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Article ; Online: Characterization of key odorants in Langyatai Baijiu with Jian flavour by sensory-directed analysis.

Du, Jingyi / Li, Yueming / Xu, Jianchun / Huang, Mingquan / Wang, Juan / Chao, Jinfu / Wu, Jihong / Sun, Huibin / Ding, Haimei / Ye, Hong

Food chemistry

2021 Volume 352, Page(s) 129363

Abstract: ... Baijiu with Jian flavour (LBJF) using sensory omics analysis (SOA). A total of 56 odorants were screened ... This study uncovers the characteristics of Jian flavour Baijiu (JFB) and provides a scientific basis ...

Abstract	A study was carried out to determine systematically the key aroma-active compounds of Langyatai Baijiu with Jian flavour (LBJF) using sensory omics analysis (SOA). A total of 56 odorants were screened out using gas chromatography-olfactometry-mass spectrometry (GC-O-MS)/Osme analysis. Among them, 15 aroma-active components were first identified. After quantitation, 30 odorants had odour activity values (OAVs) > 1.0 in LBJF. Recombinant and omission experiments proved that the esters, alcohols, acids, especially ethyl hexanoate, γ-nonalactone, and dimethyl trisulfide, were critical to the flavour of LBJF. The basic and commercial liquors had obvious differences in the skeleton compositions of esters and acids. This study uncovers the characteristics of Jian flavour Baijiu (JFB) and provides a scientific basis for the quality control of JFB, which is helpful for the development of Chinese Baijiu flavour styles.
MeSH term(s)	Alcoholic Beverages/analysis ; Food Analysis/methods ; Gas Chromatography-Mass Spectrometry ; Humans ; Odorants/analysis ; Olfactometry ; Taste ; Volatile Organic Compounds/analysis
Chemical Substances	Volatile Organic Compounds
Language	English
Publishing date	2021-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2021.129363
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Article ; Online: The Combination of Individual Herb of Mi-Jian-Chang-Pu Formula Exerts a Synergistic Effect in the Treatment of Ischemic Stroke in Rats.

Lu, Fangfang / Su, Xiaojuan / Liu, Jingjing / Zong, Rong / Ding, Shuqin / Yang, Lingling / Liu, Jing / Wilson, Gidion / Li, Liuyan / Yang, Youyue / Wang, Xiaoying / Wang, Weibiao / Ma, Xueqin

Oxidative medicine and cellular longevity

2022 Volume 2022, Page(s) 9365760

Abstract: Mi-Jian-Chang-Pu formula (MJCPF), composed of ...

Abstract	Mi-Jian-Chang-Pu formula (MJCPF), composed of
MeSH term(s)	Animals ; Male ; Rats ; Brain Ischemia/drug therapy ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/metabolism ; Ischemic Stroke ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Rats, Sprague-Dawley ; Stroke/drug therapy
Chemical Substances	asarone ; crocin (877GWI46C2) ; Neuroprotective Agents
Language	English
Publishing date	2022-10-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2455981-7
ISSN	1942-0994 ; 1942-0994
ISSN (online)	1942-0994
ISSN	1942-0994
DOI	10.1155/2022/9365760
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Article ; Online: Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian)

Chaonan Zhang / Qiujie Wang / Zhiheng Zuo / Jianhua Ding / Guohuan Xu / Jixing Zou

Frontiers in Environmental Science, Vol

2021 Volume 9

Abstract: ... used Jian carp (Cyprinus carpio var. Jian) as the model organism to explore the bioaccumulation and ... that TC-MP combined exposure could reduce oxidative damage to Jian carps compared to MP exposure alone ...

