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  1. Article ; Online: Experimental Evidence for an Attractive p-ϕ Interaction.

    Acharya, S / Adamová, D / Adler, A / Adolfsson, J / Aglieri Rinella, G / Agnello, M / Agrawal, N / Ahammed, Z / Ahmad, S / Ahn, S U / Ahuja, I / Akbar, Z / Akindinov, A / Al-Turany, M / Alam, S N / Aleksandrov, D / Alessandro, B / Alfanda, H M / Alfaro Molina, R /
    Ali, B / Ali, Y / Alici, A / Alizadehvandchali, N / Alkin, A / Alme, J / Alt, T / Altenkamper, L / Altsybeev, I / Anaam, M N / Andrei, C / Andreou, D / Andronic, A / Angeletti, M / Anguelov, V / Antinori, F / Antonioli, P / Anuj, C / Apadula, N / Aphecetche, L / Appelshäuser, H / Arcelli, S / Arnaldi, R / Arsene, I C / Arslandok, M / Augustinus, A / Averbeck, R / Aziz, S / Azmi, M D / Badalà, A / Baek, Y W / Bai, X / Bailhache, R / Bailung, Y / Bala, R / Balbino, A / Baldisseri, A / Balis, B / Ball, M / Banerjee, D / Barbera, R / Barioglio, L / Barlou, M / Barnaföldi, G G / Barnby, L S / Barret, V / Bartels, C / Barth, K / Bartsch, E / Baruffaldi, F / Bastid, N / Basu, S / Batigne, G / Batyunya, B / Bauri, D / Bazo Alba, J L / Bearden, I G / Beattie, C / Belikov, I / Bell Hechavarria, A D C / Bellini, F / Bellwied, R / Belokurova, S / Belyaev, V / Bencedi, G / Beole, S / Bercuci, A / Berdnikov, Y / Berdnikova, A / Berenyi, D / Bergmann, L / Besoiu, M G / Betev, L / Bhaduri, P P / Bhasin, A / Bhat, I R / Bhat, M A / Bhattacharjee, B / Bhattacharya, P / Bianchi, L / Bianchi, N / Bielčík, J / Bielčíková, J / Biernat, J / Bilandzic, A / Biro, G / Biswas, S / Blair, J T / Blau, D / Blidaru, M B / Blume, C / Boca, G / Bock, F / Bogdanov, A / Boi, S / Bok, J / Boldizsár, L / Bolozdynya, A / Bombara, M / Bond, P M / Bonomi, G / Borel, H / Borissov, A / Bossi, H / Botta, E / Bratrud, L / Braun-Munzinger, P / Bregant, M / Broz, M / Bruno, G E / Buckland, M D / Budnikov, D / Buesching, H / Bufalino, S / Bugnon, O / Buhler, P / Buthelezi, Z / Butt, J B / Bysiak, S A / Caffarri, D / Cai, M / Caines, H / Caliva, A / Calvo Villar, E / Camacho, J M M / Camacho, R S / Camerini, P / Canedo, F D M / Carnesecchi, F / Caron, R / Castillo Castellanos, J / Casula, E A R / Catalano, F / Ceballos Sanchez, C / Chakraborty, P / Chandra, S / Chapeland, S / Chartier, M / Chattopadhyay, S / Chauvin, A / Chavez, T G / Cheshkov, C / Cheynis, B / Chibante Barroso, V / Chinellato, D D / Chizzali, E S / Cho, S / Chochula, P / Christakoglou, P / Christensen, C H / Christiansen, P / Chujo, T / Cicalo, C / Cifarelli, L / Cindolo, F / Ciupek, M R / Clai, G / Cleymans, J / Colamaria, F / Colburn, J S / Colella, D / Collu, A / Colocci, M / Concas, M / Conesa Balbastre, G / Conesa Del Valle, Z / Contin, G / Contreras, J G / Coquet, M L / Cormier, T M / Cortese, P / Cosentino, M R / Costa, F / Costanza, S / Crochet, P / Cuautle, E / Cui, P / Cunqueiro, L / Dainese, A / Damas, F P A / Danisch, M C / Danu, A / Das, I / Das, P / Das, S / Dash, S / De, S / De Caro, A / de Cataldo, G / De Cilladi, L / de Cuveland, J / De Falco, A / De Gruttola, D / De Marco, N / De Martin, C / De Pasquale, S / Deb, S / Degenhardt, H F / Deja, K R / Del Grande, R / Dello Stritto, L / Delsanto, S / Deng, W / Dhankher, P / Di Bari, D / Di Mauro, A / Diaz, R A / Dietel, T / Ding, Y / Divià, R / Dixit, D U / Djuvsland, Ø / Dmitrieva, U / Do, J / Dobrin, A / Dönigus, B / Dordic, O / Dubey, A K / Dubla, A / Dudi, S / Dukhishyam, M / Dupieux, P / Dzalaiova, N / Eder, T M / Ehlers, R J / Eikeland, V N / Eisenhut, F / Elia, D / Erazmus, B / Ercolessi, F / Erhardt, F / Erokhin, A / Ersdal, M R / Espagnon, B / Eulisse, G / Evans, D / Evdokimov, S / Fabbietti, L / Faggin, M / Faivre, J / Fan, F / Fantoni, A / Fasel, M / Fecchio, P / Feliciello, A / Feofilov, G / Fernández Téllez, A / Ferrero, A / Ferretti, A / Feuillard, V J G / Figiel, J / Filchagin, S / Finogeev, D / Fionda, F M / Fiorenza, G / Flor, F / Flores, A N / Foertsch, S / Foka, P / Fokin, S / Fragiacomo, E / Frajna, E / Fuchs, U / Funicello, N / Furget, C / Furs, A / Gaardhøje, J J / Gagliardi, M / Gago, A M / Gal, A / Galvan, C D / Ganoti, P / Garabatos, C / Garcia, J R A / Garcia-Solis, E / Garg, K / Gargiulo, C / Garibli, A / Garner, K / Gasik, P / Gauger, E F / Gautam, A / Gay Ducati, M B / Germain, M / Ghosh, J / Ghosh, P / Ghosh, S K / Giacalone, M / Gianotti, P / Giubellino, P / Giubilato, P / Glaenzer, A M C / Glässel, P / Goh, D J Q / Gonzalez, V / González-Trueba, L H / Gorbunov, S / Gorgon, M / Görlich, L / Gotovac, S / Grabski, V / Graczykowski, L K / Greiner, L / Grelli, A / Grigoras, C / Grigoriev, V / Grigoryan, A / Grigoryan, S / Groettvik, O S / Grosa, F / Grosse-Oetringhaus, J