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  1. Article ; Online: Laryngeal mask airway training on the Advanced Life Support (ALS) Course--is it enough?

    Hulatt, Laurence James

    Resuscitation

    2010  Volume 81, Issue 8, Page(s) 1045

    MeSH term(s) Cardiopulmonary Resuscitation/education ; Cardiopulmonary Resuscitation/instrumentation ; Education, Nonprofessional/methods ; Humans ; Laryngeal Masks ; Manikins
    Language English
    Publishing date 2010-08
    Publishing country Ireland
    Document type Letter
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2010.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1048: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Interventions for reducing anticholinergic medication burden in older adults-a systematic review and meta-analysis.

    Braithwaite, Eve / Todd, Oliver M / Atkin, Abigail / Hulatt, Rachel / Tadrous, Ragy / Alldred, David P / Pirmohamed, Munir / Walker, Lauren / Lawton, Rebecca / Clegg, Andrew

    Age and ageing

    2023  Volume 52, Issue 9

    Abstract: Introduction: Anticholinergic medications block the neurotransmitter acetylcholine in the brain and peripheral nervous system. Many medications have anticholinergic properties, and the cumulative effect of these medications is termed anticholinergic ... ...

    Abstract Introduction: Anticholinergic medications block the neurotransmitter acetylcholine in the brain and peripheral nervous system. Many medications have anticholinergic properties, and the cumulative effect of these medications is termed anticholinergic burden. Increased anticholinergic burden can have short-term side effects such as dry mouth, blurred vision and urinary retention as well as long-term effects including dementia, worsening physical function and falls.
    Methods: We carried out a systematic review (SR) with meta-analysis (MA) looking at randomised controlled trials addressing interventions to reduce anticholinergic burden in older adults.
    Results: We identified seven papers suitable for inclusion in our SR and MA. Interventions included multi-disciplinary involvement in medication reviews and deprescribing of AC medications. Pooled data revealed no significant difference in outcomes between control and intervention group for falls (OR = 0.76, 95% CI: 0.52-1.11, n = 647), cognition (mean difference = 1.54, 95% CI: -0.04 to 3.13, n = 405), anticholinergic burden (mean difference = 0.04, 95% CI: -0.11 to 0.18, n = 710) or quality of life (mean difference = 0.04, 95% CI: -0.04 to 0.12, n = 461).
    Discussion: Overall, there was no significant difference with interventions to reduce anticholinergic burden. As we did not see a significant change in anticholinergic burden scores following interventions, it is likely other outcomes would not change. Short follow-up time and lack of training and support surrounding successful deprescribing may have contributed.
    MeSH term(s) Humans ; Aged ; Quality of Life ; Cholinergic Antagonists/adverse effects ; Acetylcholine ; Brain ; Cognition
    Chemical Substances Cholinergic Antagonists ; Acetylcholine (N9YNS0M02X)
    Language English
    Publishing date 2023-09-21
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 186788-x
    ISSN 1468-2834 ; 0002-0729
    ISSN (online) 1468-2834
    ISSN 0002-0729
    DOI 10.1093/ageing/afad176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 448: Show issues

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  3. Article: Darier's disease: hopes and challenges.

    Hulatt, Laurence / Burge, Susan

    Journal of the Royal Society of Medicine

    2003  Volume 96, Issue 9, Page(s) 439–441

    MeSH term(s) Darier Disease/drug therapy ; Darier Disease/genetics ; Darier Disease/pathology ; Genetic Counseling/ethics ; Genetic Counseling/methods ; Genetic Engineering/ethics ; Humans ; Male ; Prenatal Diagnosis/ethics ; Prenatal Diagnosis/methods ; Severity of Illness Index
    Language English
    Publishing date 2003-09-03
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 6731-3
    ISSN 1758-1095 ; 0141-0768 ; 0035-9157
    ISSN (online) 1758-1095
    ISSN 0141-0768 ; 0035-9157
    DOI 10.1177/014107680309600906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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