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  1. Article: Cystic lymphangioma: A differential diagnosis.

    Joshi, Priya Shirish / Hongal, Bhagyalaxmi / Sanadi, Appasaheb

    Journal of oral and maxillofacial pathology : JOMFP

    2015  Volume 19, Issue 3, Page(s) 393–395

    Language English
    Publishing date 2015-12-18
    Publishing country India
    Document type Case Reports
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/0973-029X.174622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cystic lymphangioma

    Priya Shirish Joshi / Bhagyalaxmi Hongal / Appasaheb Sanadi

    Journal of Oral and Maxillofacial Pathology, Vol 19, Iss 3, Pp 393-

    A differential diagnosis

    2015  Volume 395

    Keywords Dentistry ; RK1-715 ; Medicine ; R ; Surgery ; RD1-811
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: A study of salivary lactate dehydrogenase isoenzyme levels in patients with oral leukoplakia and squamous cell carcinoma by gel electrophoresis method

    Priya Shirish Joshi / Someshwar Golgire

    Journal of Oral and Maxillofacial Pathology, Vol 18, Iss 4, Pp 39-

    2014  Volume 44

    Abstract: Context: The enzyme lactate dehydrogenase (LDH), which is found in almost all the cells of body tissues, can be separated into five fractions and the isoenzyme pattern is believed to vary according to the metabolic requirement of each tissue. LDH ... ...

    Abstract Context: The enzyme lactate dehydrogenase (LDH), which is found in almost all the cells of body tissues, can be separated into five fractions and the isoenzyme pattern is believed to vary according to the metabolic requirement of each tissue. LDH concentration in saliva, as an expression of cellular necrosis, could be considered to be a specific indicator for oral lesions that affect the integrity of the oral mucosa. Aim: The present study was designed to evaluate salivary LDH isoenzyme pattern in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC) and to correlate between LDH isoenzyme levels and histopathologic grading in selected cases of OL and OSCC. Materials and Methods: Clinically diagnosed 30 cases each of OL and OSCC were selected for the study and 30 healthy individuals of comparable age served as control. Unstimulated whole saliva was aseptically collected and was processed immediately for LDH isoenzymes measurement by agarose gel electrophoresis. Biopsy specimen obtained was processed and stained by hematoxylin and eosin. Sections of OL and OSCC cases were scrutinized histopathologically and appropriately graded for epithelial dysplasia and differentiation of carcinoma respectively. Statistical Analysis Used: Two sample t test for testing the significance of difference between two group means was used. Results and Conclusion: The present salivary analysis for LDH isoenzyme reveals an overall increased salivary LDH isoenzyme level in OL and OSCC cases and a significant correlation between levels of salivary LDH isoenzymes and histopathologic grades of dysplasia in OL and OSCC. Salivary analysis of LDH will definitely provide the clinician and/or the patient himself with an efficient, non invasive and friendly new tool for diagnosis and monitoring of oral precancer and cancer.
    Keywords Lactate dehydrogenase enzyme ; oral leukoplakia ; oral squamous cell carcinoma ; saliva ; Dentistry ; RK1-715 ; Medicine ; R ; Surgery ; RD1-811
    Subject code 616
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: A study of salivary lactate dehydrogenase isoenzyme levels in patients with oral leukoplakia and squamous cell carcinoma by gel electrophoresis method.

    Joshi, Priya Shirish / Golgire, Someshwar

    Journal of oral and maxillofacial pathology : JOMFP

    2014  Volume 18, Issue Suppl 1, Page(s) S39–44

    Abstract: Context: The enzyme lactate dehydrogenase (LDH), which is found in almost all the cells of body tissues, can be separated into five fractions and the isoenzyme pattern is believed to vary according to the metabolic requirement of each tissue. LDH ... ...