Abstract	Microplastics (MPs) and tetracycline (TC) are severe emerging pollutants in the aquatic environment. But there is a lack of research to investigate the interactive effects of MPs and TC in vivo. This study used Jian carp (Cyprinus carpio var. Jian) as the model organism to explore the bioaccumulation and biochemical status when exposed to MPs and TC, alone and combined. The accumulation of TC and MPs in intestine, variation of enzyme activities in intestine, and expression of immune-related genes in muscle were evaluated. Our results found the bioaccumulation of MPs was not affected by TC, but the presence of MPs would change the content of TC within 48 h. The superoxide dismutase (SOD) and lactate dehydrogenase (LDH) activity showed that TC-MP combined exposure could reduce oxidative damage to Jian carps compared to MP exposure alone. The integrated biomarker response (IBR) index showed that SOD activity was sensitive to TC-MP exposure. In addition, co-exposure to MPs and TC could alleviate the overexpression of interleukin 1 beta (IL-1β), interleukin 10 (IL-10), transforming growth factor beta (TGF-β), and toll like receptor 2 (TLR-2) induced by TC in muscles. TLR-2 gene has the potential to be the candidate gene reflecting the injury of TC exposure. In conclusion, it is inferred that co-exposure may reduce the toxicity of individual exposure in the living organisms. This study provides essential information for the risk assessment of pollution with MPs and TC, individually and combined, as well as a foundation to investigate the interactive effects of MPs and antibiotics on aquatic ecosystems.
Keywords	microplastics ; tetracycline ; Jian carp ; bioaccumulation ; antioxidant response ; Environmental sciences ; GE1-350
Subject code	150
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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Article ; Online: Comprehensive Trait Evaluation of Five Different Flue-cured Tobacco Genotypes in Ji'an Tobacco Production Area of Jiangxi

Yongliang DING / Renxiao CHEN / Kuanxin HE / Qiming ZHANG / Hongxia LI / Hao XIA / Jiayu CHEN / Jumin YUAN

Guangdong nongye kexue, Vol 49, Iss 8, Pp 29-

2022 Volume 37

Abstract: ... with high quality adapted to ecological conditions in Ji'an tobacco production area.【Method】Five flue-cured ...

Abstract	【Objective】The study was carried out to screen new varieties (lines) of flue-cured tobacco with high quality adapted to ecological conditions in Ji'an tobacco production area.【Method】Five flue-cured tobacco varieties (lines) including CC400, PVH2233, PVH2343, 1604 and Xiangyan 7 were introduced from the imported varieties and domestic self-bred varieties, and the main conventional varieties Yunyan 87 and K326 were used as control varieties. A community comparative trial was conducted for two consecutive years from 2019 to 2020. The growth period, agronomic traits, disease resistance, economic characters, appearance quality, chemical composition and sensory quality of each variety (line) were analyzed.【Result】The Xiangyan 7, which showed a good balance between quality and benefit, had better color and oil content. The output and yield of Xiangyan 7 were higher than those of Yunyan 87 by 305.85 kg/hm2 and 4 837.95 Yuan/hm2 respectively. The sensory quality was obviously better than the main variety Yunyan 87. However, attention should be paid to the prevention and control of common mosaic disease in field at early stage. The PVH2233 with good interannual stability and medium sensory quality had 3-4 pieces of leaves more than the control, and the vigorous growing period was 5-7 days longer than that of the control. It was necessary to strengthen the researches on supporting cultivation techniques. The 1604 had the advantages of early growth and rapid development, largest pitch and lumbar leaf area, better appearance quality and economic character, and better sensory quality than Yunyan 87. The CC400 was similar to K326 in field growth and had better leaf opening, but the occurrence of bacterial wilt was relatively severe and the economic character was not prominent. The PVH2343 had thicker leaves, but the incidence of climatic spot disease was more severe, and the sensory quality was slightly poor.【Conclusion】The comprehensive performance of Xiangyan 7, PVH2233 and 1604 was better, which could be further verified ...
Keywords	flue-cured tobacco ; new variety ; introduced variety ; screening ; adaptability ; ji'an tobacco area ; Agriculture ; S
Subject code	580
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Guangdong Academy of Agricultural Sciences
Document type	Article ; Online
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Article ; Online: Effects of Rhizoma Alismatis extract on biochemical indices and adipose gene expression in oleic acid-induced hepatocyte injury in Jian carp (Cyprinus carpio var. Jian).

Du, Jinliang / Jia, Rui / Cao, Li-Ping / Ding, Weidong / Xu, Pao / Yin, Guojun

Fish physiology and biochemistry

2018 Volume 44, Issue 3, Page(s) 747–768

Abstract: ... extract (RAE) in Jian carp using this model. Primary hepatocytes from Jian carp were isolated and purified ...

