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  1. Article ; Online: A half-century of developments in the field of antithrombotics-A tribute to Jack Hirsh.

    Bounameaux, Henri / Perrier, Arnaud

    European journal of internal medicine

    2020  Volume 75, Page(s) 23–24

    MeSH term(s) Fibrinolytic Agents ; Humans
    Chemical Substances Fibrinolytic Agents
    Language English
    Publishing date 2020-02-25
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.02.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2608: Show issues Location:
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  2. Article ; Online: L'interniste face à l'embolie pulmonaire.

    Bounameaux, H

    La Revue de medecine interne

    2011  Volume 32 Suppl 2, Page(s) S247–8

    Title translation Pulmonary embolism and internal medicine.
    MeSH term(s) Algorithms ; Diagnostic Techniques and Procedures ; Humans ; Internal Medicine/methods ; Internal Medicine/trends ; Physicians ; Professional Practice ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/etiology ; Pulmonary Embolism/therapy
    Language French
    Publishing date 2011-12
    Publishing country France
    Document type Journal Article
    ZDB-ID 604679-4
    ISSN 1768-3122 ; 0248-8663
    ISSN (online) 1768-3122
    ISSN 0248-8663
    DOI 10.1016/j.revmed.2011.09.013
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    Zs.B 2451: Show issues Location:
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  3. Book: Deep venous thrombosis

    Bounameaux, Henri

    an overview

    (VASA : Suppl. ; 25)

    1988  

    Author's details H. Bounameaux
    Series title VASA : Suppl. ; 25
    Vasa
    VASA ; Suppl.
    Collection Vasa
    VASA ; Suppl.
    Keywords Thrombophlebitis ; Venenthrombose
    Subject Phlebothrombose ; Tiefe Phlebothrombose ; Tiefe Venenthrombose ; Tiefe Beinvenenthrombose
    Size 28 S. : graph. Darst.
    Publisher Huber
    Publishing place Bern
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT003296051
    ISBN 3-456-81758-4 ; 978-3-456-81758-3
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 808 -Suppl.25- verfügbar in Königswinter Königswinter

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  4. Article ; Online: Contemporary management of pulmonary embolism: the answers to ten questions.

    Bounameaux, H

    Journal of internal medicine

    2010  Volume 268, Issue 3, Page(s) 218–231

    Abstract: Pulmonary embolism (PE) cannot be diagnosed solely on a clinical basis, because of the lack of sensitivity and specificity of clinical signs and symptoms. Pulmonary angiography is invasive and resource demanding. Because the prevalence of PE is ... ...

    Abstract Pulmonary embolism (PE) cannot be diagnosed solely on a clinical basis, because of the lack of sensitivity and specificity of clinical signs and symptoms. Pulmonary angiography is invasive and resource demanding. Because the prevalence of PE is relatively low (20% or less) amongst individuals who are clinically suspected of having the disease, submitting all of them to imaging (multi-detector CT angiography or ventilation/perfusion lung scintigraphy) would not be cost-effective. Therefore, diagnostic algorithms have been developed that include clinical probability assessment and D-dimer measurement to select the patients who require noninvasive imaging. Once the diagnosis is suspected or confirmed, therapy must be started to avoid potentially fatal recurrence. Treatment starts for an initial 3-month period with a 5-day course of parenteral unfractionated or low-molecular-weight heparin or fondaparinux overlapping with and followed by oral vitamin K antagonists monitored to maintain an international normalized ratio of 2-3. This initial period of 3 months may then be followed by a long-term secondary prevention period in patients who experience an idiopathic thromboembolic event and are at low risk of bleeding. New oral anticoagulants that do require patient monitoring and might exhibit a more favourable benefit-risk balance are currently under extensive clinical testing and might change the situation in the near future. A critical appraisal of the contemporary management of suspected PE is given in this overview with the discussion of 10 practical questions.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Algorithms ; Anticoagulants/therapeutic use ; Biomarkers/blood ; Drug Administration Schedule ; Fibrin Fibrinogen Degradation Products/analysis ; Humans ; Middle Aged ; Prognosis ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/drug therapy ; Tomography, X-Ray Computed/methods
    Chemical Substances Anticoagulants ; Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Language English
    Publishing date 2010-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 96274-0
    ISSN 1365-2796 ; 0954-6820
    ISSN (online) 1365-2796
    ISSN 0954-6820
    DOI 10.1111/j.1365-2796.2010.02254.x
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  5. Article: The novel anticoagulants: entering a new era.

    Bounameaux, H

    Swiss medical weekly

    2008  Volume 139, Issue 5-6, Page(s) 60–64

    Abstract: During the past five decades, anticoagulant therapy has consisted of rapidly acting parenteral drugs (unfractionated heparin [UFH] low-molecular-weight heparins [LMWH]) for prevention of venous thromboembolism and initial treatment of arterial and venous ...

