LIVIVO - Search results -

Search results

Result 1 - 10 of total 12

Search options

Book ; Online: Capturing Requirements for a Data Annotation Tool for Intensive Care

Wac, Marceli / Santos-Rodriguez, Raul / McWilliams, Chris / Bourdeaux, Christopher

Experimental User-Centered Design Study

2023

Abstract: Intensive care units (ICUs) are complex and data-rich environments. Data routinely collected in the ICUs provides tremendous opportunities for machine learning, but their use comes with significant challenges. Complex problems may require additional ... ...

Abstract	Intensive care units (ICUs) are complex and data-rich environments. Data routinely collected in the ICUs provides tremendous opportunities for machine learning, but their use comes with significant challenges. Complex problems may require additional input from humans which can be provided through a process of data annotation. Annotation is a complex, time-consuming process that requires domain expertise and technical proficiency. Existing data annotation tools fail to provide an effective solution to this problem. In this study, we investigated clinicians' approach to the annotation task. We focused on establishing the characteristics of the annotation process in the context of clinical data and identifying differences in the annotation workflow between different staff roles. The overall goal was to elicit requirements for a software tool that could facilitate an effective and time-efficient data annotation. We conducted an experiment involving clinicians from the ICUs annotating printed sheets of data. The participants were observed during the task and their actions were analysed in the context of Norman's Interaction Cycle to establish the requirements for the digital tool. The annotation process followed a constant loop of annotation and evaluation, during which participants incrementally analysed and annotated the data. No distinguishable differences were identified between how different staff roles annotate data. We observed preferences towards different methods for applying annotation which varied between different participants and admissions. We established 11 requirements for the digital data annotation tool for the healthcare setting. We conducted a manual data annotation activity to establish the requirements for a digital data annotation tool, characterised the clinicians' approach to annotation and elicited 11 key requirements for effective data annotation software.
Keywords	Computer Science - Human-Computer Interaction
Subject code	005
Publishing date	2023-09-28
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Requirements for a Bespoke Intensive Care Unit Dashboard in Response to the COVID-19 Pandemic: Semistructured Interview Study.

Davidson, Brittany / Ferrer Portillo, Katiuska Mara / Wac, Marceli / McWilliams, Chris / Bourdeaux, Christopher / Craddock, Ian

JMIR human factors

2022 Volume 9, Issue 2, Page(s) e30523

Abstract: Background: Intensive care units (ICUs) around the world are in high demand due to patients with COVID-19 requiring hospitalization. As researchers at the University of Bristol, we were approached to develop a bespoke data visualization dashboard to ... ...

Abstract	Background: Intensive care units (ICUs) around the world are in high demand due to patients with COVID-19 requiring hospitalization. As researchers at the University of Bristol, we were approached to develop a bespoke data visualization dashboard to assist two local ICUs during the pandemic that will centralize disparate data sources in the ICU to help reduce the cognitive load on busy ICU staff in the ever-evolving pandemic. Objective: The aim of this study was to conduct interviews with ICU staff in University Hospitals Bristol and Weston National Health Service Foundation Trust to elicit requirements for a bespoke dashboard to monitor the high volume of patients, particularly during the COVID-19 pandemic. Methods: We conducted six semistructured interviews with clinical staff to obtain an overview of their requirements for the dashboard and to ensure its ultimate suitability for end users. Interview questions aimed to understand the job roles undertaken in the ICU, potential uses of the dashboard, specific issues associated with managing COVID-19 patients, key data of interest, and any concerns about the introduction of a dashboard into the ICU. Results: From our interviews, we found the following design requirements: (1) a flexible dashboard, where the functionality can be updated quickly and effectively to respond to emerging information about the management of this new disease; (2) a mobile dashboard, which allows staff to move around on wards with a dashboard, thus potentially replacing paper forms to enable detailed and consistent data entry; (3) a customizable and intuitive dashboard, where individual users would be able to customize the appearance of the dashboard to suit their role; (4) real-time data and trend analysis via informative data visualizations that help busy ICU staff to understand a patient's clinical trajectory; and (5) the ability to manage tasks and staff, tracking both staff and patient movements, handovers, and task monitoring to ensure the highest quality of care. Conclusions: The findings of this study confirm that digital solutions for ICU use would potentially reduce the cognitive load of ICU staff and reduce clinical errors at a time of notably high demand of intensive health care.
Language	English
Publishing date	2022-04-13
Publishing country	Canada
Document type	Journal Article
ISSN	2292-9495
ISSN (online)	2292-9495
DOI	10.2196/30523
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Curation of an intensive care research dataset from routinely collected patient data in an NHS trust.

