Result 1 - 10 of total 10
InFo Hämatol Onkol
| Keywords | covid19 |
|---|---|
| Publisher | PMC |
| Document type | Article ; Online |
| DOI | 10.1007/s15004-020-8291-1 |
| Database | COVID19 |
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1986
| Size | 1 Mikrofiche : 24x |
|---|---|
| Document type | Book ; Thesis |
| Thesis / German Habilitation thesis | Frankfurt (Main), Univ., Diss., 1986 |
| Note | Manuskript: 67 Bl. : graph. Darst. |
| HBZ-ID | HT003054410 |
| Database | Catalogue ZB MED Medicine, Health |
| Shelf mark | Loan status | Location |
|---|---|---|
| 1988 MB 344 | order for loan | Magazin |
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2010 , Page(s) 10hta07
| Event/congress | 10. Symposium Health Technology Assessment; Köln; Deutsche Agentur für Health Technology Assessment des Deutschen Instituts für Medizinische Dokumentation und Information; 2010 |
|---|---|
| Keywords | Medizin, Gesundheit |
| Publishing date | 2010-03-16 |
| Publisher | German Medical Science GMS Publishing House; Düsseldorf |
| Document type | Conference proceedings |
| DOI | 10.3205/10hta07 |
| Database | German Medical Science |
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2016 Volume 36, Page(s) 407–411
Abstract: Background: Hospital-acquired infections (HAI) still pose a major problem in inpatient care. The single most important measure for preventing HAIs is to improve adherence to hand hygiene among health care professionals.: Objective: To assess the ... ...
| Abstract | Background: Hospital-acquired infections (HAI) still pose a major problem in inpatient care. The single most important measure for preventing HAIs is to improve adherence to hand hygiene among health care professionals. Objective: To assess the feasibility of an innovative hands-on training to improve adherence to hygiene rules under standardized and under real life conditions. Design: Before-after controlled cohort trial to assess the feasibility of implementing an innovative hands-on training to improve hand hygiene adherence. Setting: Large university hospital in Germany. Participants: Fifty trained nurses from three wards with an average age of 32years (±10.22years) and an average vocational experience of 6.85years (±7.54years). Methods: The intervention consisted of a hands-on training in the skills lab of the University of Cologne complemented by a 12-week observation period before and after the training on participating wards. The training comprised important skills with respect to hand hygiene, venipuncture, dressing changes of central venous catheters, preparation of IV infusions, and donning of gloves using sterile technique. A communication training was included to enable nurses to enforce hygiene rules in their collaboration with peers and physicians. The intervention was taught in small groups with a wide array of interactive teaching methods. It was evaluated using the objective structured clinical examination (OSCE) format. Observations were conducted by a trained infection control nurse. Results: Before (after) the intervention 622 (612) occasions of hand hygiene were documented. A highly significant improvement in hygiene compliance was observed pre- and post-intervention (64.3% vs. 79.2%; p≤0.0001). The OSCE evaluation showed significant improvements in all subscales. Conclusion: The developed and conducted hands-on training seems feasible and is successful in significantly improving adherence to hygiene rules under standardized and real life conditions. Whether the effect is stable over time is subject to further investigation. |
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| MeSH term(s) | Adult ; Cohort Studies ; Feasibility Studies ; Germany ; Guideline Adherence ; Hand Hygiene/standards ; Hospitals, University ; Humans ; Program Evaluation ; Young Adult |
| Language | English |
| Publishing date | 2016-01 |
| Publishing country | Scotland |
| Document type | Comparative Study ; Journal Article |
| ZDB-ID | 1062570-7 |
| ISSN | 1532-2793 ; 0260-6917 |
| ISSN (online) | 1532-2793 |
| ISSN | 0260-6917 |
| DOI | 10.1016/j.nedt.2015.10.012 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 3117: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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1986
| Author's details | Hans-Martin Wenchel |
|---|---|
| Language | German |
| Size | 1 Mikrofiche, 24x |
| Document type | Book ; Thesis |
| Thesis / German Habilitation thesis | @Frankfurt (Main), Univ., Diss. : 1986 |
| Note | Mikroreprod. e. Ms. 67 Bl. : graph. Darst |
| Database | Former special subject collection: coastal and deep sea fishing |
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2013 Volume 27, Issue 1, Page(s) 84–90
Abstract: Background: For palliative care settings, little is known about the benefits of specific methicillin-resistant Staphylococcus aureus containment regimens and the burdens patient isolation imposes on affected patients, their families, and professional ... ...
