by review of the literature from 1954 to 1998. Data pertaining to the ICH was recorded for age, gender, time from diagnosis of ITP (to ICH), platelet count, head trauma or arteriovenous malformation, concomitant medications, associated infections, other bleeding manifestations, prior treatment, and outcome. RESULTS Sixty-two cases represented 6 months to 20 years of age; 65% of patients were female. The median time from the diagnosis of ITP to ICH was 32 days (range 0 days to 8 years). Fifty of 69 ICH cases (72%) occurred within 6 months of diagnosis, but only 7 (10%) occurred within 3 days of diagnosis. The platelet count was less than 10000/microL in 71.4% of the cases. Treatment prior to the ICH was primarily steroids but also included intravenous immune globulin (IVIG), splenectomy, and others (interferon, azathioprine, or vincristine). There was no difference in mortality of patients before (56%) or after (54%) 1980.
    Conclusions: A very low platelet count appears permissive but not sufficient for ICH to occur in children with ITP. ICH occurs more commonly in acute ITP but can occur years after diagnosis. A significant number of patients develop an ICH despite having already initiated steroid treatment of ITP.
    MeSH term(s) Adolescent ; Adult ; Age of Onset ; Cerebral Hemorrhage/etiology ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Platelet Count ; Prognosis ; Purpura, Thrombocytopenic, Idiopathic/complications ; Purpura, Thrombocytopenic, Idiopathic/drug therapy ; Retrospective Studies ; Risk Factors ; Steroids/therapeutic use
    Chemical Substances Steroids
    Language English
    Publishing date 2003-07-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/00043426-200308000-00017
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1537: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: The meaning of surviving cancer for Latino adolescents and emerging young adults.

    Jones, Barbara L / Volker, Deborah L / Vinajeras, Yolanda / Butros, Linda / Fitchpatrick, Cynthia / Rossetto, Kelly

    Cancer nursing

    2009  Volume 33, Issue 1, Page(s) 74–81

    Abstract: Adolescent and young adult (AYA) survivors of cancer are an understudied population with unique developmental and medical needs that extend well beyond their active treatment. Survivors diagnosed as AYAs may experience both physical and emotional late ... ...

    Abstract Adolescent and young adult (AYA) survivors of cancer are an understudied population with unique developmental and medical needs that extend well beyond their active treatment. Survivors diagnosed as AYAs may experience both physical and emotional late effects. In particular, the experiences of Latino cancer survivors have not been explored. The purpose of this study was to conduct interviews with AYA Latino cancer survivors to inform professionals working with these survivors. A hermeneutic phenomenological approach was selected based on the focus on experiences and meanings of Latino adolescents' cancer survivorship. Phenomenology allows for understanding the subjective meaning and lived experience of populations that are understudied or marginalized. In-depth interviews were conducted with participants. Enrolled in the study were Latino AYAs between the ages of 14 and 21 years, after treatment. Interviews revealed 7 themes regarding the experience and meaning of survivorship for this population: gratitude, humor/positive attitude, empathy for younger children with cancer, God and faith, cancer happens for a reason/cancer changed my life, familial support, and staff relationships. Latino AYA cancer survivors develop meaning out of unique cancer experiences. Programs need to be developed specifically to address Latino adolescents and young adult survivors of cancer.
    MeSH term(s) Adaptation, Psychological ; Adolescent ; Adult ; Age Factors ; Child ; Female ; Health Knowledge, Attitudes, Practice ; Hispanic or Latino ; Humans ; Male ; Neoplasms/diagnosis ; New Mexico ; Pilot Projects ; Psychometrics ; Stress, Psychological ; Survivors ; Texas ; United States ; Young Adult
    Language English
    Publishing date 2009-11-24
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 391995-x
    ISSN 1538-9804 ; 0162-220X
    ISSN (online) 1538-9804
    ISSN 0162-220X
    DOI 10.1097/NCC.0b013e3181b4ab8f
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1538: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Delayed diagnosis of retinoblastoma: analysis of degree, cause, and potential consequences.

    Butros, Linda J / Abramson, David H / Dunkel, Ira J

    Pediatrics

    2002  Volume 109, Issue 3, Page(s) E45

    Abstract: Objective: To assess the degree, cause, and consequence of delays from presenting signs to diagnosis of retinoblastoma.: Methods: A retrospective chart review was conducted of 64 consecutive patients who presented to the Memorial Sloan-Kettering ... ...

