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  1. Book ; Online: La fluorose endémique dans la province du Guizhou (Chine) [lettre] / Li Dasheng, T. W. Cutress

    Li, Dasheng / Cutress, T. W

    1996  

    Keywords Fluoride poisoning ; Fluorine compounds ; Food contamination ; Prevalence ; Arsenic ; China ; Chemical Toxicology and Carcinogenicity ; adverse effects toxicity ; adverse effects
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: Fluorosis endémica en la provincia de Guizhou (China) [carta] / Li Dasheng, T. W. Cutress

    Li, Dasheng / Cutress, T. W

    1996  

    Keywords Fluoride poisoning ; Fluorine compounds ; Food contamination ; Prevalence ; Arsenic ; China ; Chemical Toxicology and Carcinogenicity ; adverse effects toxicity ; adverse effects
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Refined metabolite profiling in the collateral circulation of chronic total occlusion of coronary arteries: Insights from a metabolomics investigation.

    Sigan, Hu / Min, Li / Zengwei, Cheng / Shiyi, Gao / Pinfang, Kang / Dasheng, Gao

    Atherosclerosis plus

    2024  Volume 55, Page(s) 63–73

    Abstract: Background and aims: To investigate the disparities in coronary collateral circulation (CCC) and peripheral serum metabolites among patients presenting with chronic total occlusion (CTO) of the coronary arteries, a non-targeted metabolic approach was ... ...

    Abstract Background and aims: To investigate the disparities in coronary collateral circulation (CCC) and peripheral serum metabolites among patients presenting with chronic total occlusion (CTO) of the coronary arteries, a non-targeted metabolic approach was employed.
    Methods: A cohort of 22 patients diagnosed with CTO of coronary arteries in the context of coronary heart disease (CHD) was selected for blood sample collection from CCC and peripheral arteries. The patients were categorized into two groups, namely CTO-C and CTO-P. The Waters UPLC I-Class Plus is combined with the Q Exactive high-resolution mass spectrometer for metabolite separation and detection. The acquired raw data from mass spectrometry is subsequently imported into Compound Discoverer 3.2 software for comprehensive analysis, which seamlessly integrates the BGI Metabolome Database (BMDB), mzCloud database, and ChemSpider online database. Subsequently, the identified differential metabolites were subjected to a metabolic pathway enrichment analysis, as documented in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database.
    Results: A total of 403 differential metabolites were identified in CCC and peripheral serum samples from patients with CTO of coronary arteries in CHD. Compared to the CTO-P group, the CTO-C group exhibited decreased levels of metabolites such as Testosterone, dehydroepiandrosterone (DHA), deoxyacetone, while demonstrating increased levels of metabolites including Progesterone, androstanone, l-threonine. The biosynthesis pathway of steroid hormones emerges as the key metabolic pathway significantly associated with differential metabolites.
    Conclusions: Through metabolomics analysis, distinct differences in the CCC and peripheral serum metabolites have been identified among patients with CTO of coronary artery. Notably, a significant association between the steroid hormone biosynthesis pathway and CCC has been observed.
    Language English
    Publishing date 2024-02-12
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-0895
    ISSN (online) 2667-0895
    DOI 10.1016/j.athplu.2024.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparative Analysis of Time Series Prediction Algorithms on Multiple Network Function Data of NWDAF

    Dasheng Chen / Qi Song / Yinbin Zhang / Ling Li / Zhiming Yang

    International Journal of Distributed Sensor Networks, Vol

    2024  Volume 2024

    Abstract: With the emergence and vigorous development of 5G technology, there is a significant surge in network usage and traffic, resulting in heightened complexity within network and IT environments. This exponential increase in activity produces a plethora of ... ...