F / Grosso, R / Guardiano, G G / Guernane, R / Guilbaud, M / Gulbrandsen, K / Gunji, T / Gupta, A / Gupta, R / Guzman, I B / Guzman, S P / Gyulai, L / Habib, M K / Hadjidakis, C / Halimoglu, G / Hamagaki, H / Hamar, G / Hamid, M / Hannigan, R / Haque, M R / Harlenderova, A / Harris, J W / Harton, A / Hasenbichler, J A / Hassan, H / Hatzifotiadou, D / Hauer, P / Havener, L B / Hayashi, S / Heckel, S T / Hellbär, E / Helstrup, H / Herman, T / Hernandez, E G / Herrera Corral, G / Herrmann, F / Hetland, K F / Hillemanns, H / Hills, C / Hippolyte, B / Hofman, B / Hohlweger, B / Honermann, J / Hong, G H / Horak, D / Hornung, S / Horzyk, A / Hosokawa, R / Hristov, P / Huang, C / Hughes, C / Huhn, P / Humanic, T J / Hushnud, H / Husova, L A / Hutson, A / Hutter, D / Iddon, J P / Ilkaev, R / Ilyas, H / Inaba, M / Innocenti, G M / Ippolitov, M / Isakov, A / Islam, M S / Ivanov, M / Ivanov, V / Izucheev, V / Jablonski, M / Jacak, B / Jacazio, N / Jacobs, P M / Jadlovska, S / Jadlovsky, J / Jaelani, S / Jahnke, C / Jakubowska, M J / Janik, M A / Janson, T / Jercic, M / Jevons, O / Jonas, F / Jones, P G / Jowett, J M / Jung, J / Jung, M / Junique, A / Jusko, A / Kaewjai, J / Kalinak, P / Kalweit, A / Kaplin, V / Kar, S / Karasu Uysal, A / Karatovic, D / Karavichev, O / Karavicheva, T / Karczmarczyk, P / Karpechev, E / Kazantsev, A / Kebschull, U / Keidel, R / Keijdener, D L D / Keil, M / Ketzer, B / Khabanova, Z / Khan, A M / Khan, S / Khanzadeev, A / Kharlov, Y / Khatun, A / Khuntia, A / Kileng, B / Kim, B / Kim, D / Kim, D J / Kim, E J / Kim, J / Kim, J S / Kim, M / Kim, S / Kim, T / Kirsch, S / Kisel, I / Kiselev, S / Kisiel, A / Kitowski, J P / Klay, J L / Klein, J / Klein, S / Klein-Bösing, C / Kleiner, M / Klemenz, T / Kluge, A / Knospe, A G / Kobdaj, C / Köhler, M K / Kollegger, T / Kondratyev, A / Kondratyeva, N / Kondratyuk, E / Konig, J / Konigstorfer, S A / Konopka, P J / Kornakov, G / Koryciak, S D / Koska, L / Kotliarov, A / Kovalenko, O / Kovalenko, V / Kowalski, M / Králik, I / Kravčáková, A / Kreis, L / Krivda, M / Krizek, F / Krizkova Gajdosova, K / Kroesen, M / Krüger, M / Kryshen, E / Krzewicki, M / Kučera, V / Kuhn, C / Kuijer, P G / Kumaoka, T / Kumar, D / Kumar, L / Kumar, N / Kundu, S / Kurashvili, P / Kurepin, A / Kurepin, A B / Kuryakin, A / Kushpil, S / Kvapil, J / Kweon, M J / Kwon, J Y / Kwon, Y / La Pointe, S L / La Rocca, P / Lai, Y S / Lakrathok, A / Lamanna, M / Langoy, R / Lapidus, K / Larionov, P / Laudi, E / Lautner, L / Lavicka, R / Lazareva, T / Lea, R / Lee, J / Lehrbach, J / Lemmon, R C / León Monzón, I / Lesser, E D / Lettrich, M / Lévai, P / Li, X / Li, X L / Lien, J / Lietava, R / Lim, B / Lim, S H / Lindenstruth, V / Lindner, A / Lippmann, C / Liu, A / Liu, J / Lofnes, I M / Loginov, V / Loizides, C / Loncar, P / Lopez, J A / Lopez, X / López Torres, E / Luhder, J R / Lunardon, M / Luparello, G / Ma, Y G / Maevskaya, A / Mager, M / Mahmoud, T / Maire, A / Malaev, M / Malik, Q W / Malinina, L / Mal'Kevich, D / Mallick, N / Malzacher, P / Mandaglio, G / Manko, V / Manso, F / Manzari, V / Mao, Y / Mareš, J / Margagliotti, G V / Margotti, A / Marín, A / Markert, C / Marquard, M / Martin, N A / Martinengo, P / Martinez, J L / Martínez, M I / Martínez García, G / Masciocchi, S / Masera, M / Masoni, A / Massacrier, L / Mastroserio, A / Mathis, A M / Matonoha, O / Matuoka, P F T / Matyja, A / Mayer, C / Mazuecos, A L / Mazzaschi, F / Mazzilli, M / Mazzoni, M A / Mdhluli, J E / Mechler, A F / Meddi, F / Melikyan, Y / Menchaca-Rocha, A / Meninno, E / Menon, A S / Meres, M / Mhlanga, S / Miake, Y / Micheletti, L / Migliorin, L C / Mihaylov, D L / Mikhaylov, K / Mishra, A N / Miśkowiec, D / Modak, A / Mohanty, A P / Mohanty, B / Mohisin Khan, M / Moravcova, Z / Mordasini, C / Moreira De Godoy, D A / Moreno, L A P / Morozov, I / Morsch, A / Mrnjavac, T / Muccifora, V / Mudnic, E / Mühlheim, D / Muhuri, S / Mulligan, J D / Mulliri, A / Munhoz, M G / Munzer, R H / Murakami, H / Murray, S / Musa, L / Musinsky, J / Myers, C J / Myrcha, J W / Naik, B / Nair, R / Nandi, B K / Nania, R / Nappi, E / Naru, M U / Nassirpour, A F / Nath, A / Nattrass, C / Neagu, A / Nellen, L / Nesbo, S V / Neskovic, G / Nesterov, D / Nielsen, B S / Nikolaev, S / Nikulin, S / Nikulin, V / Noferini, F / Noh, S / Nomokonov, P / Norman, J / Novitzky, N / Nowakowski, P / Nyanin, A / Nystrand, J / Ogino, M / Ohlson, A / Okorokov, V A / Oleniacz, J / Oliveira Da Silva, A C / Oliver, M H / Onnerstad, A / Oppedisano, C / Ortiz Velasquez, A / Osako, T / Oskarsson, A / Otwinowski, J / Oyama, K / Pachmayer, Y / Padhan, S / Pagano, D / Paić, G / Palasciano, A / Pan, J / Panebianco, S / Pareek, P / Park, J / Parkkila, J E / Pathak, S P / Patra, R N / Paul, B / Pazzini, J / Pei, H / Peitzmann, T / Peng, X / Pereira, L G / Pereira Da Costa, H / Peresunko, D / Perez, G M / Perrin, S / Pestov, Y / Petráček, V / Petrovici, M / Pezzi, R P / Piano, S / Pikna, M / Pillot, P / Pinazza, O / Pinsky, L / Pinto, C / Pisano, S / Płoskoń, M / Planinic, M / Pliquett, F / Poghosyan, M G / Polichtchouk, B / Politano, S / Poljak, N / Pop, A / Porteboeuf-Houssais, S / Porter, J / Pozdniakov, V / Prasad, S K / Preghenella, R / Prino, F / Pruneau, C A / Pshenichnov, I / Puccio, M / Qiu, S / Quaglia, L / Quishpe, R E / Ragoni, S / Rakotozafindrabe, A / Ramello, L / Rami, F / Ramirez, S A R / Ramos, A G T / Rancien, T A / Raniwala, R / Raniwala, S / Räsänen, S S / Rath, R / Ravasenga, I / Read, K F / Redelbach, A R / Redlich, K / Rehman, A / Reichelt, P / Reidt, F / Reme-Ness, H A / Renfordt, R / Rescakova, Z / Reygers, K / Riabov, A / Riabov, V / Richert, T / Richter, M / Riegler, W / Riggi, F / Ristea, C / Rode, S P / Rodríguez Cahuantzi, M / Røed, K / Rogalev, R / Rogochaya, E / Rogoschinski, T S / Rohr, D / Röhrich, D / Rojas, P F / Rokita, P S / Ronchetti, F / Rosano, A / Rosas, E D / Rossi, A / Rotondi, A / Roy, A / Roy, P / Roy, S / Rubini, N / Rueda, O V / Rui, R / Rumyantsev, B / Russek, P G / Rustamov, A / Ryabinkin, E / Ryabov, Y / Rybicki, A / Rytkonen, H / Rzesa, W / Saarimaki, O A M / Sadek, R / Sadovsky, S / Saetre, J / Šafařík, K / Saha, S K / Saha, S / Sahoo, B / Sahoo, P / Sahoo, R / Sahoo, S / Sahu, D / Sahu, P K / Saini, J / Sakai, S / Sambyal, S / Samsonov, V / Sarkar, D / Sarkar, N / Sarma, P / Sarti, V M / Sas, M H P / Schambach, J / Scheid, H S / Schiaua, C / Schicker, R / Schmah, A / Schmidt, C / Schmidt, H R / Schmidt, M O / Schmidt, M / Schmidt, N V / Schmier, A R / Schotter, R / Schukraft, J / Schutz, Y / Schwarz, K / Schweda, K / Scioli, G / Scomparin, E / Seger, J E / Sekiguchi, Y / Sekihata, D / Selyuzhenkov, I / Senyukov, S / Seo, J J / Serebryakov, D / Šerkšnytė, L / Sevcenco, A / Shaba, T J / Shabanov, A / Shabetai, A / Shahoyan, R / Shaikh, W / Shangaraev, A / Sharma, A / Sharma, H / Sharma, M / Sharma, N / Sharma, S / Sheibani, O / Shigaki, K / Shimomura, M / Shirinkin, S / Shou, Q / Sibiriak, Y / Siddhanta, S / Siemiarczuk, T / Silva, T F / Silvermyr, D / Simonetti, G / Singh, B / Singh, R / Singh, V K / Singhal, V / Sinha, T / Sitar, B / Sitta, M / Skaali, T B / Skorodumovs, G / Slupecki, M / Smirnov, N / Snellings, R J M / Soncco, C / Song, J / Songmoolnak, A / Soramel, F / Sorensen, S / Sputowska, I / Stachel, J / Stan, I / Steffanic, P J / Stiefelmaier, S F / Stocco, D / Storehaug, I / Storetvedt, M M / Stylianidis, C P / Suaide, A A P / Sugitate, T / Suire, C / Suljic, M / Sultanov, R / Šumbera, M / Sumberia, V / Sumowidagdo, S / Swain, S / Szabo, A / Szarka, I / Tabassam, U / Taghavi, S F / Taillepied, G / Takahashi, J / Tambave, G J / Tang, S / Tang, Z / Tarhini, M / Tarzila, M G / Tauro, A / Tejeda Muñoz, G / Telesca, A / Terlizzi, L / Terrevoli, C / Tersimonov, G / Thakur, S / Thomas, D / Tieulent, R / Tikhonov, A / Timmins, A R / Tkacik, M / Toia, A / Topilskaya, N / Toppi, M / Torales-Acosta, F / Tork, T / Cruz-Torres, R / Torres, S R / Trifiró, A / Tripathy, S / Tripathy, T / Trogolo, S / Trombetta, G / Trubnikov, V / Trzaska, W H / Trzcinski, T P / Trzeciak, B A / Tumkin, A / Turrisi, R / Tveter, T S / Ullaland, K / Uras, A / Urioni, M / Usai, G L / Vala, M / Valle, N / Vallero, S / van der Kolk, N / van Doremalen, L V R / van Leeuwen, M / Vande Vyvre, P / Varga, D / Varga, Z / Varga-Kofarago, M / Vargas, A / Vasileiou, M / Vasiliev, A / Vázquez Doce, O / Vechernin, V / Vercellin, E / Vergara Limón, S / Vermunt, L / Vértesi, R / Verweij, M / Vickovic, L / Vilakazi, Z / Villalobos Baillie, O / Vino, G / Vinogradov, A / Virgili, T / Vislavicius, V / Vodopyanov, A / Volkel, B / Völkl, M A / Voloshin, K / Voloshin, S A / Volpe, G / von Haller, B / Vorobyev, I / Voscek, D / Vrláková, J / Wagner, B / Wang, C / Wang, D / Weber, M / Weelden, R J G V / Wegrzynek, A / Wenzel, S C / Wessels, J P / Wiechula, J / Wikne, J / Wilk, G / Wilkinson, J / Willems, G A / Willsher, E / Windelband, B / Winn, M / Witt, W E / Wright, J R / Wu, W / Wu, Y / Xu, R / Yalcin, S / Yamaguchi, Y / Yamakawa, K / Yang, S / Yano, S / Yin, Z / Yokoyama, H / Yoo, I-K / Yoon, J H / Yuan, S / Yuncu, A / Zaccolo, V / Zaman, A / Zampolli, C / Zanoli, H J C / Zardoshti, N / Zarochentsev, A / Závada, P / Zaviyalov, N / Zbroszczyk, H / Zhalov, M / Zhang, S / Zhang, X / Zhang, Y / Zherebchevskii, V / Zhi, Y / Zhou, D / Zhou, Y / Zhu, J / Zhu, Y / Zichichi, A / Zinovjev, G / Zurlo, N

