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Article: Demographic patterns of walleye (

Davis, Robert P / Simmons, Levi M / Shaw, Stephanie L / Sass, Greg G / Sard, Nicholas M / Isermann, Daniel A / Larson, Wesley A / Homola, Jared J

Evolutionary applications

2024 Volume 17, Issue 3, Page(s) e13665

Abstract: Harvest in ... ...

Abstract	Harvest in walleye
Language	English
Publishing date	2024-03-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2405496-3
ISSN	1752-4563 ; 1752-4571
ISSN (online)	1752-4563
ISSN	1752-4571
DOI	10.1111/eva.13665
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Article ; Online: Firearm suicide risk beliefs and prevention: The role of fear of community violence and firearm ownership for protection.

Lee, Daniel B / Simmons, Megan / Sokol, Rebeccah L / Crimmins, Haley / LaRose, Jessi / Zimmerman, Marc A / Carter, Patrick M

Journal of psychiatric research

2024 Volume 171, Page(s) 340–345

Abstract: Introduction: Household firearm availability is a risk factor for firearm suicide when a household member at-risk for suicide. Firearm ownership for protection and perceptions of community violence may reduce the likelihood of limiting access to ... ...

Abstract	Introduction: Household firearm availability is a risk factor for firearm suicide when a household member at-risk for suicide. Firearm ownership for protection and perceptions of community violence may reduce the likelihood of limiting access to firearms as a way to prevent suicide. The association between a firearm suicide risk belief and the intention to reduce firearm access as a means of preventing suicide, with fear of community violence and firearm ownership for protection as moderators, was examined. Materials and methods: The analytic sample consisted of 388 Missouri firearm owners from a cross-sectional, statewide survey of Missouri adults. Logistic regression models were estimated. Results: Among Missouri firearm owners, firearm suicide risk belief was positively associated with the intention of reducing firearm access for firearm owners who were not afraid of community violence and owned a firearm for non-protection reasons (e.g., hunting). Discussion: Findings suggest that firearm suicide prevention efforts must be tailored to address the underlying beliefs about their violence risk among firearm owners who indicate they principally own for protection.
MeSH term(s)	Adult ; Humans ; Ownership ; Cross-Sectional Studies ; Suicide ; Firearms ; Violence ; Fear
Language	English
Publishing date	2024-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	3148-3
ISSN	1879-1379 ; 0022-3956
ISSN (online)	1879-1379
ISSN	0022-3956
DOI	10.1016/j.jpsychires.2024.01.034
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Article ; Online: Incorporation of Drone Technology Into the Chain of Survival for OHCA: Estimation of Time Needed for Bystander Treatment of OHCA and CPR Performance.

Starks, Monique A / Blewer, Audrey L / Chow, Christine / Sharpe, Edward / Van Vleet, Lee / Arnold, Evan / Buckland, Daniel M / Joiner, Anjni / Simmons, Denise / Green, Cynthia L / Mark, Daniel B

Circulation. Cardiovascular quality and outcomes

2024 Volume 17, Issue 4, Page(s) e010061

Abstract: Background: Drone-delivered automated external defibrillators (AEDs) hold promises in the treatment of out-of-hospital cardiac arrest. Our objective was to estimate the time needed to perform resuscitation with a drone-delivered AED and to measure ... ...

