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Book ; Online ; E-Book: Cities and Mega Risks

Khan, Mohammad Aslam

COVID-19 and Climate Change

2022

Abstract: This book focuses on the emergence of COVID-19 and climate change as twin mega risks to cities of both developed and developing countries. The work analyses how the pandemic has transformed city functions, promoted remote working, and affected ... ...

Author's details	by Mohammad Aslam Khan
Abstract	This book focuses on the emergence of COVID-19 and climate change as twin mega risks to cities of both developed and developing countries. The work analyses how the pandemic has transformed city functions, promoted remote working, and affected socializing, education and learning patterns, recreation, as well as shopping and entertainment. It discusses the lessons learned from these two Mega Risks, the evolution of urban patterns and functions in their wake, and provides visionary thinking for the improvement of cities from the experiences gained. The COVID-19 Pandemic and climate change are both posing serious threats to cities’ future. Together, they demand changes in the ways cities’ function and operate. The work presents a case for a better understanding of the twin mega risks, the magnitude of their impacts, the responses of cities in combating these issues, and planning strategies for preparing, mitigating and adapting to these and future risks. The book is designed to provide reliable resource materials for a wide audience such as planners, professional practitioners, scientists, students, teachers and researchers working in various fields including geography, environmental sciences, social sciences, policy and planning.
Keywords	Sustainability ; Urban economics ; Public health ; Urban Economics ; Public Health
Subject code	737
Language	English
Size	1 online resource (360 pages)
Edition	1st ed. 2022.
Publisher	Springer International Publishing ; Imprint: Springer
Publishing place	Cham
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	9783031140884 ; 9783031140877 ; 3031140885 ; 3031140877
DOI	10.1007/978-3-031-14088-4
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online ; E-Book: Advances in electronic materials for clean energy conversion and storage applications

Khan, Aftab Aslam Parwaz / Nazim, Mohammed / Asiri, Abdullah M.

(Woodhead Publishing Series in Electronic and Optical Materials)

2023

Abstract: Advances in Electronic Materials for Clean Energy Conversion and Storage Applications reviews green synthesis and fabrication techniques of various electronic materials and their derivatives for applications in photovoltaics. The book investigates recent ...

Author's details	edited by Aftab Aslam Parwaz Khan, Mohammed Nazim, and Abdullah M. Asiri
Series title	Woodhead Publishing Series in Electronic and Optical Materials
Abstract	Advances in Electronic Materials for Clean Energy Conversion and Storage Applications reviews green synthesis and fabrication techniques of various electronic materials and their derivatives for applications in photovoltaics. The book investigates recent advances, progress and issues of photovoltaic-based research, including organic, hybrid, dye-sensitized, polymer, and quantum dot-based solar cells. There is a focus on applications for clean energy and storage in the book. Clean energy is defined as energy derived from renewable resources or zero-emission sources and natural processes that are regenerative and sustainable resources such as biomass, geothermal energy, hydropower, solar and wind energy. Materials discussed include nanomaterials, nanocomposites, polymers, and polymer-composites. Advances in clean energy conversion and energy storage devices are also reviewed thoroughly based on recent research and developments such as supercapacitors, batteries etc. Reliable methods to characterize and analyze these materials systems and devices are emphasized throughout the book. Important information on synthesis and analytical chemistry of these important systems are reviewed, but also material science methods to investigate optical properties of carbon-nanomaterials, metal oxide nanomaterials and their nanocomposites.
Keywords	Electronics/Materials ; Clean energy ; Energy conversion ; Energy storage
Subject code	621.381
Language	English
Size	1 online resource (606 pages)
Publisher	Elsevier
Publishing place	Amsterdam, Netherlands
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	9780323914475 ; 9780323912068 ; 0323914470 ; 0323912060
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online ; E-Book: Microbes for sustainable insect pest management / Volume 1

Khan, Md. Aslam / Ahmad, Wasim

an eco-friendly approach

(Sustainability in plant and crop protection)