McWilliams, Chris / Inoue, Joshua / Wadey, Philip / Palmer, Graeme / Santos-Rodriguez, Raul / Bourdeaux, Christopher

F1000Research

2019 Volume 8, Page(s) 1460

Abstract: In this data note we provide the details of a research database of 4831 adult intensive care patients who were treated in the Bristol Royal Infirmary, UK between 2015 and 2019. The purposes of this publication are to describe the dataset for external ... ...

Abstract	In this data note we provide the details of a research database of 4831 adult intensive care patients who were treated in the Bristol Royal Infirmary, UK between 2015 and 2019. The purposes of this publication are to describe the dataset for external researchers who may be interested in making use of it, and to detail the methods used to curate the dataset in order to help other intensive care units make secondary use of their routinely collected data. The curation involves linkage between two critical care datasets within our hospital and the accompanying code is available online. For reasons of data privacy the data cannot be shared without researchers obtaining appropriate ethical consents. In the future we hope to obtain a data sharing agreement in order to publicly share the de-identified data, and to link our data with other intensive care units who use a Philips clinical information system.
MeSH term(s)	Critical Care ; Data Curation ; Databases, Factual ; Datasets as Topic ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; State Medicine ; United Kingdom
Language	English
Publishing date	2019-08-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.20193.1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: No cheers yet for ethanol in traumatic brain injury.

Bourdeaux, Chris Paul / Marsh, Aidan J

Archives of surgery (Chicago, Ill. : 1960)

2010 Volume 145, Issue 4, Page(s) 403

MeSH term(s)	Alcoholic Intoxication/epidemiology ; Brain Injuries/blood ; Brain Injuries/epidemiology ; Brain Injuries/surgery ; Ethanol/blood ; Glasgow Coma Scale ; Humans ; Prognosis
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2010-04
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80055-7
ISSN	1538-3644 ; 0004-0010 ; 0096-6908 ; 0272-5533
ISSN (online)	1538-3644
ISSN	0004-0010 ; 0096-6908 ; 0272-5533
DOI	10.1001/archsurg.2010.25
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.72: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Randomized controlled trial comparing the effect of 8.4% sodium bicarbonate and 5% sodium chloride on raised intracranial pressure after traumatic brain injury.

Bourdeaux, Chris P / Brown, Jules M

Neurocritical care

2011 Volume 15, Issue 1, Page(s) 42–45

Abstract: Background: Hypertonic sodium chloride solutions are routinely used to control raised intracranial pressure (ICP) after traumatic brain injury but have the potential to cause a hyperchloremic metabolic acidosis. Sodium bicarbonate 8.4% has previously ... ...

Abstract	Background: Hypertonic sodium chloride solutions are routinely used to control raised intracranial pressure (ICP) after traumatic brain injury but have the potential to cause a hyperchloremic metabolic acidosis. Sodium bicarbonate 8.4% has previously been shown to reduce ICP and we have therefore conducted a randomized controlled trial to compare these two solutions. Methods: Patients with severe traumatic brain injury were randomly allocated to receive an equiosmolar dose of either 100 ml of sodium chloride 5% or 85 ml of sodium bicarbonate 8.4% for each episode of intracranial hypertension. ICP and blood pressure were measured continuously. Arterial pCO(2), sodium, chloride, osmolality, and pH were measured at intervals. Results: We studied 20 episodes of intracranial hypertension in 11 patients. Treatments with 8.4% sodium bicarbonate and 5% sodium chloride reduced raised ICP effectively with a significant fall in ICP from baseline at all time points (P < 0.001). There was no significant difference in ICP with time between those episodes treated with 5% sodium chloride or 8.4% sodium bicarbonate, P = 0.504. Arterial pH was raised after treatment with 8.4% sodium bicarbonate. Conclusions: An equiosmolar infusion of 8.4% sodium bicarbonate is as effective as 5% sodium chloride for reduction of raised ICP after traumatic brain injury when infused over 30 min.
MeSH term(s)	Adolescent ; Adult ; Brain Injuries/mortality ; Brain Injuries/physiopathology ; Brain Injuries/therapy ; Cohort Studies ; Female ; Humans ; Intracranial Hypertension/etiology ; Intracranial Hypertension/mortality ; Intracranial Hypertension/therapy ; Male ; Middle Aged ; Saline Solution, Hypertonic/therapeutic use ; Sodium Bicarbonate/therapeutic use ; Sodium Chloride/therapeutic use ; Survival Rate ; Treatment Outcome ; Young Adult
Chemical Substances	Saline Solution, Hypertonic ; Sodium Chloride (451W47IQ8X) ; Sodium Bicarbonate (8MDF5V39QO)
Language	English
Publishing date	2011-02-01
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-011-9512-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6538: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Curation of an intensive care research dataset from routinely collected patient data in an NHS trust. [version 1; peer review

