LIVIVO - Search results -

Search results

Result 1 - 10 of total 330

Search options

Article ; Online: Using the AS04C-adjuvanted hepatitis B vaccine in patients classified as non-responders.

Fernández Sánchez-Escalonilla, Sara / Gonzalez-Rubio, Jesus / Najera, Alberto / Cantero Escribano, Jose Miguel / Molina Cabrero, Francisco Jesús / García Guerrero, Jesús

Transactions of the Royal Society of Tropical Medicine and Hygiene

2023 Volume 118, Issue 3, Page(s) 170–177

Abstract: Background: Chronic hepatitis B (HB) remains a significant global health concern, despite the widespread availability of the HB vaccine. While the standard vaccine demonstrates an impressive serological response rate exceeding 90%, a subset of ... ...

Abstract	Background: Chronic hepatitis B (HB) remains a significant global health concern, despite the widespread availability of the HB vaccine. While the standard vaccine demonstrates an impressive serological response rate exceeding 90%, a subset of individuals exhibit suboptimal immunity. This study aims to elucidate the efficacy of the AS04C-adjuvanted HB vaccine in addressing non-responsiveness. Methods: Conducted at the Preventive Medicine Service of the University Albacete Hospital in Spain from 2017 to 2021, this single-center observational study enrolled 195 patients. Among them, 126 (65%) were classified as non-responders following one or two complete standard vaccination courses. Results: After the administration of a complete four-dose regimen of the AS04C-adjuvanted vaccine, 73.81% of non-responder patients exhibited antibody titers indicative of robust immunity (anti-HBs >10). Conclusions: These findings underscore the pivotal role of the AS04C-adjuvanted HB vaccine in addressing non-responsiveness, emphasizing its potential as a crucial tool in augmenting immunization strategies for various populations. This includes non-responders to standard vaccination, individuals with chronic kidney disease, those requiring seroprotection due to factors like immunosuppression or occupational hazards, as well as patients for whom conventional revaccination strategies have proven futile. Additional research is needed to expand on the promising results obtained through our protocol.
MeSH term(s)	Humans ; Hepatitis B Vaccines/therapeutic use ; Immunization, Secondary ; Vaccination/methods ; Hepatitis B Antibodies ; Renal Insufficiency, Chronic ; Hepatitis B/prevention & control
Chemical Substances	Hepatitis B Vaccines ; Hepatitis B Antibodies
Language	English
Publishing date	2023-10-15
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	441375-1
ISSN	1878-3503 ; 0035-9203
ISSN (online)	1878-3503
ISSN	0035-9203
DOI	10.1093/trstmh/trad078
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Un I Zs.257: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Analytical errors due to biotin interference.

Letosa-Gaudó, Jesús / González-Rubio, Francisca / Ioakeim-Skoufa, Ignatios

Medicina clinica

2020 Volume 157, Issue 2, Page(s) 95–96

MeSH term(s)	Biotin ; Diagnostic Errors ; Humans ; Hyperthyroidism ; Immunoassay
Chemical Substances	Biotin (6SO6U10H04)
Language	Spanish
Publishing date	2020-07-25
Publishing country	Spain
Document type	Letter
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2020.04.049
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.279: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Spatial analysis of COVID-19 hospitalised cases in an entire city: The risk of studying only lattice data.

Garcia-Morata, Marta / Gonzalez-Rubio, Jesus / Segura, Tomas / Najera, Alberto

The Science of the total environment

2021 Volume 806, Issue Pt 1, Page(s) 150521

Abstract: We live in a global pandemic caused by the COVID-19 disease where severe social distancing measures are necessary. Some of these measures have been taken into account by the administrative boundaries within cities (neighborhoods, postal districts, etc.). ...

