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  1. Article ; Online: Reconstructive management of total lower lip defects with a modified gate flap at the “Dr. Eduardo Liceaga” General Hospital of Mexico

    Héctor Ortíz-Martínez / Rodolfo L. Ríos-Lara y López

    Revista Médica del Hospital General de México, Vol 85, Iss

    2022  Volume 4

    Abstract: Objective: A surgical proposal is presented for the management of total lower lip defects based on the technique described in 1980 by Fujimori, called gate flap. The most common cause of total lip defects is oncological resections; likewise, epidermoid ... ...

    Abstract Objective: A surgical proposal is presented for the management of total lower lip defects based on the technique described in 1980 by Fujimori, called gate flap. The most common cause of total lip defects is oncological resections; likewise, epidermoid cancer represents more than 90% of the types of cancer in the lip. Reconstructive management after excisional treatment requires extensive anatomical knowledge of the area, and free flaps are currently the gold standard for total lower lip defects. It is for this reason that after a review of the surgical options described, we made modifications to the Fujimori gate flap. Materials and Methods: The gate flap modified by us consists in a unilateral musculocutaneous flap, generating less donor site morbidity, and adding a palmaris longus tendon graft, performing a double pulley system for reconstruction of the oral sphincter, achieving adequate fluid continence. Three cases of elderly patients with total defects of the lower lip are presented. Results: We found that Modified Gate Flap are superior to the gold standard (radial free flap). Achieving adequate skin coverage, restoration of the oral sphincter, shorter surgical time, they do not present complications associated with the procedure. Conclusions: The ideal reconstruction should have not only an adequate aesthetic appearance, but also the restoration of function, associated with the lowest incidence of complications, with reproducible and constant results, which lead to a high degree of satisfaction of the patient and the surgical team; Same scenario we found with our therapeutic option.
    Keywords Lower lip reconstruction. Gate flap. Lip neoplasia. Lip diseases. Reconstructive surgical procedures ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Permanyer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: SARS-CoV-2 Variants and Clinical Outcomes: A Systematic Review.

    Mendiola-Pastrana, Indira R / López-Ortiz, Eduardo / Río de la Loza-Zamora, José G / González, James / Gómez-García, Anel / López-Ortiz, Geovani

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 2

    Abstract: Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have emerged that potentially affect transmissibility, severity, and immune evasion in infected individuals. In the present systematic review, the impact of different SARS-CoV- ... ...

    Abstract Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have emerged that potentially affect transmissibility, severity, and immune evasion in infected individuals. In the present systematic review, the impact of different SARS-CoV-2 variants on clinical outcomes is analyzed.
    Methods: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020. Two databases (PubMed and ScienceDirect) were searched for original articles published from 1 January 2020 to 23 November 2021. The articles that met the selection criteria were appraised according to the Newcastle-Ottawa Quality Assessment Scale.
    Results: Thirty-three articles were included, involving a total of 253,209 patients and 188,944 partial or complete SARS-CoV-2 sequences. The most reported SARS-CoV-2 variants showed changes in the spike protein, N protein, RdRp and NSP3. In 28 scenarios, SARS-CoV-2 variants were found to be associated with a mild to severe or even fatal clinical outcome, 15 articles reported such association to be statistically significant. Adjustments in eight of them were made for age, sex and other covariates.
    Conclusions: SARS-CoV-2 variants can potentially have an impact on clinical outcomes; future studies focused on this topic should consider several covariates that influence the clinical course of the disease.
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12020170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: From the handling of an outbreak by an unknown pathogen in Wuhan to the preparedness and response in the face of the emergence of Covid-19 in Mexico.

    López-Ortiz, Eduardo / López-Ortiz, Geovani / Mendiola-Pastrana, Indira R / Mazón-Ramírez, Juan J / Díaz-Quiñonez, José A

    Gaceta medica de Mexico

    2020  Volume 156, Issue 2, Page(s) 132–137

    Abstract: On December 31, 2019, the Chinese health authorities informed the international community, through the mechanisms established by the World Health Organization (WHO), of a pneumonia epidemic of unknown etiology in Wuhan, Hubei Province. The first cases ... ...

