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Book ; Online: Big Data Analytics and Information Science for Business and Biomedical Applications II

Ahmed, S. Ejaz / Nathoo, Farouk / Nathoo, Farouk

2022

Keywords	Information technology industries ; Computer science ; bandwidth selection ; correlation ; edge-preserving image denoising ; image sequence ; jump regression analysis ; local smoothing ; nonparametric regression ; spatio-temporal data ; linear mixed model ; ridge estimation ; pretest and shrinkage estimation ; multicollinearity ; asymptotic bias and risk ; LASSO estimation ; high-dimensional data ; big data adaptation ; dividend estimation ; options markets ; weighted least squares ; online health community ; social support ; network analysis ; cancer ; functional principal component analysis ; functional predictor ; linear mixed-effects model ; mobile device ; sparse group regularization ; wearable device data ; Bayesian modeling ; functional regression ; gestational weight ; infant birth weight ; joint modeling ; longitudinal data ; maternal weight gain ; transfer learning ; deep learning ; pretrained neural networks ; chest X-ray images ; lung diseases ; causal structure learning ; consistency ; FCI algorithm ; high dimensionality ; nonparametric testing ; PC algorithm ; fMRI ; functional connectivity ; brain network ; Human Connectome Project ; statistics
Language	English
Size	1 electronic resource (196 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030380652
ISBN	9783036555508 ; 3036555501
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Big Data Analytics and Information Science for Business and Biomedical Applications

Ahmed, S. Ejaz / Nathoo, Farouk / Nathoo, Farouk

2022

Keywords	Humanities ; Social interaction ; high-dimensional ; nonlocal prior ; strong selection consistency ; estimation consistency ; generalized linear models ; high dimensional predictors ; model selection ; stepwise regression ; deep learning ; financial time series ; causal and dilated convolutional neural networks ; nuisance ; post-selection inference ; missingness mechanism ; regularization ; asymptotic theory ; unconventional likelihood ; high dimensional time-series ; segmentation ; mixture regression ; sparse PCA ; entropy-based robust EM ; information complexity criteria ; high dimension ; multicategory classification ; DWD ; sparse group lasso ; L2-consistency ; proximal algorithm ; abdominal aortic aneurysm ; emulation ; Medicare data ; ensembling ; high-dimensional data ; Lasso ; elastic net ; penalty methods ; prediction ; random subspaces ; ant colony system ; bayesian spatial mixture model ; inverse problem ; nonparamteric boostrap ; EEG/MEG data ; feature representation ; feature fusion ; trend analysis ; text mining
Language	0\|e
Size	1 electronic resource (246 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021611585
ISBN	9783036531922 ; 3036531920
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Clinical significance of viral markers testing by ELISA and Individual Donation Nucleic Acid Testing (ID-NAT) for blood screening in blood bank: Single center study in Egypt.

Attia, Fadia M / Farouk, Ahmed M / Abdelhady, Shaymaa A

The Egyptian journal of immunology

2024 Volume 31, Issue 2, Page(s) 55–60

Abstract: Prevention of transfusion-transmitted viral infections and insurance of safe blood transfusion are the main goals of all blood banks worldwide. Despite the high sensitivity and specificity of currently used enzyme linked immunosorbent assay (ELISA) for ... ...

