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  1. Article ; Online: Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice.

    Yun, Ye-Rang / Lee, Ji-Eun

    Nutrition research (New York, N.Y.)

    2024  Volume 124, Page(s) 43–54

    Abstract: Kimchi is a traditional fermented food that contains abundant nutrients and functional ingredients with various health benefits. We previously reported that kimchi active components suppress hepatic steatosis caused by endoplasmic reticulum (ER) stress ... ...

    Abstract Kimchi is a traditional fermented food that contains abundant nutrients and functional ingredients with various health benefits. We previously reported that kimchi active components suppress hepatic steatosis caused by endoplasmic reticulum (ER) stress in vitro and in vivo. Therefore, we assessed the effect of kimchi on the inhibition of hepatic steatosis caused by ER stress in HepG2 cells and C57BL/6N mice to verify the hypothesis that kimchi may potentially inhibit nonalcoholic fatty liver disease. We investigated the effect of kimchi on cell viability and triglyceride concentrations in cells and on lipid profile, lipid accumulation, and expression of related genes in cells and mice with hepatic steatosis. A mechanistic study was also performed using the liver X receptor α agonist T0901317 and the AMP-activated protein kinase agonist AICAR. Kimchi was noncytotoxic and effectively reduced triglyceride concentrations and suppressed hepatic steatosis-related gene expression in cells and mice. Additionally, kimchi recovered weight loss, lowered the serum and liver tissue lipid profiles, suppressed lipid accumulation, and reduced the effects of T0901317 and AICAR on lipogenic gene expression in tunicamycin-treated mice. Our results highlight that kimchi could prevent hepatic steatosis caused by ER stress in cells and mice.
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2024.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Multiple grouped vesicles on the face in a patient with multiple myeloma.

    Doh, Jee Yun / Lee, Ji Hyun

    JAAD case reports

    2023  Volume 34, Page(s) 97–100

    Language English
    Publishing date 2023-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.02.014
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  3. Article ; Online: Prediction of complete response after neoadjuvant chemotherapy for invasive breast cancers: The utility of shear wave elastography and superb microvascular imaging in pretreatment breast ultrasound.

    Lee, Eun Ji / Chang, Yun-Woo

    European journal of radiology

    2024  Volume 175, Page(s) 111432

    Abstract: Purpose: To investigate whether multiparametric parameters of pretreatment breast ultrasound (US) and clinicopathologic factors are associated with pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer.: Methods: ... ...

    Abstract Purpose: To investigate whether multiparametric parameters of pretreatment breast ultrasound (US) and clinicopathologic factors are associated with pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer.
    Methods: Between November 2018 and September 2022, 88 patients who underwent NAC and subsequent surgery were included in this study (median age, 55 years; interquartile range [IQR], 45, 59.3). Multiparametric breast US including grayscale, shear wave elastography (SWE) and superb microvascular imaging (SMI) of pathologically proven invasive breast cancers were retrospectively reviewed. Clinicopathological and multiparametric parameters of breast US, including size, SWEmax, SWEratio and vascular index on SMI (SMI
    Results: The pCR group (n = 24) showed a significantly smaller tumor size, lower SWEmax, higher Ki-67 index, higher hormone receptor negativity and negative axillary lymph node metastasis compared to the non-pCR group (n = 64). Multivariate regression analysis showed that SWEmax (adjusted odds ratio[aOR] = 0.956, 95 % confidence interval [CI] = 0.919-0.994, P = 0.025) and Ki-67 index (aOR = 1.083, 95 % CI = 1.012-1.159, P = 0.021) were independently associated with pathologically complete response. The optimal cut-off values for predicting pCR were 27.5 % for Ki-67 with an AUC of 0.743 and 134.8 kPa for SWEmax with an AUC of 0.779. A combination model including clinical factors and SWEmax showed the best diagnostic performance with an AUC of 0.876.
    Conclusion: A higher Ki-67 index and lower SWEmax measured on pretreatment breast US were independently associated with pCR in invasive breast cancer after NAC.
    Language English
    Publishing date 2024-03-21
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2024.111432
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    Zs.A 1630: Show issues Location:
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  4. Article ; Online: A Comparison of Health Risks from PM

    Jeon, Jeong-In / Jung, Ji-Yun / Park, Shin-Young / Lee, Hye-Won / Lee, Jeong-Il / Lee, Cheol-Min

    Toxics

    2024  Volume 12, Issue 2

    Abstract: Particulate matter (PM) can cause illness, including respiratory diseases, and ... ...

    Abstract Particulate matter (PM) can cause illness, including respiratory diseases, and PM
    Language English
    Publishing date 2024-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics12020158
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  5. Article: Ethyl acetate fraction of oregano seed protects non-alcoholic fatty liver in high-fat diet-induced obese mice through modulation of

    Lee, Hyun-Jong / Bae, Ji-Yun / Park, Kye Won / Kim, Mi-Ja

    Food science & nutrition

    2024  Volume 12, Issue 4, Page(s) 2578–2587

    Abstract: Oregano ( ...

    Abstract Oregano (
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.3939
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  6. Article ; Online: Attention-guided jaw bone lesion diagnosis in panoramic radiography using minimal labeling effort.

    Gwak, Minseon / Yun, Jong Pil / Lee, Ji Yun / Han, Sang-Sun / Park, PooGyeon / Lee, Chena

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4981

    Abstract: Developing a deep-learning-based diagnostic model demands extensive labor for medical image labeling. Attempts to reduce the labor often lead to incomplete or inaccurate labeling, limiting the diagnostic performance of models. This paper (i) constructs ... ...