Chris McWilliams / Joshua Inoue / Philip Wadey / Graeme Palmer / Raul Santos-Rodriguez / Christopher Bourdeaux

F1000Research, Vol

2 approved]

2019 Volume 8

Abstract	In this data note we provide the details of a research database of 4831 adult intensive care patients who were treated in the Bristol Royal Infirmary, UK between 2015 and 2019. The purposes of this publication are to describe the dataset for external researchers who may be interested in making use of it, and to detail the methods used to curate the dataset in order to help other intensive care units make secondary use of their routinely collected data. The curation involves linkage between two critical care datasets within our hospital and the accompanying code is available online. For reasons of data privacy the data cannot be shared without researchers obtaining appropriate ethical consents. In the future we hope to obtain a data sharing agreement in order to publicly share the de-identified data, and to link our data with other intensive care units who use a Philips clinical information system.
Keywords	Medicine ; R ; Science ; Q
Subject code	310
Language	English
Publishing date	2019-08-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Sodium bicarbonate lowers intracranial pressure after traumatic brain injury.

Bourdeaux, Chris / Brown, Jules

Neurocritical care

2010 Volume 13, Issue 1, Page(s) 24–28

Abstract: Background: Hypertonic saline is routinely used to treat rises in intracranial pressure (ICP) post-traumatic head injury. Repeated doses often cause a hyperchloremic metabolic acidosis. We investigated the efficacy of 8.4% sodium bicarbonate as an ... ...

Abstract	Background: Hypertonic saline is routinely used to treat rises in intracranial pressure (ICP) post-traumatic head injury. Repeated doses often cause a hyperchloremic metabolic acidosis. We investigated the efficacy of 8.4% sodium bicarbonate as an alternative method of lowering ICP without generating a metabolic acidosis. Methods: We prospectively studied 10 episodes of unprovoked ICP rise in 7 patients treated with 85 ml of 8.4% sodium bicarbonate in place of our usual 100 ml 5% saline. We measured ICP and mean arterial pressure continuously for 6 h after infusion. Serum pH, pCO(2), [Na(+)], and [Cl(-)] were measured at baseline, 30 min, 60 min and then hourly for 6 h. Results: At the completion of the infusion (t = 30 min), the mean ICP fell from 28.5 mmHg (+/-2.62) to 10.33 mmHg (+/-1.89), P < 0.01. Mean ICP remained below 20 mmHg at all time points for 6 h. Mean arterial pressure was unchanged leading to an increased cerebral perfusion pressure at all time points for 6 h post-infusion. pH was elevated from 7.45 +/- 0.05 at baseline to 7.50 +/- 0.05, P < 0.01 at t = 30 min, and remained elevated. Serum [Na(+)] increased from 145.4 +/- 6.02 to 147.1 +/- 6.3 mmol/l, P < 0.01 at t = 30 min. pCO(2) did not change. Conclusions: A single dose of 8.4% sodium bicarbonate is effective at treating rises in ICP for at least 6 h. Serum sodium was raised but without generation of a hyperchloremic metabolic acidosis.
MeSH term(s)	Blood Pressure/drug effects ; Brain Injuries/blood ; Brain Injuries/drug therapy ; Brain Injuries/physiopathology ; Catheterization, Central Venous ; Cerebrovascular Circulation/drug effects ; Chlorides/blood ; Humans ; Hydrogen-Ion Concentration/drug effects ; Intracranial Pressure/drug effects ; Prospective Studies ; Sodium/blood ; Sodium Bicarbonate/administration & dosage ; Time Factors
Chemical Substances	Chlorides ; Sodium Bicarbonate (8MDF5V39QO) ; Sodium (9NEZ333N27)
Language	English
Publishing date	2010-04-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-010-9368-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6538: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Comment on Varpula et al.: Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock.

Bourdeaux, Chris / Hadfield, John

Intensive care medicine

2007 Volume 33, Issue 3, Page(s) 545; author reply 546

MeSH term(s)	Catheterization, Central Venous ; Humans ; Oximetry/methods ; Shock, Septic/blood
Language	English
Publishing date	2007-03
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80387-x
ISSN	1432-1238 ; 0342-4642 ; 0340-0964 ; 0935-1701
ISSN (online)	1432-1238
ISSN	0342-4642 ; 0340-0964 ; 0935-1701
DOI	10.1007/s00134-006-0476-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1089: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Descriptive study of differences in acute kidney injury progression patterns in General and Cardiac Intensive Care Units.