    Abstract During the past five decades, anticoagulant therapy has consisted of rapidly acting parenteral drugs (unfractionated heparin [UFH] low-molecular-weight heparins [LMWH]) for prevention of venous thromboembolism and initial treatment of arterial and venous thromboembolism, whereas vitamin K antagonists (VKA) are used for longer term oral treatment. These drugs act by indirectly inhibiting several activated plasma clotting factors (UFH, LMWH) or by blocking the synthesis of some of them (VKA). In recent years, compounds that specifically block activated coagulation factor X (FXa) or thrombin have been developed. Thus, fondaparinux, and its long-acting derivative idraparinux, are administered subcutaneously. These substances inhibit F Xa indirectly via antithrombin. Small molecules have also been developed that directly block FXa (rivaroxaban, apixaban) or thrombin (dabigatran etexilate) following oral administration. In the present review we discuss the currently available evidence supporting the use of these new anticoagulants, in particular rivaroxaban and dabigatran etexilate, in the setting of thromboprophylaxis following major orthopaedic surgery, and the broader perspectives that these new drugs may open up in the next few years.
    MeSH term(s) Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Arthroplasty, Replacement, Hip ; Arthroplasty, Replacement, Knee ; Benzimidazoles/therapeutic use ; Dabigatran ; Heparin/therapeutic use ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Morpholines/therapeutic use ; Orthopedic Procedures ; Postoperative Complications/prevention & control ; Pyridines/therapeutic use ; Rivaroxaban ; Thiophenes/therapeutic use ; Thromboembolism/prevention & control ; Thrombolytic Therapy/trends ; Vitamin K/antagonists & inhibitors
    Chemical Substances Anticoagulants ; Benzimidazoles ; Heparin, Low-Molecular-Weight ; Morpholines ; Pyridines ; Thiophenes ; Vitamin K (12001-79-5) ; Heparin (9005-49-6) ; Rivaroxaban (9NDF7JZ4M3) ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2008-04-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI smw-12447
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    Ua VI Zs.152: Show issues Location:
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  6. Article ; Online: Superficial thrombophlebitis of the legs: still a lot to learn. A rebuttal.

    Bounameaux, H / Righini, M / LE Gal, G

    Journal of thrombosis and haemostasis : JTH

    2018  Volume 4, Issue 1, Page(s) 289

    Language English
    Publishing date 2018-04-01
    Publishing country England
    Document type Letter
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/j.1538-7836.2005.01608.x
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  7. Article ; Online: ACP Journal Club. Ultrasonography-guided oral anticoagulant therapy reduced recurrent venous thromboembolism.

    Bounameaux, Henri

    Annals of internal medicine

    2009  Volume 151, Issue 6, Page(s) JC3–9

    Language English
    Publishing date 2009-09-15
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/0003-4819-151-6-200909150-02009
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  8. Article: More on: the early discoveries of collagen-platelet interaction and studies on its role in hemostatic plug formation.

    Bounameaux, H

    Journal of thrombosis and haemostasis : JTH

    2005  Volume 3, Issue 5, Page(s) 1116

    MeSH term(s) Animals ; Blood Coagulation ; Blood Platelets/metabolism ; Blood Platelets/ultrastructure ; Collagen/metabolism ; Hematology/history ; Hemostatics ; History, 20th Century ; Humans ; Protein Binding ; Publications ; Rabbits ; Time Factors
    Chemical Substances Hemostatics ; Collagen (9007-34-5)
    Language English
    Publishing date 2005-02-23
    Publishing country England
    Document type Comment ; Historical Article ; Letter
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/j.1538-7836.2005.01341.x
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  9. Article ; Online: Secondary Prevention of Venous Thromboembolism: One Regimen May Not Fit All.

    Blondon, Marc / Bounameaux, Henri

    Circulation

    2015  Volume 132, Issue 20, Page(s) 1856–1859

    MeSH term(s) Anticoagulants/administration & dosage ; Female ; Glycosaminoglycans/administration & dosage ; Humans ; Male ; Secondary Prevention/methods ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/prevention & control
    Chemical Substances Anticoagulants ; Glycosaminoglycans
    Language English
    Publishing date 2015-11-17
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.115.019310
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  10. Article ; Online: Catheter-directed thrombolysis for deep venous thrombosis might be cost-effective, but for whom?

    Perrier, A / Bounameaux, H

    Journal of thrombosis and haemostasis : JTH

    2013  Volume 11, Issue 6, Page(s) 1029–1031

    MeSH term(s) Catheters/economics ; Humans ; Thrombolytic Therapy/economics ; Thrombolytic Therapy/methods ; Venous Thrombosis/economics ; Venous Thrombosis/therapy
    Language English
    Publishing date 2013-04-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.12246
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