    Abstract Context: The enzyme lactate dehydrogenase (LDH), which is found in almost all the cells of body tissues, can be separated into five fractions and the isoenzyme pattern is believed to vary according to the metabolic requirement of each tissue. LDH concentration in saliva, as an expression of cellular necrosis, could be considered to be a specific indicator for oral lesions that affect the integrity of the oral mucosa.
    Aim: The present study was designed to evaluate salivary LDH isoenzyme pattern in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC) and to correlate between LDH isoenzyme levels and histopathologic grading in selected cases of OL and OSCC.
    Materials and methods: Clinically diagnosed 30 cases each of OL and OSCC were selected for the study and 30 healthy individuals of comparable age served as control. Unstimulated whole saliva was aseptically collected and was processed immediately for LDH isoenzymes measurement by agarose gel electrophoresis. Biopsy specimen obtained was processed and stained by hematoxylin and eosin. Sections of OL and OSCC cases were scrutinized histopathologically and appropriately graded for epithelial dysplasia and differentiation of carcinoma respectively.
    Statistical analysis used: Two sample t test for testing the significance of difference between two group means was used.
    Results and conclusion: The present salivary analysis for LDH isoenzyme reveals an overall increased salivary LDH isoenzyme level in OL and OSCC cases and a significant correlation between levels of salivary LDH isoenzymes and histopathologic grades of dysplasia in OL and OSCC. Salivary analysis of LDH will definitely provide the clinician and/or the patient himself with an efficient, non invasive and friendly new tool for diagnosis and monitoring of oral precancer and cancer.
    Language English
    Publishing date 2014-10-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/0973-029X.141342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Proliferative Verrucous Leukoplakia

    Bhagyalaxmi Hongal / Priya Shirish Joshi / Appasaheb Sanadi

    Journal of Interdisciplinary Histopathology, Vol 4, Iss 4, Pp 110-

    A Case Report with Emphasis on Diagnosis and Treatment

    2016  Volume 113

    Abstract: Proliferative verrucous leukoplakia (PVL) is characterized by development of multiple keratotic plaques with roughened surface projections. Since its introduction in 1985 by Hansen et al., PVL of the oral mucosa still remains an enigma and is difficult ... ...

    Abstract Proliferative verrucous leukoplakia (PVL) is characterized by development of multiple keratotic plaques with roughened surface projections. Since its introduction in 1985 by Hansen et al., PVL of the oral mucosa still remains an enigma and is difficult to define as a sub-entity of leukoplakia. Although the lesion typically begins as simple, flat hyperkeratosis indistinguishable from ordinary leukoplakic lesion, PVL exhibits persistent growth and eventually becomes exophytic and verrucous in nature. As the lesion progresses, they may go through a stage indistinguishable from verrucous carcinoma but may later develop dysplastic changes or transform into full-fledged squamous cell carcinoma usually within 8 years of initial PVL diagnosis. PVL is unusual among the leukoplakia variants in having a strong female predilection and minimal association with tobacco usage. Presenting here, a case of PVL transforming into verrucous carcinoma with areas of suspected malignancy in a 53-year-old male with habit of chewing tobacco quid and beedi smoking 4-6 times a day since 20 years, with a chief complaint of pain and burning sensation of the oral cavity and multiple oral lesions for 1 month. This paper will elaborate typical behavior pattern of the lesion and will discuss this rare entity in light of current information. [J Interdiscipl Histopathol 2016; 4(4.000): 110-113]
    Keywords Leukoplakia ; Oral cancer ; Proliferative verrucous leukoplakia ; Squamous cell carcinoma ; Verrucous carcinoma ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2016-12-01T00:00:00Z
    Publisher eJManager Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: A histochemical study of tissue eosinophilia in oral squamous cell carcinoma using Congo red staining.

    Joshi, Priya Shirish / Kaijkar, Manasi S

    Dental research journal

    2013  Volume 10, Issue 6, Page(s) 784–789

    Abstract: Background: Tumor associated tissue eosinophilia is believed to play a significant role in the biological behavior of the carcinoma. Eosinophil infiltrate in association with the head and neck squamous cell carcinoma (SCC) have been reviewed from time- ... ...