Abstract	Background: Drone-delivered automated external defibrillators (AEDs) hold promises in the treatment of out-of-hospital cardiac arrest. Our objective was to estimate the time needed to perform resuscitation with a drone-delivered AED and to measure cardiopulmonary resuscitation (CPR) quality. Methods: Mock out-of-hospital cardiac arrest simulations that included a 9-1-1 call, CPR, and drone-delivered AED were conducted. Each simulation was timed and video-recorded. CPR performance metrics were recorded by a Laerdal Resusci Anne Quality Feedback System. Multivariable regression modeling examined factors associated with time from 9-1-1 call to AED shock and CPR quality metrics (compression rate, depth, recoil, and chest compression fraction). Comparisons were made among those with recent CPR training (≤2 years) versus no recent (>2 years) or prior CPR training. Results: We recruited 51 research participants between September 2019 and March 2020. The median age was 34 (Q1-Q3, 23-54) years, 56.9% were female, and 41.2% had recent CPR training. The median time from 9-1-1 call to initiation of CPR was 1:19 (Q1-Q3, 1:06-1:26) minutes. A median time of 1:59 (Q1-Q3, 01:50-02:20) minutes was needed to retrieve a drone-delivered AED and deliver a shock. The median CPR compression rate was 115 (Q1-Q3, 109-124) beats per minute, the correct compression depth percentage was 92% (Q1-Q3, 25-98), and the chest compression fraction was 46.7% (Q1-Q3, 39.9%-50.6%). Recent CPR training was not associated with CPR quality or time from 9-1-1 call to AED shock. Younger age (per 10-year increase; β, 9.97 [95% CI, 4.63-15.31] s; Conclusion: Research participants were able to rapidly retrieve an AED from a drone while largely maintaining CPR quality according to American Heart Association guidelines. Chest compression fraction was lower than expected.
MeSH term(s)	Humans ; Female ; Adult ; Male ; Cardiopulmonary Resuscitation ; Out-of-Hospital Cardiac Arrest/diagnosis ; Out-of-Hospital Cardiac Arrest/therapy ; Unmanned Aerial Devices ; Emergency Medical Services ; Electric Countershock/adverse effects ; Defibrillators
Language	English
Publishing date	2024-03-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2483197-9
ISSN	1941-7705 ; 1941-7713
ISSN (online)	1941-7705
ISSN	1941-7713
DOI	10.1161/CIRCOUTCOMES.123.010061
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Article ; Online: Raymond L. Erikson (1936-2020).

Neel, Benjamin G / Sweet, Laurel / Simmons, Daniel L / Blenis, John

Cell

2020 Volume 181, Issue 5, Page(s) 961–963

Language	English
Publishing date	2020-05-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	187009-9
ISSN	1097-4172 ; 0092-8674
ISSN (online)	1097-4172
ISSN	0092-8674
DOI	10.1016/j.cell.2020.04.051
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Article ; Online: Engineered tissue geometry and Plakophilin-2 regulate electrophysiology of human iPSC-derived cardiomyocytes.

Simmons, Daniel W / Malayath, Ganesh / Schuftan, David R / Guo, Jingxuan / Oguntuyo, Kasoorelope / Ramahdita, Ghiska / Sun, Yuwen / Jordan, Samuel D / Munsell, Mary K / Kandalaft, Brennan / Pear, Missy / Rentschler, Stacey L / Huebsch, Nathaniel

APL bioengineering

2024 Volume 8, Issue 1, Page(s) 16118

Abstract: Engineered heart tissues have been created to study cardiac biology and disease in a setting that more closely ... ...

Abstract	Engineered heart tissues have been created to study cardiac biology and disease in a setting that more closely mimics
Language	English
Publishing date	2024-03-11
Publishing country	United States
Document type	Journal Article
ISSN	2473-2877
ISSN (online)	2473-2877
DOI	10.1063/5.0160677
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Article: Antipyretic therapy: clinical pharmacology.

Lee, Jonathan J / Simmons, Daniel L

Handbook of clinical neurology

2018 Volume 157, Page(s) 869–881

Abstract: Fever depends on a complex physiologic response to infectious agents and other conditions. To alleviate fever, many medicinal agents have been developed over a century of trying to improve upon aspirin, which was determined to work by inhibiting ... ...

Abstract	Fever depends on a complex physiologic response to infectious agents and other conditions. To alleviate fever, many medicinal agents have been developed over a century of trying to improve upon aspirin, which was determined to work by inhibiting prostaglandin synthesis. We present the process of fever induction through prostaglandin synthesis and discuss the development of pharmaceuticals that target enzymes and receptors involved in prostaglandin-mediated signal transduction, including prostaglandin H
MeSH term(s)	Animals ; Antipyretics/therapeutic use ; Fever/drug therapy ; Humans ; Pharmacology, Clinical ; Prostaglandins/metabolism ; Signal Transduction/drug effects
Chemical Substances	Antipyretics ; Prostaglandins
Language	English
Publishing date	2018-11-20
Publishing country	Netherlands
Document type	Journal Article ; Review
ISSN	0072-9752
ISSN	0072-9752
DOI	10.1016/B978-0-444-64074-1.00054-9
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Article ; Online: Impacts of long-term application of best management practices on yields and root carbohydrate content in asparagus (Asparagus officinalis) (UK)

Mašková, Lucie / Simmons, Robert W. / Deeks, Lynda K. / De Baets, Sarah / Drost, Daniel T.

