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  1. Book ; Online: Ukrainian Private Law and the European Area of Justice

    Kurzynsky-Singer, Eugenia / Kulms, Rainer

    2019  

    Keywords Private international law & conflict of laws ; Civil codes / Civil law ; Comparative law ; Law ; Conflict of Laws ; Civil Law ; Comparative
    Language English
    Size 1 Online-Ressource
    Document type Book ; Online
    Note English
    HBZ-ID HT030382230
    ISBN 9783161562051 ; 3161562054
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Immuno-oncologic care during COVID-19: Challenges and opportunities for improving clinical care and investigation.

    Spencer, Kristen / Singer, Eric A / Girda, Eugenia

    Journal of cancer biology

    2022  Volume 2, Issue 3, Page(s) 75–82

    Abstract: Cancer care has been greatly impacted during the COVID-19 pandemic. The number of cases and deaths caused by the COVID-19 pandemic continues to escalate throughout the United States and the world. Worldwide, over 150 million people have been diagnosed ... ...

    Abstract Cancer care has been greatly impacted during the COVID-19 pandemic. The number of cases and deaths caused by the COVID-19 pandemic continues to escalate throughout the United States and the world. Worldwide, over 150 million people have been diagnosed with the coronavirus and more than 3 million have died. Now that we have gained additional experience with COVID-19, we are starting to learn its full impact on oncology care and its effects on the practice of medicine and clinical research.
    Language English
    Publishing date 2022-02-15
    Publishing country United States
    Document type Journal Article
    DOI 10.46439/cancerbiology.2.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Can 'eugenics' be defended?

    Veit, Walter / Anomaly, Jonathan / Agar, Nicholas / Singer, Peter / Fleischman, Diana S / Minerva, Francesca

    Monash bioethics review

    2021  Volume 39, Issue 1, Page(s) 60–67

    Abstract: ... particular practices and emerging bio-technologies such as CRISPR 'eugenics', rather than the more important ... the question of whether 'eugenics' can be defended and how proponents and critics of enhancement should engage with each other. ...

    Abstract In recent years, bioethical discourse around the topic of 'genetic enhancement' has become increasingly politicized. We fear there is too much focus on the semantic question of whether we should call particular practices and emerging bio-technologies such as CRISPR 'eugenics', rather than the more important question of how we should view them from the perspective of ethics and policy. Here, we address the question of whether 'eugenics' can be defended and how proponents and critics of enhancement should engage with each other.
    MeSH term(s) Clustered Regularly Interspaced Short Palindromic Repeats ; Eugenics ; Genetic Enhancement ; Humans
    Language English
    Publishing date 2021-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2510076-2
    ISSN 1836-6716 ; 1321-2753
    ISSN (online) 1836-6716
    ISSN 1321-2753
    DOI 10.1007/s40592-021-00129-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Publication rates of podium presentations at the Society of Gynecologic Oncology (SGO) annual meetings.

    Chua, Katherine Jane / Moughrabi, Samira / Glassman, Danielle / Habib, Samer / Singer, Eric A / Girda, Eugenia

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2023  Volume 33, Issue 8, Page(s) 1203–1207

    Abstract: Objectives: Our study aimed to determine the publication rates of podium presentations from the 2017 and 2018 Society of Gynecologic Oncology (SGO) Annual Meetings; and to examine rates and predictors of oral presentations that resulted in publication.!# ...

    Abstract Objectives: Our study aimed to determine the publication rates of podium presentations from the 2017 and 2018 Society of Gynecologic Oncology (SGO) Annual Meetings; and to examine rates and predictors of oral presentations that resulted in publication.
    Methods: We reviewed podium presentations given at the 2017 and 2018 SGO Annual Meetings. Abstracts were evaluated for publication from January 1, 2017 to March 30, 2020 and January 1, 2018 to June 30, 2021, respectively, to allow for a 3 year period of publication.
    Results: In 2017 and 2018, 43 of 75 (57.3%) and 47 of 83 (56.6%) podium presentations were published within 3 years, respectively. No significant difference was found between the mean time to publication within 3 years (13.0 months vs 14.1 months for 2017 and 2018, respectively; p=0.96). Similarly, the mean difference of journal impact factors between both years did not reach significance (6.57 and 10.7 for 2017 and 2018, respectively; p=0.09). The median impact factor (IF) was 4.54 (range: 40.3) and 4.62 (range: 70.7) in 2017 and 2018, respectively. Of the presentations published, 53.4% (2017) and 38.3% (2018) appeared in the journal Gynecologic Oncology. Significant positive correlations for the likelihood of publication were determined among the following: funding status (r=0.93) including funding involving National Institutes for Health (r=0.91) or pharmaceutical (r=0.95), clinical trial study design (r=0.94), and pre-clinical research (r=0.95) (all p<0.005).
    Conclusions: At the 2017 and 2018 SGO Annual Meetings 57% of podium presentations were published in a peer-reviewed journal within 3 years. Publication in peer-reviewed journals is crucial for timely distribution of clinical information to the medical community.
    MeSH term(s) Humans ; Female ; Societies, Medical ; Research Design
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2023-004324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Online ; Thesis: Neutrophilen-Gelatinase-assoziiertes Lipokalin (NGAL) als Biomarker zur Differenzialdiagnose und Prognoseabschätzung bei akutem Nierenversagen

