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  1. Article: Neuroplasticity of pain processing and motor control in CAI patients: A UK Biobank study with clinical validation.

    Wang, Yiran / Li, Qianru / Xue, Xiao'ao / Xu, Xiaoyun / Tao, Weichu / Liu, Sixu / Li, Yunyi / Wang, He / Hua, Yinghui

    Frontiers in molecular neuroscience

    2023  Volume 16, Page(s) 1096930

    Abstract: Background: Pain plays an important role in chronic ankle instability (CAI), and prolonged pain ... related brain regions between healthy controls and patients with CAI, and explore the relationship between ... a validation dataset of 15 patients with CAI and 15 healthy controls. All participants underwent resting-state ...

    Abstract Background: Pain plays an important role in chronic ankle instability (CAI), and prolonged pain may be associated with ankle dysfunction and abnormal neuroplasticity.
    Purpose: To investigate the differences in resting-state functional connectivity among the pain-related brain regions and the ankle motor-related brain regions between healthy controls and patients with CAI, and explore the relationship between patients' motor function and pain.
    Study design: A cross-database, cross-sectional study.
    Methods: This study included a UK Biobank dataset of 28 patients with ankle pain and 109 healthy controls and a validation dataset of 15 patients with CAI and 15 healthy controls. All participants underwent resting-state functional magnetic resonance imaging scanning, and the functional connectivity (FC) among the pain-related brain regions and the ankle motor-related brain regions were calculated and compared between groups. The correlations between the potentially different functional connectivity and the clinical questionnaires were also explored in patients with CAI.
    Results: The functional connection between the cingulate motor area and insula significantly differed between groups in both the UK Biobank (
    Conclusion: A reduced functional connection between the cingulate motor area and the insula was present in patients with CAI, which was also directly correlated with reduction in the level of patient physical activity.
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452967-9
    ISSN 1662-5099
    ISSN 1662-5099
    DOI 10.3389/fnmol.2023.1096930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Parametric Study on Low-Velocity Impact (LVI) Damage and Compression after Impact (CAI) Strength of Composite Laminates.

    Guo, Shuangxi / Li, Xueqin / Liu, Tianwei / Bu, Guangyu / Bai, Jiangbo

    Polymers

    2022  Volume 14, Issue 23

    Abstract: ... CAI) strength was established based on a subroutine of the material constitutive relationship and ... the CAI strength were predicted. The predicted results were compared with the experimental ones. It is ... shown that the predicted value of the CAI strength is in good agreement with the experimental result ...

    Abstract A full-scale model for predicting low-velocity impact (LVI) damage and compression after impact (CAI) strength was established based on a subroutine of the material constitutive relationship and the cohesive elements. The dynamic responses of the laminate under impact load and damage propagation under a compressive load were presented. The influences of impact energy and ply thickness on the impact damage and the CAI strength were predicted. The predicted results were compared with the experimental ones. It is shown that the predicted value of the CAI strength is in good agreement with the experimental result. As the impact energy reaches a certain value, the CAI strength no longer decreases with the increase in the impact energy. Decreasing the ply thickness can effectively improve the damage resistance and CAI strength.
    Language English
    Publishing date 2022-11-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14235200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effect of Cisplatin Arterial Infusion (CAI) on Primary Nonmetastatic Pelvic Osteosarcoma: A Preliminary Study.

    Hu, Xuantao / Chen, Xia / Li, Tao / Liu, Zicheng / Guo, Xiaoning / Ouyang, Zhengxiao

    Cancer management and research

    2021  Volume 13, Page(s) 1491–1503

    Abstract: Purpose: The critical role of arterial infusion chemotherapy in the multimodal treatment of extremity bone cancer has been investigated extensively, but few studies have focused on pelvic osteosarcoma. Therefore, we attempted to evaluate the clinical ... ...