2019

Author's details	Md. Aslam Khan, Wasim Ahmad, editors
Series title	Sustainability in plant and crop protection Microbes for sustainable insect pest management
Collection	Microbes for sustainable insect pest management
Language	English
Size	1 Online-Ressource (X, 396 Seiten), Illustrationen
Publishing country	Switzerland
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020231340
ISBN	978-3-030-23045-6 ; 9783030230449 ; 3-030-23045-7 ; 3030230449
DOI	10.1007/978-3-030-23045-6
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Microbes for sustainable insect pest management

Khan, Md. Aslam / Ahmad, Wasim

an eco-friendly approach

(Sustainability in plant and crop protection)

2019

Author's details	Md. Aslam Khan, Wasim Ahmad, editors
Series title	Sustainability in plant and crop protection
Keywords	Entomology ; Agriculture ; Soil conservation
Subject code	595.7
Language	English
Dates of publication	2019-9999
Publisher	Springer International Publishing ; Imprint: Springer
Publishing place	Cham
Publishing country	Switzerland
Document type	Book ; Online
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020231329
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: The Use of CRISPR-Cas9 Genetic Technology in Cardiovascular Disease: A Comprehensive Review of Current Progress and Future Prospective.

Asif, Muhammad / Khan, Wahab J / Aslam, Sadia / Aslam, Awais / Chowdhury, Mohammed A

Cureus

2024 Volume 16, Issue 4, Page(s) e57869

Abstract: Over the last century, there have been major landmark developments in the field of medicine, enabling us to control and cure various diseases on a larger scale. A few of these include the discovery of antibiotics, the development of vaccines, and the ... ...

Abstract	Over the last century, there have been major landmark developments in the field of medicine, enabling us to control and cure various diseases on a larger scale. A few of these include the discovery of antibiotics, the development of vaccines, and the origin of organ and tissue transplants. The continued quest for innovation in microbiology and medicine has helped humankind save millions of lives and decrease morbidity at the global level. Genetic medicine has grown significantly in the last two decades and appears to be the next frontier of curative therapies for chronic diseases. One important landmark in genetic medicine is the development of CRISPR (clustered, regularly interspaced short palindromic repeats) technology. In this article, we describe the basic structure and function of the CRISPR-Cas9 system, which, simply put, consists of an RNA part and a protein. It works as a molecular scissor that can perform targeted cuts followed by repairs in and around the genes of interest to attain favorable translational outcomes. We focused on summarizing recent studies using CRISPR-Cas9 technology in diagnosing and treating cardiovascular disease. These studies are primarily experimental and limited to animal models. However, their results are promising enough to anticipate that this technology will undoubtedly be available in clinical medicine in the coming years. CRISPR-Cas9-mediated gene editing has been used to study and potentially treat congenital heart disease, hyperlipidemias, arrhythmogenic cardiomyopathies, and the prevention of ischemia-reperfusion injury. Despite the current progress, we recognize the several challenges this technology faces, including funding for research, improving precision and reproducible results for human subjects, and establishing protocols for ethical compliance so that it is acceptable to the scientific community and the general public.
Language	English
Publishing date	2024-04-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.57869
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Risk analysis and seroprevalence of bovine ephemeral fever virus in Punjab, Pakistan.

Nadeem, Shahid / Aslam, Rizwan / Sajjad-Ur-Rahman / Khan, Muhammad Kasib

Veterinarni medicina

2024 Volume 69, Issue 3, Page(s) 67–76

Abstract: Bovine ephemeral fever (BEF) is a vector-borne viral disease caused by the RNA virus which belongs to the ... ...

Abstract	Bovine ephemeral fever (BEF) is a vector-borne viral disease caused by the RNA virus which belongs to the genus
Language	English
Publishing date	2024-03-26
Publishing country	Czech Republic
Document type	Journal Article
ZDB-ID	412227-6
ISSN	0375-8427 ; 0590-5214
ISSN	0375-8427 ; 0590-5214
DOI	10.17221/95/2023-VETMED
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Article: Frequency of Retinopathy in Patients Newly Diagnosed With Type 2 Diabetes Mellitus.

