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  1. Article ; Online: Overinflation of balloon-expandable valves for transcatheter treatment of pure noncalcified native aortic regurgitation: How much oversizing is needed and achievable?

    Orzalkiewicz, Mateusz / Taglieri, Nevio / Palmerini, Tullio / Saia, Francesco

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  

    Abstract: Transcatheter aortic valve implantation (TAVI) in noncalcified pure aortic valve regurgitation is challenging as dedicated valves are not widely available. We present a case series of four inoperable patients who underwent compassionate TAVI for this ... ...

    Abstract Transcatheter aortic valve implantation (TAVI) in noncalcified pure aortic valve regurgitation is challenging as dedicated valves are not widely available. We present a case series of four inoperable patients who underwent compassionate TAVI for this indication at our institution with a balloon-expandable valve. In this context, we analyzed the relevant technical aspects such as the need for larger oversizing of the transcatheter prosthesis and the safety and limits of valve overexpansion.
    Language English
    Publishing date 2022-12-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30529
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  2. Article: Balloon pulmonary angioplasty after pulmonary thromboendarterectomy.

    Palazzini, Massimiliano / Saia, Francesco / Taglieri, Nevio / Guarino, Daniele / Rotunno, Mariangela / Galiѐ, Nazzareno / Dardi, Fabio

    Annals of cardiothoracic surgery

    2022  Volume 11, Issue 2, Page(s) 192–194

    Language English
    Publishing date 2022-03-20
    Publishing country China
    Document type Editorial
    ZDB-ID 2713627-9
    ISSN 2304-1021 ; 2225-319X
    ISSN (online) 2304-1021
    ISSN 2225-319X
    DOI 10.21037/acs-2021-pte-19
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  3. Article ; Online: Tomografia a coerenza ottica e ateromasia dilatativa: l’importanza dell’imaging intracoronarico per ottimizzare il risultato dell’angioplastica.

    Bendandi, Francesco / Ghetti, Gabriele / Taglieri, Nevio

    Giornale italiano di cardiologia (2006)

    2021  Volume 22, Issue 12 Suppl 2, Page(s) 42–44

    Abstract: Percutaneous coronary intervention (PCI) in coronary artery ectasia is technically challenging, particularly regarding appropriate stent sizing, and it is associated with a higher incidence of adverse events. In this case report, a 63-year-old male ... ...

    Title translation Optical coherence tomography and coronary artery ectasia: the critical role of intracoronary imaging for optimal results of percutaneous coronary intervention.
    Abstract Percutaneous coronary intervention (PCI) in coronary artery ectasia is technically challenging, particularly regarding appropriate stent sizing, and it is associated with a higher incidence of adverse events. In this case report, a 63-year-old male patient, heart transplant recipient, underwent elective follow-up coronary angiography in the absence of clinical symptoms. Five years previously the patient was treated with coronary angioplasty and drug-eluting stent implantation for critical lesions of the left anterior descending coronary artery. Angiographic images showed a focal in-stent haziness at the level of an ectatic segment. To elucidate this finding, optical coherence tomography (OCT) was performed. Intracoronary imaging showed severe malapposition of the proximal end of the stent, with an intraluminal signal-rich structure, suggestive of organized stent thrombosis. Stent dilation was performed to maximal recommended diameter, with significant reduction of the malapposed area, as shown by repeated OCT pullbacks. Intracoronary imaging is particularly valuable in PCI of ectatic vessels to guide appropriate stent sizing and avoid stent malapposition. OCT, thanks to its superior spatial resolution in comparison with other intravascular imaging techniques, provides advantages for stent optimization and evaluation of stent failure causes. However, its limited imaging area and possible incomplete blood clearance may limit its usefulness in severely ectatic vessels.
    MeSH term(s) Coronary Vessels/diagnostic imaging ; Dilatation, Pathologic/etiology ; Drug-Eluting Stents ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/methods ; Tomography, Optical Coherence/methods
    Language Italian
    Publishing date 2021-11-01
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2272414-X
    ISSN 1972-6481 ; 1827-6806
    ISSN (online) 1972-6481
    ISSN 1827-6806
    DOI 10.1714/3723.37140
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  4. Article ; Online: The role of the vascular surgeon in transcatheter aortic valve implantation.

