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Article: Clinical aspects of binge eating disorder: A cross-sectional mixed-methods study of binge eating disorder experts' perspectives.

Bray, Brenna / Sadowski, Adam / Bray, Chris / Bradley, Ryan / Zwickey, Heather

2023 Volume 13, Page(s) 1087165

Abstract: Introduction: Research on binge eating disorder continues to evolve and advance our understanding of recurrent binge eating.: Methods: This mixed-methods, cross-sectional survey aimed to collect information from experts in the field about clinical ... ...

Abstract	Introduction: Research on binge eating disorder continues to evolve and advance our understanding of recurrent binge eating. Methods: This mixed-methods, cross-sectional survey aimed to collect information from experts in the field about clinical aspects of adult binge eating disorder pathology. Fourteen experts in binge eating disorder research and clinical care were identified based on receipt of relevant federal funding, PubMed-indexed publications, active practice in the field, leadership in relevant societies, and/or clinical and popular press distinction. Anonymously recorded semi-structured interviews were analyzed by ≥2 investigators using reflexive thematic analysis and quantification. Results: Identified themes included: (1) obesity (100%); (2) intentional/voluntary or unintentional/involuntary food/eating restriction (100%); (3) negative affect, emotional dysregulation, and negative urgency (100%); (4) diagnostic heterogeneity and validity (71%); (5) paradigm shifts in understanding binge eating disorder (29%); and (6) research gaps/future directives (29%). Discussion: Overall, experts call for a better understanding of the relationship between binge eating disorder and obesity, including a need for clarification around the extent to which the two health issues are separate vs. related/overlapping. Experts also commonly endorse food/eating restriction and emotion dysregulation as important components of binge eating disorder pathology, which aligns with two common models of binge eating disorder conceptualization (e.g., dietary restraint theory and emotion/affect regulation theory). A few experts spontaneously identified several paradigm shifts in our understanding of who can have an eating disorder (beyond the anorexi-centric "thin, White, affluent,
Language	English
Publishing date	2023-02-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.1087165
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: La technique des anticorps fluorescents pour la mesure des anticorps spécifiques des parasites du paludisme / par A. Voller, R. S. Bray

Voller, A / Bray, R. S / World Health Organization

1962

Abstract: Documents : WHO/Mal/346, WHO/Mal/347 (WHO/Vector Control/3), WHO/Mal/348-356, WHO/Mal/357 (WHO/Vector Control/4), WHO/Mal/358-359, WHO/Mal/360 (WHO/Vector Control/11), WHO/Mal/361 (WHO/Vector Control/13), WHO/Mal/362 (WHO/Vector Control/9), WHO/Mal/363- ... ...

Abstract	Documents : WHO/Mal/346, WHO/Mal/347 (WHO/Vector Control/3), WHO/Mal/348-356, WHO/Mal/357 (WHO/Vector Control/4), WHO/Mal/358-359, WHO/Mal/360 (WHO/Vector Control/11), WHO/Mal/361 (WHO/Vector Control/13), WHO/Mal/362 (WHO/Vector Control/9), WHO/Mal/363-367, WHO/Mal/368 (WHO/EBL/5), WHO/Mal/369, bound in 1 vol WHO/Mal/353 10 p. (ill., tables).
Keywords	Malaria ; Fluorescent antibody technique ; Antibody formation ; Parasites ; Parasitic Diseases and their Control ; prevention and control parasitology
Language	English
Publisher	Genève : Organisation mondiale de la Santé
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: La technique des anticorps fluorescents pour la mesure des anticorps spécifiques des parasites du paludisme / par A. Voller, R. S. Bray

Voller, A / Bray, R. S / World Health Organization

1962

Abstract	Documents : WHO/Mal/346, WHO/Mal/347 (WHO/Vector Control/3), WHO/Mal/348-356, WHO/Mal/357 (WHO/Vector Control/4), WHO/Mal/358-359, WHO/Mal/360 (WHO/Vector Control/11), WHO/Mal/361 (WHO/Vector Control/13), WHO/Mal/362 (WHO/Vector Control/9), WHO/Mal/363-367, WHO/Mal/368 (WHO/EBL/5), WHO/Mal/369, bound in 1 vol WHO/Mal/353 10 p. (ill., tables).
Keywords	Malaria ; Fluorescent Antibody Technique ; Antibody Formation ; Parasites ; Parasitic Diseases and their Control ; prevention and control parasitology
Language	English
Publisher	Organisation mondiale de la Santé
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mitigating the impacts of racism on Indigenous wellbeing through human rights, legislative and health policy reform.