European Journal of Agronomy. 2023 July, v. 147 p.126828-

2023

Abstract: Yield physiology of asparagus (Asparagus officinalis L.) is strongly influenced by biotic factors ... determined in 2019 and 2020. BMPs included (1) companion crops - Rye (Secale cereale L.), Mustard ... Sinapis alba L.), (2) interrow surface mulch applications of either straw mulch or PAS 100 compost (Publicly ...

Abstract	Yield physiology of asparagus (Asparagus officinalis L.) is strongly influenced by biotic factors such as crown and root rot caused by Fusarium spp. and by abiotic conditions such as precipitation or temperatures, duration of each harvest, and field management practices. Asparagus yields are linked to the availability of soluble carbohydrates (CHO) in the storage root system which is considered a key factor in asparagus productivity. The aim of this study was to quantify the impacts of the long-term application of a range of potential Best Management Practices (BMPs) on yield and storage root carbohydrate content in green asparagus in a long-term field trial. The trial was established in 2016 with the asparagus 'Gijnlim' variety. Commercial yields were collected in 2018, 2019 and 2020. Root carbohydrate content was determined in 2019 and 2020. BMPs included (1) companion crops - Rye (Secale cereale L.), Mustard (Sinapis alba L.), (2) interrow surface mulch applications of either straw mulch or PAS 100 compost (Publicly available specification) in combination with shallow soil disturbance (SSD), (3) the conventional practice and modifications of the conventional tillage practice by applying SSD or not applying SSD and (4) a zero-tillage option. Annual re-ridging (R) and not ridging (NR) were applied to BMP options 1-3. SSD had no significant impact on asparagus yields while annual re-ridging negatively affected total yields of treatments with bare soil interrows, which were managed without SSD. Conventional practice was associated with a 22% yield reduction and ∼€4250 ha⁻¹ annual loss in potential revenue as compared to the Zero-tillage treatment. Companion cropping with mustard did not have a significant impact on asparagus yields. Rye without annual re-ridging was however associated with yield reductions of > 20% as compared to the Conventional practice. PAS 100 Compost applied in asparagus interrows (at 25 t ha⁻¹ per year) in combination with SSD without annual re-ridging resulted in improvements to yields of 20%, 10% and 34% in 2018, 2019 and 2020, respectively, as compared to the Conventional practice. No correlation was observed between storage root soluble carbohydrate content and asparagus yields. The results of this study confirmed that asparagus yield, and thus total farm income can be significantly improved through implementation of several of the BMPs investigated.
Keywords	Asparagus officinalis ; Fusarium ; Secale cereale ; Sinapis alba ; agronomy ; carbohydrate content ; composts ; conventional tillage ; disturbed soils ; farm income ; field experimentation ; no-tillage ; physiology ; root rot ; root systems ; rye ; straw mulches ; BMP ; SSD ; No-SSD ; R ; NR ; PAS ; CZL ; Asparagus officinalis L. ; Spear weight ; Compost ; Companion crops ; Secale cereale L. ; Root soluble carbohydrate
Language	English
Dates of publication	2023-07
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	1157136-6
ISSN	1873-7331 ; 1161-0301
ISSN (online)	1873-7331
ISSN	1161-0301
DOI	10.1016/j.eja.2023.126828
Database	NAL-Catalogue (AGRICOLA)

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Article: Moving from frugivory to seed dispersal: Incorporating the functional outcomes of interactions in plant–frugivore networks

Simmons, Benno / Sutherland, William / Dicks, Lynn / Albrecht, Jörg / García, Daniel / Jordano, Pedro / González-Varo, Juan P.