    Title translation De la atención de un brote por un patógeno desconocido en Wuhan hasta la preparación y respuesta ante la posible emergencia del 2019-nCoV en México.
    Abstract On December 31, 2019, the Chinese health authorities informed the international community, through the mechanisms established by the World Health Organization (WHO), of a pneumonia epidemic of unknown etiology in Wuhan, Hubei Province. The first cases were reported early in that month and were linked to a history of having visited a market where food and live animals are sold. On January 7, 2020, isolation and identification of the culprit pathogen was achieved using next-generation sequencing, while the number of affected subjects continued to rise. The publication of full-genomes of the newly identified coronavirus (initially called 2019-nCoV, now called SARS-CoV2) in public and private databases, of standardized diagnostic protocols and of the clinical-epidemiological information generated will allow addressing the Public Health Emergency of International Concern (PHEIC), declared on January 30 by the WHO. With this document, we intend to contribute to the characterization of the pneumonia epidemic, now designated coronavirus disease (Covid-19) review the strengths Mexico has in the global health concert and invite health professionals to join the preparedness and response activities in the face of this emergency.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Disease Outbreaks ; Global Health ; Humans ; Mexico ; Pandemics ; Pneumonia, Viral/epidemiology ; Public Health ; SARS-CoV-2 ; World Health Organization
    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M20000346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: SARS-CoV-2 Reinfection among Healthcare Workers in Mexico: Case Report and Literature Review.

    Garduño-Orbe, Brenda / Sánchez-Rebolledo, Juan Manuel / Cortés-Rafael, Mustafá / García-Jiménez, Yuliana / Perez-Ortiz, Marcelina / Mendiola-Pastrana, Indira Rocío / López-Ortiz, Eduardo / López-Ortiz, Geovani

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 5

    Abstract: Since the onset of the COVID-19 pandemic, there have been multiple questions regarding reinfections associated with SARS-CoV-2. Healthcare workers on duty, due to overexposure in environments where there are more cases of COVID-19, are more prone to ... ...

    Abstract Since the onset of the COVID-19 pandemic, there have been multiple questions regarding reinfections associated with SARS-CoV-2. Healthcare workers on duty, due to overexposure in environments where there are more cases of COVID-19, are more prone to become infected by this virus. Here, we report 4 cases that meet the definition of clinical reinfection by SARS-CoV-2, as well as a literature review on this subject; all occurred in healthcare workers in Acapulco Guerrero, Mexico who provide their services in a hospital that cares for patients with COVID-19. The time between the manifestation of the first and second infection for each case was 134, 129, 107 and 82 days, all patients presented symptomatology in both events. The time between remission of the first infection and onset of second infection was 108, 109, 78 and 67 days for each case, while the time to confirmation by reverse transcription polymerase chain reaction (RT-PCR) between infections was 134, 124, 106 and 77 days. In two of the four cases the reinfection resulted in a more severe case, while in the remaining two cases the manifestation of symptoms and complications was similar to that presented in the first infection. Given this scenario, greater care is needed in the management of the pandemic caused by SARS-CoV-2 to protect healthcare workers and the general public from risks and complications caused by a possible reinfection by SARS-CoV-2.
    MeSH term(s) COVID-19 ; Health Personnel ; Humans ; Mexico/epidemiology ; Pandemics ; Reinfection ; SARS-CoV-2
    Language English
    Publishing date 2021-05-03
    Publishing country Switzerland
    Document type Case Reports ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57050442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Errores más comunes al redactar artículos médicos originales.

    Hernández-Vargas, Adriana / Pérez-Manjarrez, Francia Estefanía / Mendiola-Pastrana, Indira Rocío / López-Ortiz, Eduardo / López-Ortiz, Geovani

    Gaceta medica de Mexico

    2019  Volume 155, Issue 6, Page(s) 635–640

    Abstract: One of the skills that is more in need to be strengthened in the medical area is the dissemination of knowledge. For this reason, it is necessary to provide elements that promote training in scientific writing. Identifying the most common problems when ... ...

    Abstract One of the skills that is more in need to be strengthened in the medical area is the dissemination of knowledge. For this reason, it is necessary to provide elements that promote training in scientific writing. Identifying the most common problems when writing medical original articles for publication will provide useful resources that should contribute to the generation of knowledge. There are multiple reasons that intervene for an original article not to be accepted in a medical journal, among which failure to follow instructions for authors and methodological, design and structural problems stand out. However, the aspect that most influences and that is seldom pointed out, is inadequate writing of research manuscripts, which becomes evident in the different sections that make up manuscripts. All the above-mentioned factors are the responsibility of the authors, and therefore must be taken care of properly. The purpose of this article is to identify the most common mistakes when writing original medical manuscripts, which, if avoided, will increase the possibility for research papers to be accepted for publication.
    MeSH term(s) Authorship/standards ; Humans ; Information Dissemination/methods ; Periodicals as Topic/standards ; Publishing/standards ; Writing/standards
    Language English
    Publishing date 2019-12-02
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.19005172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: SARS-CoV-2 Variants and Clinical Outcomes

    Indira R. Mendiola-Pastrana / Eduardo López-Ortiz / José G. Río de la Loza-Zamora / James González / Anel Gómez-García / Geovani López-Ortiz

    Life, Vol 12, Iss 170, p

    A Systematic Review

    2022  Volume 170

    Abstract: Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have emerged that potentially affect transmissibility, severity, and immune evasion in infected individuals. In the present systematic review, the impact of different SARS-CoV-2 ...

