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Article: [Effect of corneal e-value on myopia control in children and adolescents with orthokeratology].

Xu, Q / Hu, Y Y / Wen, Y / Liu, G Y / Yang, Z P / Zhang, C C / Ding, M H / Bi, H S

Zhonghua yan ke za zhi] Chinese journal of ophthalmology

2024 Volume 60, Issue 4, Page(s) 330–336

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Male ; Female ; Child ; Humans ; Adolescent ; Retrospective Studies ; Contact Lenses ; Axial Length, Eye ; Orthokeratologic Procedures ; Myopia/therapy ; Corneal Topography ; Refraction, Ocular
Language	Chinese
Publishing date	2024-04-07
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604574-1
ISSN	0412-4081
ISSN	0412-4081
DOI	10.3760/cma.j.cn112142-20231122-00245
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Article: Aculeaxanthones A-E, new xanthones from the marine-derived fungus

Wu, Jun / Shui, Hua / Zhang, Mengke / Zeng, Yida / Zheng, Mingxin / Zhu, Kong-Kai / Wang, Shou-Bao / Bi, Hongkai / Hong, Kui / Cai, You-Sheng

Frontiers in microbiology

2023 Volume 14, Page(s) 1138830

Abstract: ... In this study, we report five new dimeric tetrahydroxanthones, aculeaxanthones A-E (: Methods: A part ...

Abstract	Introduction: Dimeric natural products are widespread in plants and microorganisms, which usually have complex structures and exhibit greater bioactivities than their corresponding monomers. In this study, we report five new dimeric tetrahydroxanthones, aculeaxanthones A-E ( Methods: A part of the culture was added to a total of 60 flasks containing 300 ml each of number II fungus liquid medium and culture 4 weeks in a static state at 28˚C. The liquid phase (18 L) and mycelia was separated from the fungal culture by filtering. A crude extract was obtained from the mycelia by ultrasound using acetone. To obtain a dry extract (18 g), the liquid phase combined with the crude extract were further extracted by EtOAc and concentrated in vacuo. The MIC of anaerobic bacteria was examined by a broth microdilution assay. To obtain MICs for aerobic bacteria, the agar dilution streak method recommended in Clinical and Laboratory Standards Institute document (CLSI) M07-A10 was used. Compounds 1-9 was tested against the Bel-7402, A-549 and HCT-116 cell lines according to MTT assay. Results and discussion: The structures of these compounds were elucidated on the base of 1D and 2D NMR and HR-ESIMS data, and the absolute configurations of the new xanthones
Language	English
Publishing date	2023-02-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1138830
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Article ; Online: Polyetheretherketone (PEEK) as a Potential Material for the Repair of Maxillofacial Defect Compared with E-poly(tetrafluoroethylene) (e-PTFE) and Silicone.

Bi, Xin / Li, Mingdong / Zhang, Yuchen / Yin, Ming / Che, Wuqiang / Bi, Zhenyu / Yang, Yuchao / Ouyang, Jun

ACS biomaterials science & engineering

2023 Volume 9, Issue 7, Page(s) 4328–4340

Abstract: Silicone and e-poly(tetrafluoroethylene) (e-PTFE) are the most commonly used artificial materials ... of maxillofacial bone defects lacks a theoretical basis. The microstructure and mechanical properties of e-PTFE ... and 12 weeks post-surgery. PEEK had a much higher Young's modulus than either e-PTFE or silicone ( ...

Abstract	Silicone and e-poly(tetrafluoroethylene) (e-PTFE) are the most commonly used artificial materials for repairing maxillofacial bone defects caused by facial trauma and tumors. However, their use is limited by poor histocompatibility, unsatisfactory support, and high infection rates. Polyetheretherketone (PEEK) has excellent mechanical strength and biocompatibility, but its application to the repair of maxillofacial bone defects lacks a theoretical basis. The microstructure and mechanical properties of e-PTFE, silicone, and PEEK were evaluated by electron microscopy, BOSE machine, and Fourier transformed infrared spectroscopy. Mouse fibroblast L929 cells were incubated on the surface of the three materials to assess cytotoxicity and adhesion. The three materials were implanted onto the left femoral surface of 90 male mice, and samples of the implants and surrounding soft tissues were evaluated histologically at 1, 2, 4, 8, and 12 weeks post-surgery. PEEK had a much higher Young's modulus than either e-PTFE or silicone (
MeSH term(s)	Maxillofacial Injuries/surgery ; Male ; Animals ; Mice ; Mice, Inbred C57BL ; Cell Line ; Polyesters ; Surface Properties ; Silicones ; Cell Adhesion ; Gait ; Prostheses and Implants
Chemical Substances	polyetheretherketone (31694-16-3) ; tetrafluoroethylene (OMW63Z518S) ; Polyesters ; Silicones
Language	English
Publishing date	2023-06-05
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2373-9878
ISSN (online)	2373-9878
DOI	10.1021/acsbiomaterials.2c00744
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Article ; Online: Molecular screening of Entamoeba spp. (E. histolytica, E. dispar, E. coli, and E. hartmanni) and Giardia intestinalis using PCR and sequencing

M. Tokoro / T. Mizuno / X. Bi / S.A. Lacante / C. Jiang / R.N. Makunja

MethodsX, Vol 11, Iss , Pp 102361- (2023)

2023

Abstract: ... from Kenyan children. The prevalences of the target species were as follows: E. histolytica (2/174, 1.1%), E ... dispar (20/174, 11.5%), E. coli (107/174, 61.5%), E. hartmanni (77/174, 44.3%), and G. intestinalis (54 ... for some cross-reactions between E. hartmanni detection primers and G. intestinalis, although the false-positive amplicons ...

Abstract	A wide range of intestinal protozoan parasites inhabit the human gut. To establish a more comprehensive molecular screening, we designed PCR-sequencing screening methods for Entamoeba spp., including commensal species, and Giardia intestinalis, and performed such methods using 174 stool samples collected from Kenyan children. The prevalences of the target species were as follows: E. histolytica (2/174, 1.1%), E. dispar (20/174, 11.5%), E. coli (107/174, 61.5%), E. hartmanni (77/174, 44.3%), and G. intestinalis (54/174, 31.0%). PCR amplicons specific to G. intestinalis was differentiated to assemblages A (8/174, 4.6%) and B (46/174, 26.4%). PCR specificity for Entamoeba spp. was quite high, except for some cross-reactions between E. hartmanni detection primers and G. intestinalis, although the false-positive amplicons were discernible by the band size. The 18S rRNA PCR primers that was designed by Monis et al. in 1999 for G. intestinalis, have specificity issue, therefore amplicon sequencing was essential not only to determine assemblage classifications but also to confirm the positive results by eliminating potential non-specific reactions. The detection sensitivity of both the Entamoeba universal PCR and the G. intestinalis PCR was more than 100 copies of the target loci, which is sufficient for detecting a single trophozoite or cyst of both species.
Keywords	PCR-sequencing screening methods for Entameoba spp. and Giardia intestinalis ; Science ; Q
Subject code	630
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article: Integration of e-learning approaches in a post-pandemic learning environment - Norwegian nursing students' recommendations from an action research study.

Karlsen, Karina / Aronsen, Charlotte / Bjørnnes, Therese Daleng / Harberg, Trine Bruun / Halland, Anita Nytræ / Holand, Thomas / Jakobsen, Lena / Kornbakk, Liv / Kvalshaug, Britt-Inger / Lian, Hilde / Nygård, Carina / Solsvik, Ann Kristin / Trømborg, Elisabeth / Emaus, Nina

Heliyon

2023 Volume 9, Issue 2, Page(s) e13331

Abstract: ... and e-learning strategies. The aim of the present study was to examine how future pedagogical ... the pandemic, we suggest that digital platforms and e-learning strategies facilitate nursing students learning ...

Abstract	The covid-19 pandemic has profoundly led to changes in use of digital platforms, online teaching, and e-learning strategies. The aim of the present study was to examine how future pedagogical approaches can promote constructive learning environments and facilitate nursing students learning processes in future post-pandemic scenarios based on an action research study, which were conducted through several steps from January 2021 through January 2022 in a Bachelor of Nursing program at UiT the Arctic University of Norway. Students from the 2020 enrollment were invited to focus group interviews in March 2021. The interviews were transcribed, and content analyzed, resulting in concrete advice, which were implemented for the next enrollment. Students from the 2021 enrollment were invited to similar focus groups, resulting in refined advice, which will be presented. The pandemic situation resulted in extensive use of digital platforms for the 2020 enrollment. Students from this cohort described shock and disappointment connected to their study start. They expected a new life, meeting new friends and to develop a student identity, but their expectations were broken. The loss of social connections led to isolation and a weak link to the program and to the nursing profession. They recommended integrated training of theoretical and practical skills in small groups combined with short, well-prepared digital lectures equivalent to "flipped classroom" approaches. Implementing their advice, the 2021 enrollment's experience became different. This group was prepared for extensive use of digital platforms and gave future advise on increased flexibility and balance between the various learning activities centered around the clinical sessions. Based on these experiences during the pandemic, we suggest that digital platforms and e-learning strategies facilitate nursing students learning in combination with active and social learning environments.
Language	English
Publishing date	2023-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e13331
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Article ; Online: Engineered Design of the E-Helix Structure on Ferritin Nanoparticles.