Abstract	We live in a global pandemic caused by the COVID-19 disease where severe social distancing measures are necessary. Some of these measures have been taken into account by the administrative boundaries within cities (neighborhoods, postal districts, etc.). However, considering only administrative boundaries in decision making can prove imprecise, and could have consequences when it comes to taking effective measures. To solve the described problems, we present an epidemiological study that proposes using spatial point patterns to delimit spatial units of analysis based on the highest local incidence of hospitalisations instead of administrative limits during the first COVID-19 wave. For this purpose, the 579 addresses of the cases hospitalised between March 3 and April 6, 2020, in Albacete (Spain), and the addresses of the random sample of 383 controls from the Inhabitants Register of the city of Albacete, were georeferenced. The risk ratio in those hospitalised for COVID-19 was compatible with the constant risk ratio in Albacete (p = 0.49), but areas with a significantly higher risk were found and coincided with those with greater economic inequality (Gini Index). Moreover, two districts had areas with a significantly high incidence that were masked by others with a significantly low incidence. In conclusion, taking measures conditioned exclusively by administrative limits in a pandemic can cause problems caused by managing entire districts with lax measures despite having interior areas with high significant incidences. In a pandemic context, georeferencing disease cases in real time and spatially comparing them to updated random population controls to automatically and accurately detect areas with significant incidences are suggested. This would facilitate decision making, which must be fast and accurate in these situations.
MeSH term(s)	COVID-19 ; Cities ; Humans ; Pandemics ; SARS-CoV-2 ; Spatial Analysis
Language	English
Publishing date	2021-09-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.150521
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 949: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Comparison of statistic methods for censored personal exposure to RF-EMF data.

Najera, Alberto / Ramirez-Vazquez, Raquel / Arribas, Enrique / Gonzalez-Rubio, Jesus

Environmental monitoring and assessment

2020 Volume 192, Issue 2, Page(s) 77

Abstract: Several studies have characterized personal exposure to RF-EMF, which allows possible effects on health to be studied. All equipment has a detection limit, below which we obtain nondetects or censored data. This problem is a challenge for researchers as ... ...

Abstract	Several studies have characterized personal exposure to RF-EMF, which allows possible effects on health to be studied. All equipment has a detection limit, below which we obtain nondetects or censored data. This problem is a challenge for researchers as it makes the analysis of such data complex. We suggest reconsidering the statistical protocols of the nondetects analysis by comparing four different methods. Three of them substitute censored data using different approaches: regression on order of statistics (ROS) to simulate data below the detection limit (Method 1), substituting nondetect values by the detection limit divided by 2 (Method 2), a naïve calculation (Method 3) using the detection limit as a valid measurement. The fourth method consists of considering censored data to be missing values (Method 4). This article examines how these methods affect the quantification of personal exposure. We considered data from 14 frequency bands from FM to WiMax measured in Albacete (Spain) for 76 days every 10 s by a personal exposimeter (PEM) Satimo EME Spy 140.Methods 3 and 2 gave similar mean and median values to Method 1, but both underestimated the mean values when high nondetects records occurred, which conditioned the physical description of the real situation. The mean values calculated by Method 4 differed from those obtained by Method 1 but were similar when the percentage of nondetects was below 20%.Our comparison suggests that nondetects can be neglected when the percentage of censored data is low to provide a more realistic physical situation.
MeSH term(s)	Algorithms ; Electromagnetic Fields ; Environmental Exposure/analysis ; Environmental Monitoring ; Humans ; Limit of Detection ; Radio Waves ; Regression Analysis ; Research Design ; Spain
Language	English
Publishing date	2020-01-02
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-019-8021-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5186: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: Comment on "The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials

Ramirez-Vazquez, Raquel / Escobar, Isabel / Gonzalez-Rubio, Jesus / Arribas, Enrique

International journal of biomaterials

2019 Volume 2019, Page(s) 2593205

Language	English
Publishing date	2019-07-01
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2494344-7
ISSN	1687-8795 ; 1687-8787
ISSN (online)	1687-8795
ISSN	1687-8787
DOI	10.1155/2019/2593205
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Personal Exposure Assessment to Wi-Fi Radiofrequency Electromagnetic Fields in Mexican Microenvironments.

Ramirez-Vazquez, Raquel / Gonzalez-Rubio, Jesus / Escobar, Isabel / Suarez Rodriguez, Carmen Del Pilar / Arribas, Enrique

International journal of environmental research and public health

2021 Volume 18, Issue 4

Abstract: In recent years, personal exposure to Radiofrequency Electromagnetic Fields (RF-EMF) has substantially increased, and most studies about RF-EMF with volunteers have been developed in Europe. To the best of our knowledge, this is the first study carried ... ...