    Abstract Developing a deep-learning-based diagnostic model demands extensive labor for medical image labeling. Attempts to reduce the labor often lead to incomplete or inaccurate labeling, limiting the diagnostic performance of models. This paper (i) constructs an attention-guiding framework that enhances the diagnostic performance of jaw bone pathology by utilizing attention information with partially labeled data; (ii) introduces an additional loss to minimize the discrepancy between network attention and its label; (iii) introduces a trapezoid augmentation method to maximize the utility of minimally labeled data. The dataset includes 716 panoramic radiograph data for jaw bone lesions and normal cases collected and labeled by two radiologists from January 2019 to February 2021. Experiments show that guiding network attention with even 5% of attention-labeled data can enhance the diagnostic accuracy for pathology from 92.41 to 96.57%. Furthermore, ablation studies reveal that the proposed augmentation methods outperform prior preprocessing and augmentation combinations, achieving an accuracy of 99.17%. The results affirm the capability of the proposed framework in fine-grained diagnosis using minimally labeled data, offering a practical solution to the challenges of medical image analysis.
    MeSH term(s) Humans ; Radiography, Panoramic ; Bone Diseases ; Radiologists
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55677-3
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  7. Article: Anti-Inflammatory Effects of

    Lee, Ji Yun / Kim, Ji-Hyun / Choi, Ji Myung / Noh, Byeong Wook / Kim, Hyun Young / Cho, Eun Ju

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 7

    Abstract: Ulcerative colitis is a chronic inflammatory disease caused by abnormal immune responses in the intestinal mucosa and gut microorganisms. Unlike other mugworts, ...

    Abstract Ulcerative colitis is a chronic inflammatory disease caused by abnormal immune responses in the intestinal mucosa and gut microorganisms. Unlike other mugworts,
    Language English
    Publishing date 2024-03-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13070998
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  8. Article ; Online: Rational design of conductive metal-organic frameworks and aligned carbon nanofibers for enhancing the performance of flexible supercapacitors.

    Kim, Dongyeon / Yun, Tae Gwang / Lee, Ji Hyun / Yoon, Ki Ro / Kim, Kyunghoon

    Nanoscale advances

    2024  Volume 6, Issue 7, Page(s) 1900–1908

    Abstract: Carbonaceous materials are attractive active materials for the manufacture of flexible electrochemical double-layer capacitors (EDLCs) because of their high electrical conductivity, large surface area, and inherent resilience against deformation. However, ...

    Abstract Carbonaceous materials are attractive active materials for the manufacture of flexible electrochemical double-layer capacitors (EDLCs) because of their high electrical conductivity, large surface area, and inherent resilience against deformation. However, compared to pseudocapacitors, which store electrochemical energy
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d3na00695f
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  9. Article: Validation of the Korean Version of Culturally Responsive Experiences in Close Relationships-Short Form.

    Lee, Ji-Yeon / Kim, Yun-Kyung / Shin, Yun-Jeong

    International journal for the advancement of counseling

    2023  Volume 45, Issue 1, Page(s) 57–81

    Abstract: The authors developed and validated the Korean version of the Experiences in Close Relationships-Short Form (K-ECRR-SF) with the goal of developing a culturally responsive scale. In study 1, a Rasch analysis was conducted on the 36 original items in the ... ...

    Abstract The authors developed and validated the Korean version of the Experiences in Close Relationships-Short Form (K-ECRR-SF) with the goal of developing a culturally responsive scale. In study 1, a Rasch analysis was conducted on the 36 original items in the ECR-Revised (ECR-R) to select items that best represent anxiety and avoidance subscales by considering cultural equivalence. In study 2, confirmatory factor analysis (CFA) was conducted for the selected 12 items with a different sample. The factor structures of the ECR-R and K-ECRR-SF through CFA were then compared through CFA. In addition, the K-ECRR-SF items were tested for related constructs (i.e., reassurance and support seeking, loneliness, dyadic satisfaction, depression, anxiety, and fear of intimacy) to its criterion evidence. The newly developed K-ECRR-SF is confirmed to be valid and culturally responsive scale in measuring attachment in Korea.
    Language English
    Publishing date 2023-02-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2015741-1
    ISSN 1573-3246 ; 0165-0653
    ISSN (online) 1573-3246
    ISSN 0165-0653
    DOI 10.1007/s10447-023-09503-6
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  10. Article ; Online: Metal-free electrocatalytic nanocomposites of poly azovan blue-decorated graphitic carbon nitride for simultaneously sensing paracetamol and 4-aminophenol.

    Sekar, Sankar / Yun, Ji-Seop / Lee, Sejoon

    Environmental research

    2023  Volume 239, Issue Pt 1, Page(s) 117293

    Abstract: Excessive consumption of paracetamol (PA) and 4-aminophenol (4-AP) can have harmful effects on the human body. This study developed a novel electroanalytical technique that utilizes the nanocomposites of poly azovan blue (PAB)-decorated graphitic carbon ... ...

    Abstract Excessive consumption of paracetamol (PA) and 4-aminophenol (4-AP) can have harmful effects on the human body. This study developed a novel electroanalytical technique that utilizes the nanocomposites of poly azovan blue (PAB)-decorated graphitic carbon nitride (g-C
    MeSH term(s) Humans ; Acetaminophen ; Evans Blue ; Reproducibility of Results ; Nanocomposites/chemistry ; Carbon/chemistry ; Metals
    Chemical Substances graphitic carbon nitride ; 4-aminophenol (R7P8FRP05V) ; Acetaminophen (362O9ITL9D) ; Evans Blue (45PG892GO1) ; Carbon (7440-44-0) ; Metals
    Language English
    Publishing date 2023-10-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.117293
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