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  1. Book ; Online: First Measurement of the $\Lambda_c^+ \to p \eta'$ decay

    Belle Collaboration / Li, S. X. / Cui, J. X. / Shen, C. P. / Adachi, I. / Aihara, H. / Said, S. Al / Asner, D. M. / Atmacan, H. / Aushev, T. / Ayad, R. / Babu, V. / Behera, P. / Belous, K. / Bessner, M. / Bhardwaj, V. / Bhuyan, B. / Bilka, T. / Bodrov, D. /
    Bonvicini, G. / Borah, J. / Bozek, A. / Bracko, M. / Branchini, P. / Browder, T. E. / Budano, A. / Campajola, M. / Cervenkov, D. / Chang, M. -C. / Chang, P. / Chekelian, V. / Chen, A. / Cheon, B. G. / Chilikin, K. / Cho, H. E. / Cho, K. / Cho, S. -J. / Choi, S. -K. / Choi, Y. / Choudhury, S. / Cinabro, D. / Cunliffe, S. / Das, S. / Dash, N. / De Nardo, G. / De Pietro, G. / Dhamija, R. / Di Capua, F. / Dolezal, Z. / Dong, T. V. / Epifanov, D. / Ferber, T. / Ferlewicz, D. / Fulsom, B. G. / Garg, R. / Gaur, V. / Gabyshev, N. / Giri, A. / Goldenzweig, P. / Golob, B. / Graziani, E. / Gu, T. / Hara, T. / Hayasaka, K. / Hayashii, H. / Hou, W. -S. / Inami, K. / Ishikawa, A. / Iwasaki, M. / Iwasaki, Y. / Jacobs, W. W. / Jang, E. -J. / Jia, S. / Jin, Y. / Joo, K. K. / Kahn, J. / Kaliyar, A. B. / Kang, K. H. / Kato, Y. / Kawasaki, T. / Kichimi, H. / Kiesling, C. / Kim, C. H. / Kim, D. Y. / Kim, Y. -K. / Kinoshita, K. / Kodys, P. / Konno, T. / Korobov, A. / Korpar, S. / Kovalenko, E. / Krizan, P. / Kroeger, R. / Krokovny, P. / Kumar, M. / Kumar, R. / Kumara, K. / Kwon, Y. -J. / Lam, T. / Laurenza, M. / Lee, S. C. / Li, J. / Li, L. K. / Li, Y. / Gioi, L. Li / Libby, J. / Liventsev, D. / Martini, A. / Masuda, M. / Matsuda, T. / Matvienko, D. / Maurya, S. K. / Meier, F. / Merola, M. / Miyabayashi, K. / Mizuk, R. / Mussa, R. / Nakao, M. / Narwal, D. / Natkaniec, Z. / Natochii, A. / Nayak, L. / Nisar, N. K. / Nishida, S. / Nishimura, K. / Ogawa, K. / Ogawa, S. / Ono, H. / Oskin, P. / Pakhlov, P. / Pakhlova, G. / Pang, T. / Pardi, S. / Park, S. -H. / Patra, S. / Pedlar, T. K. / Pestotnik, R. / Piilonen, L. E. / Podobnik, T. / Popov, V. / Prim, M. T. / Rohrken, M. / Rostomyan, A. / Rout, N. / Russo, G. / Sahoo, D. / Sandilya, S. / Sangal, A. / Sanuki, T. / Savinov, V. / Schnell, G. / Schueler, J. / Schwanda, C. / Schwartz, A. J. / Seino, Y. / Senyo, K. / Sevior, M. E. / Shapkin, M. / Sharma, C. / Shebalin, V. / Shiu, J. -G. / Shwartz, B. / Simon, F. / Solovieva, E. / Stanic, S. / Staric, M. / Stottler, Z. S. / Sumihama, M. / Sumisawa, K. / Sumiyoshi, T. / Sutcliffe, W. / Takizawa, M. / Tamponi, U. / Tanida, K. / Tenchini, F. / Trabelsi, K. / Uchida, M. / Unno, Y. / Uno, K. / Uno, S. / Urquijo, P. / Vahsen, S. E. / Van Tonder, R. / Varner, G. / Vinokurova, A. / Waheed, E. / Wang, D. / Wang, E. / Wang, M. -Z. / Watanuki, S. / Won, E. / Xu, X. / Yabsley, B. D. / Yan, W. / Ye, H. / Yin, J. H. / Yusa, Y. / Zhai, Y. / Zhilich, V. / Zhukova, V.

