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  1. Article: [Study on absorption and accumulation of mercury in rats by repeated administration of Yuhong ointment].

    Qiu, Heng / Sun, Xin-Min / Huang, Wen / Hu, Xiao-Jing / Wang, Qi / Mou, Ji-Zheng / Wang, Li-Xia

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2013  Volume 38, Issue 6, Page(s) 884–888

    Abstract: ... administration of Yuhong ointment containing calomel, in order to provide scientific evidences for clinical safe ... the Yuhong ointment group, the double-concentration Yuhong Ointment group, the quadruple-concentration Yuhong ... Result: Compared with the control group, the blood mercury level of the Yuhong ointment group show no ...

    Abstract Objective: To study in vivo mercury absorption and accumulation through repeated transdermal administration of Yuhong ointment containing calomel, in order to provide scientific evidences for clinical safe medication.
    Method: A total of 100 SD rats were randomly classified into five groups: the control group, the Yuhong ointment group, the double-concentration Yuhong Ointment group, the quadruple-concentration Yuhong ointment group and the 1.6% calomel group. The rats were treated with the dosage of 0.04 g . cm-2 by repeated transdermal administration for 2, 4 weeks. After the drug discontinuance for 4 weeks, the levels of mercury in blood, urine, and tissues of heart, liver, brain and kidney were determined, respectively.
    Result: Compared with the control group, the blood mercury level of the Yuhong ointment group show no obvious change after treatment for 4 weeks. However, the levels of mercury in blood and urine of other experimental groups increased significantly with time and the increase in dosage, and so did the level of mercury in major organ. At 4 weeks, all experimental groups showed increase in the content of mercury, and kidneys displayed the highest level, whereas brain displayed the lowest level After the drug discontinuance for 4 weeks, the mercury level in blood and urine of every dose group recovered to normal, with significant decline in the content of mercury in each organ.
    Conclusion: After transdermal administration in rats for 4 weeks, there was no obvious absorption of mercury in blood. Mercury was mainly accumulated in kidneys and excreted through urine. The results suggest that the patients' mercury content and kidney function indexes need to be monitored in long-term clinical use of Yuhong ointment.
    MeSH term(s) Absorption/drug effects ; Animals ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/adverse effects ; Female ; Male ; Mercury/analysis ; Mercury/blood ; Mercury/pharmacokinetics ; Mercury/urine ; Ointments ; Rats ; Rats, Sprague-Dawley ; Safety ; Time Factors
    Chemical Substances Drugs, Chinese Herbal ; Ointments ; Mercury (FXS1BY2PGL)
    Language Chinese
    Publishing date 2013-03
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Determination of mercury content in yuhong ointment by wet catalytic digestion-atomic absorption spectrometry].

    Sun, Xinmin / Wang, Qi / Mu, Jizheng / Wang, Lixia

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2012  Volume 37, Issue 6, Page(s) 744–745

    Abstract: Objective: To develop a method for determining the content of mercury contained in Yuhong ointment ... in Yuhong ointment was determined by hydride generation-atomic absorption spectrometry (HG-AAS).: Result ... The mercury content in Yuhong ointment was detected in range from 0.7 to 1.5 mg x g(-1).: Conclusion: The proposed ...

    Abstract Objective: To develop a method for determining the content of mercury contained in Yuhong ointment.
    Method: The wet catalytic digestion method was adopted for the pretreatment, and the mercury content in Yuhong ointment was determined by hydride generation-atomic absorption spectrometry (HG-AAS).
    Result: The mercury showed a good linear relation in the range from 2 to 20 microg x L(-1), with the average recovery of 104.27% and RSD of 3.37%. The RSD for real sample repeated measurement was determined to be 8.4%. The mercury content in Yuhong ointment was detected in range from 0.7 to 1.5 mg x g(-1).
    Conclusion: The proposed method is accurate, highly reproducible and it can be used to control mercury content of Yuhong ointment.
    MeSH term(s) Catalysis ; Drugs, Chinese Herbal/chemistry ; Mercury/analysis ; Mercury/isolation & purification ; Ointments ; Reference Standards ; Reproducibility of Results ; Spectrophotometry, Atomic/methods
    Chemical Substances Drugs, Chinese Herbal ; Ointments ; Mercury (FXS1BY2PGL)
    Language Chinese
    Publishing date 2012-03
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Ribozyme synthesis of both L- and D- amino acid oligos.