Qu, Yiran / Davey, Kenneth / Sun, Yan / Middelberg, Anton / Bi, Jingxiu

ACS applied bio materials

2022 Volume 5, Issue 7, Page(s) 3167–3179

Abstract: ... insertion affects ferritin protein stability. The E-helix at the C-terminus has attracted interest ... of the E-helix at the C-terminus of engineered human ferritin heavy chain (F ...

Abstract	Insertion of an immunogenic epitope at the C-terminus of ferritin has shown the potential to produce a stable and efficacious vaccine. There is however limited understanding of how C-terminus insertion affects ferritin protein stability. The E-helix at the C-terminus has attracted interest because there are contradictory reports as to whether it has a role in protein stabilization. Here, we report, for the first time, combining molecular dynamics simulation (MDS) with experiment to engineer the design of the E-helix at the C-terminus of engineered human ferritin heavy chain (F
MeSH term(s)	Epitopes ; Ferritins/genetics ; Humans ; Nanoparticles ; Protein Folding ; Protein Structure, Secondary
Chemical Substances	Epitopes ; Ferritins (9007-73-2)
Language	English
Publishing date	2022-06-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2576-6422
ISSN (online)	2576-6422
DOI	10.1021/acsabm.2c00154
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Article ; Online: HOXA10 improves endometrial receptivity by upregulating E-cadherin†.

Bi, Yin / Huang, Weiyu / Yuan, Lifang / Chen, Saiqiong / Liao, Shengbin / Fu, Xiaoqian / Liu, Bo / Yang, Yihua

Biology of reproduction

2022 Volume 106, Issue 5, Page(s) 992–999

Abstract: ... recurrent miscarriage, the expression levels of homeobox A10 and E-cadherin were positively correlated. To explore ... whether homeobox A10 regulates E-cadherin during endometrial receptivity establishment, Ishikawa and RL95-2 cells ... of homeobox A10. The expression levels of homeobox A10 and E-cadherin were measured by western blot and ...

Abstract	In the endometrium of women with recurrent implantation failure and unexplained recurrent miscarriage, the expression levels of homeobox A10 and E-cadherin were positively correlated. To explore whether homeobox A10 regulates E-cadherin during endometrial receptivity establishment, Ishikawa and RL95-2 cells were transfected with target-specific small interfering RNA (siRNA) and overexpression plasmid of homeobox A10. The expression levels of homeobox A10 and E-cadherin were measured by western blot and quantitative Real-time Polymerase Chain Reaction (qRT-PCR). Attachment assay of JEG-3 spheroids to endometrial cells were conducted to explore the adhesive functions after homeobox A10 interfered. Chromatin immunoprecipitation assays and dual luciferase reporter were used to investigate the regulatory mechanism of homeobox A10. The CD1 mice were transfected with si-homeobox A10 to confirm these results in vivo. In Ishikawa and RL95-2 cells, the expression of E-cadherin was positively correlated with homeobox A10 when it was silenced/overexpressed. Consistently, the adhesion of endometrial epithelium cells and trophoblast cells was inhibited after homeobox A10 was silenced, and exogenous restoration of E-cadherin expression reversed this effect to some extent. Homeobox A10 regulates the expression of E-cadherin by directly binding to a conserved motif (TGTACTAAAAA) located in the E-cadherin promoter region. In addition, after knockdown of homeobox A10 in CD1 mice, both the implantation and live birth rates were decreased. In conclusion, homeobox A10 can bind to the E-cadherin promoter region and directly regulate its expression, thereby improving endometrial receptivity and subsequently increasing the embryo adhesion and implantation.
MeSH term(s)	Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Line, Tumor ; Embryo Implantation/physiology ; Endometrium/metabolism ; Female ; Homeobox A10 Proteins/genetics ; Humans ; Mice ; RNA, Small Interfering/genetics
Chemical Substances	Antigens, CD ; CDH1 protein, human ; Cadherins ; Homeobox A10 Proteins ; RNA, Small Interfering ; HOXA10 protein, human (140441-81-2)
Language	English
Publishing date	2022-03-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	1118-6
ISSN	1529-7268 ; 0006-3363
ISSN (online)	1529-7268
ISSN	0006-3363
DOI	10.1093/biolre/ioac007
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Article ; Online: Tetrabromobisphenol-A/S and their derivatives in surface particulates from workshop floors of three representative e-waste recycling sites in China.

