Article ; Online: Interactions between human immunodeficiency virus type 1 and polymorphonuclear neutrophils.
2013 Volume 6, Issue 1, Page(s) 13–20
Abstract: Polymorphonuclear neutrophils (PMN) are the most abundant circulating leukocytes. They represent a first line of innate immunity against a large panel of microbial pathogens, pending development of specific immune responses. The role of PMN in human ... ...
Abstract | Polymorphonuclear neutrophils (PMN) are the most abundant circulating leukocytes. They represent a first line of innate immunity against a large panel of microbial pathogens, pending development of specific immune responses. The role of PMN in human immunodeficiency virus type 1 (HIV-1) disease has mainly been investigated from the point of view of the increased susceptibility of HIV-1-infected patients to bacterial and fungal infections. However, it is now clear that the relationship between PMN and HIV-1 is far more complex. This review examines both the beneficial and the detrimental effects of PMN during HIV infection. |
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MeSH term(s) | Animals ; HIV Infections/immunology ; HIV-1/immunology ; Host-Pathogen Interactions ; Humans ; Neutrophils/immunology |
Language | English |
Publishing date | 2013-07-18 |
Publishing country | Switzerland |
Document type | Journal Article ; Review |
ZDB-ID | 2454158-8 |
ISSN | 1662-8128 ; 1662-811X |
ISSN (online) | 1662-8128 |
ISSN | 1662-811X |
DOI | 10.1159/000353588 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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