Abstract	In recent years, personal exposure to Radiofrequency Electromagnetic Fields (RF-EMF) has substantially increased, and most studies about RF-EMF with volunteers have been developed in Europe. To the best of our knowledge, this is the first study carried out in Mexico with personal exposimeters. The main objective was to measure personal exposure to RF-EMF from Wireless Fidelity or wireless Internet connection (Wi-Fi) frequency bands in Tamazunchale, San Luis Potosi, Mexico, to compare results with maximum levels permitted by international recommendations and to find if there are differences in the microenvironments subject to measurements. The study was conducted with 63 volunteers in different microenvironments: home, workplace, outside, schools, travel, and shopping. The mean minimum values registered were 146.5 μW/m
MeSH term(s)	Cell Phone ; Cities ; Electromagnetic Fields/adverse effects ; Environmental Exposure ; Europe ; Humans ; Mexico ; Radio Waves/adverse effects
Language	English
Publishing date	2021-02-14
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph18041857
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article ; Online: Identifying multimorbidity profiles associated with COVID-19 severity in chronic patients using network analysis in the PRECOVID Study.

Carmona-Pírez, Jonás / Gimeno-Miguel, Antonio / Bliek-Bueno, Kevin / Poblador-Plou, Beatriz / Díez-Manglano, Jesús / Ioakeim-Skoufa, Ignatios / González-Rubio, Francisca / Poncel-Falcó, Antonio / Prados-Torres, Alexandra / Gimeno-Feliu, Luis A

Scientific reports

2022 Volume 12, Issue 1, Page(s) 2831

Abstract: A major risk factor of COVID-19 severity is the patient's health status at the time of the infection. Numerous studies focused on specific chronic diseases and identified conditions, mainly cardiovascular ones, associated with poor prognosis. However, ... ...

Abstract	A major risk factor of COVID-19 severity is the patient's health status at the time of the infection. Numerous studies focused on specific chronic diseases and identified conditions, mainly cardiovascular ones, associated with poor prognosis. However, chronic diseases tend to cluster into patterns, each with its particular repercussions on the clinical outcome of infected patients. Network analysis in our population revealed that not all cardiovascular patterns have the same risk of COVID-19 hospitalization or mortality and that this risk depends on the pattern of multimorbidity, besides age and sex. We evidenced that negative outcomes were strongly related to patterns in which diabetes and obesity stood out in older women and men, respectively. In younger adults, anxiety was another disease that increased the risk of severity, most notably when combined with menstrual disorders in women or atopic dermatitis in men. These results have relevant implications for organizational, preventive, and clinical actions to help meet the needs of COVID-19 patients.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Multimorbidity ; Retrospective Studies ; Spain/epidemiology ; Young Adult
Language	English
Publishing date	2022-02-18
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-06838-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Characterisation of personal exposure to environmental radiofrequency electromagnetic fields in Albacete (Spain) and assessment of risk perception.

Ramirez-Vazquez, Raquel / Gonzalez-Rubio, Jesus / Arribas, Enrique / Najera, Alberto

Environmental research

2019 Volume 172, Page(s) 109–116

Abstract: In the last decades, exposure to radiofrequency electromagnetic fields (RF-EMF) has substantially increased as new wireless technologies have been introduced. Society has become more concerned about the possible effects of RF-EMF on human health in ... ...

Abstract	In the last decades, exposure to radiofrequency electromagnetic fields (RF-EMF) has substantially increased as new wireless technologies have been introduced. Society has become more concerned about the possible effects of RF-EMF on human health in parallel to the increase in their exposure. The appearance of personal exposimeters opens up wide-ranging research possibilities. Despite studies having characterised personal exposure to RF-EMF, part of the population is still worried, to the extent that psychogenic diseases ("nocebo" effect) appear, and patients suffer. It could be interesting to share personal exposure results with the population to better understand and promote public health. The main objective was to characterise personal exposure to environmental RF-EMF in Albacete (166,000 inhabitants, SE Spain), and assess the effect of sharing the results of the study on participants' risk perception. Measurements were taken by a personal Satimo EME SPY 140 exposimeter, which was programmed every 10 s for 24 h. To measure personal exposure to RF-EMF, we worked with 75 volunteers. Their personal exposure, 14 microenvironments in the city, e.g., home, outdoors, work, etc., and possible time differences were analysed. After participating in the study, 35 participants completed a questionnaire about their RF-EMF risk perception, which was also answered by a control sample to compare the results (N = 36). The total average exposure of 14 bands was 37.7 μW/m
MeSH term(s)	Cell Phone ; Electromagnetic Fields ; Environmental Exposure ; Humans ; Perception ; Radiation Exposure/analysis ; Radio Waves ; Risk-Taking ; Spain ; Surveys and Questionnaires
Language	English
Publishing date	2019-02-12
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2019.02.015
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Spatial analysis of COVID-19 hospitalised cases in an entire city: The risk of studying only lattice data

Garcia-Morata, Marta / Gonzalez-Rubio, Jesus / Segura, Tomas / Najera, Alberto

Science of the total environment. 2022 Feb. 01, v. 806

2022

Abstract	We live in a global pandemic caused by the COVID-19 disease where severe social distancing measures are necessary. Some of these measures have been taken into account by the administrative boundaries within cities (neighborhoods, postal districts, etc.). However, considering only administrative boundaries in decision making can prove imprecise, and could have consequences when it comes to taking effective measures. To solve the described problems, we present an epidemiological study that proposes using spatial point patterns to delimit spatial units of analysis based on the highest local incidence of hospitalisations instead of administrative limits during the first COVID-19 wave.For this purpose, the 579 addresses of the cases hospitalised between March 3 and April 6, 2020, in Albacete (Spain), and the addresses of the random sample of 383 controls from the Inhabitants Register of the city of Albacete, were georeferenced.The risk ratio in those hospitalised for COVID-19 was compatible with the constant risk ratio in Albacete (p = 0.49), but areas with a significantly higher risk were found and coincided with those with greater economic inequality (Gini Index). Moreover, two districts had areas with a significantly high incidence that were masked by others with a significantly low incidence.In conclusion, taking measures conditioned exclusively by administrative limits in a pandemic can cause problems caused by managing entire districts with lax measures despite having interior areas with high significant incidences. In a pandemic context, georeferencing disease cases in real time and spatially comparing them to updated random population controls to automatically and accurately detect areas with significant incidences are suggested. This would facilitate decision making, which must be fast and accurate in these situations.
Keywords	COVID-19 infection ; environment ; epidemiological studies ; georeferencing ; pandemic ; relative risk ; social inequality ; Spain
Language	English
Dates of publication	2022-0201
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.150521
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 74/341: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Personal RF-EMF exposure from mobile phone base stations during temporary events.

Ramirez-Vazquez, Raquel / Gonzalez-Rubio, Jesus / Arribas, Enrique / Najera, Alberto

Environmental research

2019 Volume 175, Page(s) 266–273

Abstract: Background: In recent years, radiofrequency electromagnetic fields (RF-EMF) exposure has increased owing to new communication technologies. Simultaneously, increased exposure to RF-EMF has led to society's growing concern about the possible effects they ...

Abstract	Background: In recent years, radiofrequency electromagnetic fields (RF-EMF) exposure has increased owing to new communication technologies. Simultaneously, increased exposure to RF-EMF has led to society's growing concern about the possible effects they may have on human health. Many studies have described personal RF-EMF exposure by using personal exposimeters to know a population's daily exposure to mobile phone base stations and to other sources whose installations tend to be permanent. Nonetheless during special events like concerts or fairs, where many people gather, permanent installations might not suffice to cover demand. So telephone companies install temporary stations for these events, and modify the exposure pattern of these areas or populations. Objective: To study if installing temporary antennae for large events, and high concentrations of mobile phones, modify the exposure pattern compared to usual situations. Methods: Personal RF-EMF exposure from mobile phones (uplink) and mobile phone base stations (downlink) installed at the 2017 Albacete Fair (Spain) was recorded. Between 7 and 17 September, more than 2,500,000 people visited this Fair. Measurements were taken by two Satimo EME SPY 140 personal exposimeters, placed one each side of a research team member's waist. These exposimeters were programmed to take measurements every 4 s at different time of day; morning, afternoon and night; and in several places, around the Fair Enclosure (zones Ejidos and Paseo) and inside the enclosure (Interior). These measurements were repeated on a weekday, at the weekend and the day after the Fair ended after temporary base stations had been removed. They were also taken for 1 h in all three zones, for each time of day; that is, 9 h were recorded for each study day. Results: The mean RF-EMF recorded exposure from base stations (downlink-DL) on the days the Fair opened (morning, afternoon and night) for the three studied zones was 791.8 μW/m Conclusions: Installing mobile phone base stations, and a dense public using mobile phones, imply a significant increase in personal RF-EMF exposure compared to that recorded during normal periods in the same area. However, the recorded measurements were below legally established limits.
MeSH term(s)	Cell Phone ; Communication ; Electromagnetic Fields ; Environmental Exposure ; Humans ; Radio Waves ; Spain
Language	English
Publishing date	2019-05-21
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2019.05.033
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito