Article ; Online: Cyclobutane-containing alkaloids: origin, synthesis, and biological activities.
The open medicinal chemistry journal
2008 Volume 2, Page(s) 26–37
Abstract: Present review describes research on novel natural cyclobutane-containing alkaloids isolated from terrestrial and marine species. More than 60 biological active compounds have been confirmed to have antimicrobial, antibacterial, antitumor, and other ... ...
| Abstract | Present review describes research on novel natural cyclobutane-containing alkaloids isolated from terrestrial and marine species. More than 60 biological active compounds have been confirmed to have antimicrobial, antibacterial, antitumor, and other activities. The structures, synthesis, origins, and biological activities of a selection of cyclobutane-containing alkaloids are reviewed. With the computer program PASS some additional biological activities are also predicted, which point toward new possible applications of these compounds. This review emphasizes the role of cyclobutane-containing alkaloids as an important source of leads for drug discovery. |
|---|---|
| Language | English |
| Publishing date | 2008-04-15 |
| Publishing country | United Arab Emirates |
| Document type | Journal Article |
| ZDB-ID | 2395968-X |
| ISSN | 1874-1045 ; 1874-1045 |
| ISSN (online) | 1874-1045 |
| ISSN | 1874-1045 |
| DOI | 10.2174/1874104500802010026 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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