Abstract	Fatty liver is an increasingly serious disease of fish in aquaculture. However, the mechanisms responsible for the occurrence of fatty liver remain unclear, and no effective methods for the prevention and treatment of this disease have yet been found. In the present study, we aimed to develop an in vitro model of hepatocyte injury using oleic acid as hepatotoxicant and evaluate the protective effects of Rhizoma Alismatis extract (RAE) in Jian carp using this model. Primary hepatocytes from Jian carp were isolated and purified and cultured in vitro. The result indicated that 0.4 mmol L
MeSH term(s)	Alisma ; Animals ; Carps/genetics ; Carps/metabolism ; Cell Survival/drug effects ; Cells, Cultured ; Cytochrome P-450 Enzyme System/metabolism ; Fatty Liver/metabolism ; Fatty Liver/veterinary ; Fish Diseases/metabolism ; Gene Expression/drug effects ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/pathology ; L-Lactate Dehydrogenase/metabolism ; Lipid Metabolism/drug effects ; NF-kappa B/metabolism ; Oleic Acid ; Plant Extracts/pharmacology ; Rhizome ; Transaminases/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; gamma-Glutamyltransferase/metabolism
Chemical Substances	NF-kappa B ; Plant Extracts ; Tumor Necrosis Factor-alpha ; Oleic Acid (2UMI9U37CP) ; Cytochrome P-450 Enzyme System (9035-51-2) ; L-Lactate Dehydrogenase (EC 1.1.1.27) ; gamma-Glutamyltransferase (EC 2.3.2.2) ; Transaminases (EC 2.6.1.-)
Language	English
Publishing date	2018-03-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	292907-7
ISSN	1573-5168 ; 0920-1742
ISSN (online)	1573-5168
ISSN	0920-1742
DOI	10.1007/s10695-017-0428-2
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Article ; Online: Identification and characterization of a LTR retrotransposon from the genome of Cyprinus carpio var. Jian.

Cao, Liping / Yin, Guojun / Cao, Zheming / Bing, Xuwen / Ding, Weidong

Genetica

2016 Volume 144, Issue 3, Page(s) 325–333

Abstract: A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp ... Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian ... in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA of the JRE ...

Abstract	A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp (Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian retrotransposon). The full-length JRE retrotransposon is 5126 bp, which includes two long terminal repeats of 470 bp at the 5' end and 453 bp at the 3' end, and two open reading frames between them: 4203 bp encoding the group-specific antigen (GAG) and polyprotein (POL). The pol gene has a typical Ty3/gypsy retrotransposon structure, and the gene order is protease, reverse transcriptase, RNase H, and integrase (PR-RT-RH-IN). A phylogenetic analysis of the pol gene showed that it has similarities of 40.7, 40, and 32.8 %, to retrotransposons of Azumapecten farreri, Mizuhopecten yessoensis, and Xiphophorus maculatus, respectively. Therefore, JRE might belong to the JULE retrotransposon family. The copy number of the JRE transposon in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA of the JRE retrotransposon is expressed in five Jian carp tissues, the liver, kidney, blood, muscle, and gonad, and slightly higher in the kidney and liver than in the other tissues.
MeSH term(s)	Animals ; Carps/classification ; Carps/genetics ; Chromosome Mapping ; Computational Biology ; Gene Dosage ; Gene Expression ; Genome ; In Situ Hybridization, Fluorescence ; Open Reading Frames ; Organ Specificity/genetics ; Phylogeny ; Retroelements ; Terminal Repeat Sequences ; Transcription, Genetic
Chemical Substances	Retroelements
Language	English
Publishing date	2016-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2165-9
ISSN	1573-6857 ; 0016-6707
ISSN (online)	1573-6857
ISSN	0016-6707
DOI	10.1007/s10709-016-9901-6
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Article ; Online: A traditional Chinese medicine compound (Jian Er) for presbycusis in a mouse model: Reduction of apoptosis and protection of cochlear sensorineural cells and hearing.

Xuan, Yi / Ding, Dalian / Xuan, Weijun / Huang, Liyi / Tang, Junbo / Wei, Yulong / Chen, Sizhong / Hamblin, Michael R

International journal of herbal medicine

2019 Volume 6, Issue 6, Page(s) 127–135

Abstract: ... Jian Er" in a mouse model of prebycusis. ...

Abstract	Age-related hearing loss (AHL) or presbycusis is steadily increasing due to the overall aging of the Chinese population. Traditional Chinese medicine (TCM) has long been used to prevent and treat deafness, but its effectiveness and mechanism of action are still uncertain. The present study tested a TCM preparation called "Jian Er" in a mouse model of prebycusis.
Language	English
Publishing date	2019-12-04
Publishing country	India
Document type	Journal Article
ZDB-ID	2732957-4
ISSN	2321-2187 ; 2321-2187
ISSN (online)	2321-2187
ISSN	2321-2187
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Article ; Online: Effects of curcumin on antioxidative activities and cytokine production in Jian carp (Cyprinus carpio var. Jian) with CCl4-induced liver damage.

Cao, Liping / Ding, Weidong / Du, Jingliang / Jia, Rui / Liu, Yingjuan / Zhao, Caiyuan / Shen, Yujin / Yin, Guojun

Fish & shellfish immunology

2015 Volume 43, Issue 1, Page(s) 150–157

Abstract: We investigated the protective effects of curcumin on liver-damaged Cyprinus carpio var. Jian (Jian ... that curcumin reduces CCl(4)-induced liver damage in Jian carp by upregulating antioxidative activities and ...

Abstract	We investigated the protective effects of curcumin on liver-damaged Cyprinus carpio var. Jian (Jian carp). The carp were fed 0.1%, 0.5%, or 1.0% curcumin for 60 days, then injected intraperitoneally with 30% carbon tetrachloride solution. Liver and blood samples were collected to measure the liver index, serum- and liver-associated enzymes, liver histology, nuclear factor-κB (NF-κB)/c-Rel, interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and IL-12 mRNA expression, and the level of NF-κB/c-Rel protein in the liver, and for a comet assay. We found that 0.5% and 1.0% curcumin significantly reduced the CCl(4)-induced increase in the liver index. The comet assay showed that the tail moment, olive tail moment, tail length, and tail DNA% improved in fish pretreated with 0.5 or 1.0% curcumin. CCl(4)-induced histological changes, including extensive hepatocyte degeneration, indistinct cell borders, nuclear condensation, and karyolysis were clearly reduced after treatment with 0.5% and 1.0% curcumin. Moreover, 0.5% and 1.0% curcumin significantly inhibited the CCl(4)-induced increase in serum glutamic oxaloacetic transaminase and promoted the restoration of superoxide dismutase in the liver; 1.0% curcumin significantly reduced serum glutamic pyruvic transaminase and lactate dehydrogenase and hepatic malondialdehyde, but significantly increased the total antioxidant capacity and glutathione levels in the liver. The CCl(4)-induced upregulation of NF-κB/c-Rel, IL-1β, and TNF-α mRNAs and NF-κB/c-Rel protein levels was inhibited by 0.5% and 1.0% curcumin, and IL-12 mRNA was reduced by all three doses of curcumin. The effects of curcumin on the liver index, enzymes, histological changes, and cytokines were dose-dependent. Our results indicate that curcumin reduces CCl(4)-induced liver damage in Jian carp by upregulating antioxidative activities and inhibiting NF-κB, IL-1β, TNF-α, and IL-12 expression.
MeSH term(s)	Animals ; Carbon Tetrachloride/toxicity ; Carps/genetics ; Carps/metabolism ; Curcumin/pharmacology ; Cytokines/genetics ; Cytokines/metabolism ; Fish Proteins/genetics ; Fish Proteins/metabolism ; Gene Expression Regulation/drug effects ; Liver/drug effects ; Liver/enzymology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Cytokines ; Fish Proteins ; RNA, Messenger ; Tumor Necrosis Factor-alpha ; Carbon Tetrachloride (CL2T97X0V0) ; Curcumin (IT942ZTH98)
Language	English
Publishing date	2015-03
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	1067738-0
ISSN	1095-9947 ; 1050-4648
ISSN (online)	1095-9947
ISSN	1050-4648
DOI	10.1016/j.fsi.2014.12.025
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Article: Effects of Rhizoma Alismatis extract on biochemical indices and adipose gene expression in oleic acid-induced hepatocyte injury in Jian carp (Cyprinus carpio var. Jian)

Du, Jinliang / Guojun Yin / Li-ping Cao / Pao Xu / Rui Jia / Weidong Ding

Fish physiology and biochemistry. 2018 June, v. 44, no. 3

2018

Abstract: ... extract (RAE) in Jian carp using this model. Primary hepatocytes from Jian carp were isolated and purified ... hepatocyte injury in Jian carp. Further in vivo studies are needed to provide more evidence for the use ...