Pachucki, Marcin A / Ghosh, Erina / Eshelman, Larry / Palanisamy, Krishnamoorthy / Gould, Timothy / Thomas, Matthew / Bourdeaux, Chris P

Journal of the Intensive Care Society

2018 Volume 20, Issue 3, Page(s) 216–222

Abstract: Background: Acute kidney injury is common in critically ill patients with detrimental effects on mortality, length of stay and post-discharge outcomes. The Acute Kidney Injury Network developed guidelines based on urine output and serum creatinine to ... ...

Abstract	Background: Acute kidney injury is common in critically ill patients with detrimental effects on mortality, length of stay and post-discharge outcomes. The Acute Kidney Injury Network developed guidelines based on urine output and serum creatinine to classify patients into stages of acute kidney injury. Methods: In this analysis we utilize the Acute Kidney Injury Network guidelines to evaluate the acute kidney injury stage in patients admitted to general and cardiac intensive care units over a period of 18 months. Acute kidney injury stage was calculated in real time hourly based on the guidelines and using these temporal stage scores calculated for the population; the prevalence and progression of acute kidney injury stage was compared between the two units. We hypothesized that the prevalence and progression of acute kidney injury stage between the two units may be different. Results: More cardiac intensive care unit patients had no acute kidney injury (stage <1) during their intensive care unit stay but more cardiac intensive care unit patients developed acute kidney injury (stage >1), compared to the General Intensive Care Unit. Both at intensive care unit admission and discharge, more General Intensive Care Unit patients had acute kidney injury; however, the number of cardiac intensive care unit patients with acute kidney injury was three times higher at discharge than admission. Acute kidney injury developed in a different pattern in the two intensive care units over five days of intensive care unit stay. In the General Intensive Care Unit, acute kidney injury was most prevalent on second day of intensive care unit stay and in cardiac intensive care unit acute kidney injury was most prevalent on the third day of intensive care unit stay. We observed the biggest increase in new acute kidney injury in the first day of General Intensive Care Unit and second day of the cardiac intensive care unit stay. Conclusions: The study demonstrates the different trends of acute kidney injury pattern in general and cardiac intensive care unit patient populations highlighting the earlier development of acute kidney injury on General Intensive Care Unit and more prevalence of acute kidney injury on discharge from cardiac intensive care unit.
Language	English
Publishing date	2018-04-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2701626-2
ISSN	1751-1437 ; 1751-1437
ISSN (online)	1751-1437
ISSN	1751-1437
DOI	10.1177/1751143718771261
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Death from paracetamol overdose despite appropriate treatment with N-acetylcysteine.

Bourdeaux, Chris / Bewley, Jeremy

Emergency medicine journal : EMJ

2007 Volume 24, Issue 5, Page(s) e31

Abstract: A case of death from severe paracetamol poisoning which presented early and received appropriate treatment according to evidence-based guidelines is presented here. It is very rare for patients to die from paracetamol poisoning when they receive N- ... ...

Abstract	A case of death from severe paracetamol poisoning which presented early and received appropriate treatment according to evidence-based guidelines is presented here. It is very rare for patients to die from paracetamol poisoning when they receive N-acetylcysteine (NAC) within 8 h of ingestion. The patient had a marked lactic acidosis on presentation to hospital. This case demonstrates that a patient can die from paracetamol poisoning despite early and appropriate treatment, and raises the question whether lactic acidosis in a patient following paracetamol overdose should prompt the initiation of NAC treatment while awaiting paracetamol levels.
MeSH term(s)	Acetaminophen/poisoning ; Acetylcysteine/therapeutic use ; Analgesics, Non-Narcotic/poisoning ; Drug Overdose/complications ; Drug Overdose/drug therapy ; Fatal Outcome ; Free Radical Scavengers/therapeutic use ; Humans ; Male ; Middle Aged ; Multiple Organ Failure/chemically induced
Chemical Substances	Analgesics, Non-Narcotic ; Free Radical Scavengers ; Acetaminophen (362O9ITL9D) ; Acetylcysteine (WYQ7N0BPYC)
Language	English
Publishing date	2007-05
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2040124-3
ISSN	1472-0213 ; 1472-0205
ISSN (online)	1472-0213
ISSN	1472-0205
DOI	10.1136/emj.2006.043216
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Zs.A 1941: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito