LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 144

Search options

  1. Article: Current status of carotid artery stent placement.

    Wholey, M H

    The Journal of cardiovascular surgery

    2006  Volume 47, Issue 2, Page(s) 101–105

    MeSH term(s) Angioplasty/instrumentation ; Carotid Artery Thrombosis/surgery ; Carotid Stenosis/surgery ; Graft Occlusion, Vascular/prevention & control ; Humans ; Patient Selection ; Stents ; Treatment Outcome
    Language English
    Publishing date 2006-04
    Publishing country Italy
    Document type Editorial
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: What's new in carotid artery stenting.

    Wholey, M H

    The Journal of cardiovascular surgery

    2005  Volume 46, Issue 3, Page(s) 189–192

    MeSH term(s) Blood Vessel Prosthesis Implantation/instrumentation ; Blood Vessel Prosthesis Implantation/trends ; Carotid Stenosis/surgery ; Humans ; Prosthesis Design ; Stents/trends
    Language English
    Publishing date 2005-06
    Publishing country Italy
    Document type Comment ; Editorial
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: First Clinical Experience With Targeted REnal Nerve Demodulation (TREND-1) Using a Neurotropic Agent for the Treatment of Sympathetic Hypertension.

    Kipshidze, Nicholas / Sievert, Horst / Wholey, Michael H / Kipiani, Konstantin / Kipiani, Vakhtang / Mukhuradze, Tea / Wholey, Mark / Stein, Emily / Venkateswara Rao, K T

    The Journal of invasive cardiology

    2017  Volume 29, Issue 3, Page(s) 97–103

    Abstract: Aims: To evaluate the feasibility and safety of a novel targeted neuromodulatory treatment for sympathetic hypertension involving a one-time local injection of neurotropic agents near renal nerves.: Methods and results: Seven patients suffering from ... ...

    Abstract Aims: To evaluate the feasibility and safety of a novel targeted neuromodulatory treatment for sympathetic hypertension involving a one-time local injection of neurotropic agents near renal nerves.
    Methods and results: Seven patients suffering from uncontrolled hypertension per ESH-ESC guidelines were treated using a single dose of NW2013, a neurotropic Na+/K+ ATPase antagonist. A microneedle catheter was used to administer 1.2 mL of NW2013 (0.6 mL per artery) to the perivascular space surrounding renal arteries using percutaneous endovascular procedures under fluoroscopic guidance. All patients were successfully treated without any procedural complications. Patients were followed for 12 months post procedure, and office and 24-hour ambulatory blood pressure measurements were made. Both office and ambulatory blood pressures were lower at 24 hours, 1 month, and 3 months after treatment. The decrease in office blood pressure was greater than the decrease in ambulatory blood pressure. A reduction in medication regimen was also observed in 2 patients. One patient suffered a cerebrovascular event after 6-month follow-up and died from stroke, unrelated to the treatment. Overall, the reduction in office and ambulatory blood pressure was sustained over the course of 12 months.
    Conclusions: Treatment of hypertension using local administration of NW2013 near renal nerves appears to be feasible and safe. Large, controlled, randomized, and blinded clinical studies with monitoring of patient compliance to daily oral medication are recommended to further establish the efficacy of this novel treatment.
    Language English
    Publishing date 2017-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3701: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 272: Show issues
    Zs.MG 31: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Common Cervical and Cerebral Vascular Variants.

    Thurlow, Peter C / Andrus, Jason M / Wholey, Mark H

    Interventional cardiology clinics

    2014  Volume 3, Issue 1, Page(s) 123–134

    Abstract: Successful open and endovascular carotid artery intervention depends on a thorough foundational knowledge of cervical and intracranial vascular anatomy. It is essential for the carotid interventionist to be familiar with the common and rare variants of ... ...

    Abstract Successful open and endovascular carotid artery intervention depends on a thorough foundational knowledge of cervical and intracranial vascular anatomy. It is essential for the carotid interventionist to be familiar with the common and rare variants of the cervical and intracranial vasculature, and to understand the implications of these variants for the performance of carotid intervention with protection of the distal circulation. This article provides interventionists with a basic description of the normal and relevant variant vascular anatomy from the aortic arch to the circle of Willis, and outlines the potential difficulties that specific variants may present for endovascular therapy.
    Language English
    Publishing date 2014-01
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2013.09.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Current status in cervical carotid artery stent placement.

    Wholey, M H / Wholey, M

    The Journal of cardiovascular surgery

    2003  Volume 44, Issue 3, Page(s) 331–339

    Abstract: Aim of this paper is to provide background information and the latest developments and studies pertaining to carotid artery stent placement in the treatment of carotid artery occlusive disease. A review of current literature combined with personal ... ...

    Abstract Aim of this paper is to provide background information and the latest developments and studies pertaining to carotid artery stent placement in the treatment of carotid artery occlusive disease. A review of current literature combined with personal experience in the field of carotid stenting is presented. Endovascular stent placement for carotid artery occlusive disease is evolving from its initial controversial position to that of an alternative treatment of extracranial carotid artery disease. The high technical success (98-99%) as well as the relatively few complications makes carotid stenting a substitute for carotid endarterectomy for symptomatic patients and especially those with high medical comorbidities. With the advent of distal embolic protection, the complication rates for carotid stenting have decreased by approximately 50% to 2-4% for most major centers. Hence, with improved technology, carotid stenting is becoming an option for asymptomatic patients, especially those with high surgical risk. Early results for patency and neurological follow-up have also been encouraging. When we first began performing carotid stenting in 1995, we used a mixture of peripheral and coronary techniques. As stent design, guide catheters and cerebral protection devices have become dedicated and sophisticated, the technical success, patency and complication rates have improved. Carotid stenting will increase in application in the future especially among high surgical-risk patients with symptomatic and asymptomatic carotid occlusive disease.
    MeSH term(s) Angioplasty, Balloon/instrumentation ; Brain Ischemia/mortality ; Brain Ischemia/prevention & control ; Carotid Stenosis/diagnosis ; Carotid Stenosis/mortality ; Carotid Stenosis/therapy ; Clinical Trials as Topic ; Diagnostic Imaging ; Endarterectomy ; Equipment Design ; Humans ; Intracranial Embolism/mortality ; Intracranial Embolism/prevention & control ; Outcome and Process Assessment (Health Care) ; Risk Factors ; Stents ; Survival Rate
    Language English
    Publishing date 2003-06
    Publishing country Italy
    Document type Comparative Study ; Journal Article
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: The expanding indications for virtual histology intravascular ultrasound for plaque analysis prior to carotid stenting.

    Schiro, B J / Wholey, M H

    The Journal of cardiovascular surgery

    2008  Volume 49, Issue 6, Page(s) 729–736

    Abstract: Complications of carotid artery stenting (CAS), including stroke, remain relatively high when compared with carotid endarterectomy (CEA). Current selection criteria for patients undergoing CAS are based predominately on surgical risk related to other ... ...

    Abstract Complications of carotid artery stenting (CAS), including stroke, remain relatively high when compared with carotid endarterectomy (CEA). Current selection criteria for patients undergoing CAS are based predominately on surgical risk related to other comorbidities. Little attention is given to the morphology of the atherosclerotic plaque, although studies have shown that extensive variability exists which confers certain risks for plaque vulnerability. Virtual Histology intravascular ultrasound (VH IVUS) offers a unique method of assessing plaque morphology prior to CAS. Herein, the authors review the concepts of atherosclerotic plaque morphology and discuss the background of VH IVUS and illustrate its use in the carotid system. With selection of the appropriate patient and the appropriate plaque, more favorable outcomes of CAS may be achieved which will solidify its place as a frontline treatment of carotid vascular disease.
    MeSH term(s) Angioplasty, Balloon ; Carotid Arteries/diagnostic imaging ; Carotid Artery Diseases/diagnostic imaging ; Carotid Artery Diseases/therapy ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/therapy ; Humans ; Stents ; Ultrasonography, Interventional
    Language English
    Publishing date 2008-12
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 469: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Do the benefits of angiography outweigh the risks in the treatment of patients with carotid artery occlusive disease?

    Wholey, M H

    Cardiovascular and interventional radiology

    1999  Volume 22, Issue 3, Page(s) 183–184

    MeSH term(s) Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/surgery ; Cerebral Angiography/adverse effects ; Cerebrovascular Disorders/epidemiology ; Endarterectomy, Carotid ; Humans ; Risk Assessment ; Ultrasonography
    Language English
    Publishing date 1999-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0174-1551 ; 0342-7196
    ISSN (online) 1432-086X
    ISSN 0174-1551 ; 0342-7196
    DOI 10.1007/s002709900362
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1378: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Randomizing carotid endarterectomy to carotid stenting?

    Wholey, M H

    Journal of endovascular surgery : the official journal of the International Society for Endovascular Surgery

    1999  Volume 6, Issue 2, Page(s) 127–9; discussion 130

    MeSH term(s) Carotid Artery Diseases/surgery ; Cerebrovascular Disorders/prevention & control ; Decision Making ; Endarterectomy, Carotid ; Humans ; Multicenter Studies as Topic ; Randomized Controlled Trials as Topic ; Stents
    Language English
    Publishing date 1999-05
    Publishing country United States
    Document type Editorial ; Review
    ZDB-ID 1327353-x
    ISSN 1074-6218
    ISSN 1074-6218
    DOI 10.1583/1074-6218(1999)006<0127:RCETCS>2.0.CO;2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4547: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: A comparative analysis of bench-top performance assessment of distal protection filters in transient flow conditions.

    Siewiorek, Gail M / Wholey, Mark H / Finol, Ender A

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2012  Volume 19, Issue 2, Page(s) 249–260

    Abstract: Purpose: To compare the performance in vitro of 6 distal protection filters (DPFs) on the basis of filtration ability and effects on pressure gradient and vascular impedance in a flow model of the internal carotid artery (ICA).: Methods: Six DPFs ( ... ...

    Abstract Purpose: To compare the performance in vitro of 6 distal protection filters (DPFs) on the basis of filtration ability and effects on pressure gradient and vascular impedance in a flow model of the internal carotid artery (ICA).
    Methods: Six DPFs (Accunet, Angioguard, FilterWire, Gore Embolic Filter, NAV6, and SpiderFX) were evaluated in a physiologically realistic flow loop. A blood analog was heated to body temperature and circulated by a pulsatile pump outputting a time-varying flow rate representative of the ICA. The ICA flow model was a highly curved tube representing a challenging site for filter deployment. The DPFs were deployed at the apex of the curved segment, and 2 sizes of microspheres (143 and 200 µm) were injected to simulate embolization. The capture efficiency, pressure gradient, normalized pressure gradient, and vascular impedance were calculated.
    Results: The Gore filter had high capture efficiency (143 µm: 99.97%; 200 µm: 100.00%) with relatively small increases in pressure gradient (143 µm: +27%; 200 µm: +20%) and vascular impedance (143 µm: +23.4%; 200 µm: +6.1%) after particles were injected. Spider had the lowest capture efficiency (143 µm: 1.50%; 200 µm: 19.34%, p<0.0005), while NAV6 (143 µm: +916%, p<0.0005) and Accunet (200 µm: +179%, p<0.0005) yielded the largest pressure gradient increases.
    Conclusion: A bench-top flow apparatus exhibiting physiologically realistic conditions was developed by combining pulsatile flow and a body temperature blood analog. Using microspheres larger than the pore size of most of the DPFs, the device-wall apposition has an important effect on the overall filter performance and the global fluid dynamics in the flow model.
    MeSH term(s) Blood Pressure ; Body Temperature ; Carotid Artery, Internal/pathology ; Carotid Artery, Internal/physiopathology ; Carotid Stenosis/pathology ; Carotid Stenosis/physiopathology ; Carotid Stenosis/therapy ; Embolic Protection Devices ; Hemodynamics ; Humans ; Infusion Pumps ; Materials Testing ; Microspheres ; Models, Cardiovascular ; Polymers ; Prosthesis Design ; Pulsatile Flow ; Regional Blood Flow ; Time Factors
    Chemical Substances Polymers
    Keywords covid19
    Language English
    Publishing date 2012-04
    Publishing country United States
    Document type Comparative Study ; Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1583/11-3720.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4547: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Carotid artery stenting update.

    Cilingiroglu, Mehmet / Marmagkiolis, Konstantinos / Wholey, Mark H

    Future cardiology

    2013  Volume 9, Issue 2, Page(s) 193–197

    Abstract: Stroke is the third leading cause of death and the most common cause of long-term disability in the USA. Approximately 25% of strokes are due to carotid artery disease. The mechanisms of stroke include thrombotic occlusion, thrombus embolism, ... ...

    Abstract Stroke is the third leading cause of death and the most common cause of long-term disability in the USA. Approximately 25% of strokes are due to carotid artery disease. The mechanisms of stroke include thrombotic occlusion, thrombus embolism, atheroembolism and dissection or subintimal hematoma. Today, endarterectomy is the standard of care for management of significant carotid artery disease. The SAPPHIRE trial has proved the noninferiority of carotid artery stenting versus carotid endarterectomy in 'high-risk' patients, which led to the US FDA approval of carotid stent for high-risk patients. The CREST trial is the largest randomized trial comparing stenting versus endarterectomy and showed no significant difference in death, stroke or myocardial infarction. Over the last 15 years, the accumulation of experience, the improvement of stent platforms and embolic protection devices, and the strong demand from patients for a less invasive alternative to carotid endarterectomy has made carotid artery stenting an equally efficient and safe procedure for the prevention of stroke.
    MeSH term(s) Carotid Artery Diseases/surgery ; Carotid Artery Diseases/therapy ; Carotid Stenosis/therapy ; Clinical Trials as Topic ; Endarterectomy, Carotid ; Humans ; Magnetic Resonance Angiography ; Medicare ; Stents ; Stroke/prevention & control ; Treatment Outcome ; United States
    Language English
    Publishing date 2013-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca.12.84
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6836: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top