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Article ; Online: Population data and phylogenetic structure of 19 STR loci in Chinese Hui ethnic group residing in Yunnan province of China.

Zhang, Xiufeng / Yang, Yunrui / Liu, Hongping / Zuo, Wu / Huang, Lei

2022 Volume 56, Page(s) 102044

Abstract: ... in a sample of 535 unrelated healthy Hui individuals from Yunnan province were estimated. A total of 236 ... 527103. Penta E is the most informative in Hui population, whereas TPOX showed the lowest. All of the STR ... 47 16 and 0.999 999 988, respectively. Furthermore, the genetic relationship between the Yunnan Hui ...

Abstract	Allele frequency distributions and statistical forensic parameters of 19 autosomal STR loci in a sample of 535 unrelated healthy Hui individuals from Yunnan province were estimated. A total of 236 alleles at these loci were identified and their corresponding allele frequencies ranged from 0.000935 to 0.527103. Penta E is the most informative in Hui population, whereas TPOX showed the lowest. All of the STR loci reached the Hardy-Weinberg equilibrium after Bonferroni correction. The combined discrimination power and probability of excluding paternity of the 19 STR loci were 0.999 999 999 999 999 999 999 984 47 16 and 0.999 999 988, respectively. Furthermore, the genetic relationship between the Yunnan Hui population and other 8 different Hui groups or 25 previously investigated groups residing in other areas of China were also estimated based on pairwise genetic distance. These results suggest that the 19 STR loci are highly polymorphic, which is suitable for forensic personal identification and paternity testing.
MeSH term(s)	China ; DNA Fingerprinting ; Ethnicity/genetics ; Gene Frequency/genetics ; Genetics, Population ; Humans ; Microsatellite Repeats/genetics ; Phylogeny ; Polymorphism, Genetic/genetics
Language	English
Publishing date	2022-02-12
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	2019555-2
ISSN	1873-4162 ; 1344-6223
ISSN (online)	1873-4162
ISSN	1344-6223
DOI	10.1016/j.legalmed.2022.102044
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Article ; Online: The massive assimilation of indigenous East Asian populations in the origin of Muslim Hui people inferred from paternal Y chromosome.

Wang, Chuan-Chao / Lu, Yan / Kang, Longli / Ding, Huiqian / Yan, Shi / Guo, Jianxin / Zhang, Qun / Wen, Shao-Qing / Wang, Ling-Xiang / Zhang, Manfei / Tong, Xinzhu / Huang, Xiufeng / Nie, Shengjie / Deng, Qiongying / Zhu, Bofeng / Jin, Li / Li, Hui

American journal of physical anthropology

2019 Volume 169, Issue 2, Page(s) 341–347

Abstract: Objectives: The Hui people are the adherents of Muslim faith and distributing throughout China ... There are two contrasting hypotheses about the origin and diversification of the Hui people, namely ... methods: We collected 621 unrelated male individuals from 23 Hui populations all over China ...

Abstract	Objectives: The Hui people are the adherents of Muslim faith and distributing throughout China. There are two contrasting hypotheses about the origin and diversification of the Hui people, namely, the demic diffusion involving the mass movement of people or simple cultural diffusion. Materials and methods: We collected 621 unrelated male individuals from 23 Hui populations all over China. We comprehensively genotyped more than 100 informative Y-chromosomal single nucleotide polymorphisms and 17 Y-chromosomal short tandem repeats (STRs) on those samples. Results: Co-analyzed with published worldwide populations, our results suggest the origin of Hui people has involved massive assimilation of indigenous East Asians with about 70% in total of the paternal ancestry could be traced back to East Asia and the left 30% to various regions in West Eurasia. Discussion: The genetic structure of the extant Hui populations was primarily shaped by the indigenous East Asian populations as they contribute the majority part of the paternal lineages of Hui people. The West Eurasian admixture was probably a sex-biased male-driven process since we have not found such a high proportion of West Eurasian gene flow on autosomal STRs and maternal mtDNA.
MeSH term(s)	Anthropology, Physical ; Asian Continental Ancestry Group/genetics ; China ; Chromosomes, Human, Y/genetics ; Ethnic Groups/genetics ; Gene Flow/genetics ; Genetics, Population ; Humans ; Islam ; Male ; Polymorphism, Single Nucleotide/genetics
Language	English
Publishing date	2019-03-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	219376-0
ISSN	1096-8644 ; 0002-9483
ISSN (online)	1096-8644
ISSN	0002-9483
DOI	10.1002/ajpa.23823
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Article: Male-Dominated Migration and Massive Assimilation of Indigenous East Asians in the Formation of Muslim Hui People in Southwest China.