| Abstract | Background: For palliative care settings, little is known about the benefits of specific methicillin-resistant Staphylococcus aureus containment regimens and the burdens patient isolation imposes on affected patients, their families, and professional caregivers. Aim: To explore the current practice of MRSA management and its impact on inpatients' quality of life as perceived by professional caregivers. Design: Survey of inpatient palliative care institutions using 23-item questionnaires (infrastructural data: six items, management process: 14, clinical significance: three). Setting/participants: All palliative care units (179) and hospices (181) listed in Germany's directory of palliative care services. The χ(2) test was used to test for differences; significance level: p ≤ 0.05. Results: 229 of 360 questionnaires were returned. More than 90% of the responding institutions employed specific MRSA protocols. Lack of resources was a more important issue for palliative care units than for hospices regarding availability of single rooms (p = 0.002) and staffing (p = 0.004). Compared to hospices, palliative care units more frequently isolated MRSA patients (p = 0.000), actively treated colonization (p = 0.026), assessed the efficacy of eradication (p = 0.000), provided information on MRSA management to patients (p = 0.014) and relatives (p = 0.001), more often restricted patients' activities (p = 0.000), and reported a negative impact on quality of life (p = 0.000). Conclusions: Rigorously applied MRSA protocols impose significant burdens at the end of life. Research on clinical outcomes including quality of life may identify interventions of questionable benefit. The issue of handling MRSA should be studied as a model for the management of other highly complex conditions and special needs such as patient isolation. |
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| MeSH term(s) | Attitude of Health Personnel ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Disease Management ; Germany ; Hospices/methods ; Hospices/standards ; Humans ; Infection Control/methods ; Methicillin-Resistant Staphylococcus aureus ; Palliative Care/methods ; Palliative Care/standards ; Patient Isolation/utilization ; Quality of Life ; Staphylococcal Infections/prevention & control ; Surveys and Questionnaires |
| Language | English |
| Publishing date | 2013-01 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 639247-7 |
| ISSN | 1477-030X ; 0269-2163 |
| ISSN (online) | 1477-030X |
| ISSN | 0269-2163 |
| DOI | 10.1177/0269216311425709 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2285: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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BMC infectious diseases
2008 Volume 8, Page(s) 70
Abstract: Background: Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic.: Methods: Prospective multicenter surveillance for HAI and ... ...
| Abstract | Background: Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic. Methods: Prospective multicenter surveillance for HAI and nosocomial fever of unknown origin (nFUO) with specific case definitions and standardized surveillance methods. Results: 7 pediatric oncology centers (university facilities) participated from April 01, 2001 to August 31, 2005. During 54,824 days of inpatient surveillance, 727 HAIs and nFUOs were registered in 411 patients. Of these, 263 (36%) were HAIs in 181 patients, for an incidence density (ID) (number of events per 1,000 inpatient days) of 4.8 (95% CI 4.2 to 5.4; range 2.4 to 11.7; P < 0.001), and 464 (64%) were nFUO in 230 patients. Neutropenia at diagnosis correlated significantly with clinical severity of HAI. Of the 263 HAIs, 153 (58%) were bloodstream infections (BSI). Of the 138 laboratory-confirmed BSIs, 123 (89%) were associated with use of a long-term central venous catheter (CVAD), resulting in an overall ID of 2.8 per 1,000 utilization days (95% CI 2.3 to 3.3). The ID was significantly lower in Port-type than in Hickman-type CVADs. The death of 8 children was related to HAI, including six cases of aspergillosis. The attributable mortality was 3.0% without a significant association to neutropenia at time of NI diagnosis. Conclusion: Our study confirmed that pediatric cancer patients are at an increased risk for specific HAIs. The prospective surveillance of HAI and comparison with cumulative multicenter results are indispensable for targeted prevention of these adverse events of anticancer treatment. |
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| MeSH term(s) | Adolescent ; Bacteremia/epidemiology ; Bacteremia/microbiology ; Bacteremia/mortality ; Catheterization, Central Venous/adverse effects ; Catheterization, Central Venous/statistics & numerical data ; Child ; Child, Preschool ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Cross Infection/mortality ; Fever of Unknown Origin/epidemiology ; Fever of Unknown Origin/microbiology ; Fever of Unknown Origin/mortality ; Germany/epidemiology ; Hospitals, University ; Humans ; Incidence ; Infant ; Infections/epidemiology ; Infections/microbiology ; Infections/mortality ; Neoplasms/complications ; Neutropenia/complications ; Population Surveillance/methods ; Risk Factors ; Severity of Illness Index ; Switzerland/epidemiology |
| Language | English |
| Publishing date | 2008-05-23 |
| Publishing country | England |
| Document type | Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't |
| ISSN | 1471-2334 |
| ISSN (online) | 1471-2334 |
| DOI | 10.1186/1471-2334-8-70 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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BMC Infectious Diseases, Vol 8, Iss 1, p
results of a prospective surveillance study from university hospitals in Germany and Switzerland
2008 Volume 70
Abstract: Abstract Background Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic. Methods Prospective multicenter surveillance for HAI and ... ...
| Abstract | Abstract Background Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic. Methods Prospective multicenter surveillance for HAI and nosocomial fever of unknown origin (nFUO) with specific case definitions and standardized surveillance methods. Results 7 pediatric oncology centers (university facilities) participated from April 01, 2001 to August 31, 2005. During 54,824 days of inpatient surveillance, 727 HAIs and nFUOs were registered in 411 patients. Of these, 263 (36%) were HAIs in 181 patients, for an incidence density (ID) (number of events per 1,000 inpatient days) of 4.8 (95% CI 4.2 to 5.4; range 2.4 to 11.7; P < 0.001), and 464 (64%) were nFUO in 230 patients. Neutropenia at diagnosis correlated significantly with clinical severity of HAI. Of the 263 HAIs, 153 (58%) were bloodstream infections (BSI). Of the 138 laboratory-confirmed BSIs, 123 (89%) were associated with use of a long-term central venous catheter (CVAD), resulting in an overall ID of 2.8 per 1,000 utilization days (95% CI 2.3 to 3.3). The ID was significantly lower in Port-type than in Hickman-type CVADs. The death of 8 children was related to HAI, including six cases of aspergillosis. The attributable mortality was 3.0% without a significant association to neutropenia at time of NI diagnosis. Conclusion Our study confirmed that pediatric cancer patients are at an increased risk for specific HAIs. The prospective surveillance of HAI and comparison with cumulative multicenter results are indispensable for targeted prevention of these adverse events of anticancer treatment. |
|---|---|
| Keywords | Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Infectious and parasitic diseases ; RC109-216 |
| Subject code | 610 |
| Language | English |
| Publishing date | 2008-05-01T00:00:00Z |
| Publisher | BioMed Central |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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2001 Volume 97, Issue 2, Page(s) 409–411
Abstract: Unlabelled: We investigated the effect of ropivacaine combined with sufentanil, a mixture frequently used for postoperative epidural analgesia, on the growth of Staphylococcus aureus and Pseudomonas aeruginosa at room temperature. Aliquots of suspension ...
| Abstract | Unlabelled: We investigated the effect of ropivacaine combined with sufentanil, a mixture frequently used for postoperative epidural analgesia, on the growth of Staphylococcus aureus and Pseudomonas aeruginosa at room temperature. Aliquots of suspension of S. aureus and P. aeruginosa in saline were transferred into test tubes containing either a mixture of ropivacaine 0.1% and sufentanil 1 microg/mL (R+S) or saline (SA), with the latter serving as control. At 0, 3, 6, 24, and 48 h after inoculation, 1 mL of each solution was spread over standard blood agar. The plates were incubated at 22 degrees C for 48 h, and the numbers of colony-forming units (cfu) were counted. The growth ratio for both bacterial strains was calculated as cfu time (t(n))/cfu baseline (t(0)). The primary efficacy variable was the area under the curve (AUC) in (cfu t(n)/cfu t(0)) x time, based on the growth ratios. The AUC for P. aeruginosa was significantly less in R+S than in SA (P = 0.028). Multiplication of P. aeruginosa (growth ratio >1) was observed for at least 6 h after inoculation in SA. Growth of P. aeruginosa was significantly less in R+S than in SA at 3 h (P = 0.043) and 24 h (P = 0.012) after inoculation. The AUC for S. aureus did not differ significantly between R+S and SA (P = 0.74). Neither R+S nor SA promoted multiplication of S. aureus. Forty-eight hours after inoculation, growth of S. aureus was significantly less in R+S than in SA (P < 0.0001). We conclude that R+S inhibited growth of P. aeruginosa and did not promote multiplication of S. aureus when compared with SA. Implications: This laboratory study demonstrated that compared with saline, ropivacaine 0.1% with 1 microg/mL of sufentanil inhibited growth of Pseudomonas aeruginosa and did not promote multiplication of Staphylococcus aureus at room temperature. With respect to bacterial infection with these two strains, the mixture seems to be safe for continuous epidural administration if prepared under aseptic conditions and after alcohol hand rub. |
|---|---|
| MeSH term(s) | Amides/pharmacology ; Analgesia, Epidural ; Analgesics, Opioid/pharmacology ; Anesthetics, Combined/pharmacology ; Anesthetics, Local/pharmacology ; Area Under Curve ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/growth & development ; Ropivacaine ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development ; Sufentanil/pharmacology |
| Chemical Substances | Amides ; Analgesics, Opioid ; Anesthetics, Combined ; Anesthetics, Local ; Ropivacaine (7IO5LYA57N) ; Sufentanil (AFE2YW0IIZ) |
| Language | English |
| Publishing date | 2001-06-08 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 80032-6 |
| ISSN | 1526-7598 ; 0003-2999 |
| ISSN (online) | 1526-7598 |
| ISSN | 0003-2999 |
| DOI | 10.1213/01.ANE.0000067404.84486.7A |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Uk I Zs.78: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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| Zs.MO 149: Show issues |
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(In: Musahl, Hans Peter; Eisenhauer, Thomas (Ed.), Psychologie der Arbeitsssicherheit. Beiträge zur Förderung von Sicherheit und Gesundheit in Arbeitssystemen. 10. Workshop 1999 (S. 399-501). Heidelberg: Asanger)
2000
Abstract: ... werden - Ergebnisse einer Feldstudie mit Instandhaltern. (8) U. Nickel und K.-T. Wenchel: Entwicklung ...