    Abstract Background: Tumor associated tissue eosinophilia is believed to play a significant role in the biological behavior of the carcinoma. Eosinophil infiltrate in association with the head and neck squamous cell carcinoma (SCC) have been reviewed from time-to-time. The significance of such an association has been variably thought to be either a potential diagnostic tool for stromal invasion or as a prognostic indicator. We aimed to evaluate the efficacy of Congo red staining to differentiate eosinophils in the inflammatory infiltrate in oral squamous cell carcinoma (OSCC) and whether this eosinophilia is associated with the histologic grading in OSCC.
    Materials and methods: The eosinophil infiltration in hematoxylin and eosin (H and E) and Congo red stained sections of 50 biopsies of OSCC were examined. The eosinophil distribution was quantitatively evaluated in both sections as either diffuse or focal and scored as mild, moderate and severe grades. The average number of eosinophils obtained in OSCC stained by H and E and Congo red were then statistically compared by univariate analysis carried out using Student's t-test. P < 0.01 was used to determine the statistical significance.
    Results: In the OSCC, the eosinophil infiltration was seen in 43 out of 50 (86%) cases. The elevation of eosinophil count was more diffuse than focal (36 vs. 7 [83.72 vs. 16.27%]). The staining efficacy of Congo red stain over H and E stain to differentiate eosinophils was excellent and found to be statistically significant (P < 0.01). No significant correlation was found with the eosinophil infiltration and the histologic grades of OSCC.
    Conclusion: Our study showed a strong infiltration of eosinophils in OSCC though no significant correlation was found with the eosinophil infiltration and the histologic grades of OSCC. Congo red staining showed a high sensitivity in staining eosinophils over routine H and E. This staining technique could therefore provide an adjunct to routine H and E in evaluating eosinophils in dysplasia and OSCC cases.
    Language English
    Publishing date 2013-11-27
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2418290-4
    ISSN 2008-0255 ; 1735-3327
    ISSN (online) 2008-0255
    ISSN 1735-3327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Role of HPV-16 in Pathogenesis of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma and Correlation of p16INK4A Expression in HPV-16 Positive Cases

    Gaurav Pralhad Agrawal / Priya Shirish Joshi / Anshita Agrawal

    ISRN Pathology , Vol

    An Immunohistochemical Study

    2013  Volume 2013

    Keywords Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher International Scholarly Research Network
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Ultrasonography - A diagnostic modality for oral and maxillofacial diseases

    Priya Shirish Joshi / Jaydeep Pol / Ahale Sumeet Sudesh

    Contemporary Clinical Dentistry, Vol 5, Iss 3, Pp 345-

    2014  Volume 351

    Abstract: Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance ... ...

    Abstract Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance imaging, and nuclear medicine methods such as positron emission tomography. Of these modalities, USG is easy to-use for the detection of non-invasive and soft tissue related diseases in oral and maxillofacial regions. USG plays an important role in analyzing normal and abnormal structures. In particular, in oral and maxillofacial regions, the USG may be clinically applied to evaluate lymph nodes, subcutaneous, and oral cavity-related diseases. Aims: The aim was to correlate the findings of USG and histopathology for the diagnosis of oral and maxillofacial pathology and to evaluate whether USG can be used as an adjunct in diagnosing oral and maxillofacial pathology. Materials and Methods: A total of 10 clinically diagnosed patients with intraoral cancerous growths, swellings in maxillary and neck region were included in this study. Incision biopsy was obtained for confirming provisional clinical diagnosis. The selected cases were advised USG. All patients were then posted either for hemi-glossectomy, hemi-mandibulectomy, and partial maxillectomy with or without radical neck dissection. Statistical Analysis: Student′s t-test and coefficient of correlation was used to statistically analyze significant relationship of both the methods. Result: In all 10 cases, USG correlated well with histopathology findings, it could also delineate tumor extent and measure tumor thickness. Conclusion: USG is an excellent method for the diagnosis of soft tissue lesions and can be used as an adjunct in diagnosing oral and maxillofacial pathology.
    Keywords Histopathology ; lymph node ; metastasis ; squamous cell carcinoma ; tumor thickness ; ultrasonography ; Dentistry ; RK1-715 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article ; Online: Ultrasonography - A diagnostic modality for oral and maxillofacial diseases

    Priya Shirish Joshi / Jaydeep Pol / Ahale Sumeet Sudesh

    Contemporary Clinical Dentistry, Vol 5, Iss 3, Pp 345-

    2014  Volume 351

    Abstract: Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance ... ...