Dudgeon, Pat / Bray, Abigail / Walker, Roz

The Medical journal of Australia

2023 Volume 218, Issue 5, Page(s) 203–205

MeSH term(s)	Humans ; Racism/prevention & control ; Health Policy ; Human Rights ; Health Services, Indigenous
Language	English
Publishing date	2023-03-05
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	186082-3
ISSN	1326-5377 ; 0025-729X
ISSN (online)	1326-5377
ISSN	0025-729X
DOI	10.5694/mja2.51862
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Ua VI Zs.398: Show issues

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Article ; Online: Family screening for bicuspid aortic valve and aortic dilatation: a meta-analysis.

Bray, Jonathan J H / Freer, Rosie / Pitcher, Alex / Kharbanda, Rajesh

European heart journal

2023 Volume 44, Issue 33, Page(s) 3152–3164

Abstract: Aims: International guidelines recommend screening of first-degree relatives (FDR) of people with bicuspid aortic valves (BAVs). However, the prevalence of BAV and of aortic dilatation amongst family members is uncertain.: Methods and results: A ... ...

Abstract	Aims: International guidelines recommend screening of first-degree relatives (FDR) of people with bicuspid aortic valves (BAVs). However, the prevalence of BAV and of aortic dilatation amongst family members is uncertain. Methods and results: A systematic review and meta-analysis of original reports of screening for BAV. Databases including MEDLINE, Embase, and Cochrane CENTRAL were searched from inception to December 2021 using relevant search terms. Data were sought on the screened prevalence of BAV and aortic dilatation. The protocol was specified prior to the searches being performed, and standard meta-analytic techniques were used. Twenty-three observational studies met inclusion criteria (n = 2297 index cases; n = 6054 screened relatives). The prevalence of BAV amongst relatives was 7.3% [95% confidence interval (CI) 6.1%-8.6%] overall and per family was 23.6% (95% CI 18.1%-29.5%). The prevalence of aortic dilatation amongst relatives was 9.4% (95% CI 5.7%-13.9%). Whilst the prevalence of aortic dilatation was particularly high in relatives with BAV (29.2%; 95% CI 15.3%-45.1%), aortic dilatation alongside tricuspid aortic valves was a more frequent finding, as there were many more family members with tricuspid valves than BAV. The prevalence estimate amongst relatives with tricuspid valves (7.0%; 95% CI 3.2%-12.0%) was higher than reported in the general population. Conclusion: Screening family members of people with BAV can identify a cohort substantially enriched for the presence of bicuspid valve, aortic enlargement, or both. The implications for screening programmes are discussed, including in particular the substantial current uncertainties regarding the clinical implications of aortic findings.
MeSH term(s)	Humans ; Bicuspid Aortic Valve Disease ; Heart Valve Diseases/epidemiology ; Heart Valve Diseases/genetics ; Heart Valve Diseases/diagnosis ; Dilatation ; Aortic Valve ; Aortic Diseases/diagnosis ; Dilatation, Pathologic/epidemiology ; Retrospective Studies
Language	English
Publishing date	2023-06-07
Publishing country	England
Document type	Systematic Review ; Meta-Analysis ; Journal Article
ZDB-ID	603098-1
ISSN	1522-9645 ; 0195-668X
ISSN (online)	1522-9645
ISSN	0195-668X
DOI	10.1093/eurheartj/ehad320
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Zs.A 1563: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 640: Show issues

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Article ; Online: Exposure to Green and Historic Urban Environments and Mental Well-Being: Results from EEG and Psychometric Outcome Measures.

Reece, Rebecca / Bornioli, Anna / Bray, Isabelle / Alford, Chris

International journal of environmental research and public health

2022 Volume 19, Issue 20

Abstract: Previous studies have identified the benefits of exposure to green or historic environments using qualitative methods and psychometric measures, but studies using a combination of measures are lacking. This study builds on current literature by focusing ... ...