    Gallitto, Enrico / Faggioli, Gianluca / Saia, Francesco / Palmerini, Tullio / Pini, Rodolfo / Bruno, Antonio Giulio / Feroldi, Francesca Maria / Alaidros, Moad / Ghetti, Gabriele / Taglieri, Nevio / Caputo, Stefania / Donati, Francesco / Marrozzini, Cinzia / Gargiulo, Mauro

    Vascular

    2024  , Page(s) 17085381241237844

    Abstract: Background: Transcatheter aortic valve implantation (TAVI) has become the standard treatment for severe aortic valve stenosis in patients at increased surgical risk. Percutaneous transfemoral (TF) is the access of choice due to its reduced invasiveness ... ...

    Abstract Background: Transcatheter aortic valve implantation (TAVI) has become the standard treatment for severe aortic valve stenosis in patients at increased surgical risk. Percutaneous transfemoral (TF) is the access of choice due to its reduced invasiveness and perioperative morbidity/mortality compared with the trans-axillary, aortic, and apical routes. On the other hand, vascular access complications (VACs) of the TF access are associated with prolonged hospitalization, 30-day, and 1-year mortality. In addition, the concomitance of peripheral arterial disease may require associated endovascular management. A multidisciplinary team with Interventional Cardiologists and Vascular Surgeons may minimize the rate of VACs in patients with challenging femoral-iliac access or concomitant disease of other vascular districts, thus optimizing the outcome of TF-TAVI. The aim of this study was to evaluate the role of Vascular Surgeons in TF TAVI procedures.
    Methods: We conducted a retrospective single-center review of all TF-TAVI procedures assisted by Vascular Surgeons between January 2016 and December 2020 in a high-volume tertiary hospital. Pre, intra, and postoperative data were analyzed by a dedicated group of Interventional Cardiologists and Vascular Surgeons. VACs were defined according with the Valve Academic Research Consortium (VARC) three guidelines. The outcomes of TF-TAVI procedures with Vascular Surgeons involvement were assessed as study's endpoints.
    Results: Overall, 937 TAVI procedures were performed with a TF approach ranging between 78% (2016) and 98% (2020). Vascular Surgeons were involved in 67 (7%) procedures with the following indications: concomitant abdominal aortic aneurysm (EVAR + TAVI) - 3 (4%), carotid stenosis (TAVI + CAS) - 2 (3%), hostile femoral/iliac access, or VACs - 62 (93%). Balloon angioplasty of iliac artery pre-TAVI implantation was performed in 51 cases (conventional PTA: 38/51%-75%; conventional PTA + intravascular lithotripsy: 13/51%-25%; stenting: 5/51%-10%). TAVI procedure was successfully completed by percutaneous TF approach in all 62 cases with challenging femoral/iliac access. VACs necessitating interventions were 18/937 (2%) cases, localized to the common femoral or common/external iliac artery in 15/18 (83%) and 3/18 (17%) cases, respectively. They were managed by surgical or endovascular maneuvers in 3/18 (17%) and 15/18 (83%) cases, respectively. Fifteen/18 (83%) VACs were treated during the index procedure. There was no procedure-related mortality or 30-day readmission.
    Conclusion: In our experience, Vascular Surgeon assistance in TAVI procedures was not infrequent and allowed safe and effective device introduction through challenging TF access. Similarly, the concomitant significant disease of other vascular districts could be safely addressed, potentially reducing postoperative related mortality and morbidity. The implementation of multidisciplinary team with interventional cardiologists and vascular surgeons should be encouraged whenever possible.
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2137151-9
    ISSN 1708-539X ; 1708-5381
    ISSN (online) 1708-539X
    ISSN 1708-5381
    DOI 10.1177/17085381241237844
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  5. Article ; Online: Successful manual thrombus aspiration in anterior ST-segment elevation myocardial infarction due to cardioembolic obstruction of the left main coronary artery.

    Della Riva, Diego / Bruno, Matteo / Taglieri, Nevio

    Journal of cardiology cases

    2019  Volume 21, Issue 2, Page(s) 46–49

    Abstract: Large clinical trials and meta-analyses have shown that thrombus aspiration (TA) in the setting of ST-T segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) does not improve clinical outcome, whilst ...

