Article ; Online: Sarcoidosis cardíaca como causa muy infrecuente de muerte súbita en pacientes jóvenes asintomáticos.
2023 Volume 56, Issue 4, Page(s) 284–288
Abstract: Cardiac involvement in sarcoidosis has been described in both symptomatic and asymptomatic patients. The aim of this report is to further the understanding of sarcoidosis and its clinical presentation. We report the autopsy and toxicology results of two ... ...
| Title translation | Cardiac sarcoidosis as an infrequent cause of sudden death in asymptomatic young patients. |
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| Abstract | Cardiac involvement in sarcoidosis has been described in both symptomatic and asymptomatic patients. The aim of this report is to further the understanding of sarcoidosis and its clinical presentation. We report the autopsy and toxicology results of two cases of sudden death in young men. A 37-year-old male had generalized sarcoidosis, in mediastinal glands and intramyocardial sarcoid granulomas in the left ventricle, which had caused a 14mm thickening of the ventricular wall and a secondary dilated myocardiopathy causing sudden death. A 27-year-old male had extensive sarcoidosis of the lungs and mediastinum. Granulomas with a fibrotic background were found in the cardiac wall which could have originated an arrhythmogenic mechanism causing sudden death. Post-mortem study including careful examination of cardiac conduction pathways are vital to ascertain the cause of sudden death. |
| MeSH term(s) | Male ; Humans ; Adult ; Cardiomyopathies ; Death, Sudden, Cardiac/etiology ; Sarcoidosis/complications ; Sarcoidosis/diagnosis ; Granuloma ; Autopsy |
| Language | Spanish |
| Publishing date | 2023-06-09 |
| Publishing country | Spain |
| Document type | Case Reports ; English Abstract |
| ZDB-ID | 2463888-2 |
| ISSN | 1988-561X ; 1988-561X |
| ISSN (online) | 1988-561X |
| ISSN | 1988-561X |
| DOI | 10.1016/j.patol.2023.04.002 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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