    2021  

    Abstract: ... decay $\Lambda_c^+ \to p \eta'$ with $\eta' \to \eta\pi^+\pi^-$, using a data sample corresponding ... _c^+ \to pK^-\pi^+$ is measured to be \begin{equation*} \frac{{\cal B}(\Lambda_c^+ \to p \eta')}{{\cal ... B}(\Lambda_c^+ \to p K^-\pi^+)} = (7.54 \pm 1.32 \pm 0.75) \times 10^{-3}, \end{equation ...

    Abstract We present the first measurement of the branching fraction of the singly Cabibbo-suppressed (SCS) decay $\Lambda_c^+ \to p \eta'$ with $\eta' \to \eta\pi^+\pi^-$, using a data sample corresponding to an integrated luminosity of 981 $\rm fb^{-1}$, collected by the Belle detector at the KEKB $e^{+}$$e^{-}$ asymmetric-energy collider. A significant $\Lambda_c^+$ signal is observed for the first time with a signal significance of 5.4$\sigma$. The relative branching fraction with respect to the normalization mode $\Lambda_c^+ \to pK^-\pi^+$ is measured to be \begin{equation*} \frac{{\cal B}(\Lambda_c^+ \to p \eta')}{{\cal B}(\Lambda_c^+ \to p K^-\pi^+)} = (7.54 \pm 1.32 \pm 0.75) \times 10^{-3}, \end{equation*} where the uncertainties are statistical and systematic, respectively. Using the world-average value of ${\cal B}(\Lambda_c^+ \to p K^-\pi^+) = (6.28\pm0.32)\times10^{-2}$, we obtain \begin{equation*} {\cal B}(\Lambda_c^+ \to p \eta') = (4.73 \pm 0.82 \pm 0.47 \pm 0.24)\times 10^{-4}, \end{equation*} where the uncertainties are statistical, systematic, and from ${\cal B}(\Lambda_c^+ \to pK^-\pi^+)$, respectively.

    Comment: 14 pages, 2 figures, accepted for publication in JHEP
    Keywords High Energy Physics - Experiment ; High Energy Physics - Phenomenology
    Subject code 551
    Publishing date 2021-12-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Adduct-based p-doping of organic semiconductors.

    Sakai, Nobuya / Warren, Ross / Zhang, Fengyu / Nayak, Simantini / Liu, Junliang / Kesava, Sameer V / Lin, Yen-Hung / Biswal, Himansu S / Lin, Xin / Grovenor, Chris / Malinauskas, Tadas / Basu, Aniruddha / Anthopoulos, Thomas D / Getautis, Vytautas / Kahn, Antoine / Riede, Moritz / Nayak, Pabitra K / Snaith, Henry J

    Nature materials

    2021  Volume 20, Issue 9, Page(s) 1248–1254

    Abstract: ... we report dimethyl sulfoxide adducts as p-dopants that fulfil these conditions for a range of organic ... of counterion. We demonstrate that asymmetric p-doping is possible using solution processing routes, and ...

    Abstract Electronic doping of organic semiconductors is essential for their usage in highly efficient optoelectronic devices. Although molecular and metal complex-based dopants have already enabled significant progress of devices based on organic semiconductors, there remains a need for clean, efficient and low-cost dopants if a widespread transition towards larger-area organic electronic devices is to occur. Here we report dimethyl sulfoxide adducts as p-dopants that fulfil these conditions for a range of organic semiconductors. These adduct-based dopants are compatible with both solution and vapour-phase processing. We explore the doping mechanism and use the knowledge we gain to 'decouple' the dopants from the choice of counterion. We demonstrate that asymmetric p-doping is possible using solution processing routes, and demonstrate its use in metal halide perovskite solar cells, organic thin-film transistors and organic light-emitting diodes, which showcases the versatility of this doping approach.
    Language English
    Publishing date 2021-04-22
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-021-00980-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Low Resistance Ohmic Contact to P-type Monolayer WSe2

    Xie, Jingxu / Zhang, Zuocheng / Zhang, Haodong / Nagarajan, Vikram / Zhao, Wenyu / Kim, Haleem / Sanborn, Collin / Qi, Ruishi / Chen, Sudi / Kahn, Salman / Watanabe, Kenji / Taniguchi, Takashi / Zettl, Alex / Crommie, Michael / Analytis, James / Wang, Feng

    2023  

    Abstract: ... challenge for achieving high-performance 2D semiconductor field effect transistors (FET), especially for p ... not work for p-type 2D semiconductors such as monolayer tungsten diselenide (WSe$_2$).In this study ... low-resistance ohmic contact for p-type WSe$_2$ transistors. We show that a hole doping as high as 3$ ...