    Singer, Eugenia

    2013  

    Title variant Urinary neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in differential diagnosis and prognosis of acute kidney injury
    Author's details Eugenia Singer
    Language German
    Size Online-Ressource (Online-Ressource)
    Publisher Medizinische Fakultät Charité - Universitätsmedizin Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Berlin, Medizinische Fakultät Charité - Universitätsmedizin Berlin, Diss., 2013
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Transformation durch Rezeption?

    Kurzynsky-Singer, Eugenia

    Möglichkeiten und Grenzen des Rechtstransfers am Beispiel der Zivilrechtsreformen im Kaukasus und in Zentralasien

    (Beiträge zum ausländischen und internationalen Privatrecht ; 102)

    2014  

    Author's details hrsg. von Eugenia Kurzynsky-Singer
    Series title Beiträge zum ausländischen und internationalen Privatrecht ; 102
    Keywords Rechtstransfer ; Privatrecht ; Mittelasien ; Kaukasusländer
    Language German ; English
    Size XIV, 512 S., Ill.
    Publisher Mohr Siebeck
    Publishing place Tübingen
    Document type Book
    Note Beitr. überw. dt., teilw. engl.
    ISBN 9783161533198 ; 3161533194
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book ; Online ; Thesis: Neutrophilen-Gelatinase-assoziiertes Lipokalin (NGAL) als Biomarker zur Differenzialdiagnose und Prognoseabschätzung bei akutem Nierenversagen

    Singer, Eugenia [Verfasser]

    2013  

    Author's details Eugenia Singer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Medizinische Fakultät Charité - Universitätsmedizin Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Article ; Online: Evaluation of audit and feedback to family physicians on prescribing of opioid analgesics to opioid-naïve patients: A pragmatic randomized delay trial.

    McCracken, Rita K / Narayan, Shawna / Maclure, Malcolm / Cooper, Ian / Cui, Zishan / Cullen, Walter / Dormuth, Colin / Hamilton, Michee-Ana / Nolan, Seonaid / Singer, Joel / Socías, M Eugenia / Wong, Sabrina / Klimas, Jan

    Contemporary clinical trials

    2023  Volume 134, Page(s) 107354

    Abstract: Background: Exposure to opioid analgesics have historically raised concern for a risk of developing opioid use disorder. Prescriber audit-and-feedback interventions may reduce opioid prescribing, but some studies have shown detrimental effects for ... ...

    Abstract Background: Exposure to opioid analgesics have historically raised concern for a risk of developing opioid use disorder. Prescriber audit-and-feedback interventions may reduce opioid prescribing, but some studies have shown detrimental effects for current users. We examined the effectiveness of an audit and feedback intervention, named Portrait, to reduce initiation of opioid analgesics among opioid-naïve patients experiencing pain.
    Methods: REDONNA was a single-blinded, two-arm (Early vs Delayed mailing) randomized trial of a portrait for eligible family physicians (FPs) in British Columbia (BC), Canada. The primary outcome was the change in the number of initiations of opioid analgesic prescriptions written by FPs for acute/chronic pain management. We compared outcomes for a 6-month window before vs. after each mailed intervention, using differences in percent differences (DPD) with 95% confidence intervals (CI) and odds ratios (OR) from logistic regressions adjusted for clustering of patients by FP.
    Results: In the Early (n = 2260) and Delayed (n = 2156) groups, opioid initiations per month were the same in the Before (2.10 Early; 2.06 Delayed) and After (1.94 Early; 1.95 Delayed) windows. The DPD was -2.1% (CI: -4.4% to 0.3%), and ORs were: 0.98 (CI: 0.96 to 1.01) for any opioid, 0.97 (CI: 0.94 to 1.01) for codeine (62% of initiations), and 1.0 (CI: 0.97 to 1.07) for tramadol (25% of initiations). There were no differences in mean quantity of tablets, mean milligrams of morphine equivalents (MME), or mean number of days.
    Conclusion: Portrait had no impact on FPs' rates of prescribing opioid analgesics to opioid-naïve patients experiencing pain.
    Trial registration: The study was registered prospectively on 30 March 2020 at the ISRCTN Register (https://www.isrctn.com/ISRCTN34246811).
    MeSH term(s) Humans ; Analgesics, Opioid/therapeutic use ; Feedback ; Pain ; Physicians, Family ; Practice Patterns, Physicians'
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article ; Pragmatic Clinical Trial ; Randomized Controlled Trial
    ZDB-ID 2182176-8
    ISSN 1559-2030 ; 1551-7144
    ISSN (online) 1559-2030
    ISSN 1551-7144
    DOI 10.1016/j.cct.2023.107354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1581: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Online: Transformation durch Rezeption?