    Abstract With the emergence and vigorous development of 5G technology, there is a significant surge in network usage and traffic, resulting in heightened complexity within network and IT environments. This exponential increase in activity produces a plethora of events, making conventional systems inadequate for the efficient management of 5G networks. In comparison to 4G technology, 5G technology brings forth a host of new features, one of which is the network data analytics function (NWDAF). This function grants network operators the flexibility to either employ their own data analytics methodologies based on machine learning (ML) and deep learning (DL) into their networks. In this paper, we present a dataset named “NWDAF-NFPP” for network function performance time series prediction, collected from a laboratory at China Telecom. The dataset is carefully anonymized to ensure maximum realism and comprehensiveness, while safeguarding sensitive information. It encompasses eight categories of network functions, with data collected at five-minute intervals. The availability of this dataset provides valuable resources for researchers to conduct time series prediction research on network element performance. Following data collection, a total of six models were employed for network element performance prediction, encompassing both machine learning and deep learning approaches. This diverse set of models was carefully chosen to ensure comprehensive coverage of different techniques and algorithms. Through the comparison and analysis of these models, we aim to evaluate their predictive capabilities and identify the most effective approach for network element performance prediction. This comparative analysis will provide valuable insights into the strengths and limitations of each model, aiding in informed decision-making for network optimization and management strategies in the future.
    Keywords Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Hindawi - SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Sacubitril/valsartan mitigated intermittent hypoxia related intestinal microbiota alteration and aortic injury.

    Wang, Jinfeng / Zhang, Hongxiang / Wu, LiJuan / Lu, Dasheng

    Sleep & breathing = Schlaf & Atmung

    2023  Volume 27, Issue 5, Page(s) 1769–1777

    Abstract: Objective: To investigate the influence of sacubitril valsartan sodium (SVS) on chronic intermittent hypoxia (IH) related gut microbiome composition alteration and aortic injury.: Methods: Experiments were performed using SD rats, which were divided ... ...

    Abstract Objective: To investigate the influence of sacubitril valsartan sodium (SVS) on chronic intermittent hypoxia (IH) related gut microbiome composition alteration and aortic injury.
    Methods: Experiments were performed using SD rats, which were divided into three groups: control, IH, and SVS group. O
    Results: Principal coordinate analysis and non-metric multidimensional scaling analysis indicated that the bacterial community was altered by chronic IH exposure, while SVS treatment restored the intestinal microbial communities. Further analysis showed that IH decreased the relative abundance of Lactobacillus and Prevotella, while rats treated with SVS was enriched with Firmicutes, Bacilli, Prevotellaceae, and Lactobacillus, which was similar to control rats. Immunohistochemical staining showed that SVS prevented the upregulation of transforming growth factor-β1 and tumor necrosis factor-alpha in the aorta.
    Conclusion: SVS prevented aortic adverse response to IH, possibly through modulating intestinal microbiota.
    MeSH term(s) Rats ; Animals ; Gastrointestinal Microbiome ; Rats, Sprague-Dawley ; Hypoxia/pathology ; Valsartan/pharmacology
    Chemical Substances sacubitril (17ERJ0MKGI) ; Valsartan (80M03YXJ7I)
    Language English
    Publishing date 2023-01-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-023-02781-9
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    In stock of ZB MED Cologne/Königswinter

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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Study and Evaluation of Dynamic Carrying Capacity of Groundwater Resources in Hebei Province from 2010 to 2017

    Boxin Wang / Bin Wang / Xiaobing Zhao / Jiao Li / Dasheng Zhang

    Sustainability, Vol 15, Iss 4394, p

    2023  Volume 4394

    Abstract: There is a severe issue with groundwater overuse and water scarcity in the North China Plain. The capacity of groundwater resources to promote economic development is also diminished due to the overexploitation of resources to suit the industrial needs ... ...