Abstract	Prevention of transfusion-transmitted viral infections and insurance of safe blood transfusion are the main goals of all blood banks worldwide. Despite the high sensitivity and specificity of currently used enzyme linked immunosorbent assay (ELISA) for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) testing, viral transmission could still occur during the window period. Introducing viral individual donation nucleic acid testing (ID-NAT) can greatly decrease such risk providing an additional layer in securing blood transfusion. We aimed to assess the clinical significance of viral markers testing by ELISA and ID-NAT for blood screening in the Blood Bank of Suez Canal University Hospital. We studied all donations (2132) collected during a two-months period. Blood donor samples were screened by ELISA and ID-NAT tests for HBV, HCV, and HIV. Serological testing results for HCV by ELISA revealed 2,122 (99.5 %) negative donations compared to 2,131 (99.95 %) negative donations by ID-NAT testing. Of the positive ELISA samples, only one was NAT positive. For HBV ELISA testing, 2,115 (99.2 %) donations were negative, also by ID-NAT testing 2,115 (99.2 %) donations were HBV DNA negative. Out of the negative ELISA samples, two samples were ID-NAT reactive donors which were missed by serology assay being in the window period. HIV ELISA testing revealed negative 2,130 (99.9 %) donations while ID-NAT testing showed 2,131 (99.95 %) negative donations and one positive donation. In conclusion, this is the first study carried out in the Suez Canal and Sinai region, Egypt to assess the importance of ID-NAT implementation. The introduction of ID-NAT in blood banks is an effective method for increasing safety of the blood transfusion.
MeSH term(s)	Humans ; Blood Banks ; Clinical Relevance ; Egypt ; Enzyme-Linked Immunosorbent Assay ; Hepacivirus/genetics ; Hepatitis B virus/genetics ; Hepatitis C/diagnosis ; Biomarkers ; Nucleic Acids ; HIV Infections
Chemical Substances	Biomarkers ; Nucleic Acids
Language	English
Publishing date	2024-03-22
Publishing country	Egypt
Document type	Journal Article
ISSN	1110-4902
ISSN	1110-4902
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Substantial and comparable suppression of disease activity following early initiation of cladribine tablets, ocrelizumab or alemtuzumab as first pharmacologic treatment for relapsing multiple sclerosis: A real world study.

Alroughani, Raed / Al-Hashel, Jasem / Ahmed, Samar Farouk

Clinical neurology and neurosurgery

2024 Volume 240, Page(s) 108249

Abstract: Background: We describe the efficacy and safety of recent high efficacy disease DMTs in DMT-naive patients with highly active RMS.: Methods: This was a retrospective, cross sectional study from the Kuwait national MS registry. Patients with RMS who ... ...

Abstract	Background: We describe the efficacy and safety of recent high efficacy disease DMTs in DMT-naive patients with highly active RMS. Methods: This was a retrospective, cross sectional study from the Kuwait national MS registry. Patients with RMS who received alemtuzumab, cladribine tablets or ocrelizumab as their first DMT for RMS, with ≥2 year of follow up were included. The primary endpoint was the change in relapse rate from treatment initiation to 1 year; changes in disability (Expanded Disability Status Scale [EDSS]), radiologic activity, the proportion with no evidence of disease activity-3 (NEDA-3), and the frequency of adverse events were secondary endpoints. Results: Among 123 RRMS patients, 59 received ocrelizumab, 32 received cladribine tablets and 32 received alemtuzumab. About two-thirds (65%) were women. Substantial and similar (p>0.05) reductions occurred at the end of follow-up in annual relapse rate (by 93.2% for ocrelizumab, 87.5% for cladribine tablets, and 90.6% for alemtuzumab). The proportion with new T2 of gadolinium-enhancing MRI lesions across the three groups was reduced from 85-100% to 7-13%. Rates of confirmed disability progression were low (ocrelizumab 6.9%, cladribine tablets 3.1%, alemtuzumab 0%; p=0.280); disability was reduced in 15%, 22% and 38%, respectively. NEDA-3 was observed in 89.8%, 87.5%, and 84.4, respectively (p=0.784). No new or unexpected safety issues occurred. Conclusion: Ocrelizumab, cladribine tablets and alemtuzumab reduced relapse rates and MRI activity, and prevented disease progression, when are initiated early in DMT-naive RMS patients. These data support the early use of high-efficacy DMTs for people with highly active RMS.
Language	English
Publishing date	2024-03-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	193107-6
ISSN	1872-6968 ; 0303-8467
ISSN (online)	1872-6968
ISSN	0303-8467
DOI	10.1016/j.clineuro.2024.108249
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Article: Determinants of visual and endocrinological outcome after early endoscopic endonasal surgery for pituitary apoplexy.

Galal, Ahmed / Ahmed, Omar El Farouk

Surgical neurology international

2022 Volume 13, Page(s) 433

Abstract: Background: Patients diagnosed with pituitary apoplexy and presenting with acute visual deterioration require urgent surgical resection. This is also commonly associated with pituitary hypopituitarism that requires hormonal replacement for correction. ... ...