Yang, Hui / Luo, Xiao-Jun / He, Jia-Zhuo / Zeng, Yan-Hong / Mai, Bi-Xian / Wang, Li-Zhong / Bi, Xiang

Environmental research

2024 , Page(s) 118915

Abstract: Surface particulates collected from the workshop floors of three major e-waste recycling sites ... their derivatives to investigate the environmental pollution caused by e-waste recycling activities. Mean ... The composition profiles of TBBPA/S analogs differed significantly among three e-waste sites. Similarly ...

Abstract	Surface particulates collected from the workshop floors of three major e-waste recycling sites (Taizhou, Qingyuan, and Guiyu) in China were analyzed for tetrabromobisphenol A/S (TBBPA/S) and their derivatives to investigate the environmental pollution caused by e-waste recycling activities. Mean concentrations of total TBBPA/S analogs in surface particulates were 31,471-116,059 ng/g dry weight (dw). TBBPA, TBBPA-BGE, and TBBPA-BDBPE were the most frequently detected in particulates with average concentration ranges of 17,929-78,406, 5,601-15,842, and 5,929-21,383 ng/g dw, respectively. Meanwhile, TBBPA, TBBPA-BGE, and TBBPA-BDBPE were the most abundant TBBPA/S analogs, accounting for around 96% of the total. The composition profiles of TBBPA/S analogs differed significantly among three e-waste sites. Similarly, principal component analysis uncovered different pollution patterns among different sites. The discrepancy in the profiles of TBBPA/S analogs largely relied on the e-waste types recycled in different areas. E-waste recycling led to the release of TBBPA/S analogs, and TBBPA/S analogs produced differentiation during migration from source (surface particulates) to nearby soil. More researches are necessary to find a definite relationship between pollution status and e-waste types and study differentiation behavior of TBBPA/S analogs in migration and diffusion from source to environmental medium.
Language	English
Publishing date	2024-04-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2024.118915
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Article ; Online: Search for Dark Matter Annihilation Signals in the H.E.S.S. Inner Galaxy Survey.

Abdalla, H / Aharonian, F / Benkhali, F Ait / Angüner, E O / Armand, C / Ashkar, H / Backes, M / Baghmanyan, V / Martins, V Barbosa / Batzofin, R / Becherini, Y / Berge, D / Bernlöhr, K / Bi, B / Böttcher, M / Bolmont, J / de Lavergne, M de Bony / Brose, R / Brun, F /

Cangemi, F / Caroff, S / Cerruti, M / Chand, T / Chen, A / Cotter, G / Mbarubucyeye, J Damascene / Devin, J / Djannati-Ataï, A / Dmytriiev, A / Doroshenko, V / Egberts, K / Fiasson, A / de Clairfontaine, G Fichet / Fontaine, G / Funk, S / Gabici, S / Giavitto, G / Glawion, D / Glicenstein, J F / Grondin, M-H / Hinton, J A / Hofmann, W / Holch, T L / Holler, M / Horns, D / Huang, Zhiqiu / Jamrozy, M / Jankowsky, F / Kasai, E / Katarzyński, K / Katz, U / Khélifi, B / Kluźniak, W / Komin, Nu / Kosack, K / Kostunin, D / Lamanna, G / Lemoine-Goumard, M / Lenain, J-P / Leuschner, F / Lohse, T / Luashvili, A / Lypova, I / Mackey, J / Malyshev, D / Marandon, V / Marchegiani, P / Martí-Devesa, G / Marx, R / Maurin, G / Meyer, M / Mitchell, A / Moderski, R / Montanari, A / Moulin, E / Muller, J / de Naurois, M / Niemiec, J / Noel, A Priyana / Ohm, S / Olivera-Nieto, L / Wilhelmi, E de Ona / Ostrowski, M / Panny, S / Panter, M / Parsons, R D / Peron, G / Poireau, V / Prokoph, H / Pühlhofer, G / Punch, M / Quirrenbach, A / Reichherzer, P / Reimer, A / Reimer, O / Renaud, M / Rieger, F / Rowell, G / Rudak, B / Ricarte, H Rueda / Ruiz-Velasco, E / Sahakian, V / Salzmann, H / Santangelo, A / Sasaki, M / Schüssler, F / Schutte, H M / Schwanke, U / Senniappan, M / Shapopi, J N S / Sol, H / Specovius, A / Spencer, S / Stawarz, Ł / Stegmann, C / Steinmassl, S / Steppa, C / Takahashi, T / Tanaka, T / Terrier, R / Thorpe-Morgan, C / Tluczykont, M / Tsirou, M / Tsuji, N / Uchiyama, Y / van Eldik, C / Veh, J / Vink, J / Wagner, S J / White, R / Wierzcholska, A / Wong, Yu Wun / Zacharias, M / Zargaryan, D / Zdziarski, A A / Zech, A / Zhu, S J / Zouari, S / Żywucka, N

