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Article ; Online: Enhanced linear and symmetric synaptic weight update characteristics in a Pt/p-LiCoO

Jeong, Boyoung / Chung, Peter Hayoung / Han, Jimin / Noh, Taeyun / Yoon, Tae-Sik

2024 Volume 16, Issue 11, Page(s) 5737–5749

Abstract: Artificial synaptic devices have been extensively investigated for neuromorphic computing systems, which require synaptic behaviors mimicking the biological ones. In particular, a highly linear and symmetric weight update with a conductance (or ... ...

Abstract	Artificial synaptic devices have been extensively investigated for neuromorphic computing systems, which require synaptic behaviors mimicking the biological ones. In particular, a highly linear and symmetric weight update with a conductance (or resistance) change for potentiation and depression operation is one of the essential requirements for energy-efficient neuromorphic computing; however, it is not sufficiently met. In this study, a memristor with a Pt/p-LiCoO
Language	English
Publishing date	2024-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr06091h
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Fractional CO

Chung, Youn-Jee / Shim, Suhyun / Kim, Sejin / Cha, Jimin / Song, Jae-Yen / Kim, Min Jeong / Kim, Mee-Ran

Journal of clinical medicine

2023 Volume 12, Issue 11

Abstract: This study evaluates the efficacy and safety of fractional ... ...

Abstract	This study evaluates the efficacy and safety of fractional CO
Language	English
Publishing date	2023-05-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12113679
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Article ; Online: Linear and symmetric synaptic weight update characteristics by controlling filament geometry in oxide/suboxide HfO

Sahu, Dwipak Prasad / Park, Kitae / Chung, Peter Hayoung / Han, Jimin / Yoon, Tae-Sik

Scientific reports

2023 Volume 13, Issue 1, Page(s) 9592

Abstract: Memristive devices have been explored as electronic synaptic devices to mimic biological synapses for developing hardware-based neuromorphic computing systems. However, typical oxide memristive devices suffered from abrupt switching between high and low ... ...

Abstract	Memristive devices have been explored as electronic synaptic devices to mimic biological synapses for developing hardware-based neuromorphic computing systems. However, typical oxide memristive devices suffered from abrupt switching between high and low resistance states, which limits access to achieve various conductance states for analog synaptic devices. Here, we proposed an oxide/suboxide hafnium oxide bilayer memristive device by altering oxygen stoichiometry to demonstrate analog filamentary switching behavior. The bilayer device with Ti/HfO
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-36784-z
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Article ; Online: Non-Targeted Metabolomics Investigation of a Sub-Chronic Variable Stress Model Unveils Sex-Dependent Metabolic Differences Induced by Stress.

Kang, Seulgi / Kim, Woonhee / Nam, Jimin / Li, Ke / Kang, Yua / Bae, Boyeon / Chun, Kwang-Hoon / Chung, ChiHye / Lee, Jeongmi

International journal of molecular sciences

2024 Volume 25, Issue 4

Abstract: Depression is twice as prevalent in women as in men, however, most preclinical studies of depression have used male rodent models. This study aimed to examine how stress affects metabolic profiles depending on sex using a rodent depression model: sub- ... ...

Abstract	Depression is twice as prevalent in women as in men, however, most preclinical studies of depression have used male rodent models. This study aimed to examine how stress affects metabolic profiles depending on sex using a rodent depression model: sub-chronic variable stress (SCVS). The SCVS model of male and female mice was established in discovery and validation sets. The stress-induced behavioral phenotypic changes were similar in both sexes, however, the metabolic profiles of female plasma and brain became substantially different after stress, whereas those of males did not. Four stress-differential plasma metabolites-β-hydroxybutyric acid (BHB), L-serine, glycerol, and myo-inositol-could yield biomarker panels with excellent performance to discern the stressed individuals only for females. Disturbances in BHB, glucose, 1,5-anhydrosorbitol, lactic acid, and several fatty acids in the plasma of stressed females implied a systemic metabolic shift to β-oxidation in females. The plasma levels of BHB and corticosterone only in stressed females were observed not only in SCVS but also in an acute stress model. These results collectively suggest a sex difference in the metabolic responses by stress, possibly involving the energy metabolism shift to β-oxidation and the HPA axis dysregulation in females.
MeSH term(s)	Humans ; Male ; Female ; Mice ; Animals ; Sex Characteristics ; Hypothalamo-Hypophyseal System/metabolism ; Pituitary-Adrenal System/metabolism ; Metabolomics ; Brain/metabolism ; Corticosterone ; Stress, Psychological/metabolism
Chemical Substances	Corticosterone (W980KJ009P)
Language	English
Publishing date	2024-02-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25042443
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Article ; Online: Use of oxygen reserve index during bronchoscopic balloon dilation for subglottic stenosis in a patient with left ventricular assist device implantation -a case report.