Abstract	Previous studies have identified the benefits of exposure to green or historic environments using qualitative methods and psychometric measures, but studies using a combination of measures are lacking. This study builds on current literature by focusing specifically on green and historic urban environments and using both psychological and physiological measures to investigate the impact of virtual exposure on well-being. Results from the psychological measures showed that the presence of historic elements was associated with a significantly stronger recuperation of hedonic tone (
MeSH term(s)	Humans ; Psychometrics ; Stress, Psychological ; Mental Health ; Outcome Assessment, Health Care ; Electroencephalography
Language	English
Publishing date	2022-10-11
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph192013052
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Article ; Online: Assessing the relationship between topical corticosteroid phobia and susceptibility to misinformation in patients with atopic dermatitis.

Hrin, M L / Bray, J K / Fleischer, A B / Feldman, S R

Journal of the European Academy of Dermatology and Venereology : JEADV

2021 Volume 36, Issue 2, Page(s) e115–e118

MeSH term(s)	Administration, Topical ; Adrenal Cortex Hormones/therapeutic use ; Communication ; Dermatitis, Atopic/drug therapy ; Eczema ; Glucocorticoids/therapeutic use ; Humans ; Phobic Disorders
Chemical Substances	Adrenal Cortex Hormones ; Glucocorticoids
Language	English
Publishing date	2021-09-25
Publishing country	England
Document type	Letter
ZDB-ID	1128828-0
ISSN	1468-3083 ; 0926-9959
ISSN (online)	1468-3083
ISSN	0926-9959
DOI	10.1111/jdv.17663
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Zs.A 3492: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 413: Show issues

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Article ; Online: Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease.

Zitomersky, Naamah / Chi, Lisa / Liu, Enju / Bray, Kurtis R / Papamichael, Konstantinos / Cheifetz, Adam S / Snapper, Scott B / Bousvaros, Athos / Silvester, Jocelyn A

Journal of pediatric gastroenterology and nutrition

2023 Volume 78, Issue 2, Page(s) 261–271

Abstract: Background: Infliximab (IFX) use is limited by loss of response often due to the development of anti-IFX antibodies and low drug levels.: Methods: We performed a single center prospective observational cohort study of pediatric and young adult ... ...

Abstract	Background: Infliximab (IFX) use is limited by loss of response often due to the development of anti-IFX antibodies and low drug levels. Methods: We performed a single center prospective observational cohort study of pediatric and young adult subjects with inflammatory bowel disease (IBD) on IFX with over 3 years of follow-up. Infliximab levels (IFXL) and antibodies to infliximab (ATI) were measured throughout the study. Subjects were followed until IFX was discontinued. Results: We enrolled 219 subjects with IBD (184: Crohn's disease; 33: Ulcerative colitis; and 2 Indeterminant colitis; 84 female, median age 14.4 years, 37% on concomitant immunomodulator). Nine hundred and nineteen serum samples (mean 4.2 ± 2.1 per patient) were tested for IFXL and ATI. During the study, 31 (14%) subjects discontinued IFX. Sixty patients had ATI. Twenty-two of those 60 patients with ATI discontinued IFX; 14 of 31 patients who discontinued IFX had detectable ATI at study onset. The combination of ATI and IFXL < 5 µg/mL at study entry was associated with the highest risk of drug discontinuation (hazard ratios [HR] ATI 4.27 [p < 0.001] and IFXL < 5 µg/mL [HR]: 3.2 p = 0.001). Patients with IFXL 5-10 µg/mL had the lowest rate of discontinuation (6%). IFX dose escalation eliminated ATI in 21 of 60 subjects. Conclusions: ATI is a strong predictor of needing to stop IFX use and inversely correlates with IFXL. Detection of ATI during therapeutic drug monitoring postinduction but also periodically during maintenance therapy identifies individuals who may benefit from IFX dose escalation and/or the addition of an immunomodulator, as these interventions may reduce or eliminate ATI.
MeSH term(s)	Young Adult ; Humans ; Child ; Female ; Adolescent ; Infliximab ; Prospective Studies ; Inflammatory Bowel Diseases/drug therapy ; Crohn Disease ; Colitis, Ulcerative ; Antibodies ; Drug Monitoring ; Immunologic Factors/therapeutic use ; Gastrointestinal Agents
Chemical Substances	Infliximab (B72HH48FLU) ; Antibodies ; Immunologic Factors ; Gastrointestinal Agents
Language	English
Publishing date	2023-12-27
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	603201-1
ISSN	1536-4801 ; 0277-2116
ISSN (online)	1536-4801
ISSN	0277-2116
DOI	10.1002/jpn3.12074
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Zs.A 1728: Show issues

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Article ; Online: Effect of tirzepatide on body fat distribution pattern in people with type 2 diabetes.