Abstract	Fatty liver is an increasingly serious disease of fish in aquaculture. However, the mechanisms responsible for the occurrence of fatty liver remain unclear, and no effective methods for the prevention and treatment of this disease have yet been found. In the present study, we aimed to develop an in vitro model of hepatocyte injury using oleic acid as hepatotoxicant and evaluate the protective effects of Rhizoma Alismatis extract (RAE) in Jian carp using this model. Primary hepatocytes from Jian carp were isolated and purified and cultured in vitro. The result indicated that 0.4 mmol L−1 oleic acid and 48 h could be the optimal conditions to induce hepatocyte injury model in cultured hepatocytes. Hepatocytes were exposed to oleic acid, followed by the addition of RAE at 0, 1, 5, 10, 20, or 50 μg mL−1. The hepatocytes and supernatant were then analyzed. RAE suppressed oleic acid-induced elevations in aspartate aminotransferase, alanine aminotransferase, triglycerides, total cholesterol, lactate dehydrogenase, alkaline phosphatase, cholinesterase, malondialdehyde, γ-glutamyl transferase, cytochrome P450 1A, cytochrome P450 2E1, liver-type fatty acid binding protein, free fatty acid, fatty acid synthetase, and tumor necrosis factor-α (P < 0.01 or P < 0.05); reduced protein levels of cytochrome P450 1A, nuclear factor (NF)-κB p65, and NF-κB c-Rel; and inhibited cytochrome P4503A, NF-κB c-Rel, nuclear factor erythroid-related factor 2, peroxisome proliferator-activated receptor-α, and cytochrome P4501A mRNA levels. In conclusion, RAE exhibited a protective effect against hepatocyte injury in Jian carp. Further in vivo studies are needed to provide more evidence for the use of RAE as a hepatoprotective agent for the treatment of hepatocyte injury.
Keywords	alanine transaminase ; alkaline phosphatase ; aquaculture ; aspartate transaminase ; carp ; cholesterol ; cholinesterase ; Cyprinus carpio ; cytochrome P-450 ; fatty acid-binding proteins ; fatty liver ; fatty-acid synthase ; free fatty acids ; gamma-glutamyltransferase ; gene expression ; hepatocytes ; in vivo studies ; lactate dehydrogenase ; malondialdehyde ; messenger RNA ; models ; oleic acid ; protective effect ; protein content ; transcription factor NF-kappa B ; triacylglycerols ; tumor necrosis factor-alpha
Language	English
Dates of publication	2018-06
Size	p. 747-768.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	292907-7
ISSN	1573-5168 ; 0920-1742
ISSN (online)	1573-5168
ISSN	0920-1742
DOI	10.1007/s10695-017-0428-2
Database	NAL-Catalogue (AGRICOLA)

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Article: Identification and characterization of a LTR retrotransposon from the genome of Cyprinus carpio var. Jian

Cao, Liping / Guojun Yin / Zheming Cao / Xuwen Bing / Weidong Ding

Genetica. 2016 June, v. 144, no. 3

2016

Abstract: A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp ... Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian ... transposon in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA ...

Abstract	A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp (Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian retrotransposon). The full-length JRE retrotransposon is 5126Â bp, which includes two long terminal repeats of 470Â bp at the 5â² end and 453Â bp at the 3â² end, and two open reading frames between them: 4203Â bp encoding the group-specific antigen (GAG) and polyprotein (POL). The pol gene has a typical Ty3/gypsy retrotransposon structure, and the gene order is protease, reverse transcriptase, RNase H, and integrase (PRâRTâRHâIN). A phylogenetic analysis of the pol gene showed that it has similarities of 40.7, 40, and 32.8Â %, to retrotransposons of Azumapecten farreri, Mizuhopecten yessoensis, and Xiphophorus maculatus, respectively. Therefore, JRE might belong to the JULE retrotransposon family. The copy number of the JRE transposon in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA of the JRE retrotransposon is expressed in five Jian carp tissues, the liver, kidney, blood, muscle, and gonad, and slightly higher in the kidney and liver than in the other tissues.
Keywords	Azumapecten farreri ; Cyprinus carpio ; Mizuhopecten yessoensis ; RNA-directed DNA polymerase ; Xiphophorus maculatus ; antigens ; blood ; carp ; genes ; kidneys ; liver ; messenger RNA ; muscles ; open reading frames ; phylogeny ; polyproteins ; proteinases ; quantitative polymerase chain reaction ; retrotransposons ; ribonucleases ; terminal repeat sequences ; transposons
Language	English
Dates of publication	2016-06
Size	p. 325-333.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	2165-9
ISSN	1573-6857 ; 0016-6707
ISSN (online)	1573-6857
ISSN	0016-6707
DOI	10.1007/s10709-016-9901-6
Database	NAL-Catalogue (AGRICOLA)

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