    Abstract There is a severe issue with groundwater overuse and water scarcity in the North China Plain. The capacity of groundwater resources to promote economic development is also diminished due to the overexploitation of resources to suit the industrial needs of diverse sectors. Therefore, it is crucial to research the regional groundwater resource carrying capacity from both a temporal and spatial perspective. The relationship between water usage efficiency and groundwater availability, which was built using regional data on water supply and consumption as well as gross domestic product, is used in this study to assess the carrying capacity of Hebei’s groundwater resources through time and space. The results show that from the perspective of time, in the years when the groundwater resource exploitation degree is greater than one from 2010 to 2017, the contribution rate of the groundwater resource exploitation to economic development reaches 62.5%, indicating that the economic development of the study area is highly dependent on the groundwater resources. The exploitation degree of groundwater resources is less than one, but the degree of economic development value keeps increasing to nearly 80% and the overexploitation rate is 75% in the total time scale. In terms of spatial scale, only Hengshui City has no overexploitation index, and the overexploitation rate is 9.1%. The overload and severe overload areas account for 45.45%, respectively. Among them, the exploitation degree of groundwater has been in a state of over-saturation, and as economic development depends on groundwater resources, water efficiency needs to be improved through water saving. Optimizing and promoting industrial structures and water-saving technology to further improve water efficiency are key factors to improve the carrying capacity of groundwater resources.
    Keywords groundwater resources ; degree of groundwater exploitation ; water utilization efficiency ; degree of social and economic development ; Hebei ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 550
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
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  7. Article: A preliminary investigation of the relationship between

    Hu, Lanping / Luo, Nana / Li, Lei / Qiu, Dasheng / Hu, Xiaoyan

    Frontiers in oncology

    2023  Volume 13, Page(s) 1171048

    Abstract: Purpose: The goal of the study was to determine the prognostic significance of metabolic parameters in baseline : Methods: Forty patients with pathologically diagnosed AITL who had baseline : Results: The median follow-up was 30.2 months ( ... ...

    Abstract Purpose: The goal of the study was to determine the prognostic significance of metabolic parameters in baseline
    Methods: Forty patients with pathologically diagnosed AITL who had baseline
    Results: The median follow-up was 30.2 months (interquartile range 9.82-43.03). Throughout the follow-up period, 29 (72.5%) deaths occurred and 22 (55.0%) patients made progress. The rates for 2- and 3-year PFS were 43.6% and 26.4%, respectively. The 3- and 5-year OS were 42.6% and 21.5%. For TMTV, TLG, and SUVmax, the cut-off values were 87.0 cm3, 711.1, and 15.8, respectively. Poorer PFS and OS were substantially correlated with high SUVmax and TLG. An increased TMTV suggested a shorter OS. TLG performed independently as OS predictors in multivariate analysis. The risk score for predicting the prognosis of AITL includes the TMTV, TLG, SUVmax, and IPI scores, with 4.5 for TMTV, 2 for TLG, 1.5 for IPI scores, and 1 for SUVmax. Three risk categories of patients with AITL had 3-year OS rates of 100.0%, 43.3%, and 25.0%, respectively.
    Conclusion: Baseline TLG was a strong predictor of OS. Here a new prognostic scoring system for AITL based on the clinical indicators and PET/CT metabolic parameters was constructed, which might make stratification of prognosis easy and also help to individualize treatment.
    Language English
    Publishing date 2023-06-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1171048
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  8. Article: Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach.

    Yin, Tong / Zhang, Han / Liu, Xingfang / Wei, Dongfeng / Ren, Cong / Cui, Liangyu / Li, Yukun / Wang, Linshuang / Wang, Jiaheng / Zhao, Zhiwei / Liu, Dasheng / Wang, Liying / Han, Xuejie

    Frontiers in chemistry

    2024  Volume 12, Page(s) 1356458

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2024.1356458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Chinese patent medicine combined with calcium channel blockers in the treatment of essential hypertension:a Bayes network meta-analysis and systematic review.

    Cui, Liangyu / Liu, Xingfang / Li, Yukun / Jing, Tianyue / Liu, Dasheng / Ren, Cong / Yin, Tong / Wang, Yu / Zhao, Zhiwei / Wang, Jiaheng / Han, Xuejie / Wang, Liying

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1321405

    Abstract: Backgroud: ...

    Abstract Backgroud:
    Language English
    Publishing date 2024-03-15
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1321405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Research on the Wear Behavior of the Fixed Cone Liner of a Cone Crusher Based on the Discrete Element Method

    Dasheng Li / Yonghai Wang / Chao Wang / Sehui Li

    ACS Omega, Vol 5, Iss 19, Pp 11186-

    2020  Volume 11195

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
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