    Kurzynsky-Singer, Eugenia

    Möglichkeiten und Grenzen des Rechtstransfers am Beispiel der Zivilrechtsreform im Kaukasus und in Zentralasien

    (Beiträge zum ausländischen und internationalen Privatrecht ; v.102)

    2014  

    Abstract: ... Reihe ... Beiträge zum ausländischen und internationalen Privatrecht - Band ... ...

    Series title Beiträge zum ausländischen und internationalen Privatrecht ; v.102
    Abstract Reihe Beiträge zum ausländischen und internationalen Privatrecht - Band 102
    Language German
    Size Online-Ressource (527 p)
    Publisher Mohr Siebeck
    Publishing place Tübingen
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9783161533198 ; 3161533194
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Article ; Online: Plasma NGAL levels in stable kidney transplant recipients and the risk of allograft loss.

    Swolinsky, Jutta S / Hinz, Ricarda M / Markus, Carolin E / Singer, Eugenia / Bachmann, Friederike / Halleck, Fabian / Kron, Susanne / Naik, Marcel G / Schmidt, Danilo / Obermeier, Martin / Gebert, Pimrapat / Rauch, Geraldine / Kropf, Siegfried / Haase, Michael / Budde, Klemens / Eckardt, Kai-Uwe / Westhoff, Timm H / Schmidt-Ott, Kai M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2023  Volume 39, Issue 3, Page(s) 483–495

    Abstract: Background: The objective of this study was to investigate the utility of neutrophil gelatinase-associated lipocalin (NGAL) and calprotectin (CPT) to predict long-term graft survival in stable kidney transplant recipients (KTR).: Methods: A total of ... ...

    Abstract Background: The objective of this study was to investigate the utility of neutrophil gelatinase-associated lipocalin (NGAL) and calprotectin (CPT) to predict long-term graft survival in stable kidney transplant recipients (KTR).
    Methods: A total of 709 stable outpatient KTR were enrolled >2 months post-transplant. The utility of plasma and urinary NGAL (pNGAL, uNGAL) and plasma and urinary CPT at enrollment to predict death-censored graft loss was evaluated during a 58-month follow-up.
    Results: Among biomarkers, pNGAL showed the best predictive ability for graft loss and was the only biomarker with an area under the curve (AUC) > 0.7 for graft loss within 5 years. Patients with graft loss within 5 years (n = 49) had a median pNGAL of 304 [interquartile range (IQR) 235-358] versus 182 (IQR 128-246) ng/mL with surviving grafts (P < .001). Time-dependent receiver operating characteristic analyses at 58 months indicated an AUC for pNGAL of 0.795, serum creatinine-based Chronic Kidney Disease Epidemiology Collaboration estimated glomerular filtration rate (eGFR) had an AUC of 0.866. pNGAL added to a model based on conventional risk factors for graft loss with death as competing risk (age, transplant age, presence of donor-specific antibodies, presence of proteinuria, history of delayed graft function) had a strong independent association with graft loss {subdistribution hazard ratio (sHR) for binary log-transformed pNGAL [log2(pNGAL)] 3.4, 95% confidence interval (CI) 2.24-5.15, P < .0001}. This association was substantially attenuated when eGFR was added to the model [sHR for log2(pNGAL) 1.63, 95% CI 0.92-2.88, P = .095]. Category-free net reclassification improvement of a risk model including log2(pNGAL) in addition to conventional risk factors and eGFR was 54.3% (95% CI 9.2%-99.3%) but C-statistic did not improve significantly.
    Conclusions: pNGAL was an independent predictor of renal allograft loss in stable KTR from one transplant center but did not show consistent added value when compared with baseline predictors including the conventional marker eGFR. Future studies in larger cohorts are warranted.
    MeSH term(s) Humans ; Acute-Phase Proteins ; Allografts ; Biomarkers ; Kidney Transplantation ; Lipocalin-2 ; Lipocalins ; Proto-Oncogene Proteins
    Chemical Substances Acute-Phase Proteins ; Biomarkers ; Lipocalin-2 ; Lipocalins ; Proto-Oncogene Proteins
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfad226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 329: Show issues

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