    Abstract Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have emerged that potentially affect transmissibility, severity, and immune evasion in infected individuals. In the present systematic review, the impact of different SARS-CoV-2 variants on clinical outcomes is analyzed. Methods: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020. Two databases (PubMed and ScienceDirect) were searched for original articles published from 1 January 2020 to 23 November 2021. The articles that met the selection criteria were appraised according to the Newcastle–Ottawa Quality Assessment Scale. Results: Thirty-three articles were included, involving a total of 253,209 patients and 188,944 partial or complete SARS-CoV-2 sequences. The most reported SARS-CoV-2 variants showed changes in the spike protein, N protein, RdRp and NSP3. In 28 scenarios, SARS-CoV-2 variants were found to be associated with a mild to severe or even fatal clinical outcome, 15 articles reported such association to be statistically significant. Adjustments in eight of them were made for age, sex and other covariates. Conclusions: SARS-CoV-2 variants can potentially have an impact on clinical outcomes; future studies focused on this topic should consider several covariates that influence the clinical course of the disease.
    Keywords SARS-CoV-2 variants ; mutations ; clinical outcomes ; outcome assessment ; health care ; severity ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Peer-Review and Rejection Causes in Submitting Original Medical Manuscripts.

    Mendiola Pastrana, Indira Rocío / Hernández, Adriana Vargas / Pérez Manjarrez, Francia Estefanía / López, Eduardo Ortiz / Romero-Henríquez, Luisa Fernanda / López-Ortiz, Geovani

    The Journal of continuing education in the health professions

    2020  Volume 40, Issue 3, Page(s) 182–186

    Abstract: The purpose of specialized medical journals is to accurately disseminate the results of new research. The peer-review process is crucial for journals to be able to fulfill this purpose. Although the peer-review determines whether scientific papers are ... ...

    Abstract The purpose of specialized medical journals is to accurately disseminate the results of new research. The peer-review process is crucial for journals to be able to fulfill this purpose. Although the peer-review determines whether scientific papers are accepted or rejected for publication, for many authors is a not well known process in its entirety. Many journals have focused on educating their audience about how and what is assessed during peer-review, nevertheless, the rate of manuscripts rejected because of easily-avoidable causes related to this, remains high. In this paper, we describe the process that specialized journals use to assess original medical manuscripts and list the main causes of paper rejection. Practicing physicians and medical students who wish to report their research results stand to benefit if they can identify and early avoid on the issues that most often arise during the peer-review process.
    MeSH term(s) Humans ; Peer Review/methods ; Peer Review/standards ; Publishing/standards ; Publishing/trends ; Writing/standards
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639445-0
    ISSN 1554-558X ; 0894-1912
    ISSN (online) 1554-558X
    ISSN 0894-1912
    DOI 10.1097/CEH.0000000000000295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: De la atención de un brote por un patógeno desconocido en Wuhan hasta la preparación y respuesta ante la posible emergencia del 2019-nCoV en México./ From the handling of an outbreak by an unknown pathogen in Wuhan to the preparedness and response in the face of the emergence of Covid-19 in Mexico

    López-Ortiz, Eduardo / López-Ortiz, Geovani / Mendiola-Pastrana, Indira R / Mazón-Ramírez, Juan J / Díaz-Quiñonez, José A

    Gac Med Mex

    Abstract: On December 31, 2019, the Chinese health authorities informed the international community, through the mechanisms established by the World Health Organization (WHO), of a pneumonia epidemic of unknown etiology in Wuhan, Hubei Province. The first cases ... ...

    Abstract On December 31, 2019, the Chinese health authorities informed the international community, through the mechanisms established by the World Health Organization (WHO), of a pneumonia epidemic of unknown etiology in Wuhan, Hubei Province. The first cases were reported early in that month and were linked to a history of having visited a market where food and live animals are sold. On January 7, 2020, isolation and identification of the culprit pathogen was achieved using next-generation sequencing, while the number of affected subjects continued to rise. The publication of full-genomes of the newly identified coronavirus (initially called 2019-nCoV, now called SARS-CoV2) in public and private databases, of standardized diagnostic protocols and of the clinical-epidemiological information generated will allow addressing the Public Health Emergency of International Concern (PHEIC), declared on January 30 by the WHO. With this document, we intend to contribute to the characterization of the pneumonia epidemic, now designated coronavirus disease (Covid-19) review the strengths Mexico has in the global health concert and invite health professionals to join the preparedness and response activities in the face of this emergency.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #63831
    Database COVID19