Khan, Wagmah Javed / Aslam, Tahir

Cureus

2023 Volume 15, Issue 3, Page(s) e36513

Abstract: Background: The most prevalent microvascular consequence of diabetes mellitus on the eye is diabetic retinopathy, which is also one of the major reasons for poor vision in the working-age population. The objective of this study was to estimate the ... ...

Abstract	Background: The most prevalent microvascular consequence of diabetes mellitus on the eye is diabetic retinopathy, which is also one of the major reasons for poor vision in the working-age population. The objective of this study was to estimate the prevalence of type 2 diabetic retinopathy in participants. Methods: The Department of Medicine at the Hayatabad Medical Complex in Peshawar performed a six-month cross-sectional study from May to November 2022. A total of 196 patients with type 2 diabetes mellitus were included in the research. Results: Ages ranged from 18 to 60 years with a mean age of 37.59 ± 10.21 years, with the majority of the patients (n=16) belonging to the fourth decade. Thirty-one individuals (15.81%) with clinically diagnosed type 2 diabetes mellitus had diabetic retinopathy, of which 12 (6.12%) were females and 19 (9.69%) were males. Among patients with diabetic retinopathy, glycated haemoglobin (HbA1C) was determined to be 9.4 ± 1.5, and among those with other types of retinopathy, background retinopathy was detected in 11 (5.61%) men and seven (3.57%) female patients. Conclusion: The majority of diabetic retinopathy patients in the current study were older than 40 years and were primarily males. In newly diagnosed type 2 diabetes mellitus participants, retinopathy occurred in 15.81% of cases (n=31), with background retinopathy accounting for the majority of cases (n=18, 9.18%).
Language	English
Publishing date	2023-03-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.36513
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of qSOFA Score, SIRS Criteria, and SOFA Score as predictors of mortality in patients with sepsis.

Khan, A M / Aslam, Shaikh M

Ghana medical journal

2023 Volume 56, Issue 3, Page(s) 191–197

Abstract: Objectives: Early diagnosis and treatment of sepsis are associated with a better outcome. With the change in the definition of sepsis, SOFA score and qSOFA score (heart rate, systolic blood pressure and Glasgow coma scale) were introduced and SIRS ... ...

Abstract	Objectives: Early diagnosis and treatment of sepsis are associated with a better outcome. With the change in the definition of sepsis, SOFA score and qSOFA score (heart rate, systolic blood pressure and Glasgow coma scale) were introduced and SIRS criteria were removed. This study compared the qSOFA score, SIRS criteria and SOFA score as predictors of mortality in patients with sepsis. Design: Prospective observational study. Setting: Department of General Medicine of a tertiary hospital. Participants: The study included 116 patients. Interventions: SOFA scores (range, 0 [best] to 24 [worst] points), SIRS status (range, 0 [best] to 4 [worst] criteria), and qSOFA scores (range, 0 [best] to 3 [worst] points) were calculated using physiological and laboratory parameters recorded within the first 24 hours of ICU admission. Main outcome measures: SOFA, qSOFA, and SIRS scores were calculated and measured using physiological and laboratory parameters. Patients were followed till mortality (non-survivors) or discharge from the hospital (survivors). Data were analysed using software SPSS version 20. Results: 54 (46.6%) of included patients died. Higher SOFA, qSOFA, and SIRS scores; tachycardia; hypotension; hypoxemia; basophilia; hypoproteinemia; hypoalbuminemia; and need for inotropic support and mechanical ventilation significantly associated with increased mortality. The area under the receiver operating curve for qSOFA ≥2 (0.678; p=0.001) and SOFA (0.74; p=0.000) were comparable and significant, whereas SIRS ≥2 (0.580, p=0.139) was not statistically significant. Conclusions: A qSOFA score of greater than 2 is comparable to SOFA and is better than SIRS score greater than 2 for predicting mortality. Funding: None indicated.
MeSH term(s)	Humans ; Systemic Inflammatory Response Syndrome/diagnosis ; Organ Dysfunction Scores ; Intensive Care Units ; Hospital Mortality ; Prognosis ; Retrospective Studies ; Sepsis/diagnosis ; Tertiary Care Centers ; ROC Curve
Language	English
Publishing date	2023-06-26
Publishing country	Ghana
Document type	Observational Study ; Journal Article
ZDB-ID	2259233-7
ISSN	2616-163X ; 2616-163X
ISSN (online)	2616-163X
ISSN	2616-163X
DOI	10.4314/gmj.v56i3.9
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Article: Curriculum implementation challenges: Development and validation of an integrated curriculum implementation challenges tool.

