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  1. Article ; Online: From the Editor's Desk.

    Flume, Patrick A

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2022  Volume 21, Issue 2, Page(s) 197–198

    Language English
    Publishing date 2022-03-25
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2022.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6028: Show issues Location:
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  2. Book: Chronic cystic fibrosis respiratory infections

    Flume, Patrick A.

    where do we go from here?

    (Respiratory medicine ; 105, Suppl. 2)

    2011  

    Author's details Patrick A. Flume (guest ed.)
    Series title Respiratory medicine ; 105, Suppl. 2
    Collection
    Language English
    Size S31 S.
    Publisher Elsevier
    Publishing place Kidlington, Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017148863
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Ui III Zs 19 -105,Suppl.2- verfügbar in Königswinter Königswinter

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  3. Article ; Online: The study of CFTR modulators in the very young.

    Flume, Patrick A

    The Lancet. Respiratory medicine

    2019  Volume 7, Issue 4, Page(s) 287–289

    MeSH term(s) Aminophenols ; Aminopyridines ; Benzodioxoles ; Child ; Child, Preschool ; Cystic Fibrosis ; Cystic Fibrosis Transmembrane Conductance Regulator ; Humans ; Quinolones
    Chemical Substances Aminophenols ; Aminopyridines ; Benzodioxoles ; Quinolones ; Cystic Fibrosis Transmembrane Conductance Regulator (126880-72-6) ; ivacaftor (1Y740ILL1Z) ; lumacaftor (EGP8L81APK)
    Language English
    Publishing date 2019-01-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(18)30503-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Nontuberculous mycobacterial pulmonary disease and the potential role of SPR720.

    Winthrop, Kevin L / Flume, Patrick / Hamed, Kamal A

    Expert review of anti-infective therapy

    2023  Volume 21, Issue 11, Page(s) 1177–1187

    Abstract: Introduction: Nontuberculous mycobacteria infect patients who have structural lung disease or those who are immunocompromised. Nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing in prevalence. Treatment guidelines for : Areas ... ...

    Abstract Introduction: Nontuberculous mycobacteria infect patients who have structural lung disease or those who are immunocompromised. Nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing in prevalence. Treatment guidelines for
    Areas covered: SPR720 is a novel therapeutic agent that has demonstrated activity against a range of NTM species, including MAC and MAB. Encouraging
    Expert opinion: Management of NTM-PD is challenging for many reasons including length of therapy, poor efficacy, drug intolerance, recurrence, and resistance development. The current antimicrobial management options for NTM-PD are limited in number and there exists a large unmet need for new treatments. SPR720 has encouraging data that warrant further study in the context of a multidrug regimen.
    MeSH term(s) Humans ; Mycobacterium Infections, Nontuberculous/drug therapy ; Mycobacterium Infections, Nontuberculous/epidemiology ; Mycobacterium Infections, Nontuberculous/microbiology ; Nontuberculous Mycobacteria ; Mycobacterium avium Complex ; Lung Diseases/drug therapy ; Lung Diseases/microbiology ; Anti-Bacterial Agents/adverse effects
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2023.2270158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pulmonary Complications in Cystic Fibrosis: Past, Present, and Future: Adult Cystic Fibrosis Series.

    Mingora, Christina M / Flume, Patrick A

    Chest

    2021  Volume 160, Issue 4, Page(s) 1232–1240

    Abstract: ... ...

    Abstract 1
    MeSH term(s) Antifibrinolytic Agents/therapeutic use ; Bronchoscopy ; Chest Tubes ; Chloride Channel Agonists/therapeutic use ; Cystic Fibrosis/complications ; Cystic Fibrosis/physiopathology ; Cystic Fibrosis/therapy ; Disease Progression ; Hemoptysis/etiology ; Hemoptysis/therapy ; Humans ; Noninvasive Ventilation ; Oxygen Inhalation Therapy ; Palliative Care ; Pleurodesis ; Pneumothorax/etiology ; Pneumothorax/therapy ; Prosthesis Implantation ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; Severity of Illness Index ; Surgical Instruments ; Thoracostomy
    Chemical Substances Antifibrinolytic Agents ; Chloride Channel Agonists
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 349: Show issues

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  6. Article ; Online: The Impact of COVID-19 in Cystic Fibrosis.

    Flume, Patrick A / Saiman, Lisa / Marshall, Bruce

    Archivos de bronconeumologia

    2021  Volume 58, Issue 6, Page(s) 466–468

    MeSH term(s) COVID-19/complications ; Cystic Fibrosis/complications ; Humans
    Language English
    Publishing date 2021-12-17
    Publishing country Spain
    Document type Editorial
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2021.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis.

    Flume, Patrick A

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2016  Volume 15, Issue 2, Page(s) 139–140

    MeSH term(s) Consensus ; Cystic Fibrosis/complications ; Europe ; Humans ; Mycobacterium Infections, Nontuberculous/complications ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium Infections, Nontuberculous/therapy ; Nontuberculous Mycobacteria ; Societies, Medical ; United States
    Language English
    Publishing date 2016-03
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2091075-7
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/S1569-1993(16)00018-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical care for cystic fibrosis: preparing for the future now.

    Konstan, Michael W / Flume, Patrick A

    The Lancet. Respiratory medicine

    2019  Volume 8, Issue 1, Page(s) 10–12

    MeSH term(s) Cystic Fibrosis ; Humans
    Language English
    Publishing date 2019-09-27
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(19)30334-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: JCF Year in Review.

    Flume, Patrick A / Castellani, Carlo / Davies, Jane

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2021  Volume 20, Issue 1, Page(s) 1–2

    MeSH term(s) COVID-19 ; Cystic Fibrosis/therapy ; Delivery of Health Care ; Humans
    Language English
    Publishing date 2021-02-01
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2021.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The impact of switching to race-neutral reference equations on FEV

    Rosenfeld, Margaret / Cromwell, Elizabeth A / Schechter, Michael S / Ren, Clement / Flume, Patrick A / Szczesniak, Rhonda D / Morgan, Wayne J / Jain, Raksha

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2024  

    Abstract: Rationale: The American Thoracic Society recommended switching to race-neutral spirometry reference equations, as race is a social construct and to avoid normalizing disparities in lung function due to structural racism. Understanding the impact of the ... ...

    Abstract Rationale: The American Thoracic Society recommended switching to race-neutral spirometry reference equations, as race is a social construct and to avoid normalizing disparities in lung function due to structural racism. Understanding the impact of the race-neutral equations on percent predicted forced expiratory volume in one second (ppFEV
    Objective(s): To quantify the impact of switching from Global Lung Initiative (GLI) 2012 race-specific to GLI 2022 Global race-neutral reference equations on the distribution of ppFEV
    Methods: Cross-sectional analysis of FEV
    Results: With the switch to GLI Global, ppFEV
    Conclusions: Switching from GLI 2012 race-specific reference equations to GLI 2022 Global race-neutral equations will result in larger reductions in ppFEV
    Language English
    Publishing date 2024-03-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2024.03.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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