Abstract	Background: Patients diagnosed with pituitary apoplexy and presenting with acute visual deterioration require urgent surgical resection. This is also commonly associated with pituitary hypopituitarism that requires hormonal replacement for correction. This study was undertaken to evaluate the clinical recovery of 45 patients diagnosed with symptomatic pituitary apoplexy who underwent early (within 72 h of symptom onset) endoscopic transsphenoidal surgical resection with an emphasis on visual, ocular craniopathy, and endocrinological outcome. Methods: This is a retrospective analysis of a consecutive series of patients diagnosed with pituitary apoplexy between 2011 and 2020 treated by early (within 72 h of symptom onset) endoscopic transsphenoidal surgical resection. All tumors were histologically proven as pituitary adenomas. Clinical and neuro-ophthalmological examinations, imaging studies, and endocrinological evaluation were retrospectively reviewed. Patients with a minimum of 6 months follow-up were included in the study. The influence of patients' demographics, extent of visual and ocular motility impairment, preoperative endocrinological dysfunction, tumor size and extent, degree of resection, and surgical complications were analyzed as potential prognostic factors for recovery. Results: Forty-five patients were included in this retrospective study. Ages ranged from 27 to 57 years (mean: 42 years). All patients presented with headache and variable degrees of visual loss and visual field deficit. Ophthalmoplegia was present in 22 (48.9%) patients with 17 (37.8%) having bilateral ocular cranial nerve palsy. All patients had variable degrees of endocrinological deficiencies. All patients showed evidence of low cortisol, 14 (31.1%) showed hypothyroidism and 11 (24.4%) showed hypogonadism. There was evidence of hyperprolactinemia in 16 (35.6%) patients. All patients harbored a pituitary macroadenoma. Tumor resection was complete in 33 (73%) of patients, with residual tumor related to cavernous sinus or retrosellar extension. Operative complications were mainly related to short-term nasal complications occurring in 14 (31%) patients. Cerebrospinal fluid leak requiring revision surgery occurred in only one patient harboring a modified SIPAP Grade 3s tumor. Transient diabetes insipidus occurred in 9 (20%) patients, with 2 (4.4%) requiring long-term hormonal replacement. The mean follow-up was 25 months. Baseline visual improvement was achieved in 39 (86.7%) patients. Ocular cranial nerve palsy showed complete recovery in 17 (77.2%) patients. Endocrine follow-up showed that patients with panhypopituitarism (11 [24.4%]) failed to recover. Conclusion: The current surgical series showed safety in terms of low complication rate and efficacy in terms of clinical outcome. The significant prognostic factor related to visual recovery was the degree of preoperative visual deficit. Recovery of ocular cranial neuropathy showed a higher recovery rate when it was unilateral as opposed to bilateral. Pituitary hormonal recovery was less favorable with pituitary panhypopituitarism being a poor prognostic factor.
Language	English
Publishing date	2022-09-23
Publishing country	United States
Document type	Journal Article
ISSN	2229-5097
ISSN	2229-5097
DOI	10.25259/SNI_642_2022
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Efficient quantum algorithms for set operations.

Elgendy, Rehab / Younes, Ahmed / Abu-Donia, H M / Farouk, R M

Scientific reports

2024 Volume 14, Issue 1, Page(s) 7015

Abstract: Analyzing the relations between Boolean functions has many applications in many fields, such as database systems, cryptography, and collision problems. This paper proposes four quantum algorithms that use amplitude amplification techniques to perform set ...

Abstract	Analyzing the relations between Boolean functions has many applications in many fields, such as database systems, cryptography, and collision problems. This paper proposes four quantum algorithms that use amplitude amplification techniques to perform set operations, including Intersection, Difference, and Union, on two Boolean functions in
Language	English
Publishing date	2024-03-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-56860-2
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Article ; Online: Surgical Approaches for Managing Femoral Head Fractures (FHFs); What and How to Choose from the Different Options?

Khalifa, Ahmed A / Ahmed, Esraa M / Farouk, Osama A

Orthopedic research and reviews

2022 Volume 14, Page(s) 133–145

Abstract: Femoral head fractures (FHFs) are considered a relatively uncommon injury; however, they carry a challenge to the trauma surgeon. Choosing the appropriate management option, either conservatively or surgically, if the latter was chosen, should it be open ...