Wang, Qiyan / Zhao, Jing / Ren, Zheng / Sun, Jin / He, Guanglin / Guo, Jianxin / Zhang, Hongling / Ji, Jingyan / Liu, Yubo / Yang, Meiqing / Yang, Xiaomin / Chen, Jinwen / Zhu, Kongyang / Wang, Rui / Li, Yingxiang / Chen, Gang / Huang, Jiang / Wang, Chuan-Chao

Frontiers in genetics

2021 Volume 11, Page(s) 618614

Abstract: The origin and diversification of Muslim Hui people in China via demic or simple cultural diffusion ... single nucleotide polymorphisms (SNPs) from 45 Hui and 14 Han Chinese individuals collected from Guizhou province in southwest ...

Abstract	The origin and diversification of Muslim Hui people in China via demic or simple cultural diffusion is a long-going debate. We here generated genome-wide data at nearly 700,000 single nucleotide polymorphisms (SNPs) from 45 Hui and 14 Han Chinese individuals collected from Guizhou province in southwest China. We applied principal component analysis (PCA), ADMIXTURE,
Language	English
Publishing date	2021-01-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2020.618614
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Article ; Online: Antibiotic burden of school children from Tibetan, Hui, and Han groups in the Qinghai-Tibetan Plateau.

Huang, Yushan / Zhang, Zuhong / Hou, Tianchun / Shi, Jingfang / Huang, Wenjie / Bai, Zhao / Long, Danfeng / Huang, Xiaodan / Yan, Shijuan

PloS one

2020 Volume 15, Issue 2, Page(s) e0229205

Abstract: ... customs, we hypothesize that children from the three main ethnic populations (Han, Hui, and Tibetan ... the antibiotic residues in morning urine samples from 92 Han, 72 Tibetan, and 85 Muslim Hui primary school children aged 8 ... in the Hui children than in the Han children (P = 0.024). Dietary nutrient intake assessments were comparable ...

Abstract	Background: Given their geographical proximity but differences in cultural and religious dietary customs, we hypothesize that children from the three main ethnic populations (Han, Hui, and Tibetan) residing in the Qinghai-Tibetan Plateau region differs in their non-iatrogenic antibiotic loads. Methods: To determine the antibiotic burden of the school children unrelated to medical treatment, we quantified the antibiotic residues in morning urine samples from 92 Han, 72 Tibetan, and 85 Muslim Hui primary school children aged 8 to 12 years using high-performance liquid chromatography-tandem mass spectrometry, and performed correlation analysis between these data and concurrent dietary nutrition assessments. Results: Sixteen of the 18 targeted antibiotics (4 macrolides, 3 β-lactams, 2 tetracyclines, 4 quinolones, 3 sulfonamides, and 2 aminoanols) were identified in the urine samples with an overall detection frequency of 58.63%. The detection frequency of the six antibiotic classes ranged from 1.61% to 32.53% with ofloxacin showing the single highest frequency (18.47%). Paired comparison analysis revealed significant differences in antibiotic distribution frequency among groups, with Tibetans having higher enrofloxacin (P = 0.015) and oxytetracycline (P = 0.021) than Han children. Norfloxacin (a human/veterinary antibiotic) was significantly higher in the Hui children than in the Han children (P = 0.024). Dietary nutrient intake assessments were comparable among participants, showing adequate levels of essential vitamins and minerals across all three ethnic groups. However, significant differences in specific foods were observed among groups, notably in lower fat consumption in the Hui group. Conclusions: The introduction and accumulation of antibiotic residues in school children through non-iatrogenic routes (food or environmental sources) poses a serious potential health risk and merits closer scrutiny to determine the sources. While the exact sources of misused or overused antibiotics remains unclear, further study can potentially correlate ethnicity-specific dietary practices with the sources of contamination.
MeSH term(s)	Anti-Bacterial Agents/urine ; Child ; China/ethnology ; Chromatography, High Pressure Liquid/methods ; Diet ; Ethnic Groups ; Humans ; Nutrients/analysis ; Ofloxacin/urine ; Schools ; Tandem Mass Spectrometry/methods
Chemical Substances	Anti-Bacterial Agents ; Ofloxacin (A4P49JAZ9H)
Language	English
Publishing date	2020-02-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0229205
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Article: Oral Microbiota of Children Is Conserved across Han, Tibetan and Hui Groups and Is Correlated with Diet and Gut Microbiota.