Lee, Jimin / Chung, Minwoo / Sung, Eui-Suk / Yoon, Jung-Pil / Yoo, Yeong Min / Bae, Jaesang / Kim, Hee Young

Korean journal of anesthesiology

2023 Volume 77, Issue 2, Page(s) 273–277

Abstract: Background: Monitoring the oxygenation status is crucial during general anesthesia to ensure patient safety. Although noninvasive pulse oximetry is commonly used to monitor percutaneous oxygen saturation (SpO2), it may not accurately reflect changes in ... ...

Abstract	Background: Monitoring the oxygenation status is crucial during general anesthesia to ensure patient safety. Although noninvasive pulse oximetry is commonly used to monitor percutaneous oxygen saturation (SpO2), it may not accurately reflect changes in oxygen partial pressure when the latter is excessively high or low. The oxygen reserve index (ORi) provides real-time information about the oxygen reserve status. Case: We present a case of successful management of subglottic stenosis using balloon bronchoscopy in an infant with a left ventricular assist device implantation under ORi monitoring to predict hypoxemia during the surgical procedure. Conclusions: Utilizing ORi monitoring during anesthesia for procedures involving apnea in critically ill infants can help predict impending desaturation before a drop in SpO2 occurs, allowing anesthesiologists to effectively anticipate and manage the apnea period. Continuous ORi monitoring offers valuable insights during surgical procedures, especially in infants with compromised respiratory and cardiovascular functions.
MeSH term(s)	Infant ; Humans ; Oxygen ; Constriction, Pathologic ; Apnea ; Dilatation ; Heart-Assist Devices ; Anesthesia, General
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-10-06
Publishing country	Korea (South)
Document type	Case Reports
ZDB-ID	2557340-8
ISSN	2005-7563 ; 2005-7563
ISSN (online)	2005-7563
ISSN	2005-7563
DOI	10.4097/kja.23568
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Article ; Online: The Impact of CSR on Corporate Value of Restaurant Businesses Using Triple Bottom Line Theory

Jimin Shim / Joonho Moon / Won Seok Lee / Namho Chung

Sustainability, Vol 13, Iss 4, p

2021 Volume 2131

Abstract: The main goal of this study was to investigate the association between corporate social responsibility (CSR) and the value of restaurant firms by employing triple bottom line theory, a framework for a business model of sustainable development focusing on ...

Abstract	The main goal of this study was to investigate the association between corporate social responsibility (CSR) and the value of restaurant firms by employing triple bottom line theory, a framework for a business model of sustainable development focusing on profit, environment, and people rather than just maximizing profit. Even though triple bottom line has been a common theoretical foundation in the CSR area, there is sparse literature on the theory in the context of CSR in the restaurant domain. Data regarding CSR dimensions and market-to-book value from 32 publicly traded restaurant firms in the US stock market for the period 1999–2012 were gathered, and panel data analysis methods of ordinary least square, one-way fixed effect, and time series feasible generalized least square were employed. The results revealed that economic CSR enhanced restaurant value, whereas environmental CSR diminished the value. The theoretical contribution of this study is that it will broaden the scope of triple bottom line theory. The results of the study will help restaurant administrators determine CSR policy.
Keywords	triple bottom line theory ; social CSR ; economic CSR ; environmental CSR ; restaurant firms ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	650
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Fractional CO 2 Laser Treatment Is Safe and Effective for the Management of Genitourinary Syndrome of Menopause in Korean Women

Youn-Jee Chung / Suhyun Shim / Sejin Kim / Jimin Cha / Jae-Yen Song / Min Jeong Kim / Mee-Ran Kim

Journal of Clinical Medicine, Vol 12, Iss 3679, p

2023 Volume 3679

Abstract: This study evaluates the efficacy and safety of fractional CO 2 lasers for treating genitourinary syndrome of menopause (GSM) in Korean women. The patients received three laser applications at an interval of 4 weeks each. The severity of GSM symptoms was ...

Abstract	This study evaluates the efficacy and safety of fractional CO 2 lasers for treating genitourinary syndrome of menopause (GSM) in Korean women. The patients received three laser applications at an interval of 4 weeks each. The severity of GSM symptoms was assessed using a visual analog scale (VAS) at baseline and at every visit. The objective scale was measured using the vaginal health index score (VHIS) and Vaginal Maturation Index (VMI) after completion of the laser procedure. During each procedure, the patients’ pain in the VAS score was recorded. In the last visit, patients evaluated their satisfaction with the laser therapy using a 5-point Likert scale. Thirty women completed all the study protocols. After two sessions of laser therapy, some GSM symptoms (vaginal dryness and urgency) and VHIS improved significantly. After completion of the treatment, all GSM symptoms improved ( p < 0.05), and the VHIS further increased significantly (VHIS at baseline, 8.86 ± 3.2 vs. V3, 16.83 ± 3.15, p < 0.001). The average satisfaction was 4.3. This study shows that fractional CO 2 laser treatment is effective and safe for Korean women with GSM. Further studies are needed to confirm these results and assess the long-term effects of laser therapy.
Keywords	CO 2 laser ; menopause ; genitourinary syndrome of menopause ; vaginal dryness ; vulvovaginal atrophy ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study.

Lee, Hong Seok / Park, Jimin Clara / Chung, Inkwan / Liu, Junxiu / Lee, Seong-Su / Han, Kyungdo

Diabetes care

2022 Volume 46, Issue 1, Page(s) 92–100

Abstract: Objective: There is limited evidence on the association of sustained low-income status, income changes, and all-cause mortality risk in individuals with type 2 diabetes (T2D).: Research design and methods: Using the Korean Health Insurance Service ... ...

Abstract	Objective: There is limited evidence on the association of sustained low-income status, income changes, and all-cause mortality risk in individuals with type 2 diabetes (T2D). Research design and methods: Using the Korean Health Insurance Service database, we studied 1,923,854 adults with T2D (aged ≥30 years) without cardiovascular disease and cancer, who were enrolled from 2009 through 2012 and followed to the end of 2020 (median 10.8 years of follow-up). We defined income levels based on the amount of health insurance premiums and categorized them into quartiles, the first being the low-income group, and assessed the income status annually in the preceding 5 years. Cox proportional hazards models were used to quantify the association of low-income status and income changes with mortality, with adjustment for sociodemographic factors, comorbidities, and diabetes duration and treatment. Results: Participants who consecutively had low income showed a higher risk of mortality (hazard ratio [HR] 1.19; 95% CI 1.16-1.22), compared with those who had never been in the low-income group. This association was much stronger for consecutive recipients of Medical Aid, reflecting very-low-income status (HR 2.26; 95% CI 2.16-2.36), compared with those who had never been Medical Aid beneficiaries. Sustained low- and very-low-income status was associated with increased risk of mortality, specifically for younger adults (aged <40 years) and males. Those who experienced declines in income between the first (preceding 5 years) and the last (baseline) time points had an increased risk of mortality, regardless of baseline income status. Conclusions: Among Korean adults with T2D, sustained low-income status and declines in income were associated with increased risk of mortality.
MeSH term(s)	Adult ; Male ; Humans ; Diabetes Mellitus, Type 2/epidemiology ; Cohort Studies ; Income ; Socioeconomic Factors ; Poverty ; Cardiovascular Diseases ; Risk Factors
Language	English
Publishing date	2022-11-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	441231-x
ISSN	1935-5548 ; 0149-5992
ISSN (online)	1935-5548
ISSN	0149-5992
DOI	10.2337/dc21-2305
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Zs.A 1434: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Association of Alzheimer's Disease with COVID-19 Susceptibility and Severe Complications: A Nationwide Cohort Study.

Chung, Seok Jong / Chang, Yoonkyung / Jeon, Jimin / Shin, Jae Il / Song, Tae-Jin / Kim, Jinkwon

Journal of Alzheimer's disease : JAD

2022 Volume 87, Issue 2, Page(s) 701–710

Abstract: Background: Identification of patients at high susceptibility and high risk of developing serious complications related to coronavirus disease 2019 (COVID-19) infection is clinically important in the face of the COVID-19 pandemic.: Objective: To ... ...

Abstract	Background: Identification of patients at high susceptibility and high risk of developing serious complications related to coronavirus disease 2019 (COVID-19) infection is clinically important in the face of the COVID-19 pandemic. Objective: To investigate whether patients with Alzheimer's disease (AD) are more susceptible to COVID-19 infection and whether they have a higher risk of developing serious complications. Methods: We retrospectively reviewed the Korean nationwide population-based COVID-19 dataset for participants who underwent real-time reverse transcription polymerase chain reaction assays for COVID-19 between January 1 and June 4, 2020. A 1 : 3 ratio propensity score matching and binary logistic regression analysis were performed to investigate the association between AD and the susceptibility or severe complications (i.e., mechanical ventilation, intensive care unit admission, or death) of COVID-19. Results: Among 195,643 study participants, 5,725 participants had AD and 7,334 participants were diagnosed with COVID-19. The prevalence of participants testing positive for COVID-19 did not differ according to the presence of AD (p = 0.234). Meanwhile, AD was associated with an increased risk of severe COVID-19 complications (OR 2.25 [95% CI 1.54-3.28]). Secondary outcome analyses showed that AD patients had an increased risk for mortality (OR 3.09 [95% CI 2.00-4.78]) but were less likely to receive mechanical ventilation (OR 0.42 [95% CI 0.20-0.87]). Conclusion: AD was not associated with increased susceptibility to COVID-19 infection, but was associated with severe COVID-19 complications, especially with mortality. Early diagnosis and active intervention are necessary for patients with AD suspected COVID-19 infection.
MeSH term(s)	Alzheimer Disease/epidemiology ; COVID-19/complications ; Cohort Studies ; Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2
Language	English
Publishing date	2022-03-11
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-220031
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Article ; Online: Experimental Demonstration of Double Emittance Exchange toward Arbitrary Longitudinal Beam Phase-Space Manipulations.

Seok, Jimin / Ha, Gwanghui / Power, John / Conde, Manoel / Wisniewski, Eric / Liu, Wanming / Doran, Scott / Whiteford, Charles / Chung, Moses

Physical review letters

2022 Volume 129, Issue 22, Page(s) 224801

Abstract: Many of the most significant advances in accelerator science have been due to improvements in our ability to manipulate beam phase space. Despite steady progress in beam phase-space manipulation over the last several decades, future accelerator ... ...

Abstract	Many of the most significant advances in accelerator science have been due to improvements in our ability to manipulate beam phase space. Despite steady progress in beam phase-space manipulation over the last several decades, future accelerator applications continue to outpace the ability to manipulate the phase space. This situation is especially pronounced for longitudinal beam phase-space manipulation, and is now getting increased attention. Herein, we report the first experimental demonstration of the double emittance exchange concept, which allows for the control of the longitudinal phase space using relatively simple transverse manipulation techniques. The double emittance exchange beamline enables extensive longitudinal manipulation, including tunable bunch compression, time-energy correlation control, and nonlinearity correction, in a remarkably flexible manner. The demonstration of this new method opens the door for arbitrary longitudinal beam manipulations capable of responding to the ever increasing demands of future accelerator applications.
Language	English
Publishing date	2022-11-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.129.224801
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