Abstract	Femoral head fractures (FHFs) are considered a relatively uncommon injury; however, they carry a challenge to the trauma surgeon. Choosing the appropriate management option, either conservatively or surgically, if the latter was chosen, should it be open reduction and internal fixation or simple excision of the fragment, or acute total hip arthroplasty. Furthermore, selecting the best surgical approach through which surgical management could be performed depends on the fracture classification, the familiarity of the surgeon, and the presence of associated injuries. All approaches to the hip, including hip arthroscopy, had been proposed for the management of FHFs; however, the difference among approaches is related to the complexity of the approach, the need for special training or equipment, the effect of the approach on the functional outcomes as well as the rate of postoperative complications. This review discussed the possible surgical approaches used to manage FHFs, advantages, and disadvantages for each, and offered a guideline for selecting the most appropriate surgical approach.
Language	English
Publishing date	2022-04-23
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2520718-0
ISSN	1179-1462 ; 1179-1462
ISSN (online)	1179-1462
ISSN	1179-1462
DOI	10.2147/ORR.S353582
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical and Radiographic Predictors of Successful Coronary Angiography Through Right Radial Artery Access.

Elfar, Sohil / Onsy, Ahmed / Farouk, Mohamed Amr

Interventional cardiology (London, England)

2023 Volume 18, Page(s) e21

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2813989-6
ISSN	1756-1485 ; 1756-1485
ISSN (online)	1756-1485
ISSN	1756-1485
DOI	10.15420/icr.2023.04
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Bladder cancer: therapeutic challenges and role of 3D cell culture systems in the screening of novel cancer therapeutics.

Farouk, Sameh M / Khafaga, Asmaa F / Abdellatif, Ahmed M

Cancer cell international

2023 Volume 23, Issue 1, Page(s) 251

Abstract: Bladder cancer (BC) is the sixth most common worldwide urologic malignancy associated with elevated morbidity and mortality rates if not well treated. The muscle-invasive form of BC develops in about 25% of patients. Moreover, according to estimates, 50% ...

Abstract	Bladder cancer (BC) is the sixth most common worldwide urologic malignancy associated with elevated morbidity and mortality rates if not well treated. The muscle-invasive form of BC develops in about 25% of patients. Moreover, according to estimates, 50% of patients with invasive BC experience fatal metastatic relapses. Currently, resistance to drug-based therapy is the major tumble to BC treatment. The three-dimensional (3D) cell cultures are clearly more relevant not only as a novel evolving gadget in drug screening but also as a bearable therapeutic for different diseases. In this review, various subtypes of BC and mechanisms of drug resistance to the commonly used anticancer therapies are discussed. We also summarize the key lineaments of the latest cell-based assays utilizing 3D cell culture systems and their impact on understanding the pathophysiology of BC. Such knowledge could ultimately help to address the most efficient BC treatment.
Language	English
Publishing date	2023-10-25
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2091573-1
ISSN	1475-2867
ISSN	1475-2867
DOI	10.1186/s12935-023-03069-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Value of different CTO scoring systems in predicting procedural success in coronary chronic total occlusion intervention in Egyptian patients.

AlAshry, Ahmed Mohammed Ali / Nagiub, Muhammed Nagy / Ismael, Magdy Farouk Ahmed / Alghonaimy, Wesam

The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

2024 Volume 76, Issue 1, Page(s) 30

Abstract: Background: Chronic total occlusion (CTO) lesions in coronary arteries pose a significant challenge for coronary interventionists, often leading to referrals for coronary artery bypass graft surgery (CABG). Successful percutaneous coronary intervention ( ...

Abstract	Background: Chronic total occlusion (CTO) lesions in coronary arteries pose a significant challenge for coronary interventionists, often leading to referrals for coronary artery bypass graft surgery (CABG). Successful percutaneous coronary intervention (PCI) for CTOs requires accurate assessment of procedural potential. This study, comprising 100 Egyptian patients aged 37-81, compares the predictive efficacy of various CTO scoring systems in PCI success determination. Patients with CTO in at least one coronary artery, planned for elective PCI based on objective evidence of ischemia, were included. Experienced operators performed PCI, recording procedural variables, and assessing complications. Logistic regression analysis revealed an inverse linear relationship between success rates and score values across all systems. Results: Although, the predictive capacity of the scores was similar, with slight differences. The Euro CTO (CASTLE) score Conclusion: The CASTLE score
Language	English
Publishing date	2024-03-05
Publishing country	Germany
Document type	Journal Article
ISSN	2090-911X
ISSN (online)	2090-911X
DOI	10.1186/s43044-024-00458-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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