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Article ; Online: A deep learning-based approach for emotional analysis of sports dance

Qunqun Sun / Xiangjun Wu

PeerJ Computer Science, Vol 9, p e

2023 Volume 1441

Abstract: There is a phenomenon of attaching importance to technique and neglecting emotion in the training of sports dance (SP), which leads to the lack of integration between movement and emotion and seriously affects the training effect. Therefore, this article ...

Abstract	There is a phenomenon of attaching importance to technique and neglecting emotion in the training of sports dance (SP), which leads to the lack of integration between movement and emotion and seriously affects the training effect. Therefore, this article uses the Kinect 3D sensor to collect the video information of SP performers and obtains the pose estimation of SP performers by extracting the key feature points. The Arousal-Valence (AV) emotion model, based on the Fusion Neural Network model (FUSNN), is also combined with theoretical knowledge. It replaces long short term memory (LSTM) with gate recurrent unit (GRU), adds layer-normalization and layer-dropout, and reduces stack levels, and it is used to categorize SP performers’ emotions. The experimental results show that the model proposed in this article can accurately detect the key points in the performance of SP performers’ technical movements and has a high emotional recognition accuracy in the tasks of 4 categories and eight categories, reaching 72.3% and 47.8%, respectively. This study accurately detected the key points of SP performers in the presentation of technical movements and made a major contribution to the emotional recognition and relief of this group in the training process.
Keywords	Sports dance ; Kinect ; AV ; BGRU ; Emotion recognition ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	796
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A deep learning-based approach for emotional analysis of sports dance.

Sun, Qunqun / Wu, Xiangjun

PeerJ. Computer science

2023 Volume 9, Page(s) e1441

Abstract	There is a phenomenon of attaching importance to technique and neglecting emotion in the training of sports dance (SP), which leads to the lack of integration between movement and emotion and seriously affects the training effect. Therefore, this article uses the Kinect 3D sensor to collect the video information of SP performers and obtains the pose estimation of SP performers by extracting the key feature points. The Arousal-Valence (AV) emotion model, based on the Fusion Neural Network model (FUSNN), is also combined with theoretical knowledge. It replaces long short term memory (LSTM) with gate recurrent unit (GRU), adds layer-normalization and layer-dropout, and reduces stack levels, and it is used to categorize SP performers' emotions. The experimental results show that the model proposed in this article can accurately detect the key points in the performance of SP performers' technical movements and has a high emotional recognition accuracy in the tasks of 4 categories and eight categories, reaching 72.3% and 47.8%, respectively. This study accurately detected the key points of SP performers in the presentation of technical movements and made a major contribution to the emotional recognition and relief of this group in the training process.
Language	English
Publishing date	2023-06-27
Publishing country	United States
Document type	Journal Article
ISSN	2376-5992
ISSN (online)	2376-5992
DOI	10.7717/peerj-cs.1441
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Article ; Online: Effects of plant age on antioxidant activity and endogenous hormones in Alpine

Qi, Juan / Wu, Zhaolin / Liu, Yanjun / Meng, Xiangjun

PeerJ

2023 Volume 11, Page(s) e15150

Abstract: ... Elymus ... ...

Abstract	Elymus sibiricus
MeSH term(s)	Antioxidants ; Elymus/physiology ; Tibet ; Plant Growth Regulators ; Abscisic Acid ; Zeatin ; Hormones
Chemical Substances	Antioxidants ; Plant Growth Regulators ; Abscisic Acid (72S9A8J5GW) ; Zeatin (7I6OOJ9GR6) ; Hormones
Language	English
Publishing date	2023-04-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.15150
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Article ; Online: Biological research on the occurrence and development of multiple myeloma and its treatment.

Wu, Yue / Shi, Xiangjun / Yao, Xinchen / Du, Xinru

Immunity, inflammation and disease

2023 Volume 11, Issue 5, Page(s) e850

Abstract: Introduction: To review the pathogenesis and treatment of multiple myeloma (MM). MM is a hematological malignancy with abnormal plasma cell proliferation in bone marrow. Due to the emergence of drug resistance, MM is still an incurable malignancy, which ...