    Physical review letters

    2021  Volume 127, Issue 17, Page(s) 172301

    Abstract: ... a proton and a ϕ meson. The result is obtained from two-particle correlations of combined p-ϕ⊕ p[over ¯]-ϕ ... The spin-averaged scattering length and effective range of the p-ϕ interaction are extracted from the fully ... role for the p-ϕ interaction. These data demonstrate that the interaction is dominated by elastic p-ϕ ...

    Abstract This Letter presents the first experimental evidence of the attractive strong interaction between a proton and a ϕ meson. The result is obtained from two-particle correlations of combined p-ϕ⊕ p[over ¯]-ϕ pairs measured in high-multiplicity pp collisions at sqrt[s]=13  TeV by the ALICE Collaboration. The spin-averaged scattering length and effective range of the p-ϕ interaction are extracted from the fully corrected correlation function employing the Lednický-Lyuboshits approach. In particular, the imaginary part of the scattering length vanishes within uncertainties, indicating that inelastic processes do not play a prominent role for the p-ϕ interaction. These data demonstrate that the interaction is dominated by elastic p-ϕ scattering. Furthermore, an analysis employing phenomenological Gaussian- and Yukawa-type potentials is conducted. Under the assumption of the latter, the N-ϕ coupling constant is found to be g_{N-ϕ}=0.14±0.03(stat)±0.02(syst). This work provides valuable experimental input to accomplish a self-consistent description of the N-ϕ interaction, which is particularly relevant for the more fundamental studies on partial restoration of chiral symmetry in nuclear medium.
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.127.172301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Lysophosphatidylcholines are associated with P-tau181 levels in early stages of Alzheimer's Disease.

    Vardarajan, Badri / Kalia, Vrinda / Reyes-Dumeyer, Dolly / Dubey, Saurabh / Nandakumar, Renu / Lee, Annie / Lantigua, Rafael / Medrano, Martin / Rivera, Diones / Honig, Lawrence / Mayeux, Richard / Miller, Gary

    Research square

    2024  

    Abstract: ... of Caribbean Hispanic ancestry. Plasma biomarkers of AD were measured including P-tau181, Aβ40, Aβ42, total-tau ... AD pathological process based on P-tau181 and other biomarker levels.: Results: Over 6000 ... arachidonic acid (AHA) was associated with decreased risk of AD (OR = 0.91 [0.89-0.96], p = 2e-04). Association was ...

    Abstract Background: We profiled circulating plasma metabolites to identify systemic biochemical changes in clinical and biomarker-assisted diagnosis of Alzheimer's disease (AD).
    Methods: We used an untargeted approach with liquid chromatography coupled to high-resolution mass spectrometry to measure small molecule plasma metabolites from 150 clinically diagnosed AD patients and 567 age-matched healthy elderly of Caribbean Hispanic ancestry. Plasma biomarkers of AD were measured including P-tau181, Aβ40, Aβ42, total-tau, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP). Association of individual and co-abundant modules of metabolites were tested with clinical diagnosis of AD, as well as biologically-defined AD pathological process based on P-tau181 and other biomarker levels.
    Results: Over 6000 metabolomic features were measured with high accuracy. First principal component (PC) of lysophosphatidylcholines (lysoPC) that bind to or interact with docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and arachidonic acid (AHA) was associated with decreased risk of AD (OR = 0.91 [0.89-0.96], p = 2e-04). Association was restricted to individuals without an
    Conclusions: Unbiased metabolic profiling can identify critical metabolites and pathways associated with β-amyloid and phosphotau pathology. We also observed an
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-3346076/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Response to: Letter from P. Gillard and B. Benninghoff.

    Rathi, Niraj / Desai, Sajjad / Kawade, Anand / Venkatramanan, Padmasani / Kundu, Ritabrata / Lalwani, Sanjay K / Dubey, A P / Venkateswara Rao, J / Narayanappa, D / Ghildiyal, Radha / Gogtay, Nithya J / Venugopal, P / Palkar, Sonali / Munshi, Renuka / Kang, Gagandeep / Babji, Sudhir / Bavdekar, Ashish / Juvekar, Sanjay / Ganguly, Nupur /
    Niyogi, Prabal / Uttam, Kheya Ghosh / Rajani, H S / Kondekar, Alpana / Kumbhar, Dipti / Mohanlal, Smilu / Agarwal, Mukesh C / Shetty, Parvan / Antony, Kalpana / Gunale, Bhagwat / Dharmadhikari, Abhijeet / Tang, Yuxiao / Kulkarni, Prasad S / Flores, Jorge

    Vaccine

    2019  Volume 37, Issue 23, Page(s) 2991–2992

    MeSH term(s) Animals ; Asian Continental Ancestry Group ; Cattle ; Humans ; Infant ; Research Design ; Rotavirus ; Vaccination
    Language English
    Publishing date 2019-05-09
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2019.04.002
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  4. Article ; Online: Serine phosphorylation regulates the P-type potassium pump KdpFABC.

    Sweet, Marie E / Zhang, Xihui / Erdjument-Bromage, Hediye / Dubey, Vikas / Khandelia, Himanshu / Neubert, Thomas A / Pedersen, Bjørn P / Stokes, David L

    eLife

    2020  Volume 9

    Abstract: KdpFABC is an ATP-dependent ... ...

