Result 1 - 10 of total 8303
1997
| Keywords | Agribusiness |
|---|---|
| Language | English |
| Publishing country | us |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Physics in medicine and biology
2023
Abstract: Objective: The Jagiellonian PET (J-PET) technology, based on plastic scintillators, has been ... investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation ... to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated ...
| Abstract | Objective: The Jagiellonian PET (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation study of 95 patients who underwent proton therapy at the Cyclotron Centre Bronowice (CCB) in Krakow, Poland.
Approach: Discrepancies between prescribed and delivered treatments were artificially introduced in the simulations by means of shifts in patient positioning and in the Hounsfield unit to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated in an in-room monitoring scenario and a triple-layer, dual-head geometry in an in-beam protocol. The distribution of range shifts in reconstructed PET activity was visualised in the beam's eye view. Linear prediction models were constructed from all patients in the cohort, using the mean shift in reconstructed PET activity as a predictor of the mean proton range deviation.
Main results: Maps of deviations in the range of reconstructed PET distributions showed agreement with those of deviations in dose range in most patients. The linear prediction model showed a good fit, with coefficient of determination r^2 = 0.84 (in-room) and 0.75 (in-beam). Residual standard error was below 1 mm: 0.33 mm (in-room) and 0.23 mm (in-beam).
Significance: The precision of the proposed prediction models shows the sensitivity of the proposed J-PET scanners to shifts in proton range for a wide range of clinical treatment plans. Furthermore, it motivates the use of such models as a tool for predicting proton range deviations and opens up new prospects for investigations into the use of intra-treatment PET images for predicting clinical metrics that aid in the assessment of the quality of delivered treatment.
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| Language | English |
| Publishing date | 2023-06-09 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 208857-5 |
| ISSN | 1361-6560 ; 0031-9155 |
| ISSN (online) | 1361-6560 |
| ISSN | 0031-9155 |
| DOI | 10.1088/1361-6560/acdd4c |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 199: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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1983
Abstract: ... Ramil; Petersen, Nikolai P; Smith, Charles C; Tucker, Peter; Hs?, Kenneth J (1984): Late Cretaceous ... Drilling Project Leg 73. In: Hs?, K.H., LaBrecque, J.L., et al. (eds.), Initial Reports of the Deep Sea ...
| Abstract | DSDP Leg 73 sediment cores allow direct calibrations of magnetostratigraphy and biostratigraphy for much of the latest Cretaceous to Cenozoic in the mid-latitude South Atlantic Ocean. A complete record of the Cenozoic was not obtained, however, because strong dissolution, poor core recovery and intense core disturbance have masked the biostratigraphy or magnetostratigraphy over some intervals of all recovered sections. DSDP Leg 73 results show the following correlations: Early/middle Miocene in Chron 16 Oligocene/Miocene within Subchron C6CN Eocene/Oligocene within Subchron C13R Middle/late Eocene top of Chron C17 Early/late Paleocene top of Subchron C27N Cretaceous/Tertiary within Subchron C29R REFERENCE: Poore, Richard Z; Tauxe, Lisa; Percival, Stephen F Jr; LaBrecque, John L; Wright, Ramil; Petersen, Nikolai P; Smith, Charles C; Tucker, Peter; Hs?, Kenneth J (1984): Late Cretaceous-Cenozoic magnetostratigraphic and biostratigraphic correlations for the South Atlantic Ocean, Deep-Sea Drilling Project Leg 73. In: Hs?, K.H., LaBrecque, J.L., et al. (eds.), Initial Reports of the Deep Sea Drilling Project, Washington (U.S. Government Print Office), 73, 645-655 |
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| Language | English |
| Dates of publication | 1983-9999 |
| Size | Online-Ressource |
| Publisher | PANGAEA - Data Publisher for Earth & Environmental Science |
| Publishing place | Bremen/Bremerhaven |
| Document type | Book ; Online |
| Note | This dataset is cited by doi:10.2973/dsdp.proc.73.126.1984 ; This dataset is supplement to doi:10.1016/0031-0182(83)90041-X |
| DOI | 10.1594/PANGAEA.702054 |
| Database | Library catalogue of the German National Library of Science and Technology (TIB), Hannover |
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2024 Volume 19, Issue 4, Page(s) e0301578
Abstract: Background: Although most of the livelihood programmes target women, those that involve women and men have been evaluated as though men and women were a single homogenous population, with a mere inclusion of gender as an explanatory variable. This study ...
| Abstract | Background: Although most of the livelihood programmes target women, those that involve women and men have been evaluated as though men and women were a single homogenous population, with a mere inclusion of gender as an explanatory variable. This study evaluated the impact of WORTH Yetu (an economic empowerment intervention to improve livelihood outcomes) on household hunger, and household socioeconomic status (SES) among caregivers (both women and men) of orphaned and vulnerable children (OVC) in Tanzania. The study hypothesized that women and men respond to livelihood interventions differently, hence a need for gender-disaggregated impact evaluation of such interventions. Methods: This is a secondary analysis of longitudinal data, involving caregivers' baseline (2016-2019) and follow-up (2019-2020) data from the USAID Kizazi Kipya project in 25 regions of Tanzania. Two dependent variables (ie, outcomes) were assessed; household hunger which was measured using the Household Hunger Scale (HHS), and Socioeconomic Status (SES) using the Principal Component Analysis (PCA). WORTH Yetu, a livelihood intervention implemented by the USAID Kizazi Kipya project was the main independent variable whose impact on the two outcomes was evaluated using multivariate analysis with a multilevel mixed-effects, ordinal logistic regression model with difference-in-differences (DiD) estimator for impact estimation. Results: The analysis was based on 497,293 observations from 249,655 caregivers of OVC at baseline, and 247,638 of them at the follow-up survey. In both surveys, 70% were women and 30% were men. Their mean age was 49.3 (±14.5) years at baseline and 52.7 (±14.8) years at the follow-up survey. Caregivers' membership in WORTH Yetu was 10.1% at the follow-up. After adjusting for important confounders there was a significant decline in the severity of household hunger by 46.4% among WORTH Yetu members at the follow-up compared to the situation at the baseline (adjusted Odds Ratio (aOR) = 0.536, 95% Confidence Interval (CI) [0.521, 0.553]). The decline was 45.7% among women (aOR = 0.543 [0.524, 0.563]) and 47.5% among men (aOR = 0.525 [0.497, 0.556]). Regarding SES, WORTH Yetu members were 15.9% more likely to be in higher wealth quintiles at the follow-up compared to the situation at the baseline (aOR = 1.159 [1.128, 1.190]). This impact was 20.8% among women (aOR = 1.208 [1.170, 1.247]) and 4.6% among men (aOR = 1.046 [0.995, 1.101]). Conclusion: WORTH Yetu was associated with a significant reduction in household hunger, and a significant increase in household SES among OVC caregivers in Tanzania within an average follow-up period of 1.6 years. The estimated impacts differed significantly by gender, suggesting that women and men responded to the WORTH Yetu intervention differently. This implied that the design, delivery, and evaluation of such programmes should happen in a gender responsive manner, recognising that women and men are not the same with respect to the programmes. |
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| MeSH term(s) | Child ; Male ; Humans ; Female ; Middle Aged ; Caregivers ; Logistic Models ; Tanzania/epidemiology ; Hunger ; Social Class ; Surveys and Questionnaires |
| Language | English |
| Publishing date | 2024-04-16 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2267670-3 |
| ISSN | 1932-6203 ; 1932-6203 |
| ISSN (online) | 1932-6203 |
| ISSN | 1932-6203 |
| DOI | 10.1371/journal.pone.0301578 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2012
| Author's details | ed. by Jason Lee |
|---|---|
| Keywords | Compulsive behavior/Social aspects |
| Subject code | 616.85/84 |
| Language | English |
| Size | XX, 314 S. : Ill. |
| Publisher | Cambria Press |
| Publishing place | Amherst, NY |
| Publishing country | United States |
| Document type | Book |
| Note | Includes bibliographical references and index |
| HBZ-ID | HT017230747 |
| ISBN | 978-1-60497-799-8 ; 1-60497-799-X |
| Database | Catalogue ZB MED Medicine, Health |
| Shelf mark | Loan status | Location |
|---|---|---|
| 2012 A 3262 | order for loan | Magazin |
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Journal of cardiothoracic and vascular anesthesia
2023 Volume 37, Issue 9, Page(s) 1533–1536
| MeSH term(s) | Humans ; Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Anesthesiologists ; Atrial Septum/diagnostic imaging ; Echocardiography, Transesophageal |
|---|---|
| Language | English |
| Publishing date | 2023-05-12 |
| Publishing country | United States |
| Document type | Editorial ; Comment |
| ZDB-ID | 1067317-9 |
| ISSN | 1532-8422 ; 1053-0770 |
| ISSN (online) | 1532-8422 |
| ISSN | 1053-0770 |
| DOI | 10.1053/j.jvca.2023.05.015 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2203: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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| Zs.MO 31: Show issues |
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Journal of cardiothoracic and vascular anesthesia
2023 Volume 37, Issue 9, Page(s) 1529–1532
| MeSH term(s) | Humans ; Anesthesiologists ; Echocardiography, Transesophageal ; Pulmonary Valve ; Cardiac Catheterization ; Tricuspid Valve Insufficiency/surgery ; Heart Valve Prosthesis Implantation ; Treatment Outcome |
|---|---|
| Language | English |
| Publishing date | 2023-05-11 |
| Publishing country | United States |
| Document type | Editorial ; Comment |
| ZDB-ID | 1067317-9 |
| ISSN | 1532-8422 ; 1053-0770 |
| ISSN (online) | 1532-8422 |
| ISSN | 1053-0770 |
| DOI | 10.1053/j.jvca.2023.05.016 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2203: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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| Zs.MO 31: Show issues |
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2024 Volume 64, Issue 4, Page(s) 333–341
Abstract: Objective: To provide a position statement update from The American Headache Society specifically regarding therapies targeting calcitonin gene-related peptide (CGRP) for the prevention of migraine.: Background: All migraine preventive therapies ... ...
| Abstract | Objective: To provide a position statement update from The American Headache Society specifically regarding therapies targeting calcitonin gene-related peptide (CGRP) for the prevention of migraine. Background: All migraine preventive therapies previously considered to be first-line treatments were developed for other indications and adopted later for migraine. Adherence to these therapies is often poor due to issues with efficacy and tolerability. Multiple new migraine-specific therapies have been developed based on a broad foundation of pre-clinical and clinical evidence showing that CGRP plays a key role in the pathogenesis of migraine. These CGRP-targeting therapies have had a transformational impact on the management of migraine but are still not widely considered to be first-line approaches. Methods: Evidence regarding migraine preventive therapies including primary and secondary endpoints from randomized placebo-controlled clinical trials, post hoc analyses and open-label extensions of these trials, and prospective and retrospective observational studies were collected from a variety of sources including PubMed, Google Scholar, and ClinicalTrials.gov. The results and conclusions based upon these results were reviewed and discussed by the Board of Directors of The American Headache Society to confirm consistency with clinical experience and to achieve consensus. Results: The evidence for the efficacy, tolerability, and safety of CGRP-targeting migraine preventive therapies (the monoclonal antibodies: erenumab, fremanezumab, galcanezumab, and eptinezumab, and the gepants: rimegepant and atogepant) is substantial, and vastly exceeds that for any other preventive treatment approach. The evidence remains consistent across different individual CGRP-targeting treatments and is corroborated by extensive "real-world" clinical experience. The data indicates that the efficacy and tolerability of CGRP-targeting therapies are equal to or greater than those of previous first-line therapies and that serious adverse events associated with CGRP-targeting therapies are rare. Conclusion: The CGRP-targeting therapies should be considered as a first-line approach for migraine prevention along with previous first-line treatments without a requirement for prior failure of other classes of migraine preventive treatment. |
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| MeSH term(s) | Migraine Disorders/prevention & control ; Migraine Disorders/drug therapy ; Humans ; Calcitonin Gene-Related Peptide/antagonists & inhibitors ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Societies, Medical/standards ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; United States ; Antibodies, Monoclonal, Humanized/pharmacology |
| Chemical Substances | Calcitonin Gene-Related Peptide (JHB2QIZ69Z) ; Calcitonin Gene-Related Peptide Receptor Antagonists ; Antibodies, Monoclonal ; erenumab (I5I8VB78VT) ; Antibodies, Monoclonal, Humanized ; fremanezumab ; eptinezumab (8202AY8I7H) |
| Language | English |
| Publishing date | 2024-03-11 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 410130-3 |
| ISSN | 1526-4610 ; 0017-8748 |
| ISSN (online) | 1526-4610 |
| ISSN | 0017-8748 |
| DOI | 10.1111/head.14692 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.B 539: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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Annals of surgery open : perspectives of surgical history, education, and clinical approaches
2022 Volume 3, Issue 3, Page(s) e186
| Language | English |
|---|---|
| Publishing date | 2022-07-21 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2691-3593 |
| ISSN (online) | 2691-3593 |
| DOI | 10.1097/AS9.0000000000000186 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Philosophical transactions of the Royal Society of London. Series B, Biological sciences
2023 Volume 379, Issue 1893, Page(s) 20220257
Abstract: We derive and analyse a model with unusual features characterizing human activities over the long-run. First, human population dynamics draw heavily on consumer-resource modelling in ecology in that humans must consume biological resources to produce new ...
| Abstract | We derive and analyse a model with unusual features characterizing human activities over the long-run. First, human population dynamics draw heavily on consumer-resource modelling in ecology in that humans must consume biological resources to produce new humans. Second, the model also draws heavily from economic growth theory in that humans do not simply consume biological resources; they also produce the resources they consume. Finally, humans use two types of technology. Consumption technology affects the rate at which humans can extract resources. Production technology controls how effectively humans convert labour into new resources. The dynamics of both types of technology are subject to cumulative cultural evolutionary processes that allow both technological progress and regress. The resulting model exhibits a wide range of dynamical regimes. That said, the system is routinely sensitive to initial conditions, with wildly different outcomes given the same parameter values. Moreover, the system exhibits a basic fragility in the sense that human activities often lead to the endogenous extinction of the human species. This can happen gently, or it can follow periods of explosive human activity with super-exponential growth that ends in collapse. This article is part of the theme issue 'Evolution and sustainability: gathering the strands for an Anthropocene synthesis'. |
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| MeSH term(s) | Humans ; Cultural Evolution ; Ecology ; Technology ; Population Dynamics ; Economic Development |
| Language | English |
| Publishing date | 2023-11-13 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 208382-6 |
| ISSN | 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436 |
| ISSN (online) | 1471-2970 |
| ISSN | 0080-4622 ; 0264-3839 ; 0962-8436 |
| DOI | 10.1098/rstb.2022.0257 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Einzelsignatur: Show issues |
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