    Abstract Objective: To assess the degree, cause, and consequence of delays from presenting signs to diagnosis of retinoblastoma.
    Methods: A retrospective chart review was conducted of 64 consecutive patients who presented to the Memorial Sloan-Kettering Cancer Center with newly diagnosed retinoblastoma. Seven patients with a positive family history were excluded.
    Results: The median times from presenting signs to diagnosis for patients with unilateral and bilateral disease were 1.5 and 2.25 months (range: 0--46), respectively; for those who presented with leukocoria and strabismus, median times were 1.5 (range: 0--46) and 2.5 months (range: 0--24). Parents noted the first signs in 75% of the cases. Seventy-seven percent delayed seeking treatment, and primary care physicians (PCPs) delayed referral in 30%. Only 3 patients were referred from PCPs solely for physical examination findings. No adverse consequence of delayed diagnosis could be established clearly, but a trend toward eye loss being associated with longer delays in patients with bilateral retinoblastoma was noted.
    Conclusion: Leukocoria and strabismus secondary to retinoblastoma are usually first recognized by relatives rather than PCPs. At routine visits, PCPs should inform parents about the importance of reporting eye abnormalities, and children whose parents complain of leukocoria (white, shiny, jello-like eye) should be referred promptly to an ophthalmologist regardless of whether an absent red reflex is appreciated.
    MeSH term(s) Child ; Child, Preschool ; Humans ; Infant ; Pupil Disorders/etiology ; Referral and Consultation ; Reflex, Pupillary ; Retinal Neoplasms/complications ; Retinal Neoplasms/diagnosis ; Retinal Neoplasms/therapy ; Retinoblastoma/complications ; Retinoblastoma/diagnosis ; Retinoblastoma/therapy ; Retrospective Studies ; Strabismus/etiology ; Time Factors
    Language English
    Publishing date 2002-03-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.109.3.e45
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 357: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors

    Butros L / Boayue K / Mathew P

    Drug Design, Development and Therapy, Vol 2011, Iss default, Pp 275-

    a new and practical formulation of recombinant factor VIIa

    2011  Volume 282

    Abstract: Linda Butros, Koh Boayue, Prasad MathewThe University of New Mexico, Albuquerque, New Mexico ...

    Abstract Linda Butros, Koh Boayue, Prasad MathewThe University of New Mexico, Albuquerque, New Mexico, USAAbstract: Bypassing agents are the mainstay of treatment for patients with hemophilia with high-titer inhibitors. Whereas the availability of these agents has greatly advanced the management of bleeding episodes in this population, timely administration of bypassing agents continues to be hampered by a number of practical limitations, including the need for refrigerated storage of the agent and its reconstitution at room temperature prior to administration, among others. In this review, the importance of early treatment of bleeds and factors that influence this more timely therapeutic approach are highlighted, together with the advantages offered by the use of a new formulation of recombinant activated factor VII that permits improved storage and portability, potentially optimizing timely bypassing agent administration.Keywords: hemophilia, inhibitors, bleeding, treatment, patients, recombinant factor VIIIa
    Keywords Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Therapeutics. Pharmacology ; RM1-950 ; DOAJ:Therapeutics
    Subject code 306
    Language English
    Publishing date 2011-05-01T00:00:00Z
    Publisher Dove Medical Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Leydig cell tumor after treatment for Ewing's sarcoma.

    Butros, Linda J / Phillip, Shaji / Chou, Alexander / Meyers, Paul A / Huvos, Andrew G / Healey, John H / Russo, Paul / Gorlick, Richard G

    Pediatric blood & cancer

    2007  Volume 49, Issue 7, Page(s) 1008–1010

    Abstract: Leydig cell tumors account for 3% of testicular tumors and have never been reported after treatment for Ewing's sarcoma. We report the unusual occurrence of a patient who developed a Leydig cell tumor of the testis 18 years after successful treatment for ...

    Abstract Leydig cell tumors account for 3% of testicular tumors and have never been reported after treatment for Ewing's sarcoma. We report the unusual occurrence of a patient who developed a Leydig cell tumor of the testis 18 years after successful treatment for Ewing's sarcoma. Additional monitoring for second malignancies may become appropriate as long-term survival continues to improve for patients with Ewing's sarcoma.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols ; Bone Neoplasms/diagnosis ; Bone Neoplasms/therapy ; Child ; Combined Modality Therapy ; Follow-Up Studies ; Humans ; Leydig Cell Tumor/diagnosis ; Leydig Cell Tumor/surgery ; Male ; Neoplasms, Second Primary/diagnosis ; Neoplasms, Second Primary/surgery ; Sarcoma, Ewing/diagnosis ; Sarcoma, Ewing/therapy ; Testicular Neoplasms/diagnosis ; Testicular Neoplasms/surgery ; Time ; Treatment Outcome
    Language English
    Publishing date 2007-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.20825
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top