    Abstract KdpFABC is an ATP-dependent K
    MeSH term(s) Adenosine Triphosphatases/chemistry ; Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Cation Transport Proteins/chemistry ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Mutation/genetics ; P-type ATPases/chemistry ; P-type ATPases/genetics ; P-type ATPases/metabolism ; Phosphorylation/genetics ; Potassium/metabolism ; Serine/metabolism
    Chemical Substances Cation Transport Proteins ; Escherichia coli Proteins ; Serine (452VLY9402) ; Adenosine Triphosphatases (EC 3.6.1.-) ; potassium translocating Kdp-ATPase, E coli (EC 3.6.1.-) ; P-type ATPases (EC 3.6.3.-) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2020-09-21
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.55480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Lysophosphatidylcholines are associated with P-tau181 levels in early stages of Alzheimer's Disease.

    Kalia, Vrinda / Reyes-Dumeyer, Dolly / Dubey, Saurabh / Nandakumar, Renu / Lee, Annie J / Lantigua, Rafael / Medrano, Martin / Rivera, Diones / Honig, Lawrence S / Mayeux, Richard / Miller, Gary W / Vardarajan, Badri N

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: ... Hispanic ancestry. Plasma biomarkers of AD were also measured including P-tau181, Aβ40, Aβ42, total tau ... defined AD pathological process based on P-tau181 and other biomarker levels.: Results: Over 4000 ... arachidonic acid (AHA) was associated with decreased risk of AD (OR=0.91 [0.89-0.96], p=2e-04). Restricted ...

    Abstract Background: We investigated systemic biochemical changes in Alzheimer's disease (AD) by investigating the relationship between circulating plasma metabolites and both clinical and biomarker-assisted diagnosis of AD.
    Methods: We used an untargeted approach with liquid chromatography coupled to high-resolution mass spectrometry to measure exogenous and endogenous small molecule metabolites in plasma from 150 individuals clinically diagnosed with AD and 567 age-matched elderly without dementia of Caribbean Hispanic ancestry. Plasma biomarkers of AD were also measured including P-tau181, Aβ40, Aβ42, total tau, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP). Association of individual and co-expressed modules of metabolites were tested with the clinical diagnosis of AD, as well as biologically-defined AD pathological process based on P-tau181 and other biomarker levels.
    Results: Over 4000 metabolomic features were measured with high accuracy. First principal component (PC) of lysophosphatidylcholines (lysoPC) that bind to or interact with docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and arachidonic acid (AHA) was associated with decreased risk of AD (OR=0.91 [0.89-0.96], p=2e-04). Restricted to individuals without an
    Conclusions: Our findings indicate that unbiased metabolic profiling can identify critical metabolites and pathways associated with β-amyloid and phosphotau pathology. We also observed an
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.24.23294581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hypertriton Production in p-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