Liu, Ke / Chen, Siyu / Huang, Jing / Ren, Feihong / Yang, Tingyu / Long, Danfeng / Li, Huan / Huang, Xiaodan

Microorganisms

2021 Volume 9, Issue 5

Abstract: ... We collected saliva from 60 school children from the Tibetan, Han and Hui ethnicities for a 16S rRNA ...

Abstract	The oral microbiota can be affected by several factors; however, little is known about the relationship between diet, ethnicity and commensal oral microbiota among school children living in close geographic proximity. In addition, the relationship between the oral and gut microbiota remains unclear. We collected saliva from 60 school children from the Tibetan, Han and Hui ethnicities for a 16S rRNA gene sequencing analysis and comparison with previously collected fecal samples. The study revealed that
Language	English
Publishing date	2021-05-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms9051030
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Article: Effect of Observation of Shou Hui Tong Bian Capsule (Polygonum Multiflorum and Aloe-Based Herbal Capsule for Cathartic Effect) in Rapid Rehabilitation of Joint Surgery.

Huang, Shu / Xie, Yong / Huang, Zhiyan / Zhang, Guimin / Chen, Guanyu / Yuan, Jun / Wang, Jing / Xiangyang, Liu / Zhou, Yizhao

publication RETRACTED

Evidence-based complementary and alternative medicine : eCAM

2021 Volume 2021, Page(s) 2268464

Abstract: Objective: To observe the effect of Shou Hui Tong Bian capsule (polygonum multiflorum and aloe ... in the observation group were orally administrated with Shou Hui Tong Bian capsule, 2 capsules/time, 3 times/day ... Conclusion: The curative effect of Shou Hui Tong Bian capsule on patients undergoing arthroscopic joint ...

Abstract	Objective: To observe the effect of Shou Hui Tong Bian capsule (polygonum multiflorum and aloe-based herbal capsule for cathartic effect) in rapid rehabilitation of joint surgery. Methods: A total of 98 patients undergoing perioperative joint surgery in our hospital from July 2019 to March 2020 were included in the study. According to the situation of arthroscopy and joint replacement therapy, the patients were randomly divided into a control group and an observation group, with 49 cases in each group. The control group was treated with conventional therapy. On the basis of the control group, the patients in the observation group were orally administrated with Shou Hui Tong Bian capsule, 2 capsules/time, 3 times/day. Both groups received continuous treatment for 14 days. The clinical effects, awakening time, postoperative exhaust time, and the number of patients with different degrees of abdominal distension in the four groups before and after treatment were observed and compared. Results: After treatment, the total effective rate of arthroscopy in the control group was 66.7%, which was significantly lower than 83.3% in the observation group ( Conclusion: The curative effect of Shou Hui Tong Bian capsule on patients undergoing arthroscopic joint surgery and joint replacement during perioperative period is obviously superior to that of conventional treatment. It can effectively improve the total effective rate, shorten the first exhaust time, and increase the number of patients without abdominal distension after treatment. It was safe and effective, and worthy of clinical promotion.
Language	English
Publishing date	2021-10-18
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2021/2268464
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Article ; Online: Impact of COVID-19 Pandemic on Pre-Treatment Delays, Detection, and Clinical Characteristics of Tuberculosis Patients in Ningxia Hui Autonomous Region, China.

Wang, Xiaolin / He, Wencong / Lei, Juan / Liu, Guangtian / Huang, Fei / Zhao, Yanlin

Frontiers in public health

2021 Volume 9, Page(s) 644536

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	COVID-19 ; China/epidemiology ; Communicable Disease Control ; Humans ; Pandemics ; SARS-CoV-2 ; Time-to-Treatment ; Tuberculosis/diagnosis
Language	English
Publishing date	2021-05-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2021.644536
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Article ; Online: Network Pharmacology-based Analysis on the Molecular Biological Mechanisms of Xin Hui Tong Formula in Coronary Heart Disease Treatment

Wu Hua-Ying / Zhang Chen / Wang Zhao-Hua / Zhang Shi-Ying / Li Jing / Li Feng / Huang Hui-Yong / Li Liang

Digital Chinese Medicine, Vol 2, Iss 2, Pp 86-

2019 Volume 96

Abstract: Objective: To investigate the potential molecular mechanism of Xin Hui Tong Formula (XHTF ... in the treatment of CHD. Keywords: Xin Hui Tong Formula (XHTF), ... ...

Abstract	Objective: To investigate the potential molecular mechanism of Xin Hui Tong Formula (XHTF) in the treatment of coronary heart disease (CHD) by using network pharmacology and bioinformatics. Methods: The targets network of CHD was constructed through Therapeutic Targets Database (TTD) and Drugbank database; The XHTF pharmacodynamic molecule-targets network and the XHTF pharmacodynamic molecule-CHD targets network were explored by the traditional Chinese medicine systems pharmacology database and analysis platform (TCMSP). And the multi-targets mechanism and molecular regulation network of XHTF in the treatment of CHD were explored from multiple perspectives by Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) database pathway enrichment analysis. Results: A total of 88 CHD targets were screened out through the Therapeutic Targets and the Drugbank database. 393 compounds and corresponding 205 drug targets of XHTF were retrieved from TCMSP. A total of 13 known targets directly related to the development of CHD were retrieved from the disease-related databases: TP53, MAPK14, NFKB1, HSPA5, PLG, PTGS2, ADRB1, NOS2, CYP3A4, GRIA2, CYP2A6, GRIA1, PTGS1. XHTF also contained 118 drug targets that directly interact with CHD targets. GO enrichment analysis showed that the biological processes of 13 direct targets proteins were found to be mainly enriched in response to drug, cellular response to biotic stimulus, long-chain fatty acid metabolic process, fatty acid metabolic process and regulation of blood pressure. KEGG pathway enrichment analysis found that XHTF participated in the CHD pathological process mainly through retrograde endocannabinoid signaling, regulation of lipolysis in adipocytes, cAMP signaling pathway, chemical carcinogenesis and other pathways. Conclusions: XHTF plays a role in the treatment of CHD through multiple targets and multiple pathways, and provides a scientific basis for the theory of “virtual standard” in the treatment of CHD. Keywords: Xin Hui Tong Formula (XHTF), ...
Keywords	Medicine ; R ; Other systems of medicine ; RZ201-999
Subject code	572
Language	English
Publishing date	2019-06-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Correction: Jiun-Nong Lin; Chung-Hsu Lai; Chih-Hui Yang and Yi-Han Huang. Comparison of Clinical Manifestations, Antimicrobial Susceptibility Patterns, and Mutations of Fluoroquinolone Target Genes between

Lin, Jiun-Nong / Lai, Chung-Hsu / Yang, Chih-Hui / Huang, Yi-Han

Journal of clinical medicine

2019 Volume 8, Issue 4

Abstract: The authors wish to make the following corrections to this paper [ ... ]. ...

Abstract	The authors wish to make the following corrections to this paper [...].
Language	English
Publishing date	2019-04-22
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm8040546
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Article ; Online: Decoupling and Decomposition Analysis of Land Natural Capital Utilization and Economic Growth: A Case Study in Ningxia Hui Autonomous Region, China.

Guo, Shanshan / Wang, Yinghong / Huang, Jiu / Dong, Jihong / Zhang, Jian

International journal of environmental research and public health

2021 Volume 18, Issue 2

Abstract: ... such studies have been relatively limited. Thus, taking the case of Ningxia Hui Autonomous Region, China ...

Abstract	In order to reduce the depletion of land natural capital and develop economy simultaneously, it is necessary to study how to achieve the strong decoupling relationship between them. However, so far such studies have been relatively limited. Thus, taking the case of Ningxia Hui Autonomous Region, China, this paper firstly analyzes the state of land natural capital utilization in 1999-2017 by using improved ecological footprint. Then, decoupling state is quantified by Tapio decoupling model. Last, major driving factors on the decoupling relationship are explored with combination of LMDI decomposition and Kaya identity equation. Results showed that: (1) Both natural capital flows and stock depletion of cultivated land decrease obviously during the transition to corn-based intensive ecological agriculture. Grassland and water are the most unsustainable development sectors among all land types with their stock depletion intensified. Forest land and construction land could basically meet the consumer demand, but the flow occupancy of construction land is the fastest-growing segment. (2) Decoupling relationship is in an alternating state between weak decoupling and strong decoupling in 1999-2017. Wherein, the cultivated land and forest land showed a preferred decoupling state, followed by grassland, while the water and construction land showed the unfavorable expansive negative decoupling and weak decoupling. (3) Decomposition results show that intensity effect is the major factor that promotes the decoupling while economic effect inhibits the decoupling, but this negative impact is weakening in the process of industrial transformation. The other three factors affect less on the decoupling. This study has a certain reference value to construct an ecological civilization in eco-fragile regions and formulate relevant policies on the increase of land natural capital efficiency.
MeSH term(s)	Agriculture ; China ; Conservation of Natural Resources ; Economic Development ; Forests ; Industry
Language	English
Publishing date	2021-01-14
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph18020646
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