Cariou, Bertrand / Linge, Jennifer / Neeland, Ian J / Dahlqvist Leinhard, Olof / Petersson, Mikael / Fernández Landó, Laura / Bray, Ross / Rodríguez, Ángel

Diabetes, obesity & metabolism

2024

Abstract: Aims: To describe the overall fat distribution patterns independent of body mass index (BMI) in participants with type 2 diabetes (T2D) in the SURPASS-3 MRI substudy by comparison with sex- and BMI-matched virtual control groups (VCGs) derived from the ... ...

Abstract	Aims: To describe the overall fat distribution patterns independent of body mass index (BMI) in participants with type 2 diabetes (T2D) in the SURPASS-3 MRI substudy by comparison with sex- and BMI-matched virtual control groups (VCGs) derived from the UK Biobank imaging study at baseline and Week 52. Methods: For each study participant at baseline and Week 52 (N = 296), a VCG of ≥150 participants with the same sex and similar BMI was identified from the UK Biobank imaging study (N = 40 172). Average visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (aSAT) and liver fat (LF) levels and the observed standard deviations (SDs; standardized normal z-scores: z-VAT, z-aSAT and z-LF) were calculated based on the matched VCGs. Differences in z-scores between baseline and Week 52 were calculated to describe potential shifts in fat distribution pattern independent of weight change. Results: Baseline fat distribution patterns were similar across pooled tirzepatide (5, 10 and 15 mg) and insulin degludec (IDeg) arms. Compared with matched VCGs, SURPASS-3 participants had higher baseline VAT (mean [SD] z-VAT +0.42 [1.23]; p < 0.001) and LF (z-LF +1.24 [0.92]; p < 0.001) but similar aSAT (z-aSAT -0.13 [1.11]; p = 0.083). Tirzepatide-treated participants had significant decreases in z-VAT (-0.18 [0.58]; p < 0.001) and z-LF (-0.54 [0.84]; p < 0.001) but increased z-aSAT (+0.11 [0.50]; p = 0.012). Participants treated with IDeg had a significant change in z-LF only (-0.46 [0.90]; p = 0.001), while no significant changes were observed for z-VAT (+0.13 [0.52]; p = 0.096) and z-aSAT (+0.09 [0.61]; p = 0.303). Conclusion: In this exploratory analysis, treatment with tirzepatide in people with T2D resulted in a significant reduction of z-VAT and z-LF, while z-aSAT was increased from an initially negative value, suggesting a possible treatment-related shift towards a more balanced fat distribution pattern with prominent VAT and LF loss.
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	1454944-x
ISSN	1463-1326 ; 1462-8902
ISSN (online)	1463-1326
ISSN	1462-8902
DOI	10.1111/dom.15566
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Zs.A 5442: Show issues

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Article: Right renal mass diagnosed as focal splenosis; a rare differential for a small renal mass highlighting utility of heat damaged Tc-99m RBC scintigraphy to avoid unnecessary surgery.

Bray, Gerard / Bahadori, Arya / Teng, Roy / McClintock, Dr Scott

Urology case reports

2022 Volume 43, Page(s) 102101

Abstract: Small renal masses (SRM) represent a heterogenous group of kidney lesions that are often found incidentally and can represent a diagnostic dilemma. Herein, we report a 55 year old female who presented with a 25mm right renal mass. She had no symptomology ...

Abstract	Small renal masses (SRM) represent a heterogenous group of kidney lesions that are often found incidentally and can represent a diagnostic dilemma. Herein, we report a 55 year old female who presented with a 25mm right renal mass. She had no symptomology or significant medical history but did report undergoing a traumatic splenectomy 30 years prior. Using Tc-99 m heat damaged RBC scintigraphy, the renal mass was confirmed as focal splenosis. Right sided renal splenosis is almost unheard of. Our case illustrates how good clinical history and correct imaging can prevent unnecessary investigations and surgery for a rare differential of SRMs.
Language	English
Publishing date	2022-05-01
Publishing country	United States
Document type	Case Reports
ZDB-ID	2745459-9
ISSN	2214-4420
ISSN	2214-4420
DOI	10.1016/j.eucr.2022.102101
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