    Acharya, S / Adamová, D / Adler, A / Aglieri Rinella, G / Agnello, M / Agrawal, N / Ahammed, Z / Ahmad, S / Ahn, S U / Ahuja, I / Akbar, Z / Akindinov, A / Al-Turany, M / Alam, S N / Aleksandrov, D / Alessandro, B / Alfanda, H M / Alfaro Molina, R / Ali, B /
    Ali, Y / Alici, A / Alizadehvandchali, N / Alkin, A / Alme, J / Alt, T / Altenkamper, L / Altsybeev, I / Anaam, M N / Andrei, C / Andreou, D / Andronic, A / Angeletti, M / Anguelov, V / Antinori, F / Antonioli, P / Anuj, C / Apadula, N / Aphecetche, L / Appelshäuser, H / Arcelli, S / Arnaldi, R / Arsene, I C / Arslandok, M / Augustinus, A / Averbeck, R / Aziz, S / Azmi, M D / Badalà, A / Baek, Y W / Bai, X / Bailhache, R / Bailung, Y / Bala, R / Balbino, A / Baldisseri, A / Balis, B / Ball, M / Banerjee, D / Barbera, R / Barioglio, L / Barlou, M / Barnaföldi, G G / Barnby, L S / Barret, V / Bartels, C / Barth, K / Bartsch, E / Baruffaldi, F / Bastid, N / Basu, S / Batigne, G / Batyunya, B / Bauri, D / Bazo Alba, J L / Bearden, I G / Beattie, C / Belikov, I / Bell Hechavarria, A D C / Bellini, F / Bellwied, R / Belokurova, S / Belyaev, V / Bencedi, G / Beole, S / Bercuci, A / Berdnikov, Y / Berdnikova, A / Bergmann, L / Besoiu, M G / Betev, L / Bhaduri, P P / Bhasin, A / Bhat, I R / Bhat, M A / Bhattacharjee, B / Bhattacharya, P / Bianchi, L / Bianchi, N / Bielčík, J / Bielčíková, J / Biernat, J / Bilandzic, A / Biro, G / Biswas, S / Blair, J T / Blau, D / Blidaru, M B / Blume, C / Boca, G / Bock, F / Bogdanov, A / Boi, S / Bok, J / Boldizsár, L / Bolozdynya, A / Bombara, M / Bond, P M / Bonomi, G / Borel, H / Borissov, A / Bossi, H / Botta, E / Bratrud, L / Braun-Munzinger, P / Bregant, M / Broz, M / Bruno, G E / Buckland, M D / Budnikov, D / Buesching, H / Bufalino, S / Bugnon, O / Buhler, P / Buthelezi, Z / Butt, J B / Bysiak, S A / Cai, M / Caines, H / Caliva, A / Calvo Villar, E / Camacho, J M M / Camacho, R S / Camerini, P / Canedo, F D M / Carnesecchi, F / Caron, R / Castillo Castellanos, J / Casula, E A R / Catalano, F / Ceballos Sanchez, C / Chakraborty, P / Chandra, S / Chapeland, S / Chartier, M / Chattopadhyay, S / Chauvin, A / Chavez, T G / Cheng, T / Cheshkov, C / Cheynis, B / Chibante Barroso, V / Chinellato, D D / Cho, S / Chochula, P / Christakoglou, P / Christensen, C H / Christiansen, P / Chujo, T / Cicalo, C / Cifarelli, L / Cindolo, F / Ciupek, M R / Clai, G / Cleymans, J / Colamaria, F / Colburn, J S / Colella, D / Collu, A / Colocci, M / Concas, M / Conesa Balbastre, G / Conesa Del Valle, Z / Contin, G / Contreras, J G / Coquet, M L / Cormier, T M / Cortese, P / Cosentino, M R / Costa, F / Costanza, S / Crochet, P / Cruz-Torres, R / Cuautle, E / Cui, P / Cunqueiro, L / Dainese, A / Danisch, M C / Danu, A / Das, I / Das, P / Das, S / Dash, S / De, S / De Caro, A / de Cataldo, G / De Cilladi, L / de Cuveland, J / De Falco, A / De Gruttola, D / De Marco, N / De Martin, C / De Pasquale, S / Deb, S / Degenhardt, H F / Deja, K R / Dello Stritto, L / Delsanto, S / Deng, W / Dhankher, P / Di Bari, D / Di Mauro, A / Diaz, R A / Dietel, T / Ding, Y / Divià, R / Dixit, D U / Djuvsland, Ø / Dmitrieva, U / Do, J / Dobrin, A / Dönigus, B / Dordic, O / Dubey, A K / Dubla, A / Dudi, S / Dukhishyam, M / Dupieux, P / Dzalaiova, N / Eder, T M / Ehlers, R J / Eikeland, V N / Eisenhut, F / Elia, D / Erazmus, B / Ercolessi, F / Erhardt, F / Erokhin, A / Ersdal, M R / Espagnon, B / Eulisse, G / Evans, D / Evdokimov, S / Fabbietti, L / Faggin, M / Faivre, J / Fan, F / Fantoni, A / Fasel, M / Fecchio, P / Feliciello, A / Feofilov, G / Fernández Téllez, A / Ferrero, A / Ferretti, A / Feuillard, V J G / Figiel, J / Filchagin, S / Finogeev, D / Fionda, F M / Fiorenza, G / Flor, F / Flores, A N / Foertsch, S / Foka, P / Fokin, S / Fragiacomo, E / Frajna, E / Fuchs, U / Funicello, N / Furget, C / Furs, A / Gaardhøje, J J / Gagliardi, M / Gago, A M / Gal, A / Galvan, C D / Ganoti, P / Garabatos, C / Garcia, J R A / Garcia-Solis, E / Garg, K / Gargiulo, C / Garibli, A / Garner, K / Gasik, P / Gauger, E F / Gautam, A / Gay Ducati, M B / Germain, M / Ghosh, P / Ghosh, S K / Giacalone, M / Gianotti, P / Giubellino, P / Giubilato, P / Glaenzer, A M C / Glässel, P / Goh, D J Q / Gonzalez, V / González-Trueba, L H / Gorbunov, S / Gorgon, M / Görlich, L / Gotovac, S / Grabski, V / Graczykowski, L K / Greiner, L / Grelli, A / Grigoras, C / Grigoriev, V / Grigoryan, A / Grigoryan, S / Groettvik, O S / Grosa, F / Grosse-Oetringhaus, J F / Grosso, R / Guardiano, G G / Guernane, R / Guilbaud, M / Gulbrandsen, K / Gunji, T / Guo, W / Gupta, A / Gupta, R / Guzman, S P / Gyulai, L / Habib, M K / Hadjidakis, C / Halimoglu, G / Hamagaki, H / Hamar, G / Hamid, M / Hannigan, R / Haque, M R / Harlenderova, A / Harris, J W / Harton, A / Hasenbichler, J A / Hassan, H / Hatzifotiadou, D / Hauer, P / Havener, L B / Hayashi, S / Heckel, S T / Hellbär, E / Helstrup, H / Herman, T / Hernandez, E G / Herrera Corral, G / Herrmann, F / Hetland, K F / Hillemanns, H / Hills, C / Hippolyte, B / Hofman, B / Hohlweger, B / Honermann, J / Hong, G H / Horak, D / Hornung, S / Horzyk, A / Hosokawa, R / Hou, Y / Hristov, P / Hughes, C / Huhn, P / Humanic, T J / Hushnud, H / Husova, L A / Hutson, A / Hutter, D / Iddon, J P / Ilkaev, R / Ilyas, H / Inaba, M / Innocenti, G M / Ippolitov, M / Isakov, A / Islam, M S / Ivanov, M / Ivanov, V / Izucheev, V / Jablonski, M / Jacak, B / Jacazio, N / Jacobs, P M / Jadlovska, S / Jadlovsky, J / Jaelani, S / Jahnke, C / Jakubowska, M J / Jalotra, A / Janik, M A / Janson, T / Jercic, M / Jevons, O / Jimenez, A A P / Jonas, F / Jones, P G / Jowett, J M / Jung, J / Jung, M / Junique, A / Jusko, A / Kaewjai, J / Kalinak, P / Kalweit, A / Kaplin, V / Kar, S / Karasu Uysal, A / Karatovic, D / Karavichev, O / Karavicheva, T / Karczmarczyk, P / Karpechev, E / Kazantsev, A / Kebschull, U / Keidel, R / Keijdener, D L D / Keil, M / Ketzer, B / Khabanova, Z / Khan, A M / Khan, S / Khanzadeev, A / Kharlov, Y / Khatun, A / Khuntia, A / Kileng, B / Kim, B / Kim, C / Kim, D J / Kim, E J / Kim, J / Kim, J S / Kim, M / Kim, S / Kim, T / Kirsch, S / Kisel, I / Kiselev, S / Kisiel, A / Kitowski, J P / Klay, J L / Klein, J / Klein, S / Klein-Bösing, C / Kleiner, M / Klemenz, T / Kluge, A / Knospe, A G / Kobdaj, C / Köhler, M K / Kollegger, T / Kondratyev, A / Kondratyeva, N / Kondratyuk, E / Konig, J / Konigstorfer, S A / Konopka, P J / Kornakov, G / Koryciak, S D / Koska, L / Kotliarov, A / Kovalenko, O / Kovalenko, V / Kowalski, M / Králik, I / Kravčáková, A / Kreis, L / Krivda, M / Krizek, F / Krizkova Gajdosova, K / Kroesen, M / Krüger, M / Kryshen, E / Krzewicki, M / Kučera, V / Kuhn, C / Kuijer, P G / Kumaoka, T / Kumar, D / Kumar, L / Kumar, N / Kundu, S / Kurashvili, P / Kurepin, A / Kurepin, A B / Kuryakin, A / Kushpil, S / Kvapil, J / Kweon, M J / Kwon, J Y / Kwon, Y / La Pointe, S L / La Rocca, P / Lai, Y S / Lakrathok, A / Lamanna, M / Langoy, R / Lapidus, K / Larionov, P / Laudi, E / Lautner, L / Lavicka, R / Lazareva, T / Lea, R / Lehrbach, J / Lemmon, R C / León Monzón, I / Lesser, E D / Lettrich, M / Lévai, P / Li, X / Li, X L / Lien, J / Lietava, R / Lim, B / Lim, S H / Lindenstruth, V / Lindner, A / Lippmann, C / Liu, A / Liu, D H / Liu, J / Lofnes, I M / Loginov, V / Loizides, C / Loncar, P / Lopez, J A / Lopez, X / López Torres, E / Luhder, J R / Lunardon, M / Luparello, G / Ma, Y G / Maevskaya, A / Mager, M / Mahmoud, T / Maire, A / Malaev, M / Malik, N M / Malik, Q W / Malinina, L / Mal'Kevich, D / Mallick, N / Malzacher, P / Mandaglio, G / Manko, V / Manso, F / Manzari, V / Mao, Y / Mareš, J / Margagliotti, G V / Margotti, A / Marín, A / Markert, C / Marquard, M / Martin, N A / Martinengo, P / Martinez, J L / Martínez, M I / Martínez García, G / Masciocchi, S / Masera, M / Masoni, A / Massacrier, L / Mastroserio, A / Mathis, A M / Matonoha, O / Matuoka, P F T / Matyja, A / Mayer, C / Mazuecos, A L / Mazzaschi, F / Mazzilli, M / Mazzoni, M A / Mdhluli, J E / Mechler, A F / Meddi, F / Melikyan, Y / Menchaca-Rocha, A / Meninno, E / Menon, A S / Meres, M / Mhlanga, S / Miake, Y / Micheletti, L / Migliorin, L C / Mihaylov, D L / Mikhaylov, K / Mishra, A N / Miśkowiec, D / Modak, A / Mohanty, A P / Mohanty, B / Mohisin Khan, M / Molander, M A / 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/ Sharma, A / Sharma, H / Sharma, M / Sharma, N / Sharma, S / Sharma, U / Sheibani, O / Shigaki, K / Shimomura, M / Shirinkin, S / Shou, Q / Sibiriak, Y / Siddhanta, S / Siemiarczuk, T / Silva, T F / Silvermyr, D / Simantathammakul, T / Simonetti, G / Singh, B / Singh, R / Singh, V K / Singhal, V / Sinha, T / Sitar, B / Sitta, M / Skaali, T B / Skorodumovs, G / Slupecki, M / Smirnov, N / Snellings, R J M / Soncco, C / Song, J / Songmoolnak, A / Soramel, F / Sorensen, S / Sputowska, I / Stachel, J / Stan, I / Steffanic, P J / Stiefelmaier, S F / Stocco, D / Storehaug, I / Storetvedt, M M / Stylianidis, C P / Suaide, A A P / Sugitate, T / Suire, C / Sukhanov, M / Suljic, M / Sultanov, R / Šumbera, M / Sumberia, V / Sumowidagdo, S / Swain, S / Szabo, A / Szarka, I / Tabassam, U / Taghavi, S F / Taillepied, G / Takahashi, J / Tambave, G J / Tang, S / Tang, Z / Tarhini, M / Tarzila, M G / Tauro, A / Tejeda Muñoz, G / Telesca, A / Terlizzi, L / Terrevoli, C / Tersimonov, G / Thakur, S / 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    Physical review letters