    Abstract Large clinical trials and meta-analyses have shown that thrombus aspiration (TA) in the setting of ST-T segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) does not improve clinical outcome, whilst it may be associated with an increased risk of stroke. Accordingly, in the most recent European Society of Cardiology guidelines the role of routine TA during PPCI has been downgraded to a class III recommendation with level A of evidence. On the other hand, it has been suggested that in case of high thrombus burden a selective use of TA may still play a role. STEMI due to cardioembolism (CE) definitely represents one of these situations. In the present case of an 81-year-old woman presenting with STEMI due to a cardioembolic obstruction of left main coronary artery, we show that TA succeeded, whereas classical angioplasty failed, in promoting a prompt coronary flow restoration in a life-threatening condition. Further, it allowed us not to upgrade the procedure with stent implantation that would have required a triple antithrombotic therapy, significantly increasing the bleeding risk. Visual examination of thrombi retrieved suggested the diagnosis of CE. Finally, we clearly show which is the mechanism linking TA with the risk of stroke. <
    Language English
    Publishing date 2019-12-05
    Publishing country Japan
    Document type Case Reports
    ISSN 1878-5409
    ISSN (online) 1878-5409
    DOI 10.1016/j.jccase.2019.06.008
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  6. Article ; Online: Coronary Stent Infection and Subsequent Abscessualization Causing Dislocation in Extravascular Position.

    Bendandi, Francesco / Bruno, Antonio Giulio / Donati, Francesco / Ciurlanti, Leonardo / Orzalkiewicz, Mateusz / Palmerini, Tullio / Marrozzini, Cinzia / Saia, Francesco / Galiè, Nazzareno / Martin Suarez, Sofia / Taglieri, Nevio / Ghetti, Gabriele

    JACC. Cardiovascular interventions

    2022  Volume 15, Issue 16, Page(s) e189–e191

    MeSH term(s) Coronary Artery Bypass ; Coronary Artery Disease ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Stents ; Treatment Outcome
    Language English
    Publishing date 2022-07-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2022.05.048
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  7. Article ; Online: Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation in a Large and Noncalcified Annulus.

    Orzalkiewicz, Mateusz / Bruno, Antonio Giulio / Taglieri, Nevio / Ghetti, Gabriele / Marrozzini, Cinzia / Galiè, Nazzareno / Palmerini, Tullio / Saia, Francesco

    JACC. Cardiovascular interventions

    2021  Volume 14, Issue 19, Page(s) e271–e273

    MeSH term(s) Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Insufficiency/diagnostic imaging ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Heart Valve Prosthesis ; Humans ; Prosthesis Design ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2021-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2021.08.010
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  8. Article ; Online: Coronary ectasia in different scenarios, primarily in myocardial infarction with nonobstructive coronary artery disease.

    Ghetti, Gabriele / Chietera, Francesco / Donati, Francesco / Bendandi, Francesco / Minnucci, Matteo / Bruno, Antonio Giulio / Orzalkiewicz, Mateusz / Nardi, Elena / Palmerini, Tullio / Saia, Francesco / Marrozzini, Cinzia / Galié, Nazzareno / Taglieri, Nevio

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 3, Page(s) 167–171

    Abstract: Aims: Several causes have been reported for coronary artery ectasia (CAE), mostly atherosclerosis and tunica media abnormalities. The main aim of the present study was to investigate if CAE extension differs in distinct clinical settings.: Methods: ... ...

    Abstract Aims: Several causes have been reported for coronary artery ectasia (CAE), mostly atherosclerosis and tunica media abnormalities. The main aim of the present study was to investigate if CAE extension differs in distinct clinical settings.
    Methods: Three hundred and forty-one patients with diagnosis of CAE were identified among 9659 coronary angiographies and divided into four groups according to the patient's admission diagnosis: stable or unstable angina (S-UA), myocardial infarction (MI), aortic disease, aortic valvular disease (AVD). S-UA and MI were subgrouped according to the presence of obstructive coronary artery disease (OCAD). Multivariable logistic regression was used to investigate the relationship between clinical diagnosis and CAE extension as expressed by Markis classification and number of coronary vessels affected by CAE.
    Results: No significant differences in CAE extension were found among the four groups, in terms of vessels affected by CAE (P = 0.37) or Markis class (P = 0.33). CAE was not related to the extension of OCAD as assessed by the Gensini score, which was higher in MI and S-UA groups (P < 0.01). However, when ischemic patients were sub-divided on the basis of the presence of OCAD, MI without obstructive coronary artery disease (MINOCA) was associated with a higher extension of CAE in terms of Markis class 1 (OR 5.08, 95% CI 1.61-16.04; P < 0.01).
    Conclusion: The extension of CAE is comparable in patients referred to coronary angiography for different clinical scenarios, including S-UA, MI, aortic disease, and AVD; however, patients with MINOCA were associated with a higher extension of CAE.Graphical abstract: Difference in coronary artery ectasia extension in terms of Markis class severity, respectively, stratified by clinical presentation and obstructive coronary artery disease presence, http://links.lww.com/JCM/A519.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnostic imaging ; Dilatation, Pathologic ; MINOCA ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/etiology ; Coronary Angiography ; Coronary Vessels/diagnostic imaging ; Coronary Aneurysm
    Language English
    Publishing date 2023-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001445
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  9. Article ; Online: A rescue transcatheter solution for early sutureless basal ring infolding.