    Abstract Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance imaging, and nuclear medicine methods such as positron emission tomography. Of these modalities, USG is easy to-use for the detection of non-invasive and soft tissue related diseases in oral and maxillofacial regions. USG plays an important role in analyzing normal and abnormal structures. In particular, in oral and maxillofacial regions, the USG may be clinically applied to evaluate lymph nodes, subcutaneous, and oral cavity-related diseases. Aims: The aim was to correlate the findings of USG and histopathology for the diagnosis of oral and maxillofacial pathology and to evaluate whether USG can be used as an adjunct in diagnosing oral and maxillofacial pathology. Materials and Methods: A total of 10 clinically diagnosed patients with intraoral cancerous growths, swellings in maxillary and neck region were included in this study. Incision biopsy was obtained for confirming provisional clinical diagnosis. The selected cases were advised USG. All patients were then posted either for hemi-glossectomy, hemi-mandibulectomy, and partial maxillectomy with or without radical neck dissection. Statistical Analysis: Student′s t-test and coefficient of correlation was used to statistically analyze significant relationship of both the methods. Result: In all 10 cases, USG correlated well with histopathology findings, it could also delineate tumor extent and measure tumor thickness. Conclusion: USG is an excellent method for the diagnosis of soft tissue lesions and can be used as an adjunct in diagnosing oral and maxillofacial pathology.
    Keywords Histopathology ; lymph node ; metastasis ; squamous cell carcinoma ; tumor thickness ; ultrasonography ; Dentistry ; RK1-715 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  10. Article: Ultrasonography - A diagnostic modality for oral and maxillofacial diseases.

    Joshi, Priya Shirish / Pol, Jaydeep / Sudesh, Ahale Sumeet

    Contemporary clinical dentistry

    2014  Volume 5, Issue 3, Page(s) 345–351

    Abstract: Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance ... ...

    Abstract Background: Many diseases present themselves in oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intraoral and panoramic radiography, ultrasonography (USG), computer tomography, magnetic resonance imaging, and nuclear medicine methods such as positron emission tomography. Of these modalities, USG is easy to-use for the detection of non-invasive and soft tissue related diseases in oral and maxillofacial regions. USG plays an important role in analyzing normal and abnormal structures. In particular, in oral and maxillofacial regions, the USG may be clinically applied to evaluate lymph nodes, subcutaneous, and oral cavity-related diseases.
    Aims: The aim was to correlate the findings of USG and histopathology for the diagnosis of oral and maxillofacial pathology and to evaluate whether USG can be used as an adjunct in diagnosing oral and maxillofacial pathology.
    Materials and methods: A total of 10 clinically diagnosed patients with intraoral cancerous growths, swellings in maxillary and neck region were included in this study. Incision biopsy was obtained for confirming provisional clinical diagnosis. The selected cases were advised USG. All patients were then posted either for hemi-glossectomy, hemi-mandibulectomy, and partial maxillectomy with or without radical neck dissection.
    Statistical analysis: Student's t-test and coefficient of correlation was used to statistically analyze significant relationship of both the methods.
    Result: In all 10 cases, USG correlated well with histopathology findings, it could also delineate tumor extent and measure tumor thickness.
    Conclusion: USG is an excellent method for the diagnosis of soft tissue lesions and can be used as an adjunct in diagnosing oral and maxillofacial pathology.
    Language English
    Publishing date 2014-06-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 2582352-8
    ISSN 0976-2361 ; 0976-237X
    ISSN (online) 0976-2361
    ISSN 0976-237X
    DOI 10.4103/0976-237X.137942
    Database MEDical Literature Analysis and Retrieval System OnLINE

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