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Article ; Online: Estudio histórico de la Historia Eclesiástica y Civil de Nueva Granada de José Manuel Groot (1800-1878)

Sergio Andrés Mejía Macía

Historia y Sociedad, Iss

2000 Volume 7

Abstract: ... Escrita sobre documentos auténticos, escrita por el bogotano José Manuel Groot, autor de cuadros ...

Abstract	Entre 1869 y 1870 fu publicada en Bogotá la historia eclesiástica y civil de la nueva granada – Escrita sobre documentos auténticos, escrita por el bogotano José Manuel Groot, autor de cuadros de costumbres, pintor, apologista católico y educador. La obra que consta de tres tomos y más de 1800 páginas, constituye toda una batería de guerra dispuesta en contra de las políticas liberales del medio siglo. La escritura del manuscrito progreso durante quince años, durante el periodo en el que se sucedieron algunas de las principales reformas liberales del siglo en el país. La idea de Teodicea antecede a la elaboración historiográfica hecha por Groot y aunque se encuentra latente en toda la obra, en momentos especiales sale a la superficie. La cosmogonía cristiana de Groot, con su noción de la historia como desenvolvimiento del plan divino para el hombre, tomo con sutileza el lugar de las ideas liberales corrientes de un siglo en el que ya era posible escribir historia sin hacer mención de Dios y dio Groot el tinte de un poeta que recurrió al pasado para predicar a sus contemporáneos la necesidad de una regeneración.
Keywords	Historia eclesiástica ; Historia civil ; José Manuel Groot ; Catolicismo ; Liberalismo ; Nueva Granda ; History of scholarship and learning. The humanities ; AZ20-999
Language	English
Publishing date	2000-01-01T00:00:00Z
Publisher	Universidad Nacional de Colombia, sede Medellín
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Understanding the Influence of Socioeconomic Variables on Medicinal Plant Knowledge in the Peruvian Andes.

Corroto, Fernando / Gamarra Torres, Oscar Andrés / Macía, Manuel J

Plants (Basel, Switzerland)

2022 Volume 11, Issue 20

Abstract: In this study, we analyze the impact of 18 socioeconomic factors at individual, family, and locality levels to understand their influence on medicinal plant knowledge (MPK) in four provinces and 12 localities of the northern Andes of Peru. We interviewed ...

Abstract	In this study, we analyze the impact of 18 socioeconomic factors at individual, family, and locality levels to understand their influence on medicinal plant knowledge (MPK) in four provinces and 12 localities of the northern Andes of Peru. We interviewed 50 participants per locality (totaling 600 people) from lowlands and highlands ecoregions. The participants were balanced in terms of generations and gender. We performed multivariate statistical analyses-generalized linear mixed models (GLMMs) and nonmetric multidimensional scaling (NMDS) ordinations-that showed the influence of each socioeconomic variable on the medicinal plant knowledge of people in the different sites. At the individual level, we found that most participants with higher MPK were women, elders, people with lower levels of education and job qualifications, non-migrants, and participants who have lived for a long period in the same region. At the family level, we found that participants living in low economic conditions with few material goods, including their means of transport, tools possession, access to technology, farm size, number of farm animals, and house quality, had higher MPK. At the locality level, we found that people living in more isolated areas with scarce regional services, such as access to paved roads, hospitals, big markets, tourist development, and chlorination of drinking water, had higher MPK. In short, people with less access to modern services and with low economic resources are the main depositaries of MPK. Policy makers and decision makers should consider the significance of MPK in alleviating health problems and diseases in Andean regions, especially for people with rural livelihoods. This local botanical knowledge of medicinal plants should be preserved in the area as a great natural heritage for humanity.
Language	English
Publishing date	2022-10-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants11202681
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Article ; Online: A projected cost-utility analysis of avacopan for the treatment of antineutrophil cytoplasmic antibody-associated vasculitis in Spain.

Macía, Manuel / Díaz-Encarnación, Montserrat / Solans-Laqué, Roser / Mallol, Elisenda Pomares / Castells, Alejandra García / Escribano, Cristina / de Arellano, Antonio Ramírez

Expert review of pharmacoeconomics & outcomes research

2024 Volume 24, Issue 2, Page(s) 227–235

Abstract: Background: Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) are rare autoimmune diseases characterized by inflammation of blood vessels. This study aimed to assess the cost-utility of avacopan in combination with rituximab (RTX) or ... ...

Abstract	Background: Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) are rare autoimmune diseases characterized by inflammation of blood vessels. This study aimed to assess the cost-utility of avacopan in combination with rituximab (RTX) or cyclophosphamide (CYC) compared with glucocorticoids (GC) for the treatment of severe, active AAV in Spain. Methods: A 9-state Markov model was designed to reflect the induction of remission and sustained remission of AAV over a lifetime horizon. Clinical data and utility values were mainly obtained from the ADVOCATE trial, and costs (€ 2022) were sourced from national databases. Quality-adjusted life years (QALYs), and incremental cost-utility ratio (ICUR) were evaluated. An annual discount rate of 3% was applied. Sensitivity analyses were performed to examine the robustness of the results. Results: Avacopan yielded an increase in effectiveness (6.52 vs. 6.17 QALYs) and costs (€16,009) compared to GC, resulting in an ICUR of €45,638 per additional QALY gained. Avacopan was associated with a lower incidence of end-stage renal disease (ESRD), relapse and hospitalization-related adverse events. Sensitivity analyses suggested that the model outputs were robust and that the progression to ESRD was a driver of ICUR. Conclusions: Avacopan is a cost-effective option for patients with severe, active AAV compared to GC in Spain.
MeSH term(s)	Humans ; Antibodies, Antineutrophil Cytoplasmic/therapeutic use ; Cost-Benefit Analysis ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/chemically induced ; Spain ; Remission Induction ; Rituximab ; Glucocorticoids/adverse effects ; Kidney Failure, Chronic ; Aniline Compounds ; Nipecotic Acids
Chemical Substances	Antibodies, Antineutrophil Cytoplasmic ; avacopan (O880NM097T) ; Rituximab (4F4X42SYQ6) ; Glucocorticoids ; Aniline Compounds ; Nipecotic Acids
Language	English
Publishing date	2024-01-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2208481-2
ISSN	1744-8379 ; 1473-7167
ISSN (online)	1744-8379
ISSN	1473-7167
DOI	10.1080/14737167.2023.2297790
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Article ; Online: The species of Eilema Hübner, [1819] sensu lato present in Europe and North Africa (Lepidoptera: Erebidae: Arctiinae: Lithosiini).

Macià, Ramon / Ylla, Josep / Gastón, Javier / Huertas, Manuel / Bau, Josep

Zootaxa

2022 Volume 5191, Issue 1, Page(s) 1–87

Abstract: The species of Eilema Hübner, [1819] sensu lato, present in Europe and North Africa, are studied on the basis of morphological characteristics and molecular genetics. Images of adults, genitalia of both sexes, immature stages, as well as phylogenetic ... ...

Abstract	The species of Eilema Hübner, [1819] sensu lato, present in Europe and North Africa, are studied on the basis of morphological characteristics and molecular genetics. Images of adults, genitalia of both sexes, immature stages, as well as phylogenetic trees obtained from the combined analysis of three different genetic markers are presented. Data on life cycles, food plants, and geographic distribution are also included. The morphological differences observed within Eilema sensu lato have led the authors to create the genera Indalia gen. nov. and Pseudokatha gen. nov. New combinations are stablished: Manulea iberica (Mentzer, 1980) st. rest., comb. nov.; Indalia marcida (Mann, 1859) comb. nov.; Indalia predotae (Schawerda, 1927) comb. nov.; Indalia albicosta (Rogenhofer, 1894) comb. nov.; Indalia interposita (Rothschild, 1914) comb. nov.; Indalia uniola (Rambur, [1866]) comb. nov.; Indalia lutarella (Linnaeus, 1758) comb. nov.; Indalia pygmaeola (Doubleday, 1847) comb. nov.; Pseudokatha rungsi (Toulgoët, 1960) comb. nov., and Eilema albicosta witti Kobes, 1993 syn. nov.
MeSH term(s)	Female ; Male ; Animals ; Phylogeny ; Moths ; Africa, Northern ; Europe ; Genitalia
Language	English
Publishing date	2022-10-03
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5191.1.1
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Article: What Is the Most Efficient Methodology for Gathering Ethnobotanical Data and for Participant Selection? Medicinal Plants as a Case Study in the Peruvian Andes

Corroto, Fernando / Macía, Manuel J

Economic botany. 2021 Mar., v. 75, no. 1

2021

Abstract: What Is the Most Efficient Methodology for Gathering Ethnobotanical Data and for Participant Selection? Medicinal Plants as a Case Study in the Peruvian Andes. The loss of traditional knowledge (TK) invariably continues worldwide and there is an urgent ... ...

Abstract	What Is the Most Efficient Methodology for Gathering Ethnobotanical Data and for Participant Selection? Medicinal Plants as a Case Study in the Peruvian Andes. The loss of traditional knowledge (TK) invariably continues worldwide and there is an urgent need to document and safeguard it before it vanishes. Researchers need efficient methods to document TK, taking fieldwork time and costs into account. In this study, we focused on medicinal plants to compare (1) the information provided by 600 expert and general participants from 12 localities in northern Peruvian Andes; and (2) the information gathered in semi–structured and structured interviews with 81 informants at two localities in the same area. We found that expert informants reported 91% of medicinal species and 67% of medicinal indications in less than half the time than was required to gather information from general informants. Using structured interviews yielded an increase of 18% of medicinal species and 21% of medicinal indications, but the time spent interviewing was 100% higher than in the semi–structured interviews. Overall, since time and costs are key factors often limiting ethnobotanical research, we suggest focusing on interviews with expert informants to gain efficiency. Regarding the interview method, the most efficient use of structured interviews would be in the cases or areas where (some) ethnobotanical data have been reported previously. If a researcher starts a new project and little or no previous TK data exist for a given area, we would recommend the use of semi–structured interviews. However, the available time and budget will always be key factors to be taken into account in order to select the best methodology of any TK study.
Keywords	case studies ; ethnobotany ; indigenous knowledge ; researchers ; Andes region
Language	English
Dates of publication	2021-03
Size	p. 63-75.
Publishing place	Springer US
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	419272-2
ISSN	1874-9364 ; 0013-0001
ISSN (online)	1874-9364
ISSN	0013-0001
DOI	10.1007/s12231-021-09514-7
Database	NAL-Catalogue (AGRICOLA)

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Article: Medicinal Plants for Rich People vs. Medicinal Plants for Poor People: A Case Study from the Peruvian Andes.

Corroto, Fernando / Rascón, Jesús / Barboza, Elgar / Macía, Manuel J

Plants (Basel, Switzerland)

2021 Volume 10, Issue 8

Abstract: Traditional knowledge (TK) of medicinal plants in cities has been poorly studied across different inhabitants' socioeconomic sectors. We studied the small city of Chachapoyas (~34,000 inhabitants) in the northern Peruvian Andes. We divided the city into ... ...

Abstract	Traditional knowledge (TK) of medicinal plants in cities has been poorly studied across different inhabitants' socioeconomic sectors. We studied the small city of Chachapoyas (~34,000 inhabitants) in the northern Peruvian Andes. We divided the city into three areas according to the socio-economic characteristics of its inhabitants: city center (high), intermediate area (medium), and city periphery (low). We gathered information with 450 participants through semi-structured interviews. Participants of the city periphery showed a higher TK of medicinal plants than participants of the intermediate area, and the latter showed a higher TK than participants of the city center. The acquisition of medicinal plants was mainly through their purchase in markets across the three areas, although it was particularly relevant in the city center (94%). Participants of all socioeconomic levels widely used the same medicinal plants for similar purposes in Chachapoyas, which is likely based on a common Andean culture that unites their TK. However, participants with the lowest socioeconomic level knew and used more plants for different medicinal uses, indicating the necessity of these plants for their livelihoods. City markets with specialized stores that commercialize medicinal plants are key to preserve the good health of poor and rich people living in Andean cities and societies.
Language	English
Publishing date	2021-08-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants10081634
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Article: Electronic Patient-Reported Outcomes in Nephrology: Focus on Hemodialysis.

Pérez-Morales, Rosa / Buades-Fuster, Juan Manuel / Esteve-Simó, Vicent / Macía-Heras, Manuel / Mora-Fernández, Carmen / Navarro-González, Juan F

Journal of clinical medicine

2022 Volume 11, Issue 3

Abstract: The success of hemodialysis (HD) treatments has been evaluated using objective measures of analytical parameters, or machine-measured parameters, despite having available validated instruments that assess patient perspective. There is an emerging ... ...

Abstract	The success of hemodialysis (HD) treatments has been evaluated using objective measures of analytical parameters, or machine-measured parameters, despite having available validated instruments that assess patient perspective. There is an emerging interest regarding the use and relevance of patient-related outcomes (PROs). Electronic PROs (ePROs) involve the use of electronic technology, provide rapid access to this information, and are becoming more widely used in clinical trials and studies to evaluate efficacy and safety. Despite the scarce literature, this review suggests that ePROs are useful in providing a more customized and multidimensional approach to patient management and in making better clinical decisions in relevant aspects such as vascular access, duration and frequency of dialysis sessions, treatment of anemia, mental health, fatigue, and quality of life. The purpose of this review is to raise interest in the systematic use of ePROs in HD and to promote the development of studies in this field, which can respond to the gaps in knowledge and contribute to the implementation of the use of ePROs through new technologies, helping to improve the quality of health care.
Language	English
Publishing date	2022-02-07
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11030861
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Article ; Online: Prediction and Analysis of Heart Failure Decompensation Events Based on Telemonitored Data and Artificial Intelligence Methods.

Kerexeta, Jon / Larburu, Nekane / Escolar, Vanessa / Lozano-Bahamonde, Ainara / Macía, Iván / Beristain Iraola, Andoni / Graña, Manuel

Journal of cardiovascular development and disease

2023 Volume 10, Issue 2

Abstract: Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Heart failure (HF) occurs when the heart is not able to pump enough blood to satisfy metabolic needs. People diagnosed with chronic HF may ... ...

Abstract	Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Heart failure (HF) occurs when the heart is not able to pump enough blood to satisfy metabolic needs. People diagnosed with chronic HF may suffer from cardiac decompensation events (CDEs), which cause patients' worsening. Being able to intervene before decompensation occurs is the major challenge addressed in this study. The aim of this study is to exploit available patient data to develop an artificial intelligence (AI) model capable of predicting the risk of CDEs timely and accurately. Materials and Methods: The vital variables of patients (n = 488) diagnosed with chronic heart failure were monitored between 2014 and 2022. Several supervised classification models were trained with these monitoring data to predict CDEs, using clinicians' annotations as the gold standard. Feature extraction methods were applied to identify significant variables. Results: The XGBoost classifier achieved an AUC of 0.72 in the cross-validation process and 0.69 in the testing set. The most predictive physiological variables for CAE decompensations are weight gain, oxygen saturation in the final days, and heart rate. Additionally, the answers to questionnaires on wellbeing, orthopnoea, and ankles are strongly significant predictors.
Language	English
Publishing date	2023-01-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2777082-5
ISSN	2308-3425 ; 2308-3425
ISSN (online)	2308-3425
ISSN	2308-3425
DOI	10.3390/jcdd10020048
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Article ; Online: Reflections on the need for Nephropathology Reference Units.

Salgueira Lazo, Mercedes / Macía Heras, Manuel / Del Pino Pino, M Dolores / Palacios Calvo, José

Nefrologia

2021 Volume 41, Issue 1, Page(s) 15–16

Language	English
Publishing date	2021-03-09
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2020.04.007
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Article ; Online: Different patterns in medicinal plant use along an elevational gradient in northern Peruvian Andes.

Corroto, Fernando / Gamarra Torres, Oscar A / Macía, Manuel J

Journal of ethnopharmacology

2019 Volume 239, Page(s) 111924

Abstract: Ethnopharmacological relevance: Through the study of mestizo people that share a common culture in a large geographic region and where traditional knowledge (TK) is still poorly documented, we compared medicinal plant use in the northern Andes of Peru.!# ...

Abstract	Ethnopharmacological relevance: Through the study of mestizo people that share a common culture in a large geographic region and where traditional knowledge (TK) is still poorly documented, we compared medicinal plant use in the northern Andes of Peru. Aims of the study: (1) To compare patterns of the distribution of TK for a human group living between two ecoregions: high tropical montane forests vs. low tropical montane forests; (2) to understand the TK at the gender level; and (3) to analyse TK transmission over five generations. Material and methods: The study was conducted in two ecoregions, four areas and 12 localities. We gathered information with 600 participants through semi-structured interviews. We worked with 3-7 expert informants per locality using the "walk in the woods" methodology for gathering ethnomedicinal information in the field. We annotated local vernacular names, medicinal indications, and collected the plants in their habitats. Then we interviewed the rest of the participants in their homes. To evaluate significant differences between highlands and lowlands, we use general mixed linear models test and its corresponding post hoc LSD Fisher test of multiple comparisons (p < 0.05) at ecoregion, gender and generation level. Results: A total of 416 species belonging to 107 plant families and 13,898 use-reports were found in both ecoregions. Overall, significant differences indicated that people in the highlands had higher TK than people in the lowlands for most of the medicinal categories. Women showed higher knowledge on medicinal plants in all medicinal categories and areas in both ecoregions. However, transmission of TK showed different patterns between ecoregions. In the highlands, the TK increased from the youngest to the senior group (51-60 years), with a slight decreasing for those over 60 years, whereas in the lowlands the findings were less clear and generations with highest TK were divergent across localities. Conclusion: TK on medicinal plants is still widely applied in the tropical montane forests of northern Peru. The localities with less prosperous socioeconomic development (highlands) were the areas with higher TK on medicinal plants. Women are mainly the depositories of the traditional medicine. The older generations maintain most of the TK in the highlands, whereas in the lowlands the TK is more widespread across generations. Future conservation programs on medicinal plants should understand who are the generations depositaries of the TK before dedicate any effort.
MeSH term(s)	Adolescent ; Adult ; Altitude ; Female ; Forests ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Medicine, Traditional ; Middle Aged ; Peru ; Phytotherapy ; Plants, Medicinal ; Young Adult
Language	English
Publishing date	2019-04-28
Publishing country	Ireland
Document type	Comparative Study ; Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2019.111924
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