    Abstract Advanced microelectronics in the future may require semiconducting channel materials beyond silicon. Two-dimensional (2D) semiconductors, characterized by their atomically thin thickness, hold immense promise for high-performance electronic devices at the nanometer scale with lower heat dissipation. One challenge for achieving high-performance 2D semiconductor field effect transistors (FET), especially for p-type materials, is the high electrical contact resistance present at the metal-semiconductor interface. In conventional bulk semiconductors, low resistance ohmic contact is realized through heavy substitutional doping with acceptor or donor impurities at the contact region. The strategy of substitutional doping, however, does not work for p-type 2D semiconductors such as monolayer tungsten diselenide (WSe$_2$).In this study, we developed highly efficient charge-transfer doping with WSe$_2$/$\alpha$-RuCl$_3$ heterostructures to achieve low-resistance ohmic contact for p-type WSe$_2$ transistors. We show that a hole doping as high as 3$\times$10$^{13}$ cm$^{-2}$ can be achieved in the WSe$_2/\alpha$-RuCl$_3$ heterostructure due to its type-III band alignment. It results in an Ohmic contact with resistance lower than 4 k Ohm $\mu$m at the p-type monolayer WSe$_2$/metal junction. at room temperature. Using this low-resistance contact, we demonstrate high-performance p-type WSe$_2$ transistors with a saturation current of 35 $\mu$A$\cdot$ $\mu$m$^{-1}$ and an I$_{ON}$/I$_{OFF}$ ratio exceeding 10$^9$ It could enable future microelectronic devices based on 2D semiconductors and contribute to the extension of Moore's law.
    Keywords Condensed Matter - Mesoscale and Nanoscale Physics ; Condensed Matter - Materials Science
    Subject code 621
    Publishing date 2023-12-08
    Publishing country us
    Document type Book ; Online
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  4. Article ; Online: Nanocrystal-ligand interactions deciphered: the influence of HSAB and p

    Champouret, Yohan / Spataro, Grégory / Coppel, Yannick / Gauffre, Fabienne / Kahn, Myrtil L

    Nanoscale advances

    2020  Volume 2, Issue 3, Page(s) 1046–1053

    Abstract: ... interactions. Analysis of the results using p ...

    Abstract Despite all the efforts made by the scientific community to rationalize the interaction of organic molecules with nanocrystals (Ncs), we are still at the level of the empirical recipe when the material behavior in solution is concerned. In an effort to address this issue, the analysis of the luminescence measurements of ZnO Ncs in the presence of various organic substrates using a Langmuir adsorption model was carried out to determine for the first time the affinity constants and the number of binding sites as well as to rank the interaction strengths of these substrates with regard to ZnO Ncs. The results were confirmed by NMR spectroscopic studies, which, besides, provided a deep understanding of the substrate-ZnO Nc interactions. Analysis of the results using p
    Language English
    Publishing date 2020-02-17
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/c9na00769e
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  5. Article ; Online: (with research data) The extent and consequences of p-hacking in science.

    Head, Megan L / Holman, Luke / Lanfear, Rob / Kahn, Andrew T / Jennions, Michael D

    PLoS biology

    2015  Volume 13, Issue 3, Page(s) e1002106

    Abstract: ... in the scientific literature. One type of bias, known as "p-hacking," occurs when researchers collect or select data ... to demonstrate that p-hacking is widespread throughout science. We then illustrate how one can test for p-hacking ... when performing a meta-analysis and show that, while p-hacking is probably common, its effect seems to be weak ...

    Abstract A focus on novel, confirmatory, and statistically significant results leads to substantial bias in the scientific literature. One type of bias, known as "p-hacking," occurs when researchers collect or select data or statistical analyses until nonsignificant results become significant. Here, we use text-mining to demonstrate that p-hacking is widespread throughout science. We then illustrate how one can test for p-hacking when performing a meta-analysis and show that, while p-hacking is probably common, its effect seems to be weak relative to the real effect sizes being measured. This result suggests that p-hacking probably does not drastically alter scientific consensuses drawn from meta-analyses.
    MeSH term(s) Humans ; Meta-Analysis as Topic ; Publication Bias ; Science/ethics ; Science/statistics & numerical data ; Statistics as Topic
    Language English
    Publishing date 2015-03-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.1002106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Measurement of multi-particle azimuthal correlations in pp, p + Pb and low-multiplicity Pb + Pb collisions with the ATLAS detector.

    Aaboud, M / Aad, G / Abbott, B / Abdallah, J / Abdinov, O / Abeloos, B / Abidi, S H / AbouZeid, O S / Abraham, N L / Abramowicz, H / Abreu, H / Abreu, R / Abulaiti, Y / Acharya, B S / Adachi, S / Adamczyk, L / Adelman, J / Adersberger, M / Adye, T /
    Affolder, A A / Agatonovic-Jovin, T / Agheorghiesei, C / Aguilar-Saavedra, J A / Ahlen, S P / Ahmadov, F / Aielli, G / Akatsuka, S / Akerstedt, H / Åkesson, T P A / Akimov, A V / Alberghi, G L / Albert, J / Albicocco, P / Verzini, M J Alconada / Aleksa, M / Aleksandrov, I N / Alexa, C / Alexander, G / Alexopoulos, T / Alhroob, M / Ali, B / Aliev, M / Alimonti, G / Alison, J / Alkire, S P / Allbrooke, B M M / Allen, B W / Allport, P P / Aloisio, A / Alonso, A / Alonso, F / Alpigiani, C / Alshehri, A A / Alstaty, M / Gonzalez, B Alvarez / Piqueras, D Álvarez / Alviggi, M G / Amadio, B T / Coutinho, Y Amaral / Amelung, C / Amidei, D / Santos, S P Amor Dos / Amorim, A / Amoroso, S / Amundsen, G / Anastopoulos, C / Ancu, L S / Andari, N / Andeen, T / Anders, C F / Anders, J K / Anderson, K J / Andreazza, A / Andrei, V / Angelidakis, S / Angelozzi, I / Angerami, A / Anisenkov, A V / Anjos, N / Annovi, A / Antel, C / Antonelli, M / Antonov, A / Antrim, D J / Anulli, F / Aoki, M / Bella, L Aperio / Arabidze, G / Arai, Y / Araque, J P / Ferraz, V Araujo / Arce, A T H / Ardell, R E / Arduh, F A / Arguin, J-F / Argyropoulos, S / Arik, M / Armbruster, A J / Armitage, L J / Arnaez, O / Arnold, H / Arratia, M / Arslan, O / Artamonov, A / Artoni, G / Artz, S / Asai, S / Asbah, N / Ashkenazi, A / Asquith, L / Assamagan, K / Astalos, R / Atkinson, M / Atlay, N B / Augsten, K / Avolio, G / Axen, B / Ayoub, M K / Azuelos, G / Baas, A E / Baca, M J / Bachacou, H / Bachas, K / Backes, M / Backhaus, M / Bagnaia, P / Bahrasemani, H / Baines, J T / Bajic, M / Baker, O K / Baldin, E M / Balek, P / Balli, F / Balunas, W K / Banas, E / Banerjee, Sw / Bannoura, A A E / Barak, L / Barberio, E L / Barberis, D / Barbero, M / Barillari, T / Barisits, M-S / Barklow, T / Barlow, N / Barnes, S L / Barnett, B M / Barnett, R M / Barnovska-Blenessy, Z / Baroncelli, A / Barone, G / Barr, A J / Navarro, L Barranco / Barreiro, F / da Costa, J Barreiro Guimarães / Bartoldus, R / Barton, A E / Bartos, P / Basalaev, A / Bassalat, A / Bates, R L / Batista, S J / Batley, J R / Battaglia, M / Bauce, M / Bauer, F / Bawa, H S / Beacham, J B / Beattie, M D / Beau, T / Beauchemin, P H / Bechtle, P / Beck, H P / Becker, K / Becker, M / Beckingham, M / Becot, C / Beddall, A J / Beddall, A / Bednyakov, V A / Bedognetti, M / Bee, C P / Beermann, T A / Begalli, M / Begel, M / Behr, J K / Bell, A S / Bella, G / Bellagamba, L / Bellerive, A / Bellomo, M / Belotskiy, K / Beltramello, O / Belyaev, N L / Benary, O / Benchekroun, D / Bender, M / Bendtz, K / Benekos, N / Benhammou, Y / Noccioli, E Benhar / Benitez, J / Benjamin, D P / Benoit, M / Bensinger, J R / Bentvelsen, S / Beresford, L / Beretta, M / Berge, D / Kuutmann, E Bergeaas / Berger, N / Beringer, J / Berlendis, S / Bernard, N R / Bernardi, G / Bernius, C / Bernlochner, F U / Berry, T / Berta, P / Bertella, C / Bertoli, G / Bertolucci, F / Bertram, I A / Bertsche, C / Bertsche, D / Besjes, G J / Bylund, O Bessidskaia / Bessner, M / Besson, N / Betancourt, C / Bethani, A / Bethke, S / Bevan, A J / Bianchi, R M / Biebel, O / Biedermann, D / Bielski, R / Biesuz, N V / Biglietti, M / De Mendizabal, J Bilbao / Billoud, T R V / Bilokon, H / Bindi, M / Bingul, A / Bini, C / Biondi, S / Bisanz, T / Bittrich, C / Bjergaard, D M / Black, C W / Black, J E / Black, K M / Blackburn, D / Blair, R E / Blazek, T / Bloch, I / Blocker, C / Blue, A / Blum, W / Blumenschein, U / Blunier, S / Bobbink, G J / Bobrovnikov, V S / Bocchetta, S S / Bocci, A / Bock, C / Boehler, M / Boerner, D / Bogavac, D / Bogdanchikov, A G / Bohm, C / Boisvert, V / Bokan, P / Bold, T / Boldyrev, A S / Bolz, A E / Bomben, M / Bona, M / Boonekamp, M / Borisov, A / Borissov, G / Bortfeldt, J / Bortoletto, D / Bortolotto, V / Boscherini, D / Bosman, M / Sola, J D Bossio / Boudreau, J / Bouffard, J / Bouhova-Thacker, E V / Boumediene, D / Bourdarios, C / Boutle, S K / Boveia, A / Boyd, J / Boyko, I R / Bracinik, J / Brandt, A / Brandt, G / Brandt, O / Bratzler, U / Brau, B / Brau, J E / Madden, W D Breaden / Brendlinger, K / Brennan, A J / Brenner, L / Brenner, R / Bressler, S / Briglin, D L / Bristow, T M / Britton, D / Britzger, D / Brochu, F M / Brock, I / Brock, R / Brooijmans, G / Brooks, T / Brooks, W K / Brosamer, J / Brost, E / Broughton, J H / de Renstrom, P A Bruckman / Bruncko, D / Bruni, A / Bruni, G / Bruni, L S / Brunt, B H / Bruschi, M / Bruscino, N / Bryant, P / Bryngemark, L / Buanes, T / Buat, Q / Buchholz, P / Buckley, A G / Budagov, I A / Buehrer, F / Bugge, M K / Bulekov, O / Bullock, D / Burch, T J / Burckhart, H / Burdin, S / Burgard, C D / Burger, A M / Burghgrave, B / Burka, K / Burke, S / Burmeister, I / Burr, J T P / Busato, E / Büscher, D / Büscher, V / Bussey, P / Butler, J M / Buttar, C M / Butterworth, J M / Butti, P / Buttinger, W / Buzatu, A / Buzykaev, A R / Urbán, S Cabrera / Caforio, D / Cairo, V M / Cakir, O / Calace, N / Calafiura, P / Calandri, A / Calderini, G / Calfayan, P / Callea, G / Caloba, L P / 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C C / Barajas, C A Chavez / Che, S / Cheatham, S / Chegwidden, A / Chekanov, S / Chekulaev, S V / Chelkov, G A / Chelstowska, M A / Chen, C / Chen, H / Chen, S / Chen, X / Chen, Y / Cheng, H C / Cheng, H J / Cheplakov, A / Cheremushkina, E / Moursli, R Cherkaoui El / Chernyatin, V / Cheu, E / Chevalier, L / Chiarella, V / Chiarelli, G / Chiodini, G / Chisholm, A S / Chitan, A / Chiu, Y H / Chizhov, M V / Choi, K / Chomont, A R / Chouridou, S / Christodoulou, V / Chromek-Burckhart, D / Chu, M C / Chudoba, J / Chuinard, A J / Chwastowski, J J / Chytka, L / Ciftci, A K / Cinca, D / Cindro, V / Cioara, I A / Ciocca, C / Ciocio, A / Cirotto, F / Citron, Z H / Citterio, M / Ciubancan, M / Clark, A / Clark, B L / Clark, M R / Clark, P J / Clarke, R N / Clement, C / Coadou, Y / Cobal, M / Coccaro, A / Cochran, J / Colasurdo, L / Cole, B / Colijn, A P / Collot, J / Colombo, T / Muiño, P Conde / Coniavitis, E / Connell, S H / Connelly, I A / Constantinescu, S / Conti, G / Conventi, F / Cooke, M / Cooper-Sarkar, A M / Cormier, F / Cormier, K J R / Corradi, M / Corriveau, F / Cortes-Gonzalez, A / Cortiana, G / Costa, G / Costa, M J / Costanzo, D / Cottin, G / Cowan, G / Cox, B E / Cranmer, K / Crawley, S J / Creager, R A / Cree, G / Crépé-Renaudin, S / Crescioli, F / Cribbs, W A / Cristinziani, M / Croft, V / Crosetti, G / Cueto, A / Donszelmann, T Cuhadar / Cukierman, A R / Cummings, J / Curatolo, M / Cúth, J / Czirr, H / Czodrowski, P / D'amen, G / D'Auria, S / D'Onofrio, M / De Sousa, M J Da Cunha Sargedas / Via, C Da / Dabrowski, W / Dado, T / Dai, T / Dale, O / Dallaire, F / Dallapiccola, C / Dam, M / Dandoy, J R / Dang, N P / Daniells, A C / Dann, N S / Danninger, M / Hoffmann, M Dano / Dao, V / Darbo, G / Darmora, S / Dassoulas, J / Dattagupta, A / Daubney, T / Davey, W / David, C / Davidek, T / Davies, M / Davison, P / Dawe, E / Dawson, I / De, K / de Asmundis, R / De Benedetti, A / De Castro, S / De Cecco, S / De Groot, N / de Jong, P / De la Torre, H / De Lorenzi, F / 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S / Wenaus, T / Wengler, T / Wenig, S / Wermes, N / Werner, M D / Werner, P / Wessels, M / Whalen, K / Whallon, N L / Wharton, A M / White, A S / White, A / White, M J / White, R / Whiteson, D / Wickens, F J / Wiedenmann, W / Wielers, M / Wiglesworth, C / Wiik-Fuchs, L A M / Wildauer, A / Wilk, F / Wilkens, H G / Williams, H H / Williams, S / Willis, C / Willocq, S / Wilson, J A / Wingerter-Seez, I / Winkels, E / Winklmeier, F / Winston, O J / Winter, B T / Wittgen, M / Wobisch, M / Wolf, T M H / Wolff, R / Wolter, M W / Wolters, H / Wong, V W S / Worm, S D / Wosiek, B K / Wotschack, J / Wozniak, K W / Wu, M / Wu, S L / Wu, X / Wu, Y / Wyatt, T R / Wynne, B M / Xella, S / Xi, Z / Xia, L / Xu, D / Xu, L / Yabsley, B / Yacoob, S / Yamaguchi, D / Yamaguchi, Y / Yamamoto, A / Yamamoto, S / Yamanaka, T / Yamauchi, K / Yamazaki, Y / Yan, Z / Yang, H / Yang, Y / Yang, Z / Yao, W-M / Yap, Y C / Yasu, Y / Yatsenko, E / Wong, K H Yau / Ye, J / Ye, S / Yeletskikh, I / Yigitbasi, E / Yildirim, E / Yorita, K / Yoshihara, K / Young, C / Young, C J S / Yu, D R / Yu, J / Yuen, S P Y / Yusuff, I / Zabinski, B / Zacharis, G / Zaidan, R / Zaitsev, A M / Zakharchuk, N / Zalieckas, J / Zaman, A / Zambito, S / Zanzi, D / Zeitnitz, C / Zemla, A / Zeng, J C / Zeng, Q / Zenin, O / Ženiš, T / Zerwas, D / Zhang, D / Zhang, F / Zhang, G / Zhang, H / Zhang, J / Zhang, L / Zhang, M / Zhang, P / Zhang, R / Zhang, X / Zhang, Y / Zhang, Z / Zhao, X / Zhao, Y / Zhao, Z / Zhemchugov, A / Zhou, B / Zhou, C / Zhou, L / Zhou, M / Zhou, N / Zhu, C G / Zhu, H / Zhu, J / Zhu, Y / Zhuang, X / Zhukov, K / Zibell, A / Zieminska, D / Zimine, N I / Zimmermann, C / Zimmermann, S / Zinonos, Z / Zinser, M / Ziolkowski, M / Živković, L / Zobernig, G / Zoccoli, A / Zou, R / Nedden, M Zur / Zwalinski, L

    The European physical journal. C, Particles and fields

    2017  Volume 77, Issue 6, Page(s) 428

    Abstract: Multi-particle cumulants and corresponding Fourier harmonics are measured for azimuthal angle distributions of charged particles in [Formula: see text] collisions at [Formula: see text] = 5.02 and 13 TeV and in [Formula: see text] + Pb collisions at [ ... ...

    Abstract Multi-particle cumulants and corresponding Fourier harmonics are measured for azimuthal angle distributions of charged particles in [Formula: see text] collisions at [Formula: see text] = 5.02 and 13 TeV and in [Formula: see text] + Pb collisions at [Formula: see text] = 5.02 TeV, and compared to the results obtained for low-multiplicity [Formula: see text] collisions at [Formula: see text] = 2.76 TeV. These measurements aim to assess the collective nature of particle production. The measurements of multi-particle cumulants confirm the evidence for collective phenomena in [Formula: see text] + Pb and low-multiplicity [Formula: see text] collisions. On the other hand, the [Formula: see text] results for four-particle cumulants do not demonstrate collective behaviour, indicating that they may be biased by contributions from non-flow correlations. A comparison of multi-particle cumulants and derived Fourier harmonics across different collision systems is presented as a function of the charged-particle multiplicity. For a given multiplicity, the measured Fourier harmonics are largest in [Formula: see text], smaller in [Formula: see text] + Pb and smallest in [Formula: see text] collisions. The [Formula: see text] results show no dependence on the collision energy, nor on the multiplicity.
    Language English
    Publishing date 2017-06-26
    Publishing country France
    Document type Journal Article
    ZDB-ID 1459069-4
    ISSN 1434-6052 ; 1434-6044
    ISSN (online) 1434-6052
    ISSN 1434-6044
    DOI 10.1140/epjc/s10052-017-4988-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin.

    Zhou, Yijun / Li, Xiao-Ping / Kahn, Jennifer N / McLaughlin, John E / Tumer, Nilgun E

    Bioscience reports

    2019  Volume 39, Issue 10

    Abstract: Ricin interacts with the ribosomal P stalk to cleave a conserved adenine from the α-sarcin/ricin ... to the P stalk through electrostatic interactions to facilitate depurination. Structural analysis showed ... with Arg235. The importance of hydrophobic residues relative to Arg235 in the interaction with the P stalk ...

    Abstract Ricin interacts with the ribosomal P stalk to cleave a conserved adenine from the α-sarcin/ricin loop (SRL) of the rRNA. Ricin toxin A chain (RTA) uses Arg235 as the most critical arginine for binding to the P stalk through electrostatic interactions to facilitate depurination. Structural analysis showed that a P2 peptide binds to a hydrophobic pocket on RTA and the last two residues form hydrogen bonds with Arg235. The importance of hydrophobic residues relative to Arg235 in the interaction with the P stalk in vivo and on the toxicity of RTA is not known. Here, we mutated residues in the hydrophobic pocket to analyze their contribution to toxicity and depurination activity in yeast and in mammalian cells. We found that Leu232, Tyr183 and Phe240 contribute cumulatively to toxicity, with Leu232 being the most significant. A quadruple mutant, Y183A/L232A/R235A/F240A, which combined mutations in critical hydrophobic residues with R235A completely abolished the activity of RTA, indicating that Arg235 and hydrophobic residues are required for full biological activity. Y183A and F240A mutants had reduced activity on RNA, but higher activity on ribosomes compared with R235A in vitro, suggesting that they could partially regain activity upon interaction with ribosomes. These results expand the region of interaction between RTA and the P stalk critical for cellular activity to include the hydrophobic pocket and provide the first evidence that interaction of P stalk with the hydrophobic pocket promotes a conformational rearrangement of RTA to correctly position the active site residues for catalytic attack on the SRL.
    MeSH term(s) Binding Sites ; Hydrophobic and Hydrophilic Interactions ; Leucine ; Ribosomes/chemistry ; Ribosomes/genetics ; Ribosomes/metabolism ; Ricin/chemistry ; Ricin/genetics ; Ricin/metabolism ; Saccharomyces cerevisiae/chemistry ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
    Chemical Substances Ricin (9009-86-3) ; Leucine (GMW67QNF9C)
    Language English
    Publishing date 2019-09-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 764946-0
    ISSN 1573-4935 ; 0144-8463
    ISSN (online) 1573-4935
    ISSN 0144-8463
    DOI 10.1042/BSR20192022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cost-Effectiveness Of Ldl-P-Guided Statin Therapy.

    Folse, H J / Rengarajan, B / Goswami, D / Budoff, M / Kahn, R

    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

    2014  Volume 17, Issue 7, Page(s) A491

    Language English
    Publishing date 2014-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1471745-1
    ISSN 1524-4733 ; 1098-3015
    ISSN (online) 1524-4733
    ISSN 1098-3015
    DOI 10.1016/j.jval.2014.08.1451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5904: Show issues Location:
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  9. Article ; Online: Peptide Mimics of the Ribosomal P Stalk Inhibit the Activity of Ricin A Chain by Preventing Ribosome Binding.

    Li, Xiao-Ping / Kahn, Jennifer N / Tumer, Nilgun E

    Toxins

    2018  Volume 10, Issue 9

    Abstract: ... of the ribosomal P stalk. The ribosome interaction site and the active site are located on opposite faces of RTA ... The interaction with P proteins allows RTA to depurinate the SRL on the ribosome at physiological pH ... activity. To test this model, we synthesized peptides mimicking the last 3 to 11 amino acids of P proteins ...

    Abstract Ricin A chain (RTA) depurinates the sarcin/ricin loop (SRL) by interacting with the C-termini of the ribosomal P stalk. The ribosome interaction site and the active site are located on opposite faces of RTA. The interaction with P proteins allows RTA to depurinate the SRL on the ribosome at physiological pH with an extremely high activity by orienting the active site towards the SRL. Therefore, if an inhibitor disrupts RTA⁻ribosome interaction by binding to the ribosome binding site of RTA, it should inhibit the depurination activity. To test this model, we synthesized peptides mimicking the last 3 to 11 amino acids of P proteins and examined their interaction with wild-type RTA and ribosome binding mutants by Biacore. We measured the inhibitory activity of these peptides on RTA-mediated depurination of yeast and rat liver ribosomes. We found that the peptides interacted with the ribosome binding site of RTA and inhibited depurination activity by disrupting RTA⁻ribosome interactions. The shortest peptide that could interact with RTA and inhibit its activity was four amino acids in length. RTA activity was inhibited by disrupting its interaction with the P stalk without targeting the active site, establishing the ribosome binding site as a new target for inhibitor discovery.
    MeSH term(s) Peptides/metabolism ; Protein Binding ; Ribosomes/metabolism ; Ricin/metabolism
    Chemical Substances Peptides ; Ricin (9009-86-3)
    Language English
    Publishing date 2018-09-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins10090371
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  10. Article ; Online: Solution-Processed p-Dopant as Interlayer in Polymer Solar Cells.

    Guillain, F / Endres, J / Bourgeois, L / Kahn, A / Vignau, L / Wantz, G

    ACS applied materials & interfaces

    2016  Volume 8, Issue 14, Page(s) 9262–9267

    Abstract: We report here an original approach to dope the semiconducting polymer-metal interface in an inverted bulk-heterojunction (BHJ) organic solar cell. Solution-processed 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (F4-TCNQ), is deposited on top of ... ...

    Abstract We report here an original approach to dope the semiconducting polymer-metal interface in an inverted bulk-heterojunction (BHJ) organic solar cell. Solution-processed 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (F4-TCNQ), is deposited on top of a P3HT:PC61BM layer before deposition of the top electrode. Doping of P3HT by F4-TCNQ occurs after thermally induced diffusion at 100 °C of the latter into the BHJ. Diffusion and doping are evidenced by XPS and UV-vis-NIR absorption. XPS highlights the decrease in Fluorine concentration on top of the BHJ after annealing. In the same time, a charge transfer band attributed to doping is observed in the UV-vis-NIR absorption spectrum. Inverted polymer solar cells using solution-processed F4-TCNQ exhibit power conversion efficiency of nearly 3.5% after annealing. This simple and efficient approach, together with the low annealing temperature required to allow diffusion and doping, leads to standard efficiency P3HT:PC61BM polymer solar cells, which are suitable for printing on plastic flexible substrate.
    Language English
    Publishing date 2016-04-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.6b00356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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