| Title translation | Continuing education measures and their evaluation in the field of work and health protection |
|---|---|
| Series title | In: Musahl, Hans Peter; Eisenhauer, Thomas (Ed.), Psychologie der Arbeitsssicherheit. Beiträge zur Förderung von Sicherheit und Gesundheit in Arbeitssystemen. 10. Workshop 1999 (S. 399-501). Heidelberg: Asanger |
| Abstract | Ausgewählte Tagungsbeiträge (10. Workshop "Psychologie der Arbeitssicherheit 1999 in Mannheim) zu Weiterbildungsmaßnahmen im Bereich des Arbeits- und Gesundheitsschutzes und deren Evaluation werden dokumentiert. Im Zentrum der Kurzbeiträge stehen Erfahrungen und empirische Daten, die mit spezifischen Weiterbildungsmaßnahmen in einzelnen Betrieben gewonnen wurden. - Inhalt: (1) H. Bienek: Effizienzsteigerung bei der Fort- und Weiterbildung im Arbeitssschutz durch neue Seminarform. (2) I. Dienstbühl: Sicherheit, Gesundheit und Hygiene für Auszubildende kleiner und mittelgroßer Unternehmen der Gastronomie bei gleichzeitiger Förderung der fachpraktischen Qualifikation. (3) B. Schlote: Erlebnisorientierte Hautschutzschulung. (4) S. Gregersen: Gesundheit als Führungsaufgabe - Seminare für das obere Management. (5) G. Strobel, K.-H. Noetel, P. Jackisch und F. Koschel: Lifelong Learning - Neue Wege zur Förderung von Sicherheit und Gesundheit. (6) U. Keil: Sozial-kognitive Lernprozesse zur Arbeitssicherheit. (7) E. Hemmann, H. Merboth und P. Richter: Sicherheitsrelevante Gestaltungserfordernisse müssen erst einmal erkannt werden - Ergebnisse einer Feldstudie mit Instandhaltern. (8) U. Nickel und K.-T. Wenchel: Entwicklung eines videogestützten Lehrkonzepts: "Gesund und sicher am Arbeitsplatz". (9) H. Beck: Vorbereitende Maßnahmen zur Referentenqualifizierung im Rahmen der Neukonzeption der Ausbildung von Fachkräften für Arbeitssicherheit. (10) P. Börmann und R. Hering: Gefahrenkenntnis in der betrieblichen Praxis. (11) D. Bratge und U. Gerber: Evaluation des Ausbildungskonzeptes im Unternehmermodell. (12) M. Lasser: Empirische Untersuchungen zur Qualität der berufsgenossenschaftlichen Ausbildung. (13) B. Rüttinger und B. S. Wiese: Dienstleistungsqualität von Trainingsmaßnahmen. (14) F. Kalfhues: Buch oder CD-ROM? - Eine Vergleichsstudie. |
| Keywords | Continuing Education ; Gesundheit am Arbeitsplatz ; Gesundheitsförderung ; Health Promotion ; Human Resource Management ; Inservice Training ; Occupational Health ; Occupational Safety ; Personal-Management ; Prevention ; Program Evaluation ; Programmevaluation ; Prävention ; Sicherheit am Arbeitsplatz ; Weiterbildung ; Weiterbildung im Beruf |
| Language | German |
| Document type | Article |
| ISBN | 3-89334-356-3 ; 978-3-89334-356-0 |
| Database | PSYNDEX |
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