    Wang, Yuhong

    bioRxiv : the preprint server for biology

    2023  

    Abstract: The ribosome is responsible for assembling proteins using 20 naturally occurring L-handed amino acids. However, incorporating non-natural amino acids into a protein is a challenging process needs improvement. In this study, we report a new possible ... ...

    Abstract The ribosome is responsible for assembling proteins using 20 naturally occurring L-handed amino acids. However, incorporating non-natural amino acids into a protein is a challenging process needs improvement. In this study, we report a new possible approach to creating nonnatural peptides using ribozymes inspired by the peptidyl transfer center. These RNA scaffolds, which are approximately 100 nucleotides in length, bind to RNase T1 truncated tRNA-like chimeras and bring them into close proximity to facilitate peptide ligation. We used single-molecule fluorescence resonance energy transfer (smFRET) to show close distances between RNA-RNA, tRNA
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.04.28.538729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Systematic Study on the Extraction and Image Reproduction of Ceramic Sculpture Artworks

    Yuhong Wang

    International Journal of Analytical Chemistry, Vol

    2022  Volume 2022

    Abstract: In order to solve the research on the extraction of ceramic sculpture artwork patterns, and, in the process of image reproduction, the problem of too few feature points in the object image, the author proposes an image stitching algorithm that combines ... ...

    Abstract In order to solve the research on the extraction of ceramic sculpture artwork patterns, and, in the process of image reproduction, the problem of too few feature points in the object image, the author proposes an image stitching algorithm that combines SIFT and MSER algorithms. After comprehensively analyzing the principles, advantages, and disadvantages of the current main image stitching methods, in terms of feature matching, based on the K-D tree search algorithm, the improved BBF algorithm is used to improve the search efficiency of feature points. In order to remove the possible cracks in the stitching process, an improved multiband fusion algorithm is used to seamlessly stitch the registered images. The results show that the feature points detected by the one-dimensional normal distribution algorithm are on average 0.1%, 0.5%, 1.7%, 4.4%, and 9.2%. The algorithm combining SIFT and MSER to extract feature points can reach 3.6%, 4.6%, 8.4%, 15%, and 19.1%. The experimental results show that the algorithm proposed by the author can extract more image feature points to facilitate later image registration. The image blur phenomenon in the original image fusion algorithm is solved, and a complete and clear two-dimensional plane pattern is finally obtained.
    Keywords Analytical chemistry ; QD71-142
    Subject code 006
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: A Systematic Study on the Extraction and Image Reproduction of Ceramic Sculpture Artworks.

    Wang, Yuhong

    publication RETRACTED

    International journal of analytical chemistry

    2022  Volume 2022, Page(s) 6752589

    Abstract: In order to solve the research on the extraction of ceramic sculpture artwork patterns, and, in the process of image reproduction, the problem of too few feature points in the object image, the author proposes an image stitching algorithm that combines ... ...

    Abstract In order to solve the research on the extraction of ceramic sculpture artwork patterns, and, in the process of image reproduction, the problem of too few feature points in the object image, the author proposes an image stitching algorithm that combines SIFT and MSER algorithms. After comprehensively analyzing the principles, advantages, and disadvantages of the current main image stitching methods, in terms of feature matching, based on the K-D tree search algorithm, the improved BBF algorithm is used to improve the search efficiency of feature points. In order to remove the possible cracks in the stitching process, an improved multiband fusion algorithm is used to seamlessly stitch the registered images. The results show that the feature points detected by the one-dimensional normal distribution algorithm are on average 0.1%, 0.5%, 1.7%, 4.4%, and 9.2%. The algorithm combining SIFT and MSER to extract feature points can reach 3.6%, 4.6%, 8.4%, 15%, and 19.1%. The experimental results show that the algorithm proposed by the author can extract more image feature points to facilitate later image registration. The image blur phenomenon in the original image fusion algorithm is solved, and a complete and clear two-dimensional plane pattern is finally obtained.
    Language English
    Publishing date 2022-08-27
    Publishing country Egypt
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2494714-3
    ISSN 1687-8779 ; 1687-8760
    ISSN (online) 1687-8779
    ISSN 1687-8760
    DOI 10.1155/2022/6752589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Malignant ovarian tumors during pregnancy: Diagnostic evaluation, optimal treatment, and future perspective.

    Sheng, Yaru / Yuan, Jiangjing / Li, Yuhong / Wang, Yudong

    Chinese medical journal

    2024  

    Language English
    Publishing date 2024-01-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000002872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1207: Show issues Location:
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  7. Article ; Online: Synthesis and characterization of ZrO

    Liu, Hang / Li, Shenghui / Wang, Lvqing / Yang, Shengjue / Zhang, Yuhong

    RSC advances

    2024  Volume 14, Issue 5, Page(s) 2983–2992

    Abstract: We prepared ... ...

