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  1. Article: L’alcool et la peau.

    Piérard-Franchimont, C / Nikkels, A F / Piérard, G E

    Revue medicale de Liege

    2019  Volume 74, Issue 5-6, Page(s) 354–359

    Abstract: Cutaneous manifestations related to alcohol intake and abuse are various. Most frequently, there are vascular lesions and cutaneous alterations secondary to hepatic dysfunction. Alcohol consumption represents also a risk factor for many cutaneous ... ...

    Title translation Alcohol and the skin.
    Abstract Cutaneous manifestations related to alcohol intake and abuse are various. Most frequently, there are vascular lesions and cutaneous alterations secondary to hepatic dysfunction. Alcohol consumption represents also a risk factor for many cutaneous diseases, such as psoriasis, where its prevalence is high. Other cutaneous complications associated with alcohol are also discussed.
    MeSH term(s) Alcohol Drinking/adverse effects ; Humans ; Psoriasis/chemically induced ; Risk Factors ; Skin ; Skin Diseases/chemically induced
    Language French
    Publishing date 2019-06-17
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: DERMATOMYCOSES À DERMATOPHYTES.

    Piérard, G E

    Revue medicale de Liege

    2016  Volume 71, Issue 3, Page(s) 147–153

    Abstract: Dermatophytoses are frequent skin diseases. They are caused by anthropophilic, zoophilic or geophilic agents from the Trichophyton, Microsporum and Epidermophyton genus. The clinical aspects distinguish diverse tinea on the scalp, distinct tinea of ... ...

    Title translation Dermatomycoses due to dermatophytes.
    Abstract Dermatophytoses are frequent skin diseases. They are caused by anthropophilic, zoophilic or geophilic agents from the Trichophyton, Microsporum and Epidermophyton genus. The clinical aspects distinguish diverse tinea on the scalp, distinct tinea of glabrous skin corresponding to lesions on the body, face, large folds as well as on palms and soles. Nails are also affected by dermatophytes. According to the involved area, the antifungal treatments are adapted to the nature and location of the fungus.
    MeSH term(s) Antifungal Agents/administration & dosage ; Arthrodermataceae/isolation & purification ; Dermatomycoses/diagnosis ; Dermatomycoses/drug therapy ; Dermatomycoses/microbiology ; Epidermophyton/isolation & purification ; Humans ; Microsporum/isolation & purification ; Tinea/diagnosis ; Tinea/drug therapy ; Tinea/microbiology ; Trichophyton/isolation & purification
    Chemical Substances Antifungal Agents
    Language French
    Publishing date 2016-03
    Publishing country Belgium
    Document type English Abstract ; Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In vitro antimicrobial susceptibility of clinical respiratory isolates to ceftazidime-avibactam and comparators (2016-2018).

    Piérard, D / Stone, G G

    BMC infectious diseases

    2021  Volume 21, Issue 1, Page(s) 600

    Abstract: ... against all subsets of C. koseri and E. coli, and colistin was active against all subsets of P. aeruginosa ...

    Abstract Background: This antimicrobial surveillance study reports in vitro antimicrobial activity and susceptibility data for a panel of agents against respiratory isolates of Enterobacterales and Pseudomonas aeruginosa.
    Methods: Isolates from respiratory specimens were collected in Africa/Middle East, Asia/South Pacific, Europe and Latin America between 2016 and 2018, as part of the Antimicrobial Testing Leadership and Surveillance (ATLAS) program. Broth microdilution methodology was used to quantify minimum inhibitory concentrations, from which rates of susceptibility were determined using EUCAST breakpoints (version 10). Rates of subsets with genes encoding β-lactamases (extended-spectrum β-lactamases [ESBLs], serine carbapenemases and metallo-β-lactamases [MBLs]) were also determined, as well as rates of multidrug-resistant (MDR) P. aeruginosa.
    Results: Among all respiratory Enterobacterales isolates, susceptibility to ceftazidime-avibactam, meropenem, colistin and amikacin was ≥94.4% in each region. For Enterobacterales isolates that were ESBL-positive or carbapenemase-positive/MBL-negative, ceftazidime-avibactam susceptibility was 93.6 and 98.9%, respectively. Fewer than 42.7% of MBL-positive Enterobacterales isolates were susceptible to any agents, except colistin (89.0% susceptible). Tigecycline susceptibility was ≥90.0% among Citrobacter koseri and Escherichia coli isolates, including all β-lactamase-positive subsets. ESBL-positive Enterobacterales were more commonly identified in each region than isolates that were ESBL/carbapenemase-positive; carbapenemase-positive/MBL-negative; or MBL-positive. Among all respiratory P. aeruginosa isolates, the combined susceptibility rates (susceptible at standard dosing regimen plus susceptible at increased exposure) were highest to ceftazidime-avibactam, colistin and amikacin (≥82.4% in each region). Susceptibility to colistin was ≥98.1% for all β-lactamase-positive subsets of P. aeruginosa. The lowest rates of antimicrobial susceptibility were observed among MBL-positive isolates of P. aeruginosa (≤56.6%), with the exception of colistin (100% susceptible). MDR P. aeruginosa were most frequently identified in each region (18.7-28.7%), compared with the subsets of ESBL-positive; carbapenemase-positive/MBL-negative; or MBL-positive isolates.
    Conclusions: Rates of susceptibility among the collections of respiratory Enterobacterales and P. aeruginosa isolates were highest to ceftazidime-avibactam, colistin and amikacin in each region. Tigecycline was active against all subsets of C. koseri and E. coli, and colistin was active against all subsets of P. aeruginosa. The findings of this study indicate the need for continued antimicrobial surveillance among respiratory Gram-negative pathogens, in particular those with genes encoding MBLs.
    MeSH term(s) Amikacin/pharmacology ; Anti-Bacterial Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Bacterial Proteins/genetics ; Ceftazidime/pharmacology ; Citrobacter koseri/drug effects ; Citrobacter koseri/isolation & purification ; Colistin/pharmacology ; Drug Combinations ; Enterobacteriaceae/drug effects ; Enterobacteriaceae/isolation & purification ; Epidemiological Monitoring ; Escherichia coli/drug effects ; Escherichia coli/isolation & purification ; Humans ; Meropenem/pharmacology ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/isolation & purification ; Tigecycline/pharmacology ; beta-Lactamases/genetics
    Chemical Substances Anti-Bacterial Agents ; Azabicyclo Compounds ; Bacterial Proteins ; Drug Combinations ; avibactam, ceftazidime drug combination ; Tigecycline (70JE2N95KR) ; Amikacin (84319SGC3C) ; Ceftazidime (9M416Z9QNR) ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6) ; Meropenem (FV9J3JU8B1) ; Colistin (Z67X93HJG1)
    Language English
    Publishing date 2021-06-23
    Publishing country England
    Document type Journal Article
    ISSN 1471-2334
    ISSN (online) 1471-2334
    DOI 10.1186/s12879-021-06153-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: INFECTIONS CUTANÉES AU COURS DES HÉMOPATHIES MALIGNES.

    Piérard, G E

    Revue medicale de Liege

    2015  Volume 70, Issue 12, Page(s) 617–622

    Abstract: Patients suffering from a malignant hemopathy represent a population at high risk for cutaneous infections that are potentially severe. Viral, bacterial and mycotic infections of the skin are not rare. Their semiology possibly appears falsely reassuring. ...

    Title translation CUTANEOUS INFECTIONS ASSOCIATED WITH HEMATOLOGICAL MALIGNANCIES.
    Abstract Patients suffering from a malignant hemopathy represent a population at high risk for cutaneous infections that are potentially severe. Viral, bacterial and mycotic infections of the skin are not rare. Their semiology possibly appears falsely reassuring. Some skin lesions are primary events. Other lesions are secondary following contiguous extension of another deeper location, or represent a sign of septicemia. Taking care of the patient must be precocious and rigorous.
    MeSH term(s) Hematologic Neoplasms/complications ; Humans ; Immunocompromised Host ; Skin Diseases, Infectious/complications
    Language French
    Publishing date 2015-12
    Publishing country Belgium
    Document type English Abstract ; Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [No title information]

    Piérard, G E / Piérard-Franchimont, C / Nizet, J-L

    Revue medicale de Liege

    2017  Volume 72, Issue 3, Page(s) 113–114

    Title translation L’image du mois Tumeur squamo-mélanocytaire ou matrixome mélanocytaire, un piège diagnostique anatomo-clinique.
    Language French
    Publishing date 2017-03
    Publishing country Belgium
    Document type Case Reports
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [No title information]

    Piérard, G E / Piérard-Franchimont, C

    Revue medicale de Liege

    2017  Volume 72, Issue 2, Page(s) 57

    Title translation L'ulcère artériolosclérotique de Martorell.
    MeSH term(s) Arteriosclerosis/complications ; Humans ; Hypertension/complications ; Leg Ulcer/etiology ; Leg Ulcer/pathology
    Language French
    Publishing date 2017-04-07
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
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  7. Article: L’érythème noueux, une hypodermite aux origines diverses.

    Piérard, G E / Piérard-Franchimont, C

    Revue medicale de Liege

    2017  Volume 72, Issue 1, Page(s) 43–44

    Abstract: Erythema nodosum is an acute nodular panniculitis, mainly affecting young women. Diverse etiologies are evoked, but the most frequent are sarcoidosis (Löfgren syndrome), streptococcal infections, yersiniosis and inflammatory enteropathies. Antalgic drugs ...

    Title translation Erythema nodosum : a panniculitis of diverse origins.
    Abstract Erythema nodosum is an acute nodular panniculitis, mainly affecting young women. Diverse etiologies are evoked, but the most frequent are sarcoidosis (Löfgren syndrome), streptococcal infections, yersiniosis and inflammatory enteropathies. Antalgic drugs and rest are usually adequate in this condition, which is spontaneously of favourable evolution. Treatment of the cause is open to discussion, considering their lack of effect on the evolution of erythema nodosum.
    MeSH term(s) Erythema Nodosum/etiology ; Humans ; Panniculitis/etiology
    Language French
    Publishing date 2017-04-07
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Les syndromes SCAR majeurs.

    Piérard, G E / Lesuisse, M / Piérard-Franchimont, C

    Revue medicale de Liege

    2017  Volume 72, Issue 10, Page(s) 444–447

    Abstract: Some drug eruptions are frequent and follow an indolent course, while others prove to be life-threatening. By contrast, SCAR syndromes are serious skin drug reactions that are rare but their vital prognosis is affected. The three distinct entities of ... ...

    Title translation The major SCAR syndromes.
    Abstract Some drug eruptions are frequent and follow an indolent course, while others prove to be life-threatening. By contrast, SCAR syndromes are serious skin drug reactions that are rare but their vital prognosis is affected. The three distinct entities of importance are the former Lyell's syndrome, now identified as SJS-TEN syndrome (Stevens-Johnson syndrome/toxic epidermal necrolysis), the DRESS syndrome (drug reaction with eosinophilia and systemic symptoms), and the AGEP syndrome (acute generalized exanthematous pustulosis).
    MeSH term(s) Acute Generalized Exanthematous Pustulosis/diagnosis ; Drug Hypersensitivity Syndrome/diagnosis ; Humans ; Stevens-Johnson Syndrome/diagnosis
    Language French
    Publishing date 2017-10
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
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  9. Article: Le Groupe Mosan d’étude des Tumeurs Pigmentaires face au mélanome cutané oligométastatique.

    Piérard, G E / Piérard-Franchimont, C / Delvenne, P

    Revue medicale de Liege

    2017  Volume 72, Issue 6, Page(s) 308–311

    Abstract: The oligometastatic melanoma is a peculiar stage of cancer progression which is initially restricted to the initial body area. In most instances, only a small number of metastases are simultaneously present. The oligometastatic stage is synchronous when ... ...

    Title translation The Mosan Study Group of Pigmented Tumours facing toward the oligometastatic cutaneous melanoma.
    Abstract The oligometastatic melanoma is a peculiar stage of cancer progression which is initially restricted to the initial body area. In most instances, only a small number of metastases are simultaneously present. The oligometastatic stage is synchronous when metastases are disclosed at the time of initial diagnosis of the primary cancer. Metastases are metachronous when they are detected after the initial treatment of the primary neoplasm. A variant of the disease is called the smouldering disease when cutaneous metastases grow or regress in unison. The smouldering disease is granted to a condition when some metastases keep grooving when other metastases regress.
    MeSH term(s) Humans ; Melanoma/pathology ; Skin Neoplasms/pathology ; Melanoma, Cutaneous Malignant
    Language French
    Publishing date 2017-06-19
    Publishing country Belgium
    Document type Classical Article ; English Abstract
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
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  10. Article: La cancérogenèse dans la peau de patients transplantés rénaux.

    Piérard, G E / Piérard-Franchimont, C / Delvenne, P

    Revue medicale de Liege

    2017  Volume 72, Issue 3, Page(s) 146–150

    Abstract: Organ transplants are bound to the induction and upkeep of immunosuppression. The immunomodulatory regimen modalities have changed over time with an improvement of the overage graft survival. The effects are also present on the skin and its ... ...

    Title translation Skin carcinogenesis in renal transplant recipients.
    Abstract Organ transplants are bound to the induction and upkeep of immunosuppression. The immunomodulatory regimen modalities have changed over time with an improvement of the overage graft survival. The effects are also present on the skin and its cancerogenesis which is particularly activated for the squamous cell carcinoma. A review of the recent medical literature reveals the importance of searching squamous cell carcinomas, actinic keratoses, seborrheic keratoses and keratocanthomas before and after organ transplants. The severity of the carcinomas is due to their multiplicity and to the progressive occurrence of more aggressive lesions. Prevention relies on a strict adherence to sun protection after transplantation and on refined immunosuppressive strategies.
    MeSH term(s) Humans ; Immunosuppressive Agents/adverse effects ; Kidney Transplantation ; Skin Neoplasms/etiology ; Transplant Recipients
    Chemical Substances Immunosuppressive Agents
    Language French
    Publishing date 2017-03
    Publishing country Belgium
    Document type Journal Article ; Review
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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