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  9. Article ; Online: SARS-CoV-2 Reinfection among Healthcare Workers in Mexico

    Brenda Garduño-Orbe / Juan Manuel Sánchez-Rebolledo / Mustafá Cortés-Rafael / Yuliana García-Jiménez / Marcelina Perez-Ortiz / Indira Rocío Mendiola-Pastrana / Eduardo López-Ortiz / Geovani López-Ortiz

    Medicina, Vol 57, Iss 442, p

    Case Report and Literature Review

    2021  Volume 442

    Abstract: Since the onset of the COVID-19 pandemic, there have been multiple questions regarding reinfections associated with SARS-CoV-2. Healthcare workers on duty, due to overexposure in environments where there are more cases of COVID-19, are more prone to ... ...

    Abstract Since the onset of the COVID-19 pandemic, there have been multiple questions regarding reinfections associated with SARS-CoV-2. Healthcare workers on duty, due to overexposure in environments where there are more cases of COVID-19, are more prone to become infected by this virus. Here, we report 4 cases that meet the definition of clinical reinfection by SARS-CoV-2, as well as a literature review on this subject; all occurred in healthcare workers in Acapulco Guerrero, Mexico who provide their services in a hospital that cares for patients with COVID-19. The time between the manifestation of the first and second infection for each case was 134, 129, 107 and 82 days, all patients presented symptomatology in both events. The time between remission of the first infection and onset of second infection was 108, 109, 78 and 67 days for each case, while the time to confirmation by reverse transcription polymerase chain reaction (RT-PCR) between infections was 134, 124, 106 and 77 days. In two of the four cases the reinfection resulted in a more severe case, while in the remaining two cases the manifestation of symptoms and complications was similar to that presented in the first infection. Given this scenario, greater care is needed in the management of the pandemic caused by SARS-CoV-2 to protect healthcare workers and the general public from risks and complications caused by a possible reinfection by SARS-CoV-2.
    Keywords COVID-19 ; reinfection ; SARS-CoV-2 ; healthcare workers ; clinical reinfection ; Medicine (General) ; R5-920
    Subject code 360
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Sensibilización a aeroalérgenos en pacientes con rinitis alérgica en Aguascalientes, México.

    Suárez-Gutiérrez, Marcos / Macías-Garza, Jorge Eduardo / López-Ortiz, Daniela Jazmín / Fuentes, Brenda / Álvarez-Cardona, Aristóteles

    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

    2020  Volume 66, Issue 4, Page(s) 388–393

    Abstract: Background: Allergic rhinitis is the most common allergic disease worldwide and it is caused by a reaction of hypersensitivity to aeroallergens. To our knowledge, there aren't any previous studies of aeroallergenic sensitization in Aguascalientes, ... ...

    Title translation Sensitization to aeroallergens in patients with allergic rhinitis in Aguascalientes, Mexico.
    Abstract Background: Allergic rhinitis is the most common allergic disease worldwide and it is caused by a reaction of hypersensitivity to aeroallergens. To our knowledge, there aren't any previous studies of aeroallergenic sensitization in Aguascalientes, Mexico.
    Objective: To describe the sensitization to aeroallergens in patients with allergic rhinitis who have been treated at a private clinic in Aguascalientes, Mexico.
    Methods: A descriptive, cross-sectional and retrospective study was done in which patients diagnosed with allergic rhinitis were included. Skin prick tests with 32 allergenic extracts were carried out and the frequencies at each were determined.
    Results: In total, 350 patients were analyzed. The most frequent aeroallergens were grass pollens (74.8%), followed by tree pollens (64.8%) and dust mites Dermatophagoides pteronyssinus (64%). The group of patients under 20 years of age was predominant (67.1%), followed by the group of 21 to 40 years old (22.5%).
    Conclusions: This research provides information about regional patterns of sensitization, which shall facilitate diagnostic tests in the region and the best practices of specific immunotherapy.
    MeSH term(s) Adolescent ; Adult ; Aged ; Air Pollutants/immunology ; Allergens/immunology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Infant ; Male ; Mexico ; Middle Aged ; Retrospective Studies ; Rhinitis, Allergic/immunology ; Young Adult
    Chemical Substances Air Pollutants ; Allergens
    Language Spanish
    Publishing date 2020-02-26
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 639125-4
    ISSN 0002-5151
    ISSN 0002-5151
    DOI 10.29262/ram.v66i4.634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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