Journal of animal ecology, 87(4):995-1007

2018

Abstract: 1. There is growing interest in understanding the functional outcomes of species interactions in ecological networks. For many mutualistic networks, including pollination and seed dispersal networks, interactions are generally sampled by recording animal ...

Institution	Senckenberg Biodiversität und Klima Forschungszentrum
Abstract	1. There is growing interest in understanding the functional outcomes of species interactions in ecological networks. For many mutualistic networks, including pollination and seed dispersal networks, interactions are generally sampled by recording animal foraging visits to plants. However, these visits may not reflect actual pollination or seed dispersal events, despite these typically being the ecological processes of interest. 2. Frugivorous animals can act as seed dispersers, by swallowing entire fruits and dispersing their seeds, or as pulp peckers or seed predators, by pecking fruits to consume pieces of pulp or seeds. These processes have opposing consequences for plant reproductive success. Therefore, equating visitation with seed dispersal could lead to biased inferences about the ecology, evolution and conservation of seed dispersal mutualisms. 3. Here, we use natural history information on the functional outcomes of pairwise bird–plant interactions to examine changes in the structure of seven European plant–frugivore visitation networks after non‐mutualistic interactions (pulp pecking and seed predation) have been removed. Following existing knowledge of the contrasting structures of mutualistic and antagonistic networks, we hypothesized a number of changes following interaction removal, such as increased nestedness and lower specialization. 4. Non‐mutualistic interactions with pulp peckers and seed predators occurred in all seven networks, accounting for 21%–48% of all interactions and 6%–24% of total interaction frequency. When non‐mutualistic interactions were removed, there were significant increases in network‐level metrics such as connectance and nestedness, while robustness decreased. These changes were generally small, homogenous and driven by decreases in network size. Conversely, changes in species‐level metrics were more variable and sometimes large, with significant decreases in plant degree, interaction frequency, specialization and resilience to animal extinctions and significant increases in frugivore species strength. 5. Visitation data can overestimate the actual frequency of seed dispersal services in plant–frugivore networks. We show here that incorporating natural history information on the functions of species interactions can bring us closer to understanding the processes and functions operating in ecological communities. Our categorical approach lays the foundation for future work quantifying functional interaction outcomes along a mutualism–antagonism continuum, as documented in other frugivore faunas.
Keywords	antagonism ; ecological networks ; fleshy fruits ; frugivorous birds ; mutualistic networks ; mutualism ; seed predation ; pulp pecking
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Pharmacists improve diabetes outcomes: a randomized controlled trial.

Wagner, Mary L / McCarthy, Caitlin / Bateman, M Thomas / Simmons, Daniel / Prioli, Katherine M

Journal of the American Pharmacists Association : JAPhA

2021 Volume 62, Issue 3, Page(s) 775–782.e3

Abstract: Background: There is a growing shortage of primary care physicians. Pharmacists can fill the gap, and interdisciplinary teams are being evaluated as part of health care reform.: Objective: This study aimed to determine whether adding a pharmacist to ... ...

