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Article ; Online: Devoting attention to the management of community-acquired pneumonia for the elderly.

Song, Peipei

2020 Volume 14, Issue 3, Page(s) 151–152

Abstract: Community-acquired pneumonia (CAP) is the third leading contributor to lost disability-adjusted life years worldwide, and this is especially true in the elderly population. In order to reduce the burden of disease, effective management of CAP is crucial ... ...

Abstract	Community-acquired pneumonia (CAP) is the third leading contributor to lost disability-adjusted life years worldwide, and this is especially true in the elderly population. In order to reduce the burden of disease, effective management of CAP is crucial to public health in terms of maintaining and promoting the health of the elderly and involves safe drug use, vaccinations, early treatment in the ICU, and health education. Since the long-term mortality of CAP is particularly high in the elderly, biomarkers and a predictive diagnostic model of CAP should be developed in future research.
MeSH term(s)	Aged ; Aged, 80 and over ; Anti-Bacterial Agents/administration & dosage ; Attention ; Community-Acquired Infections/drug therapy ; Community-Acquired Infections/epidemiology ; Community-Acquired Infections/prevention & control ; Disease Management ; Humans ; Patient Education as Topic/methods ; Pneumococcal Vaccines/administration & dosage ; Pneumonia/drug therapy ; Pneumonia/epidemiology ; Pneumonia/prevention & control
Chemical Substances	Anti-Bacterial Agents ; Pneumococcal Vaccines
Language	English
Publishing date	2020-07-23
Publishing country	Japan
Document type	Letter
ZDB-ID	2568828-5
ISSN	1881-784X ; 1881-7831
ISSN (online)	1881-784X
ISSN	1881-7831
DOI	10.5582/ddt.2020.03055
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Dual fluorescence properties and enhanced thermal stability of SrSi

Wang, Jinlong / Song, Hao / Dong, Peipei / Zhao, Zihan / Zhang, Yanjie

RSC advances

2023 Volume 13, Issue 10, Page(s) 6442–6452

Abstract: Nowadays, considerable efforts have been extensively devoted to explore a general strategy for improving the color uniformity and thermal stability of phosphors, which is vital for its applications in health and comfort lighting. In this study, the ... ...

Abstract	Nowadays, considerable efforts have been extensively devoted to explore a general strategy for improving the color uniformity and thermal stability of phosphors, which is vital for its applications in health and comfort lighting. In this study, the SrSi
Language	English
Publishing date	2023-02-23
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d2ra07562h
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Article ; Online: Performance of disk diffusion method for aztreonam in combination with avibactam against Enterobacteriales.

Yin, Dandan / Song, Peipei / Jiang, Lan / Xu, Jian / Hu, Fupin

The Journal of antimicrobial chemotherapy

2024

Abstract: Objectives: To evaluate the performance of an in-house developed disk diffusion method for aztreonam in combination with avibactam against Enterobacteriales.: Methods: The in vitro antibacterial activity of aztreonam with avibactam against 204 ... ...

Abstract	Objectives: To evaluate the performance of an in-house developed disk diffusion method for aztreonam in combination with avibactam against Enterobacteriales. Methods: The in vitro antibacterial activity of aztreonam with avibactam against 204 carbapenemase-producing Enterobacteriales was determined by a disk diffusion method, with a broth microdilution method as a reference. Results: The optimal S/R breakpoints for disk diffusion tests of 30/20 and 10/4 µg disks, calculated by the dBETs software using the model-based approaches, were ≥22/≤21 and ≥12/≤11 mm, respectively. On the basis of the estimated breakpoints, the CAs for disk diffusion tests of 30/20 and 10/4 µg aztreonam/avibactam disks were both 98.0%, with 0.5% major error and 37.5% very major error. Conclusions: The home-made disk diffusion method is an economical and practical method for clinical microbiology laboratories to determine the antibacterial susceptibility of aztreonam with avibactam against Enterobacteriales.
Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Journal Article
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkae097
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Zs.A 1197: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Combined effects of toxic Karenia mikimotoi and hypoxia on the juvenile abalone Haliotis discus hannai

Yue Zhang / Xiuxian Song / Peipei Zhang

Frontiers in Marine Science, Vol

2023 Volume 10

Abstract: Eutrophication in aquaculture areas concurrently leads to a high incidence of dissolved oxygen deficiency and toxic algal blooms. The combined effects of hypoxia and typical toxic algae on cultured organisms should be given sufficient consideration. ... ...

Abstract	Eutrophication in aquaculture areas concurrently leads to a high incidence of dissolved oxygen deficiency and toxic algal blooms. The combined effects of hypoxia and typical toxic algae on cultured organisms should be given sufficient consideration. Abalone breeding in China has greatly suffered from hypoxia and toxic Karenia mikimotoi blooms for many years. In this study, the individual and combined effects of the toxic dinoflagellate, K. mikimotoi, and hypoxia on juvenile abalone were determined based on abalone survival and oxidative stress indicators in their gills, hepatopancreas and hemolymph. The results showed that at a density of 106 to 3×107 cells/L, K. mikimotoi alone had a negligible influence on the survival of juvenile abalone under sufficient dissolved oxygen (DO) conditions. The 24 h-half lethal concentration (LC50) of DO alone for juvenile abalone was 0.75 mg/L in seawater. When K. mikimotoi was added at a density of 3×106 cells/L, the 24 h-LC50 of DO for juvenile abalone significantly increased to 2.59 mg/L, indicating obvious synergistic effects. The individual effects of hypoxia or K. mikimotoi on the oxidative stress indicators were limited, and only the superoxide dismutase (SOD) activity in the abalone gills significantly decreased under K. mikimotoi stress. However, the combined stress of hypoxia and K. mikimotoi led to significant changes in the antioxidant indicators in all tested tissues. The SOD activity in gills and hepatopancreas decreased, while the SOD and catalase (CAT) activity and malondialdehyde (MDA) content in the hemolymph increased due to the combined stress of hypoxia and K. mikimotoi. These results illustrated that the synergistic effects of hypoxia and K. mikimotoi caused serious oxidative damage in abalone and that the hemolymph exhibited greater sensitivity than did the gills and hepatopancreas. Further investigation found that K. mikimotoi increased the oxygen consumption rate in abalone and that hypoxia enhanced the hemolytic toxicity of K. mikimotoi. These results ...
Keywords	hypoxia ; Karenia mikimotoi ; Haliotis discus hannai ; oxidative stress ; synergistic effects ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
Subject code	610
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Analysis of acceptance and influencing factors by real-time three-dimensional pelvic floor ultrasonography

Qian Peipei / Song Qianqian / Qian Zhaogao / Huang Zeping

Xin yixue, Vol 54, Iss 9, Pp 650-

2023 Volume 654

Abstract: Objective To investigate the acceptance， participation rate， and awareness rate of real-time three-dimensional pelvic floor ultrasonography among the female population， and to analyze the influence factors. Methods A total of 855 women were face-to-face ... ...

Abstract	Objective To investigate the acceptance， participation rate， and awareness rate of real-time three-dimensional pelvic floor ultrasonography among the female population， and to analyze the influence factors. Methods A total of 855 women were face-to-face surveyed by using the general data questionnaire. The acceptance， participation rate， and awareness rate of real-time three-dimensional pelvic floor ultrasonography were analyzed. According to the survey results， all participants were divided into those who accepted pelvic floor ultrasonography group （acceptance group） and those who rejected pelvic floor ultrasonography group （rejection group）. The differences in education level， type of medical insurance， annual household income per capita， clinical symptoms， history of disease and awareness of pelvic floor ultrasonography were compared between two groups. The influencing factors of low acceptance of pelvic floor ultrasonography in female population were analyzed. Results A total of 808 valid questionnaires were returned. Among all valid respondents （n=808）， 86.6% （n=700） were willing to receive real-time three-dimensional pelvic floor ultrasonography. 95 participants （11.8%） had received pelvic floor ultrasonography before. The majority of respondents （92.6%） had little or no knowledge of pelvic floor ultrasonography. “Paying attention to their health and finding problems as early as possible” was the main reason for being willing to accept pelvic floor ultrasound examination， while the main reason for rejection was“do not understand the work of the project”. Significant differences were observed in the educational level， type of medical insurance， annual household income per capita， clinical symptoms， and awareness rate between two groups （all P < 0.05）. Multivariate Logistic analysis showed that the population without urinary leakage symptoms （OR=0.162， 95%CI：0.064-0.408， P < 0.001） and the population with low annual household income per capita （OR=0.495， 95%CI： 0.319-0.766， P = 0.002） were less willing ...
Keywords	pelvic floor ultrasonography\|female pelvic floor dysfunction\|acceptance\|participation rate\|influencing factor ; Medicine ; R
Subject code	630
Language	Chinese
Publishing date	2023-09-01T00:00:00Z
Publisher	Editorial Office of Journal of New Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Emotional Video Captioning With Vision-Based Emotion Interpretation Network.

Song, Peipei / Guo, Dan / Yang, Xun / Tang, Shengeng / Wang, Meng

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

2024 Volume 33, Page(s) 1122–1135

Abstract: Effectively summarizing and re-expressing video content by natural languages in a more human-like fashion is one of the key topics in the field of multimedia content understanding. Despite good progress made in recent years, existing efforts usually ... ...

Abstract	Effectively summarizing and re-expressing video content by natural languages in a more human-like fashion is one of the key topics in the field of multimedia content understanding. Despite good progress made in recent years, existing efforts usually overlooked the emotions in user-generated videos, thus making the generated sentence a bit boring and soulless. To fill the research gap, this paper presents a novel emotional video captioning framework in which we design a Vision-based Emotion Interpretation Network to effectively capture the emotions conveyed in videos and describe the visual content in both factual and emotional languages. Specifically, we first model the emotion distribution over an open psychological vocabulary to predict the emotional state of videos. Then, guided by the discovered emotional state, we incorporate visual context, textual context, and visual-textual relevance into an aggregated multimodal contextual vector to enhance video captioning. Furthermore, we optimize the network in a new emotion-fact coordinated way that involves two losses- Emotional Indication Loss and Factual Contrastive Loss, which penalize the error of emotion prediction and visual-textual factual relevance, respectively. In other words, we innovatively introduce emotional representation learning into an end-to-end video captioning network. Extensive experiments on public benchmark datasets, EmVidCap and EmVidCap-S, demonstrate that our method can significantly outperform the state-of-the-art methods by a large margin. Quantitative ablation studies and qualitative analyses clearly show that our method is able to effectively capture the emotions in videos and thus generate emotional language sentences to interpret the video content.
MeSH term(s)	Humans ; Benchmarking ; Cognition ; Emotions
Language	English
Publishing date	2024-02-06
Publishing country	United States
Document type	Journal Article
ISSN	1941-0042
ISSN (online)	1941-0042
DOI	10.1109/TIP.2024.3359045
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Article ; Online: Neoadjuvant therapies in resectable hepatocellular carcinoma: Exploring strategies to improve prognosis.

Ma, Ya-Nan / Jiang, Xuemei / Song, Peipei / Tang, Wei

Bioscience trends

2024 Volume 18, Issue 1, Page(s) 21–41

Abstract: Hepatocellular carcinoma (HCC), a challenging malignancy, often necessitates surgical intervention, notably liver resection. However, the high recurrence rate, reaching 70% within 5 years post-resection, significantly impacts patient outcomes. ... ...

Abstract	Hepatocellular carcinoma (HCC), a challenging malignancy, often necessitates surgical intervention, notably liver resection. However, the high recurrence rate, reaching 70% within 5 years post-resection, significantly impacts patient outcomes. Neoadjuvant therapies aim to preoperatively address this challenge, reducing lesion size, improving surgical resection rates, deactivating potential micro-metastases, and ultimately lowering postoperative recurrence rates. This review concentrates on advances in research on and clinical use of neoadjuvant therapies for HCC, with particular attention to the use of immune checkpoint inhibitors (ICIs) targeting programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-L1), and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4). Ongoing clinical studies exploring immunotherapy combined with a tyrosine kinase inhibitor (TKI), interventional therapy, radiotherapy, and other modalities offer promising insights into overcoming resistance to monotherapies. In summary, neoadjuvant therapies hold significant promise in terms of improving the prognosis for patients with HCC and enhancing long-term survival, particularly through innovative combination strategies.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/surgery ; Liver Neoplasms/drug therapy ; Liver Neoplasms/surgery ; Neoadjuvant Therapy ; Immunotherapy
Language	English
Publishing date	2024-02-20
Publishing country	Japan
Document type	Review ; Journal Article
ZDB-ID	2543899-2
ISSN	1881-7823 ; 1881-7823
ISSN (online)	1881-7823
ISSN	1881-7823
DOI	10.5582/bst.2023.01436
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diagnostic value of bedside lung ultrasound and 12-zone score in the 65 cases of neonatal respiratory distress syndrome and its severity.

Huang, Peipei / Chen, Deng / Liu, Xiuxiang / Zhang, Xiang / Song, Xiazi

Biomedical engineering online

2024 Volume 23, Issue 1, Page(s) 29

Abstract: Objective: To explore the predictive value of bedside lung ultrasound score in the severity of neonatal respiratory distress syndrome (NRDS) and mechanical ventilation and extubation.: Methods: The clinical data of 65 neonates with NRDS and invasive ... ...

Abstract	Objective: To explore the predictive value of bedside lung ultrasound score in the severity of neonatal respiratory distress syndrome (NRDS) and mechanical ventilation and extubation. Methods: The clinical data of 65 neonates with NRDS and invasive mechanical ventilation diagnosed in the neonatal intensive care unit of our hospital from July 2021 to July 2022 were retrospectively analyzed. 65 neonates were included in the NRDS group, and 40 neonates with other common lung diseases were selected as the other lung disease groups. All neonates underwent lung ultrasound and X-ray examination. The correlation between lung ultrasound scores and arterial blood gas indexes was analyzed by Pearson. The efficacy of successful evacuation of mechanical ventilation was evaluated by lung ultrasound analysis by ROC curve analysis. Results: The positive rates of lung consolidation and white lung in NRDS group were higher than the other lung disease groups (P < 0.05). The positive rates of bronchial inflation sign and double lung points were lower than these in the other lung disease groups (P < 0.05). The ultrasound scores of both lungs, left lung, right lung, bilateral lung and double basal lung in the NRDS group were significantly higher than those in the other lung disease groups (P < 0.05). There was a significant positive correlation between lung ultrasound score and X-ray grade (r = 0.841, P < 0.001). The area under the curve (AUC) of lung ultrasound score for the differential diagnosis of NRDS and common lung diseases was 0.907. The AUC of lung ultrasound score in the differential diagnosis of mild and moderate, and moderate and severe NRDS were 0.914 and 0.933, respectively, which had high clinical value. The lung ultrasound score was positively correlated with the level of PaCO Conclusion: The bedside lung ultrasound score can intuitively reflect the respiratory status of neonates, which provides clinicians with an important basis for disease evaluation.
MeSH term(s)	Infant, Newborn ; Humans ; Retrospective Studies ; Respiratory Distress Syndrome, Newborn/diagnostic imaging ; Thorax ; Bronchi ; Ultrasonography
Language	English
Publishing date	2024-03-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2084374-4
ISSN	1475-925X ; 1475-925X
ISSN (online)	1475-925X
ISSN	1475-925X
DOI	10.1186/s12938-024-01224-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Large-Scale Expansion of Porcine Adipose-Derived Stem Cells Based on Microcarriers System for Cultured Meat Production.

Song, Wenjuan / Liu, Peipei / Li, Huixia / Ding, Shijie

Foods (Basel, Switzerland)

2022 Volume 11, Issue 21

Abstract: Cultured meat is an innovative meat-production technology that does not rely on animal husbandry. As a new food component, cultured fat is of great significance to cultured meat. In this study, we isolated adipose-derived stem cells (ADSCs) and ... ...

Abstract	Cultured meat is an innovative meat-production technology that does not rely on animal husbandry. As a new food component, cultured fat is of great significance to cultured meat. In this study, we isolated adipose-derived stem cells (ADSCs) and identified the purity by immunofluorescence staining of ADSC-specific surface marker proteins CD44 and CD29 and showed that most of the cells were positive for CD29 and CD44. In addition, we detected the expression of
Language	English
Publishing date	2022-10-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods11213364
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Article: Recent deep learning models for dementia as point-of-care testing: Potential for early detection.

Karako, Kenji / Song, Peipei / Chen, Yu

Intractable & rare diseases research

2023 Volume 12, Issue 1, Page(s) 1–4

Abstract: Deep learning has been intensively researched over the last decade, yielding several new models for natural language processing, images, speech and time series processing that have dramatically improved performance. This wave of technological ... ...

Abstract	Deep learning has been intensively researched over the last decade, yielding several new models for natural language processing, images, speech and time series processing that have dramatically improved performance. This wave of technological developments in deep learning is also spreading to medicine. The effective use of deep learning in medicine is concentrated in diagnostic imaging-related applications, but deep learning has the potential to lead to early detection and prevention of diseases. Physical aspects of disease that went unnoticed can now be used in diagnosis with deep learning. In particular, deep learning models for the early detection of dementia have been proposed to predict cognitive function based on various information such as blood test results, speech, and the appearance of the face, where the effects of dementia can be seen. Deep learning is a useful diagnostic tool, as it has the potential to detect diseases early based on trivial aspects before clear signs of disease appear. The ability to easily make a simple diagnosis based on information such as blood test results, voice, pictures of the body, and lifestyle is a method suited to point-of-cate testing, which requires immediate testing at the desired time and place. Over the past few years, the process of predicting disease can now be visualized using deep learning, providing insights into new methods of diagnosis.
Language	English
Publishing date	2023-02-17
Publishing country	Japan
Document type	Editorial
ZDB-ID	2672570-8
ISSN	2186-361X ; 2186-3644
ISSN (online)	2186-361X
ISSN	2186-3644
DOI	10.5582/irdr.2023.01015
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