    Abstract We prepared ZrO
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra06701g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Au/ZnO/In

    Zhang, Yuhong / Wang, Lvqing / Li, Shenghui / Yang, Shengjue / Liu, Hang

    RSC advances

    2024  Volume 14, Issue 5, Page(s) 3044–3051

    Abstract: In this paper, a series of Au/ZnO/ ... ...

    Abstract In this paper, a series of Au/ZnO/In
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra07507a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: RegGAN: A Virtual Sample Generative Network for Developing Soft Sensors with Small Data.

    Wang, Yuhong / Yan, Pengfei

    ACS omega

    2024  Volume 9, Issue 5, Page(s) 5954–5965

    Abstract: Quality variables play a pivotal role in monitoring the performance of chemical production systems. However, certain critical quality variables cannot be measured online through instruments. In such scenarios, using soft sensors becomes imperative to ... ...

    Abstract Quality variables play a pivotal role in monitoring the performance of chemical production systems. However, certain critical quality variables cannot be measured online through instruments. In such scenarios, using soft sensors becomes imperative to enable real-time measurements, accurately reflecting the system's operational status. The development of high-performance soft sensors requires abundantly labeled samples. Nevertheless, the prolonged periods and substantial costs associated with acquiring quality variable data pose challenges in obtaining sufficient labeled samples. Therefore, this paper proposes a regression generative adversarial network to generate virtual samples. The proposed method considers the mapping relationship between auxiliary and target variables while learning the data distribution. Moreover, the importance-weighted autoencoder is introduced to enhance the training stability of the generative model. The virtual samples, selected by using the similarity measurement algorithm, are incorporated into the training set. This inclusion addresses the diminished predictive performance of soft sensors when labeled samples are insufficient. The soft sensor employed in the anaerobic digestion process serves as a case study to illustrate the efficacy of the proposed generative method. Experimental results validate that the virtual samples generated by the proposed method exhibit greater proximity to the actual samples compared to those of other methods. Furthermore, integrating virtual samples into the training process of the long short-term memory-based soft sensor yields a 21.03% reduction in root-mean-square error compared with that of using the original training set alone.
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c09762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis.

    Wang, Yuhong

    Journal of visualized experiments : JoVE

    2021  , Issue 173

    Abstract: The ribosome is a large ribonucleoprotein complex that assembles proteins processively along mRNA templates. The diameter of the ribosome is approximately 20 nm to accommodate large tRNA substrates at the A-, P- and E-sites. Consequently, the ribosome ... ...

    Abstract The ribosome is a large ribonucleoprotein complex that assembles proteins processively along mRNA templates. The diameter of the ribosome is approximately 20 nm to accommodate large tRNA substrates at the A-, P- and E-sites. Consequently, the ribosome dynamics are naturally de-phased quickly. Single molecule method can detect each ribosome separately and distinguish inhomogeneous populations, which is essential to reveal the complicated mechanisms of multi-component systems. We report the details of a smFRET method based on the Nikon Ti2 inverted microscope to probe the ribosome dynamics between the ribosomal protein L27 and tRNAs. The L27 is labeled at its unique Cys 53 position and reconstituted into a ribosome that is engineered to lack L27. The tRNA is labeled at its elbow region. As the tRNA moves to different locations inside the ribosome during the elongation cycle, such as pre- and post- translocation, the FRET efficiencies and dynamics exhibit differences, which have suggested multiple subpopulations. These subpopulations are not detectable by ensemble methods. The TIRF-based smFRET microscope is built on a manual or motorized inverted microscope, with home-built laser illumination. The ribosome samples are purified by ultracentrifugation, loaded into a home-built multi-channel sample cell and then illuminated via an evanescent laser field. The reflection laser spot can be used to achieve feedback control of perfect focus. The fluorescence signals are separated by a motorized filter-turret and collected by two digital CMOS cameras. The intensities are retrieved via the NIS-Elements software.
    MeSH term(s) Fluorescence Resonance Energy Transfer ; Protein Biosynthesis ; RNA, Messenger/metabolism ; RNA, Transfer/metabolism ; Ribosomes/metabolism
    Chemical Substances RNA, Messenger ; RNA, Transfer (9014-25-9)
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/62664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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