    Loforte, Antonio / Comentale, Giuseppe / Coppola, Giuditta / Amodio, Ciro / Botta, Luca / Saia, Francesco / Taglieri, Nevio / Marrozzini, Cinzia / Savini, Carlo / Pacini, Davide

    Journal of cardiac surgery

    2021  Volume 37, Issue 3, Page(s) 697–699

    Abstract: We report the case of an 83-year-old woman treated with a "rescue" valve-in-valve transcatheter aortic valve implantation because of an early basal ring partial collapse of a sutureless valve, probably due to septal hypertrophy. ...

    Abstract We report the case of an 83-year-old woman treated with a "rescue" valve-in-valve transcatheter aortic valve implantation because of an early basal ring partial collapse of a sutureless valve, probably due to septal hypertrophy.
    MeSH term(s) Aged, 80 and over ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Humans ; Transcatheter Aortic Valve Replacement
    Language English
    Publishing date 2021-12-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.16196
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  10. Article ; Online: Predictors of bail-out stenting in patients with small vessel disease treated with drug-coated balloon percutaneous coronary intervention.

    Ghetti, Gabriele / Bendandi, Francesco / Donati, Francesco / Ciurlanti, Leonardo / Nardi, Elena / Bruno, Antonio Giulio / Orzalkiewicz, Mateusz / Palmerini, Tullio / Saia, Francesco / Marrozzini, Cinzia / Galié, Nazzareno / Taglieri, Nevio

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2023  Volume 102, Issue 1, Page(s) 18–24

    Abstract: Background: Drug-coated balloons (DCBs) have shown comparable results with drug-eluting stents in small vessel disease (SVD) percutaneous coronary intervention (PCI) in terms of target vessel revascularization and a reduced incidence of myocardial ... ...

    Abstract Background: Drug-coated balloons (DCBs) have shown comparable results with drug-eluting stents in small vessel disease (SVD) percutaneous coronary intervention (PCI) in terms of target vessel revascularization and a reduced incidence of myocardial infarction. However, the relatively high rate of bail-out stenting (BOS) still represents a major drawback of DCB PCI.
    Aims: The aim of the study was to investigate the clinical, anatomic, and procedural features predictive of BOS after DCB PCI in SVD.
    Methods: We included all consecutive patients undergoing PCI at our institution between January 2020 and May 2022 who were treated with DCB PCI of a de novo lesion in a coronary vessel with a reference vessel diameter (RVD) between 2.0 and 2.5 mm. Angiographic success was defined as a residual stenosis <30% without flow-limiting dissection. Patients who did not meet these criteria underwent BOS.
    Results: A total of 168 consecutive patients and 216 coronary stenoses were included. The rate of bail-out stent was 13.9%. On multivariate analysis, DCB/RVD ratio (odds ratio [OR]: 4.39, 95% confidence interval [CI]: 1.71-11.29, p < 0.01), vessel tortuosity (OR: 7.00, 95% CI: 1.66-29.62, p < 0.01), distal vessel disease (OR: 5.66, 95% CI: 2.02-15.83, p < 0.01), and high complexity (Grade C of ACC/AHA classification) coronary stenoses (OR: 6.31, 95% CI: 1.53-26.04, p = 0.01) were independent predictors of BOS.
    Conclusions: BOS is not an infrequent occurrence in DCB PCI of small vessels and is correlated with vessel tortuosity, distal diffuse vessel disease, higher lesion complexity, and balloon diameter oversizing.
    MeSH term(s) Humans ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/methods ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Coronary Artery Disease/complications ; Angioplasty, Balloon, Coronary/adverse effects ; Treatment Outcome ; Stents/adverse effects ; Vascular Diseases/complications ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/therapy ; Coronary Stenosis/complications ; Coronary Restenosis/etiology ; Coronary Angiography/adverse effects ; Coated Materials, Biocompatible
    Chemical Substances Coated Materials, Biocompatible
    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30688
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