    Abstract Purpose: The critical role of arterial infusion chemotherapy in the multimodal treatment of extremity bone cancer has been investigated extensively, but few studies have focused on pelvic osteosarcoma. Therefore, we attempted to evaluate the clinical significance of arterial infusion chemotherapy in the treatment of pelvic osteosarcoma.
    Patients and methods: We combined a cisplatin arterial infusion regimen with multidrug systematic chemotherapy as a neoadjuvant protocol for the treatment of pelvic osteosarcoma. The course number and dosage of cisplatin arterial infusion were adjusted to achieve a maximal tumor response evaluated by contrast-enhanced MRI per RECIST 1.1. Good responders received the same systematic combination for postoperative chemotherapy, and poor responders received second-line therapy. Twelve patients with nonmetastatic high-grade pelvic osteosarcoma were included. Survival, chemotherapy response and adverse events data were analyzed.
    Results: The mean follow-up period was 56.1 months. Four patients died of refractory tumor progression, and 1 patient with local recurrence had no evidence of disease for 27 months after receiving secondary amputation and resection. Kaplan-Meier survival analysis demonstrated a 57.8% overall survival and 52.5% event-free survival rate at 5 years. Eight of 12 patients had a >90% tumor necrosis rate according to histopathologic examinations. The rates of local adverse events were lower than those reported for extremity osteosarcoma.
    Conclusion: Our study initially indicated that the cisplatin arterial infusion regimen was a potential therapy with good tolerance in the treatment of pelvic osteosarcoma.
    Language English
    Publishing date 2021-02-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2508013-1
    ISSN 1179-1322
    ISSN 1179-1322
    DOI 10.2147/CMAR.S294677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Comment on Cai et al. Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China. Diabetes Care 2020;43:1392–1398 / Reply

    He, Zebao / Li, Jie / Cai, Qingxian / Chen, Jun / Xu, Lin

    Diabetes Care

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #861593
    Database COVID19

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  5. Article ; Online: Parametric Study on Low-Velocity Impact (LVI) Damage and Compression after Impact (CAI) Strength of Composite Laminates

    Shuangxi Guo / Xueqin Li / Tianwei Liu / Guangyu Bu / Jiangbo Bai

    Polymers, Vol 14, Iss 5200, p

    2022  Volume 5200

    Abstract: ... CAI) strength was established based on a subroutine of the material constitutive relationship and ... the CAI strength were predicted. The predicted results were compared with the experimental ones. It is ... shown that the predicted value of the CAI strength is in good agreement with the experimental result ...

    Abstract A full-scale model for predicting low-velocity impact (LVI) damage and compression after impact (CAI) strength was established based on a subroutine of the material constitutive relationship and the cohesive elements. The dynamic responses of the laminate under impact load and damage propagation under a compressive load were presented. The influences of impact energy and ply thickness on the impact damage and the CAI strength were predicted. The predicted results were compared with the experimental ones. It is shown that the predicted value of the CAI strength is in good agreement with the experimental result. As the impact energy reaches a certain value, the CAI strength no longer decreases with the increase in the impact energy. Decreasing the ply thickness can effectively improve the damage resistance and CAI strength.
    Keywords low-velocity impact ; compression after impact ; composite ; delamination ; Organic chemistry ; QD241-441
    Subject code 306
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Bacterial community and composition in Jiang-shui and Suan-cai revealed by high-throughput sequencing of 16S rRNA.

    Liu, Zhanggen / Li, Junyi / Wei, Benliang / Huang, Tao / Xiao, Yangsheng / Peng, Zhen / Xie, Mingyong / Xiong, Tao

    International journal of food microbiology

    2019  Volume 306, Page(s) 108271

    Abstract: Fermented vegetables have a long history in many cultures. Jiang-shui and Suan-cai are two ... to identify the bacterial community structure of Jiang-shui and Suan-cai in this study. Subsequently ... Proteobacteria were the dominant phyla in both Jiang-shui and Suan-cai. However, Lactobacillus was the main genus ...

    Abstract Fermented vegetables have a long history in many cultures. Jiang-shui and Suan-cai are two of the most well-known instances in North China. They are made by a process of natural lactic acid fermentation. However, they have the different characteristics, i.e. acidity, taste and flavor, which are influenced by the specific bacterial community. Therefore, we used high-throughput sequencing methods to identify the bacterial community structure of Jiang-shui and Suan-cai in this study. Subsequently, we figured out the bacterial differences of these two products using the statistical analysis. Firmicutes and Proteobacteria were the dominant phyla in both Jiang-shui and Suan-cai. However, Lactobacillus was the main genus in Jiang-shui samples, whereas both Lactobacillus and Pediococcus were the major genera in the Suan-cai samples. At the species level, Lactobacillus amylolyticus, Lactobacillus fermentum and Lactobacillus pontis were the major species in Jiang-shui samples, while Pediococcus parvulus, Lactobacillus coryniformis, Lactobacillus pentosus and Lactobacillus parabrevis were the dominant species in the Suan-cai samples. These results suggested that Jiang-shui and Suan-cai had their own unique bacterial community, leading to the specific characteristics. Furthermore, the bacterial communities of both fermented vegetables varied at different locations. This study revealed the flora present in the Jiang-shui and the Suan-cai, providing a deep insight of the microbial species of Chinese fermented vegetables and guidance for the production of the Jiang-shui and the Suan-cai.
    MeSH term(s) China ; Fermentation ; Fermented Foods/microbiology ; Flavoring Agents ; Food Microbiology ; High-Throughput Nucleotide Sequencing ; Lactic Acid/metabolism ; Lactobacillus/genetics ; Lactobacillus/isolation & purification ; Pediococcus/genetics ; Pediococcus/isolation & purification ; Proteobacteria/genetics ; Proteobacteria/isolation & purification ; RNA, Ribosomal, 16S/genetics ; Vegetables/microbiology
    Chemical Substances Flavoring Agents ; RNA, Ribosomal, 16S ; Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2019-07-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 87122-9
    ISSN 1879-3460 ; 0168-1605
    ISSN (online) 1879-3460
    ISSN 0168-1605
    DOI 10.1016/j.ijfoodmicro.2019.108271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: An Integrated Analysis of Transcriptome and Metabolism Reveals an Inhibitory Effect of Low Light on Anthocyanin Biosynthesis in Purple cai-tai (Brassicarapa L. var. purpurea)

    Guo, Juxian / Wu, Tingquan / Fu, Mei / Li, Guihua / Luo, Wenlong / Kang, Yunyan / Wang, Tingqin

    Horticulturae. 2022 June 22, v. 8, no. 7

    2022  

    Abstract: ... in crop production. This condition inhibits the petiole anthocyanin synthesis and even its tastes in purple cai-tai ... on anthocyanin synthesis in purple cai-tai petiole is less reported. In this study, we performed an integrated ... acclimation in a purple cai-tai cultivar, XH1. Results shows that anthocyanin is obviously repressed by low ...

    Abstract Low light caused by industrial development and environment change has become a limitation in crop production. This condition inhibits the petiole anthocyanin synthesis and even its tastes in purple cai-tai (Brassicarapa L. var. purpurea); however, the molecular basis of the inhibitory effects by low light on anthocyanin synthesis in purple cai-tai petiole is less reported. In this study, we performed an integrated analysis of transcriptomes and metabolisms to decipher key genes and/or metabolites that responsible for low light acclimation in a purple cai-tai cultivar, XH1. Results shows that anthocyanin is obviously repressed by low light treatment, and consistently the structural genes related to the anthocyanin biosynthesis pathway is significantly enriched in the list of differentially expressed genes according to both GO and KEGG analysis. Furthermore, the amounts of some metabolites related to anthocyanin are dramatically decreased under low light treatment, such as cyanindin 3-O-glucoside chloride, cyanindin O-syringic acid, and cyanidin 3-O-rutinoside. In addition, we found that five transcription factors in TCP gene family especially BrTCP15 is substantially downregulated by low light treatments. The expression pattern of BrTCP15 in response to low light treatment was further confirmed by qPCR. This study reports the inhibitory effects of the anthocyanin biosynthesis pathway and BrTCP15 by low light treatments, and extends our knowledge on regulatory mechanism of the anthocyanin biosynthetic pathway in response to low light in B. rapa L.
    Keywords acclimation ; anthocyanins ; biochemical pathways ; biosynthesis ; chlorides ; crop production ; cultivars ; cyanidin ; gene expression regulation ; industrialization ; metabolites ; petioles ; transcriptome
    Language English
    Dates of publication 2022-0622
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2813983-5
    ISSN 2311-7524
    ISSN 2311-7524
    DOI 10.3390/horticulturae8070566
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Comment on Cai et al. Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China. Diabetes Care 2020;43:1392-1398.

    He, Zebao / Li, Jie

    Diabetes care

    2020  Volume 43, Issue 10, Page(s) e160–e161

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus Infections ; Diabetes Mellitus ; Humans ; Obesity/epidemiology ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dc20-1195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Fermentation characteristics and bacterial dynamics during Chinese sauerkraut fermentation by Lactobacillus curvatus LC-20 under varied salt concentrations reveal its potential in low-salt suan cai production.

    He, Jiale / Li, Fengzi / Wang, Yan / Wu, Hao / Yang, Hongyan

    Journal of bioscience and bioengineering

    2021  Volume 132, Issue 1, Page(s) 33–40

    Abstract: ... such as suan cai, a popular traditional fermented food in China. It is vital to systematically investigate ... the effects of salt concentrations on fermented suan cai for high fermentation quality and large-scale ... production. We elucidated the effects of salt concentrations on Lactobacillus curvatus (LC-20) and suan cai ...

    Abstract Salt profoundly affects the physicochemical properties and microbial abundance of fermented foods such as suan cai, a popular traditional fermented food in China. It is vital to systematically investigate the effects of salt concentrations on fermented suan cai for high fermentation quality and large-scale production. We elucidated the effects of salt concentrations on Lactobacillus curvatus (LC-20) and suan cai during fermentation, and found that salt (0-1%) favoured an increase in LC-20 growth and a decrease in pH (salt: 0-2%). For suan cai fermentation, the results from sensory scoring judged 1% salt treatment the highest. Salt concentration also affected the nitrite content of the fermentation system with peak nitrite values in low salt treatments being significantly higher on the first day, and gradually decreasing to similar levels. After fermentation, the total titratable acid and lactic acid concentrations in the 0-1% treatments were higher (p < 0.05) than those in 2-5% treatments. The colony forming units of lactic acid bacteria increased initially and then decreased after 6 d of fermentation. At the phylum level, Firmicutes and Proteobacteria were predominant in all treatments, and at the genus level, Lactobacillus dominated the fermentation. Other lactic acid bacteria such as Lactococcus and Weissella were also detected. Quantitative PCR showed DNA concentration of LC-20 at 0.5-2% salt treatments were higher than that in other treatments and L. curvatus was the dominant microorganism during fermentation. Hence, we conclude that L. curvatus could be used for suan cai product at low salt concentrations.
    MeSH term(s) Brassica/chemistry ; Brassica/microbiology ; Dose-Response Relationship, Drug ; Fermentation/drug effects ; Fermented Foods and Beverages/microbiology ; Food Microbiology ; Lactobacillus/drug effects ; Lactobacillus/metabolism ; Sodium Chloride/pharmacology
    Chemical Substances Sodium Chloride (451W47IQ8X)
    Language English
    Publishing date 2021-04-15
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1465387-4
    ISSN 1347-4421 ; 1389-1723
    ISSN (online) 1347-4421
    ISSN 1389-1723
    DOI 10.1016/j.jbiosc.2021.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Professor LUO Cai-gui's experience of using acupoint "Baliao" for treatment of low back pain].

    Lu, Qun-Wen / Wang, Min-Yu / Li, Qing-Bing / Wan, Yi-Wen / Shi, Da-Wei / Liu, Zhong-Xing / Luo, Jian / Luo, Cai-Gui

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2014  Volume 34, Issue 12, Page(s) 1225–1227

    Abstract: Professor LUO Cai-gui's experience of acupuncture at acupoint "Baliao" with twisting manipulation ...

    Abstract Professor LUO Cai-gui's experience of acupuncture at acupoint "Baliao" with twisting manipulation for treatment of low back pain is introduced. This method has significant efficacy on improving low back pain and numbness of lower extremities, which is characterized with short-time manipulation, quick de-qi and long effective time. The acupuncture methods, manipulations, precautions, etc. are elaborated in details. A typical case is added.
    MeSH term(s) Acupuncture Points ; Acupuncture Therapy/instrumentation ; Acupuncture Therapy/methods ; Humans ; Low Back Pain/therapy ; Male ; Middle Aged
    Language Chinese
    Publishing date 2014-12
    Publishing country China
    Document type Case Reports ; English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 0255-2930
    ISSN 0255-2930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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