Aslam, Kinza / Khan, Rehan Ahmed / Aslam, Mohammad Annas / Zaidi, Fatima Zia

Pakistan journal of medical sciences

2023 Volume 40, Issue 1Part-I, Page(s) 89–94

Abstract: Objective: To develop an instrument to identify the challenges faced by faculty while implementing an integrated curriculum in an undergraduate dentistry program.: Methods: The study was conducted between September 2020 and October 2021 at the ... ...

Abstract	Objective: To develop an instrument to identify the challenges faced by faculty while implementing an integrated curriculum in an undergraduate dentistry program. Methods: The study was conducted between September 2020 and October 2021 at the University College of Medicine and Dentistry (UCMD), University of Lahore (UOL). A preliminary questionnaire, developed through literature review and faculty interviews was sent to 10 medical education experts for content validation via the Delphi technique. Content Validity Index (CVI) was calculated for individual items (I-CVI) as well as for the composite scale (S-CVI). A panel agreement of more than 75% was considered as the criterion for the inclusion of items in the questionnaire. Cognitive pretesting of five faculty members was conducted and pilot testing was subsequently done with 27 faculty members. The reliability of the tool was determined by Cronbach's alpha. Results: After the Delphi process, the final Integrated Curriculum Implementation Challenges (ICIC) questionnaire had 42 items. S-CVI was 0.87 and the cut-off value for I-CVI was taken as 0.78 as the criterion for item deletion. Cognitive interviews and pretesting revealed good item interpretation. Cronbach's alpha for this tool was 0.87. Conclusion: ICIC is a useful instrument with good reliability and content validity. It can be used to identify the presence and extent of challenges faced by the faculty while implementing an integrated curriculum.
Language	English
Publishing date	2023-12-09
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.40.1.7258
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Article ; Online: CpG Islands, Gene Expression and Pseudogenization: A Case for a Potential Trilogy.

Khan, Ammad Aslam / Fatima, Anees

Frontiers in bioscience (Scholar edition)

2024 Volume 16, Issue 1, Page(s) 2

Abstract: Background: The promoters of mammalian genes contain clusters of CG dinucleotides known as CpG islands. Most mammalian housekeeping genes predominantly contain CpG islands (CGIs), facilitating gene transcription. Numerous studies have explored the ... ...

Abstract	Background: The promoters of mammalian genes contain clusters of CG dinucleotides known as CpG islands. Most mammalian housekeeping genes predominantly contain CpG islands (CGIs), facilitating gene transcription. Numerous studies have explored the physiological implications of the relationship between CGIs and gene expression. However, the evolutionary implications of this relationship remain largely unexplored. Pseudogenes, in contrast, are genomic remnants that have lost their function over evolutionary time. Methods: In our current research, we employed comparative genomic techniques to demonstrate a correlation between the absence of gene expression due to a lack of CGIs in the gene promoters and pseudogenization. Results: We showed that there is a significant enrichment of tissue-specific genes in the functional orthologs of pseudogenes. We also found a significant correlation between the lack of CGIs and enriched tissue specificity in these functional orthologs of pseudogenes. Conclusions: We inferred that perhaps tissue-specific genes are more prone to the process of pseudogenization. In this way, because of their impact on gene expression, CGIs may affect the fate of a gene. To our knowledge, this is the first study to propose a connection between CGIs, gene expression, and the pseudogenization process and discuss the evolutionary implications of this potential trilogy.
MeSH term(s)	Animals ; CpG Islands/genetics ; Genome ; Genomics ; Mammals/genetics ; Gene Expression
Language	English
Publishing date	2024-03-27
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2565100-6
ISSN	1945-0524 ; 1945-0516
ISSN (online)	1945-0524
ISSN	1945-0516
DOI	10.31083/j.fbs1601002
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