Abstract	Introduction: To review the pathogenesis and treatment of multiple myeloma (MM). MM is a hematological malignancy with abnormal plasma cell proliferation in bone marrow. Due to the emergence of drug resistance, MM is still an incurable malignancy, which requires further exploration of pathogenesis and effective therapeutic targets. Methods: In this paper, the method of literature review is adopted to obtain the information about MM. Based on the literature, comprehensive and systematic review is made. Results: MM is a complex pathophysiological process with great heterogeneity, mainly reflected in genomic instability and bone marrow microenvironment. At present, the treatment of MM has made great progress, proteasome inhibitors and immunomodulatory drugs are widely used in clinic. Allogeneic stem cell transplantation may be the only promising cure for MM, and its high transplant-related mortality limits its clinical application. Conclusions: The future of MM treatment lies in the development of more targeted therapies, novel immunotherapies, and a better understanding of the disease's molecular and genetic basis.
MeSH term(s)	Humans ; Hematopoietic Stem Cell Transplantation ; Immunotherapy ; Multiple Myeloma/therapy ; Multiple Myeloma/drug therapy ; Tumor Microenvironment
Language	English
Publishing date	2023-06-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2740382-8
ISSN	2050-4527 ; 2050-4527
ISSN (online)	2050-4527
ISSN	2050-4527
DOI	10.1002/iid3.850
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Advances in the study of genetic factors and clinical interventions for fertilization failure.

Zhang, Xiangjun / Hu, Congyuan / Wu, Limin

Journal of assisted reproduction and genetics

2023 Volume 40, Issue 8, Page(s) 1787–1805

Abstract: Fertilization failure refers to the failure in the pronucleus formation, evaluating 16-18 h post in vitro fertilization or intracytoplasmic sperm injection. It can be caused by sperm, oocytes, and sperm-oocyte interaction and lead to great financial and ... ...

Abstract	Fertilization failure refers to the failure in the pronucleus formation, evaluating 16-18 h post in vitro fertilization or intracytoplasmic sperm injection. It can be caused by sperm, oocytes, and sperm-oocyte interaction and lead to great financial and physical stress to the patients. Recent advancements in genetics, molecular biology, and clinical-assisted reproductive technology have greatly enhanced research into the causes and treatment of fertilization failure. Here, we review the causes that have been reported to lead to fertilization failure in fertilization processes, including the sperm acrosome reaction, penetration of the cumulus and zona pellucida, recognition and fusion of the sperm and oocyte membranes, oocyte activation, and pronucleus formation. Additionally, we summarize the progress of corresponding treatment methods of fertilization failure. This review will provide the latest research advances in the genetic aspects of fertilization failure and will benefit both researchers and clinical practitioners in reproduction and genetics.
MeSH term(s)	Male ; Animals ; Semen ; Spermatozoa/physiology ; Fertilization in Vitro ; Sperm-Ovum Interactions/genetics ; Acrosome Reaction ; Oocytes/physiology ; Zona Pellucida/physiology ; Fertilization/genetics
Language	English
Publishing date	2023-06-08
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	1112577-9
ISSN	1573-7330 ; 1058-0468
ISSN (online)	1573-7330
ISSN	1058-0468
DOI	10.1007/s10815-023-02810-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of plant age on antioxidant activity and endogenous hormones in Alpine Elymus sibiricus of the Tibetan Plateau

Juan Qi / Zhaolin Wu / Yanjun Liu / Xiangjun Meng

PeerJ, Vol 11, p e

2023 Volume 15150

Abstract: Elymus sibiricus L. is a perennial forage species that has potential to serve as a forage source in livestock grazing systems. However, E. sibiricus has been shown to have a rapid and substantial reduction of aboveground biomass and seed yield after 3 or ...

