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Article ; Online: Two vicious circles associated with the aging of the immune system in the development of severe forms of COVID-19.

Vrbic, Miodrag / Milinkovic, Ana

2023 Volume 4, Page(s) 1260053

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-09-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	3076785-4
ISSN	2673-6217 ; 2673-6217
ISSN (online)	2673-6217
ISSN	2673-6217
DOI	10.3389/fragi.2023.1260053
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Article: Porphyromonas Gingivalis in Different Peri-Implant Conditions: a Pilot Cross - Sectional Study.

Savčić, Nikolija / Henjaš, Damir / Jezdić, Marija / Đinić Krasavčević, Ana / Milinković, Iva

Acta stomatologica Croatica

2023 Volume 56, Issue 4, Page(s) 387–394

Abstract: Objective: To assess the potential correlation between clinical peri-implant parameters and the presence of : Material and methods: The study included 30 patients from the Department of Periodontology and Oral Medicine divided into three equal groups, ...

Abstract	Objective: To assess the potential correlation between clinical peri-implant parameters and the presence of Material and methods: The study included 30 patients from the Department of Periodontology and Oral Medicine divided into three equal groups, defined according to the following diagnoses: peri-implantitis (PI), peri-implant mucositis (PM), and peri-implant health (HI). Clinical parameters such as peri-implant probing depth (PPD), bleeding on probing (BOP), suppuration on probing (SUP), and plaque index (PI) were recorded. The samples of peri-implant crevicular fluid were collected and relative levels of Results: The mean patient age was 51.33 ± 12.61 years. The mean value for Conclusions: The findings of this research indicate higher relative levels of
Language	English
Publishing date	2023-01-24
Publishing country	Croatia
Document type	Journal Article
ZDB-ID	603047-6
ISSN	0001-7019
ISSN	0001-7019
DOI	10.15644/asc56/4/5
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Zs.B 1367: Show issues

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Article ; Online: How do open coastal fire episodes' impact sea surface microlayer neuston communities?

Tomaš, Ana Vrdoljak / Šantić, Danijela / Šolić, Mladen / Skejić, Sanda / Milinković, Andrea / Kušan, Ana Cvitešić / Gašparović, Blaženka / Šestanović, Stefanija / Frka, Sanja

The Science of the total environment

2022 , Page(s) 160593

Abstract: Human-induced climate change is expected to increase the frequency and severity of vegetation fires. The Mediterranean region is considered particularly prone to fire episodes in summer. It is well known that pyrogenic particles are an important source ... ...

Abstract	Human-induced climate change is expected to increase the frequency and severity of vegetation fires. The Mediterranean region is considered particularly prone to fire episodes in summer. It is well known that pyrogenic particles are an important source of external nutrients for the marine environment, especially in oligotrophic areas. In this study, the plankton components of the sea surface layers were integrated to evaluate, for the first time, their dynamics over six months and their response to fire events in a typical coastal area of the Adriatic Sea. Concentrations of nutrients and organic compounds, together with plankton communities were significantly higher in the sea surface microlayer (SML, <1 mm thick), than in the underlying water from 1 m depth. The piconeuston community and chlorophyll a responded with extreme abundance and concentration to the most intense fire event that enriched the SML with NH
Language	English
Publishing date	2022-12-02
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.160593
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Article ; Online: Depression is associated with poor self-reported adherence to antiretroviral therapy among people living with HIV attending an HIV clinic in the UK: results from a cross-sectional study.

Paredes, Jose Luis / Arenas-Pinto, Alejandro / McAlpine, Connor / Matthews, Rebecca / Milinkovic, Ana / Suonpera, Emmi

AIDS care

2024 , Page(s) 1–8

Abstract: Contemporary evidence is needed to assess whether the prevalence of depression remains high among people living with HIV in the United Kingdom despite recent efforts to improve patients' mental health, and if depression is negatively associated with ... ...

Abstract	Contemporary evidence is needed to assess whether the prevalence of depression remains high among people living with HIV in the United Kingdom despite recent efforts to improve patients' mental health, and if depression is negatively associated with individuals' adherence to antiretroviral therapy. In a secondary analysis of a cross-sectional clinic-based survey of alcohol consumption and associated health behaviour among people living with HIV in London, of the 221 respondents, 106 (48%) had poor self-reported adherence to antiretroviral therapy (CASE Index) and 69 (31%) screened positive for depression (PHQ-9). Poor self-reported adherence to ART was 72% higher among participants who screened positive for depression in comparison with participants who screened negative. Respondents who were younger, unemployed, and reported problematic drug use were more likely to screen positive for depression. Screening and management of depression as a part of routine HIV care may support adherence to antiretroviral therapy.
Language	English
Publishing date	2024-01-30
Publishing country	England
Document type	Journal Article
ZDB-ID	1012651-x
ISSN	1360-0451 ; 0954-0121
ISSN (online)	1360-0451
ISSN	0954-0121
DOI	10.1080/09540121.2024.2303969
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Article ; Online: Results of a Multi-Disciplinary Approach Involving Geriatricians of a Clinic for Older People Living with HIV.

Ates, Aylin Cansu / Bachnak, Andrei / Murateva, Yana / Toiber Kent, Yarden / Blackburn, Sophie / Boffito, Marta / Milinkovic, Ana / Tong, Tim / Varadarajan, Maithili

AIDS patient care and STDs

2023 Volume 37, Issue 5, Page(s) 213–214

MeSH term(s)	Humans ; Aged ; Geriatricians ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Ambulatory Care Facilities
Language	English
Publishing date	2023-04-20
Publishing country	United States
Document type	Letter
ZDB-ID	1326868-5
ISSN	1557-7449 ; 0893-5068 ; 1087-2914
ISSN (online)	1557-7449
ISSN	0893-5068 ; 1087-2914
DOI	10.1089/apc.2023.0011
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Zs.A 2328: Show issues

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Article ; Online: Multi-tablet, Single-Tablet, or Long-Acting Antiretroviral Treatment for HIV: A Cross-sectional Study of Patient Preferences in the United States and Spain.

Carracedo, Alfredo Soler / Oliveira, Vitor / Saz, Jorge / Pujol, Ferran / Milinkovic, Ana / Webel, Allison

The Journal of the Association of Nurses in AIDS Care : JANAC

2022 Volume 33, Issue 6, Page(s) 638–645

MeSH term(s)	Humans ; United States ; Cross-Sectional Studies ; Spain ; HIV Infections/drug therapy ; Patient Preference ; Anti-Retroviral Agents/therapeutic use ; Anti-HIV Agents/therapeutic use ; Tablets/therapeutic use
Chemical Substances	Anti-Retroviral Agents ; Anti-HIV Agents ; Tablets
Language	English
Publishing date	2022-06-07
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1159376-3
ISSN	1552-6917 ; 1055-3290
ISSN (online)	1552-6917
ISSN	1055-3290
DOI	10.1097/JNC.0000000000000343
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Article ; Online: Correlation between different equations to calculate free testosterone for improved detection of hypogonadism in people living with HIV.

Wu, Shuang / Hilton, Orla / Pereira, Branca / Girometti, Nicolo / Milinkovic, Ana / Ollandini, Giangiacomo / Boffito, Marta

International journal of STD & AIDS

2022 Volume 33, Issue 6, Page(s) 613–617

Abstract: The diagnosis of hypogonadism in people living with HIV (PLWH) remains challenging by the lack of a standardised diagnostic algorithm. Since sexual hormone-binding globulin levels are commonly increased in PLWH, guidelines recommend assessing free ... ...

Abstract	The diagnosis of hypogonadism in people living with HIV (PLWH) remains challenging by the lack of a standardised diagnostic algorithm. Since sexual hormone-binding globulin levels are commonly increased in PLWH, guidelines recommend assessing free testosterone (FT) along with total testosterone levels. We compared different online equations available to estimate FT levels and found a good correlation amongst all algorithms. Estimating FT levels increased diagnostic accuracy of hypogonadism and therefore should be encouraged in clinical practice in PLWH with clinical symptoms of hypogonadism, even when total testosterone levels are normal.
MeSH term(s)	HIV Infections/complications ; Humans ; Hypogonadism/diagnosis ; Hypogonadism/drug therapy ; Testosterone/blood
Chemical Substances	Testosterone (3XMK78S47O)
Language	English
Publishing date	2022-04-04
Publishing country	England
Document type	Journal Article
ZDB-ID	1018089-8
ISSN	1758-1052 ; 0956-4624
ISSN (online)	1758-1052
ISSN	0956-4624
DOI	10.1177/09564624221083760
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Article: HIV-associated lipodystrophy syndrome.

Milinković, Ana

Collegium antropologicum

2006 Volume 30 Suppl 2, Page(s) 59–62

Abstract: In recent years, lipodystrophy and its related complications have become one of the major problems confronting HIV-infected patients on antiretroviral therapy. More than ten years after having been described for the first time, comprehensive knowledge of ...

Abstract	In recent years, lipodystrophy and its related complications have become one of the major problems confronting HIV-infected patients on antiretroviral therapy. More than ten years after having been described for the first time, comprehensive knowledge of its underlying molecular basis, the natural history of body fat changes and metabolic abnormalities, and even a working definition of lipodystrophy are all still lacking. No standardized objective assessment of body fat has been incorporated into clinical practice for patient monitoring. Although a huge amount of data has been generated, no clinically proven treatment for any feature of lipodystrophy is currently available. The only intervention that has been shown to reverse lipoatrophy had been the discontinuation of thymidine analogues, although even then the results obtained are at most partial or modest. Recently published studies using uridine (NucleomaxX) and pravastatin resulted in a significant increase of subcutaneous fat. The potential for reversing lipodystrophy once it has developed is limited, but promising results in preventing it are obtained with thymidine analogue-sparing initial antiretroviral regimens. These results raise the question of whether we may be facing a definitive solution to the lipodystrophy syndrome.
MeSH term(s)	Antiretroviral Therapy, Highly Active/adverse effects ; HIV Infections/drug therapy ; HIV-Associated Lipodystrophy Syndrome/diagnosis ; HIV-Associated Lipodystrophy Syndrome/etiology ; HIV-Associated Lipodystrophy Syndrome/therapy ; Humans ; Multicenter Studies as Topic ; Risk Factors
Language	English
Publishing date	2006-12
Publishing country	Croatia
Document type	Journal Article
ZDB-ID	233430-6
ISSN	0350-6134 ; 0353-3735
ISSN	0350-6134 ; 0353-3735
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Article: Variabilities of biochemical properties of the sea surface microlayer: Insights to the atmospheric deposition impacts

Milinković, Andrea / Penezić, Abra / Kušan, Ana Cvitešić / Gluščić, Valentina / Žužul, Silva / Skejić, Sanda / Šantić, Danijela / Godec, Ranka / Pehnec, Gordana / Omanović, Dario / Engel, Anja / Frka, Sanja

Science of the total environment. 2022 Sept. 10, v. 838

2022

Abstract: Atmospheric deposition (AD) of nutrients and its impact on the sea surface requires consideration of interfacial processes within the sea surface microlayer (SML), the ocean-atmosphere boundary layer of major importance for many global biogeochemical and ...

Abstract	Atmospheric deposition (AD) of nutrients and its impact on the sea surface requires consideration of interfacial processes within the sea surface microlayer (SML), the ocean-atmosphere boundary layer of major importance for many global biogeochemical and climate-related processes. This study comprised a comprehensive dataset, including dissolved NO₃⁻, NH₄⁺ and PO₄³⁻ in ambient aerosol particles, wet deposition and sea surface samples collected from February to July 2019 at a central Adriatic coastal site. The aerosol mean concentration of dissolved nitrogen (DIN = NO₃⁻ + NH₄⁺) and PO₄³⁻ were 48.8 ± 82.8 μmol m⁻³ and 0.8 ± 0.6 μmol m⁻³, respectively, while their total fluxes (dry + wet) ranged from 24.2 to 212.3 μmol m⁻² d⁻¹ (mean 123.2 ± 53.2 μmol m⁻² d⁻¹) and from 1.2 to 2.1 μmol m⁻² d⁻¹ (mean 1.5 ± 0.3 μmol m⁻² d⁻¹), respectively. Intensive local episodes of open biomass burning (BB) significantly increased aerosol DIN concentrations as well as DIN deposition fluxes, particularly altering the molar DIN/PO₄³⁻ ratio of atmospheric samples. The DIN temporal patterns showed high variability in the SML (range 0.2–24.6 μmol L⁻¹, mean 5.0 ± 7.1 μmol L⁻¹) in contrast to the underlying water samples (range 0.5–4.2 μmol L⁻¹, mean 1.9 ± 1.2 μmol L⁻¹), with significant increases during BB periods. Variability in abundance of heterotrophic bacteria and autotrophs in the SML along with concentrations of bulk dissolved and particulate organic carbon as well as dissolved and particulate lipids and carbohydrates, gel particles and surfactants followed DIN enhancements with a two-week delay. This study showed that AD can affect the short-term scale enrichments of organic matter in the SML, especially when accompanied by BB emissions typical of the overall Mediterranean coastal environment. This could have strong implications for global air-sea exchange processes, including those of climate relevant gases, mediated by the SML.
Keywords	aerosols ; autotrophs ; biomass ; climate ; data collection ; environment ; gels ; nitrogen ; particulate organic carbon ; wet deposition
Language	English
Dates of publication	2022-0910
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.156440
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Immunohistochemical analysis of soft tissue response to polyetheretherketone (PEEK) and titanium healing abutments on dental implants: a randomized pilot clinical study.

Milinkovic, Iva / Krasavcevic, Ana Djinic / Jankovic, Sasha / Sopta, Jelena / Aleksic, Zoran

BMC oral health

2022 Volume 22, Issue 1, Page(s) 484

Abstract: Background: The data on polyetheretherketone (PEEK) influence on the peri-implant soft tissues in clinical settings are deficient. The aims of this pilot study were to analyze and compare soft tissues' response to PEEK and titanium (Ti) healing ... ...

Abstract	Background: The data on polyetheretherketone (PEEK) influence on the peri-implant soft tissues in clinical settings are deficient. The aims of this pilot study were to analyze and compare soft tissues' response to PEEK and titanium (Ti) healing abutments (HA) by means of histological and immunohistochemical analyses. Methods: A total of 22 implants with PEEK or Ti HA were placed in 11 patients, applying the "split-mouth" study design. Three months later, soft tissue specimens were harvested from 20 implants for histology in order to qualitatively detect the inflammatory cells' presence, to semi-qualitatively analyze the inflammation intensity and to assess the inflammatory responses type by immunohistochemical analysis using LCA, CD3, CD20 and CD68 antibodies. Results: Epithelial infiltrate followed by an intensive inflammation in sub-epithelium was observed in 100% around PEEK HA. A number of LCA+ and CD 68+ cells was significantly higher in PEEK comparing to Ti group (p = 0.001 and p = 0.020, respectively), while CD 20+ and CD3+ counted cells were found in a significantly higher amount in Ti than in PEEK group (p = 0.006 and p = 0.010, respectively). Conclusion: PEEK HA seems to evoke the more intense tissue inflammatory response demonstrated predominantly by histocytes' and plasmacytes' activation, while Ti HA triggers the inflammatory reaction of lower intensity, dominantly mediated by B-cells. Trial registration: The study registered at ClinicalTrials.gov (NCT04436939).
MeSH term(s)	Humans ; Dental Implants/adverse effects ; Titanium ; Pilot Projects ; Dental Abutments ; Ketones ; Polyethylene Glycols ; Inflammation
Chemical Substances	Dental Implants ; polyetheretherketone (31694-16-3) ; Titanium (D1JT611TNE) ; Ketones ; Polyethylene Glycols (3WJQ0SDW1A)
Language	English
Publishing date	2022-11-11
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-022-02536-0
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