    2022  Volume 128, Issue 25, Page(s) 252003

    Abstract: ... of the production of _{Λ}^{3}H in p-Pb collisions at sqrt[s_{NN}]=5.02  TeV is presented in this Letter ... Its production yield measured in the rapidity interval -1p-Pb collisions is ... environments relevant to small collision systems such as p-Pb, and therefore the measurement of dN/dy is ...

    Abstract The study of nuclei and antinuclei production has proven to be a powerful tool to investigate the formation mechanism of loosely bound states in high-energy hadronic collisions. The first measurement of the production of _{Λ}^{3}H in p-Pb collisions at sqrt[s_{NN}]=5.02  TeV is presented in this Letter. Its production yield measured in the rapidity interval -1<y<0 for the 40% highest-multiplicity <mark>p-Pb collisions is dN/dy=[6.3±1.8(stat)±1.2(syst)]×10^{-7}. The measurement is compared with the expectations of statistical hadronization and coalescence models, which describe the nucleosynthesis in hadronic collisions. These two models predict very different yields of the hypertriton in charged particle multiplicity environments relevant to small collision systems such as p-Pb, and therefore the measurement of dN/dy is crucial to distinguish between them. The precision of this measurement leads to the exclusion with a significance larger than 6.9σ of some configurations of the statistical hadronization model, thus constraining the theory behind the production of loosely bound states at hadron colliders.
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.128.252003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A novel leishmanial copper P-type ATPase plays a vital role in parasite infection and intracellular survival.

    Paul, Rupam / Banerjee, Sourav / Sen, Samarpita / Dubey, Pratiksha / Maji, Saptarshi / Bachhawat, Anand K / Datta, Rupak / Gupta, Arnab

    The Journal of biological chemistry

    2021  Volume 298, Issue 2, Page(s) 101539

    Abstract: Copper (Cu) is essential for all life forms; however, in excess, it becomes toxic. Toxic properties of Cu are known to be utilized by host species against various pathogenic invasions. Leishmania, in both free-living and intracellular forms, exhibits ... ...

    Abstract Copper (Cu) is essential for all life forms; however, in excess, it becomes toxic. Toxic properties of Cu are known to be utilized by host species against various pathogenic invasions. Leishmania, in both free-living and intracellular forms, exhibits appreciable tolerance toward Cu stress. While determining the mechanism of Cu-stress evasion employed by Leishmania, we identified and characterized a hitherto unknown Cu-ATPase in Leishmania major and established its role in parasite survival in host macrophages. This novel L. major Cu-ATPase, LmATP7, exhibits homology with its orthologs at multiple motifs. In promastigotes, LmATP7 primarily localized at the plasma membrane. We also show that LmATP7 exhibits Cu-dependent expression patterns and complements Cu transport in a Cu-ATPase-deficient yeast strain. Promastigotes overexpressing LmATP7 exhibited higher survival upon Cu stress, indicating efficacious Cu export compared with Wt and heterozygous LmATP7 knockout parasites. We further explored macrophage-Leishmania interactions with respect to Cu stress. We found that Leishmania infection triggers upregulation of major mammalian Cu exporter, ATP7A, in macrophages, and trafficking of ATP7A from the trans-Golgi network to endolysosomes in macrophages harboring amastigotes. Simultaneously, in Leishmania, we observed a multifold increase in LmATP7 transcripts as the promastigote becomes established in macrophages and morphs to the amastigote form. Finally, overexpressing LmATP7 in parasites increases amastigote survivability within macrophages, whereas knocking it down reduces survivability drastically. Mice injected in their footpads with an LmATP7-overexpressing strain showed significantly larger lesions and higher amastigote loads as compared with controls and knockouts. These data establish the role of LmATP7 in parasite infectivity and intramacrophagic survivability.
    MeSH term(s) Animals ; Copper/metabolism ; Leishmania major/enzymology ; Leishmaniasis/metabolism ; Leishmaniasis/parasitology ; Mammals ; Mice ; P-type ATPases/metabolism
    Chemical Substances Copper (789U1901C5) ; P-type ATPases (EC 3.6.3.-)
    Language English
    Publishing date 2021-12-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2021.101539
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  8. Article ; Online: An Open-Air Palladium-Catalyzed Stereoselective O-Glycosylation of Glycals via in-situ Generation of gem-Disubstituted Methanols from p-Quinone Methides.

    Azeem, Ms Zanjila / Dubey, Ms Shashiprabha / Islam, Mr Sk Areful / Mandal, Pintu Kumar

    Chemistry, an Asian journal

    2024  Volume 19, Issue 4, Page(s) e202301013

    Abstract: ... in-situ generation of gem-disubstituted methanols from p-quinone methides to access 2,3-unsaturated gem ...

    Abstract We devised a palladium-catalyzed α-stereoselective glycosylation that incorporates oxygen via in-situ generation of gem-disubstituted methanols from p-quinone methides to access 2,3-unsaturated gem-diarylmethyl O-glycosides under open-air atmosphere at room temperature. Advantages of this environmentally friendly strategy include the absence of additives and ligands, using water as the green source of oxygen, mildest, operationally simple, exhibiting a wide functional group tolerance, and compatibility with a variety of glycal progenitors in appreciable yields. A mechanistic study has been verified via H
    Language English
    Publishing date 2024-02-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202301013
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  9. Article ; Online: Analytical developments of p-hydroxy prenylamine reference material for dope control research: Characterization and purity assessment.

    Joseph, Athira / Kumar, Gangasani Jagadeesh / Pawar, Sachin Dattram / Hirlekar, Bhakti Umesh / Bharatam, Prasad V / Konda, Satyanand / Mudiam, Mohana Krishna Reddy / Murty, Upadhyayula Suryanarayana / Sahu, P L / Dubey, Sachin / Radhakrishnanand, P / Adye, Daya Raju / Borkar, Roshan M / Thirupathi, Choppari / Kumar, Pramod

    Drug testing and analysis

    2021  Volume 14, Issue 2, Page(s) 224–232

    Abstract: ... from the market in 1988 due to cardiac arrhythmias concern. The major phase I metabolite of prenylamine is p ... hydroxy prenylamine that has a chiral center in the structure. Even though p-hydroxy prenylamine was ... liquid chromatography (HPLC) separation. However, p-hydroxy prenylamine reference material is not commercially available ...

    Abstract Prenylamine was initially used for the treatment of angina pectoris and later on withdrawn from the market in 1988 due to cardiac arrhythmias concern. The major phase I metabolite of prenylamine is p-hydroxy prenylamine that has a chiral center in the structure. Even though p-hydroxy prenylamine was synthesized earlier, it lacked complete analytical developments for chiral high-performance liquid chromatography (HPLC) separation. However, p-hydroxy prenylamine reference material is not commercially available. The innovation of this manuscript is the development and validation of a chiral HPLC separation method and more extensive characterization of the reference material than previously reported method. Therefore, it was hypothesized to develop and validate normal phase HPLC method for p-hydroxy prenylamine reference material. p-Hydroxy prenylamine was synthesized in two batches and characterized successfully using
    MeSH term(s) Chromatography, High Pressure Liquid/methods ; Mass Spectrometry ; Prenylamine/metabolism ; Spectroscopy, Fourier Transform Infrared ; Stereoisomerism
    Chemical Substances Prenylamine (K2OH82Z000)
    Language English
    Publishing date 2021-10-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2462336-2
    ISSN 1942-7611 ; 1942-7603
    ISSN (online) 1942-7611
    ISSN 1942-7603
    DOI 10.1002/dta.3171
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  10. Article: Cellulose amendment promotes P solubilization by Penicillium aculeatum in non-sterilized soil.

    Gómez-Muñoz, Beatriz / Efthymiou, Aikaterini / Dubey, Mukesh / Sølve, Jonathan / Nicolaisen, Mette / Jensen, Dan F / Nybroe, Ole / Larsen, John

    Fungal biology

    2022  Volume 126, Issue 5, Page(s) 356–365

    Abstract: Successful application of microbial biofertilizers, such as phosphorus (P) solubilizing fungi ... experiments we examined the performance of the P solubilizing fungus Penicillium aculeatum in non-sterile and ... semi-sterile (γ-irradiated) soil with different C and P sources. Results from the first experiment ...

    Abstract Successful application of microbial biofertilizers, such as phosphorus (P) solubilizing fungi to agroecosystems, is constrained from the lack of knowledge about their ecology; for example in terms of how they respond to an external input of carbon (C) to get established in the soil. In two soil incubation experiments we examined the performance of the P solubilizing fungus Penicillium aculeatum in non-sterile and semi-sterile (γ-irradiated) soil with different C and P sources. Results from the first experiment with C sources showed that starch and cellulose generally improved P solubilization by P. aculeatum measured as water extractable P (P
    MeSH term(s) Cellulose ; Sewage ; Soil ; Soil Microbiology ; Sterilization ; Talaromyces
    Chemical Substances Sewage ; Soil ; Cellulose (9004-34-6)
    Language English
    Publishing date 2022-03-23
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2532164-X
    ISSN 1878-6162 ; 1878-6146
    ISSN (online) 1878-6162
    ISSN 1878-6146
    DOI 10.1016/j.funbio.2022.03.003
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