Abstract	Elymus sibiricus L. is a perennial forage species that has potential to serve as a forage source in livestock grazing systems. However, E. sibiricus has been shown to have a rapid and substantial reduction of aboveground biomass and seed yield after 3 or 4 years and an accelerated aging process. To determine possible aging mechanisms, we planted E. sibiricus seeds in triplicate blocks in 2012, 2015, and 2016, respectively, and harvested samples of leaves and roots at the jointing and heading stages in 2018 and 2019 to determine oxidative indices and endogenous hormones. The fresh aboveground biomass of 4- and 5-year old plants declined by 34.2% and 52.4% respectively compared with 3-year old plants, and the seed yield declined by 12.7% and 34.1%, respectively. The water content in leaves was 51.7%, 43.3%, and 35.6%, and net photosynthesis was 7.73, 6.35, and 2.08 µmol/m2·s in 3-, 4-, and 5-year old plants, respectively. The superoxide anion radical generation rate in leaves and roots did not show any aging pattern. There was a non-significant increase in malondialdehyde concentration with plant age, particularly in leaves and roots at the heading stage in 2019. The superoxide dismutase activity showed a declining trend with age of plant roots at the jointing stage in both 2018 and 2019. The peroxidase activity declined with plant age in both leaves and roots, for example, and the catalase activity in roots 4- and 7-year old plants declined by 13.8% and 0.85%, respectively, compared to 3-year old plants at the heading stage in 2018. Therefore, the reduced capacity of the antioxidant system may lead to oxidative stress during plant aging process. Overall, the concentrations of plant hormones, auxin (IAA), gibberellin (GA), zeatin (ZT), and abscisic acid (ABA) were significantly lower in roots than in leaves. The IAA concentration in leaves and roots exhibited different patterns with plant age. The ZT concentrations in leaves of 3-year old plants was 2.39- and 2.62-fold of those in 4- and 7-year old plants, ...
Keywords	Elymus sibiricus ; Aging ; Growth stage ; Antioxidant system ; Endogenous hormone ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	580
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Neuroprotective effects of galectin‑1 on cerebral ischemia/reperfusion injury by regulating oxidative stress.

Zhao, Jie / Zhu, Rui / He, Feifei / Wu, Miao / Wu, Yufu / Meng, Xiangjun / Liu, Xiaohong

Experimental and therapeutic medicine

2024 Volume 27, Issue 4, Page(s) 154

Abstract: Oxidative stress contributes to the pathology of cerebral ischemia/reperfusion (I/R) injury. Galectin-1 has shown an anti-oxidative stress effect. The present study investigated whether this anti-oxidative stress effect can account for the ... ...

Abstract	Oxidative stress contributes to the pathology of cerebral ischemia/reperfusion (I/R) injury. Galectin-1 has shown an anti-oxidative stress effect. The present study investigated whether this anti-oxidative stress effect can account for the neuroprotective actions of galectin-1 induced by cerebral I/R injury. A cerebral I/R injury model was created in C57Bl/6 mice by transient occlusion of the middle cerebral artery, after which the mice were treated with galectin-1 for 3 days. Infarct volumes were measured. A rotarod test and neurological deficit score assessment was performed to evaluate the neurological deficits. Oxidative stress was evaluated by measuring the levels of reactive oxygen species (ROS) and lipid peroxidation malondialdehyde (MDA), while the anti-oxidative stress status was assessed by measuring molecules such as catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidation enzyme (GSH-Px) in the ischemic cerebral hemisphere of mice. The inflammatory cytokines, including Interleukin 1 (IL-1), IL-6 and tumor necrosis factor alpha (TNF-α) were measured, and the expression of microglia was evaluated by immunohistochemistry in the ischemic cerebral hemisphere of mice. Galectin-1 treatment ameliorated neurological deficits and reduced infarct volumes in the mice model with cerebral I/R injury. Moreover, it was demonstrated that galectin-1 can significantly alleviate cerebral I/R injury in the ischemic cerebral hemisphere by decreasing the production of ROS and MDA, but increasing the production of CAT, SOD and GSH-Px. Galectin-1 treatment decreased microglia expression, and IL-1, IL-6 and TNF-α levels in the ischemic cerebral hemisphere of mice. Galectin-1 could improve the outcome of cerebral I/R injury by alleviating oxidative stress. Moreover, the neuroprotective effect of galectin-1 in cerebral ischemia could be related to its anti-oxidative stress effect.
Language	English
Publishing date	2024-02-20
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2024.12442
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Article ; Online: Correction: Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data.

Fang, Qunying / Qiao, Zonghui / Luo, Lei / Bai, Shun / Chen, Min / Zhang, Xiangjun / Zong, Lu / Tong, Xian-Hong / Wu, Li-Min

Reproductive biology and endocrinology : RB&E

2024 Volume 22, Issue 1, Page(s) 45

Language	English
Publishing date	2024-04-17
Publishing country	England
Document type	Published Erratum
ZDB-ID	2119215-7
ISSN	1477-7827 ; 1477-7827
ISSN (online)	1477-7827
ISSN	1477-7827
DOI	10.1186/s12958-024-01218-6
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Article ; Online: Enhancing THz fingerprint detection by the stretchable substrate with a dielectric metagrating.

Li, Xiangjun / Nie, Lu / Wu, Hang / Zhang, Le / Yan, Dexian

Applied optics

2023 Volume 62, Issue 34, Page(s) 9028–9035

Abstract: The terahertz (THz) wave contains abundant spectrum resources and is still in the early stages of development. It has great application potential in biomedical engineering and public security. However, in these areas there are difficulties to overcome ... ...

Abstract	The terahertz (THz) wave contains abundant spectrum resources and is still in the early stages of development. It has great application potential in biomedical engineering and public security. However, in these areas there are difficulties to overcome like measuring the wide band absorption of a trace mount sample. In this paper, a THz absorption enhancing method is suggested by a multiplexing strategy. By gradually expanding the stretchable substrate of the dielectric metagrating with an oblique THz wave incidence, the resonance peak frequencies can cover the frequency range of 0.48-0.58 THz. Also, the corresponding envelope built by the peaks of the metagrating absorption spectrum with the 0.2 µm
Language	English
Publishing date	2023-12-18
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.501933
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The SP1/SIRT1/ACLY signaling axis mediates fatty acid oxidation in renal ischemia-reperfusion-induced renal fibrosis.

Wu, Huailiang / Wang, Liyan / Kang, Peng / Zhou, Xiangjun / Li, Wei / Xia, Zhongyuan

International immunopharmacology

2024 Volume 132, Page(s) 112002

Abstract: Background: Renal ischemia-reperfusion is the primary cause of acute kidney injury (AKI). Clinically, most patients who experience ischemia-reperfusion injury eventually progress gradually to renal fibrosis and chronic kidney disease (CKD). However, the ...

Abstract	Background: Renal ischemia-reperfusion is the primary cause of acute kidney injury (AKI). Clinically, most patients who experience ischemia-reperfusion injury eventually progress gradually to renal fibrosis and chronic kidney disease (CKD). However, the underlying mechanism for AKI to CKD transition remain absent. Our study demonstrated that the downregulation of sirtuin 1 (Sirt1)-mediated fatty acid oxidation (FAO) facilitates IRI-induced renal fibrosis. Methods: The IRI animal model was established, and ribonucleic acid (RNA) sequencing was used to explore potential differentially expressed genes (DEGs) and pathways. The SIRT1 knockout mice were generated, and a recombinant adeno-associated virus that overexpresses SIRT1 was injected into mice to explore the function of SIRT1 in renal fibrosis induced by renal IRI. In vitro, hypoxia/reoxygenation (H/R) was used to establish the classical model of renal IRI and overexpression or knockdown of SIRT1 to investigate the SIRT1 function through lentiviral plasmids. The underlying molecular mechanism was explored through RNA sequencing, bioinformatics analysis, and chromatin immunoprecipitation assay. Results: RNA sequencing analysis and western blot demonstrated that the expression of SIRT1 was significantly decreased in IRI mice. Overexpression of SIRT1 improved renal function and reduced lipid deposition and renal fibrosis. On the contrary, knockout of SIRT1 aggravated kidney injury and renal fibrosis. RNA sequencing, bioinformatics analysis, and chromatin immunoprecipitation assay mechanistically revealed that SIRT1 impairs the acetylation of histone H3K27 on the promoter region of ACLY, thereby impeding FAO activity and promoting renal fibrosis. Additionally, SP1 regulated FAO by directly modulating SIRT1 expression. Conclusion: Our findings highlight that downregulation of SIRT1-modulated FAO facilitated by the SP1/SIRT1/ACLY axis in the kidney increases IRI, suggesting SIRT1 to be a potential therapeutic target for renal fibrosis induced by renal IRI.
Language	English
Publishing date	2024-04-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2043785-7
ISSN	1878-1705 ; 1567-5769
ISSN (online)	1878-1705
ISSN	1567-5769
DOI	10.1016/j.intimp.2024.112002
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