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  1. Book ; Online: Chapter Biofilm Formation in Uropathogenic Escherichia coli Strains: Relationship with Urovirulence Factors and Antimicrobial Resistance

    Soto, Sara M. / Marco, Francesc / Guiral, Elisabet / Vila, Jordi

    2011  

    Keywords Radiology ; Medicine
    Size 1 Online-Ressource
    Publisher InTechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021047563
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Cutaneous ulcer with thrombogenic vasculopathy in a patient receiving bevacizumab.

    Vila-Payeras, Aina / Iglesias-González, María / Terrasa-Sagristá, Fernando / Parera-Amer, Elisabet

    Indian journal of dermatology, venereology and leprology

    2021  Volume 87, Issue 2, Page(s) 268–270

    MeSH term(s) Aged ; Angiogenesis Inhibitors/adverse effects ; Bevacizumab/adverse effects ; Female ; Humans ; Leg Ulcer/chemically induced ; Leg Ulcer/diagnosis ; Thrombotic Microangiopathies/chemically induced ; Thrombotic Microangiopathies/diagnosis
    Chemical Substances Angiogenesis Inhibitors ; Bevacizumab (2S9ZZM9Q9V)
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_398_20
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    Zs.A 85: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged Extracorporeal Membrane Oxygenation Support.

    Martínez-Martínez, María / Schmidt, Matthieu / Broman, Lars Mikael / Roncon-Albuquerque, Roberto / Langouet, Elise / Campos, Isabel / Argudo, Eduard / Domènech Vila, Josep Maria / Sastre, Sara Martín / Gallart, Elisabet / Ferrer, Ricard / Combes, Alain / Riera, Jordi

    Annals of the American Thoracic Society

    2024  Volume 21, Issue 3, Page(s) 449–455

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation ; Retrospective Studies ; Treatment Outcome ; Functional Status ; COVID-19/therapy ; Respiratory Distress Syndrome ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202306-572OC
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    Zs.A 5828: Show issues Location:
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  4. Article ; Online: Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease.

    Riberas-Sánchez, Andrea / Puig-Parnau, Irene / Vila-Solés, Laia / Garcia-Brito, Soleil / Aldavert-Vera, Laura / Segura-Torres, Pilar / Huguet, Gemma / Kádár, Elisabet

    Journal of psychiatry & neuroscience : JPN

    2024  Volume 49, Issue 2, Page(s) E96–E108

    Abstract: Background: The assessment of deep brain stimulation (DBS) as a therapeutic alternative for treating Alzheimer disease (AD) is ongoing. We aimed to determine the effects of intracranial self-stimulation at the medial forebrain bundle (MFB-ICSS) on ... ...

    Abstract Background: The assessment of deep brain stimulation (DBS) as a therapeutic alternative for treating Alzheimer disease (AD) is ongoing. We aimed to determine the effects of intracranial self-stimulation at the medial forebrain bundle (MFB-ICSS) on spatial memory, neurodegeneration, and serum expression of microRNAs (miRNAs) in a rat model of sporadic AD created by injection of streptozotocin. We hypothesized that MFB-ICSS would reverse the behavioural effects of streptozotocin and modulate hippocampal neuronal density and serum levels of the miRNAs.
    Methods: We performed Morris water maze and light-dark transition tests. Levels of various proteins, specifically amyloid-β precurser protein (APP), phosphorylated tau protein (pTAU), and sirtuin 1 (SIRT1), and neurodegeneration were analyzed by Western blot and Nissl staining, respectively. Serum miRNA expression was measured by reverse transcription polymerase chain reaction.
    Results: Male rats that received streptozotocin had increased hippocampal levels of pTAU S202/T205, APP, and SIRT1 proteins; increased neurodegeneration in the CA1, dentate gyrus (DG), and dorsal tenia tecta; and worse performance in the Morris water maze task. No differences were observed in miRNAs, except for miR-181c and miR-let-7b. After MFB-ICSS, neuronal density in the CA1 and DG regions and levels of miR-181c in streptozotocin-treated and control rats were similar. Rats that received streptozotocin and underwent MFB-ICSS also showed lower levels of miR-let-7b and better spatial learning than rats that received streptozotocin without MFB-ICSS.
    Limitations: The reversal by MFB-ICSS of deficits induced by streptozotocin was fairly modest.
    Conclusion: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.
    MeSH term(s) Rats ; Male ; Animals ; Rats, Wistar ; Self Stimulation/physiology ; Streptozocin/toxicity ; Spatial Learning ; Alzheimer Disease/therapy ; Sirtuin 1/pharmacology ; Hippocampus ; MicroRNAs/genetics ; Maze Learning
    Chemical Substances Streptozocin (5W494URQ81) ; Sirtuin 1 (EC 3.5.1.-) ; MicroRNAs
    Language English
    Publishing date 2024-03-15
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1077443-9
    ISSN 1488-2434 ; 1180-4882
    ISSN (online) 1488-2434
    ISSN 1180-4882
    DOI 10.1503/jpn.230066
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    Zs.B 2105: Show issues Location:
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  5. Article ; Online: Material decomposition maps based calibration of dual energy CT scanners for proton therapy planning: a phantom study.

    Viar-Hernández, David / Vera-Sánchez, Juan Antonio / Schmidt-Santiago, Lucia / Rodriguez-Vila, Borja / Lorenzo-Villanueva, Isabel / Canals-de-Las-Casas, Elisabet / Castro-Novais, Juan / Maria Perez-Moreno, Juan / Cerrón-Campoo, Fernando / Malpica, Norberto / Torrado-Carvajal, Angel / Mazal, Alejandro

    Physics in medicine and biology

    2024  Volume 69, Issue 4

    Abstract: We introduce a new calibration method for dual energy CT (DECT) based on material decomposition (MD) maps, specifically iodine and water MD maps. The aim of this method is to provide the first DECT calibration based on MD maps. The experiments were ... ...

    Abstract We introduce a new calibration method for dual energy CT (DECT) based on material decomposition (MD) maps, specifically iodine and water MD maps. The aim of this method is to provide the first DECT calibration based on MD maps. The experiments were carried out using a general electric (GE) revolution CT scanner with ultra-fast kV switching and used a density phantom by GAMMEX for calibration and evaluation. The calibration process involves several steps. First, we tested the ability of MD values to reproduce Hounsfield unit (HU) values of single energy CT (SECT) acquisitions and it was found that the errors were below 1%, validating their use for HU reproduction. Next, the different definitions of computed
    MeSH term(s) Proton Therapy/methods ; Tomography, X-Ray Computed/methods ; Calibration ; Reproducibility of Results ; Tomography Scanners, X-Ray Computed ; Phantoms, Imaging
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ad2015
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    Zs.A 199: Show issues Location:
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  6. Article ; Online: Pemphigoid nodularis: An infrequent variant responding to rituximab.

    Vila-Payeras, Aina / Domínguez-Mahamud, Carolina / Terrasa-Sagristà, Fernando / Vila-Mas, Antonia / Parera-Amer, Elisabet / Nadal-Lladó, Cristina

    The Australasian journal of dermatology

    2020  Volume 61, Issue 4, Page(s) e438–e439

    MeSH term(s) Adult ; Dose-Response Relationship, Drug ; Glucocorticoids/adverse effects ; Humans ; Immunologic Factors/therapeutic use ; Pemphigoid, Bullous/drug therapy ; Pemphigoid, Bullous/etiology ; Rituximab/therapeutic use ; Treatment Outcome
    Chemical Substances Glucocorticoids ; Immunologic Factors ; Rituximab (4F4X42SYQ6)
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.13331
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    Zs.A 236: Show issues Location:
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  7. Article ; Online: Systemic B-cell lymphoma with skin manifestation clinically resembling granuloma annulare.

    Vila-Payeras, Aina / Terrasa-Sagristá, Fernando / Nadal-Lladó, Cristina / Parera-Amer, Elisabet

    Journal of cutaneous pathology

    2020  Volume 48, Issue 5, Page(s) 607–610

    MeSH term(s) Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/therapeutic use ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy/methods ; Bone Marrow/pathology ; Diagnosis, Differential ; Granuloma Annulare/diagnosis ; Granuloma Annulare/drug therapy ; Granuloma Annulare/pathology ; Humans ; Immunohistochemistry/methods ; Injections, Intralesional/methods ; Lymphoma, Large B-Cell, Diffuse/complications ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/pathology ; Male ; Neoplasm Staging/methods ; Skin Diseases/etiology ; Skin Diseases/pathology
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2020-11-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.13779
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    Zs.A 1043: Show issues Location:
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  8. Article ; Online: Transcriptional Analysis of Tightly Synchronized Plasmodium falciparum Intraerythrocytic Stages by RT-qPCR.

    Casas-Vila, Núria / Pickford, Anastasia K / Portugaliza, Harvie P / Tintó-Font, Elisabet / Cortés, Alfred

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2369, Page(s) 165–185

    Abstract: In Plasmodium falciparum, the parasite responsible for the most severe forms of human malaria, many fundamental processes are controlled at the transcriptional level. Studies on diverse aspects of basic parasite biology as well as molecular epidemiology ... ...

    Abstract In Plasmodium falciparum, the parasite responsible for the most severe forms of human malaria, many fundamental processes are controlled at the transcriptional level. Studies on diverse aspects of basic parasite biology as well as molecular epidemiology studies often rely on the ability to accurately measure transcript levels, but this is complicated by the cyclic expression patterns of the majority of malaria parasite genes. Here, we provide a complete workflow to measure transcript levels in P. falciparum intraerythrocytic blood stages, overcoming the confounding factors that are commonly encountered. The method described covers all the steps from synchronization of parasite cultures to reverse transcriptase quantitative PCR (RT-qPCR) analysis.
    MeSH term(s) Humans ; Malaria, Falciparum ; Plasmodium falciparum/genetics ; Reverse Transcriptase Polymerase Chain Reaction
    Language English
    Publishing date 2021-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1681-9_10
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  9. Article ; Online: Intracranial Self-stimulation of the Medial Forebrain Bundle Ameliorates Memory Disturbances and Pathological Hallmarks in an Alzheimer's Disease Model by Intracerebral Administration of Amyloid-β in Rats.

    Puig-Parnau, Irene / Garcia-Brito, Soleil / Vila-Soles, Laia / Riberas, Andrea / Aldavert-Vera, Laura / Segura-Torres, Pilar / Kádár, Elisabet / Huguet, Gemma

    Neuroscience

    2023  Volume 512, Page(s) 16–31

    Abstract: No curative or fully effective treatments are currently available for Alzheimer's disease (AD), the most common form of dementia. Electrical stimulation of deep brain areas has been proposed as a novel neuromodulatory therapeutic approach. Previous ... ...

    Abstract No curative or fully effective treatments are currently available for Alzheimer's disease (AD), the most common form of dementia. Electrical stimulation of deep brain areas has been proposed as a novel neuromodulatory therapeutic approach. Previous research from our lab demonstrates that intracranial self-stimulation (ICSS) targeting medial forebrain bundle (MFB) facilitates explicit and implicit learning and memory in rats with age or lesion-related memory impairment. At a molecular level, MFB-ICSS modulates the expression of plasticity and neuroprotection-related genes in memory-related brain areas. On this basis, we suggest that MFB could be a promising stimulation target for AD treatment. In this study, we aimed to assess the effects of MFB-ICSS on both explicit memory as well as the levels of neuropathological markers ptau and drebrin (DBN) in memory-related areas, in an AD rat model obtained by Aβ icv-injection. A total of 36 male rats were trained in the Morris water maze on days 26-30 after Aβ injection and tested on day 33. Results demonstrate that this Aβ model displayed spatial memory impairment in the retention test, accompanied by changes in the levels of DBN and ptau in lateral entorhinal cortex and hippocampus, resembling pathological alterations in early AD. Administration of MFB-ICSS treatment consisting of 5 post-training sessions to AD rats managed to reverse the memory deficits as well as the alteration in ptau and DBN levels. Thus, this paper reports both cognitive and molecular effects of a post-training reinforcing deep brain stimulation procedure in a sporadic AD model for the first time.
    MeSH term(s) Animals ; Male ; Rats ; Alzheimer Disease/therapy ; Amyloid beta-Peptides ; Disease Models, Animal ; Medial Forebrain Bundle/physiology ; Memory Disorders/therapy ; Rats, Wistar ; Spatial Memory/physiology ; Electric Stimulation Therapy/methods
    Chemical Substances Amyloid beta-Peptides
    Language English
    Publishing date 2023-01-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 196739-3
    ISSN 1873-7544 ; 0306-4522
    ISSN (online) 1873-7544
    ISSN 0306-4522
    DOI 10.1016/j.neuroscience.2023.01.005
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    Zs.A 1215: Show issues Location:
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  10. Article: Pemphigoid nodularis: An infrequent variant responding to rituximab

    Vila-Payeras, Aina / Domínguez-Mahamud, Carolina / Terrasa-Sagristà, Fernando / Vila-Mas, Antonia / Parera-Amer, Elisabet / Nadal-Lladó, Cristina

    Australas. j. dermatol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32408380
    Database COVID19

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