Physical review letters

2022 Volume 129, Issue 11, Page(s) 111101

Abstract: ... observations from an unprecedented γ-ray survey of the Galactic Center (GC) region, i.e., the Inner Galaxy ... Survey, at very high energies (≳100 GeV) performed with the H.E.S.S. array of five ground-based ... With the H.E.S.S. Inner Galaxy Survey, ground-based γ-ray observations thus probe ⟨σv⟩ values expected ...

Abstract	The central region of the Milky Way is one of the foremost locations to look for dark matter (DM) signatures. We report the first results on a search for DM particle annihilation signals using new observations from an unprecedented γ-ray survey of the Galactic Center (GC) region, i.e., the Inner Galaxy Survey, at very high energies (≳100 GeV) performed with the H.E.S.S. array of five ground-based Cherenkov telescopes. No significant γ-ray excess is found in the search region of the 2014-2020 dataset and a profile likelihood ratio analysis is carried out to set exclusion limits on the annihilation cross section ⟨σv⟩. Assuming Einasto and Navarro-Frenk-White (NFW) DM density profiles at the GC, these constraints are the strongest obtained so far in the TeV DM mass range. For the Einasto profile, the constraints reach ⟨σv⟩ values of 3.7×10^{-26} cm^{3} s^{-1} for 1.5 TeV DM mass in the W^{+}W^{-} annihilation channel, and 1.2×10^{-26} cm^{3} s^{-1} for 0.7 TeV DM mass in the τ^{+}τ^{-} annihilation channel. With the H.E.S.S. Inner Galaxy Survey, ground-based γ-ray observations thus probe ⟨σv⟩ values expected from thermal-relic annihilating TeV DM particles.
Language	English
Publishing date	2022-09-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.129.111101
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Article ; Online: Older Travelers’ E-Loyalty

Yahua Bi / Insin Kim

Sustainability, Vol 12, Iss 1, p

The Roles of Service Convenience and Social Presence in Travel Websites

2020 Volume 410

Abstract: ... websites from the perspective of older travelers, and if older travelers’ satisfaction enhances e-loyalty ... The older travelers’ satisfaction with travel websites has a positive impact on e-loyalty. Additionally ... e-commerce service in the field of tourism and provides practitioners with effective ways to attract older ...

Abstract	The research aims to examine what service convenience factors drive customer satisfaction in travel websites from the perspective of older travelers, and if older travelers’ satisfaction enhances e-loyalty. Additionally, drawing on socioemotional selectivity theory, this study argues that the social presence in travel websites plays a significant moderating role in increasing older travelers’ satisfaction. To empirically verify the conceptual model, an online survey was conducted targeting older travelers aged over 50 in the USA who have purchased products via travel websites. The data from 308 older travelers were analyzed, and the results revealed four dimensions of service convenience positively influence satisfaction. Unexpectedly, access convenience and transaction convenience do not influence older travelers’ satisfaction. The older travelers’ satisfaction with travel websites has a positive impact on e-loyalty. Additionally, social presence amplifies the effect of post-purchase convenience on satisfaction. The current research makes a significant contribution to understanding older travelers’ perceptions and behaviors for using e-commerce service in the field of tourism and provides practitioners with effective ways to attract older travelers for sustainable management of travel websites.
Keywords	e-loyalty ; service convenience ; satisfaction ; social presence ; older travelers ; travel website ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	380
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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