Abstract	Background: There is a growing shortage of primary care physicians. Pharmacists can fill the gap, and interdisciplinary teams are being evaluated as part of health care reform. Objective: This study aimed to determine whether adding a pharmacist to an interprofessional health team will improve diabetes outcomes. Methods: In this 2-phase pilot study, Medicaid-eligible patients with diabetes were randomized to receive standard of care (control arm) or standard of care plus the care of a pharmacist (intervention arm) for 12 months (phase 1). The primary outcome was change in glycated hemoglobin (A1C) from baseline. Secondary outcomes included identifying and correcting medication therapy problems (MTPs) for comorbid conditions, adherence to preventive care visits, health care utilization, self-rated health, and satisfaction surveys. After phase 1, patients in the control arm who did not achieve an A1C of < 8% were eligible to enroll into phase 2 where they received treatment with a pharmacist for 6 months. Results: Of the 239 patients enrolled, 122 completed phase 1. At 12 months, intervention patients' mean A1C was 1.85 percentage point (pp) below baseline versus 0.94 pp for control (between-group difference 0.91 pp; P = 0.0218). Most control patients (79%) who completed phase 1 and enrolled into phase 2 improved their A1C by more than 1 pp (P < 0.01). The pharmacists completed 806 patient visits and identified 2638 MTPs. Intervention patients were more adherent to preventive care visits with nutrition (P = 0.043), ophthalmology (P = 0.002), and dentistry (P = 0.007). For intervention patients, 78% rated their experience with the pharmacist as excellent whereas, for control patients, 37% rated their experience with their provider as excellent. Conclusion: Pharmacist comanagement of patients with diabetes can significantly improve glucose control and patient satisfaction. Creative payment models were used to include pharmacists in the interprofessional patient care team.
MeSH term(s)	Diabetes Mellitus, Type 2/drug therapy ; Glycated Hemoglobin A/analysis ; Humans ; Medication Adherence ; Pharmacists ; Pilot Projects
Chemical Substances	Glycated Hemoglobin A
Language	English
Publishing date	2021-12-25
Publishing country	United States
Document type	Clinical Trial, Phase II ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2118585-2
ISSN	1544-3450 ; 1544-3191 ; 1086-5802
ISSN (online)	1544-3450
ISSN	1544-3191 ; 1086-5802
DOI	10.1016/j.japh.2021.12.015
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Article ; Online: Consensus guideline for the diagnosis and management of pituitary adenomas in childhood and adolescence: Part 2, specific diseases.

Korbonits, Márta / Blair, Joanne C / Boguslawska, Anna / Ayuk, John / Davies, Justin H / Druce, Maralyn R / Evanson, Jane / Flanagan, Daniel / Glynn, Nigel / Higham, Claire E / Jacques, Thomas S / Sinha, Saurabh / Simmons, Ian / Thorp, Nicky / Swords, Francesca M / Storr, Helen L / Spoudeas, Helen A

Nature reviews. Endocrinology

2024 Volume 20, Issue 5, Page(s) 290–309

Abstract: Pituitary adenomas are rare in children and young people under the age of 19 (hereafter referred to as CYP) but they pose some different diagnostic and management challenges in this age group than in adults. These rare neoplasms can disrupt maturational, ...

Abstract	Pituitary adenomas are rare in children and young people under the age of 19 (hereafter referred to as CYP) but they pose some different diagnostic and management challenges in this age group than in adults. These rare neoplasms can disrupt maturational, visual, intellectual and developmental processes and, in CYP, they tend to have more occult presentation, aggressive behaviour and are more likely to have a genetic basis than in adults. Through standardized AGREE II methodology, literature review and Delphi consensus, a multidisciplinary expert group developed 74 pragmatic management recommendations aimed at optimizing care for CYP in the first-ever comprehensive consensus guideline to cover the care of CYP with pituitary adenoma. Part 2 of this consensus guideline details 57 recommendations for paediatric patients with prolactinomas, Cushing disease, growth hormone excess causing gigantism and acromegaly, clinically non-functioning adenomas, and the rare TSHomas. Compared with adult patients with pituitary adenomas, we highlight that, in the CYP group, there is a greater proportion of functioning tumours, including macroprolactinomas, greater likelihood of underlying genetic disease, more corticotrophinomas in boys aged under 10 years than in girls and difficulty of peri-pubertal diagnosis of growth hormone excess. Collaboration with pituitary specialists caring for adult patients, as part of commissioned and centralized multidisciplinary teams, is key for optimizing management, transition and lifelong care and facilitates the collection of health-related quality of survival outcomes of novel medical, surgical and radiotherapeutic treatments, which are currently largely missing.
MeSH term(s)	Adult ; Male ; Female ; Humans ; Adolescent ; Child ; Aged ; Pituitary Neoplasms/diagnosis ; Pituitary Neoplasms/therapy ; Pituitary Neoplasms/pathology ; Adenoma/diagnosis ; Adenoma/therapy ; Acromegaly ; Prolactinoma/diagnosis ; Prolactinoma/surgery
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2489381-X
ISSN	1759-5037 ; 1759-5029
ISSN (online)	1759-5037
ISSN	1759-5029
DOI	10.1038/s41574-023-00949-7
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