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  1. Article ; Online: Case report of a rare cause of secondary hypertension illustrating the importance of cardio-obstetric preconception counselling.

    Meister, Theo A / Soria, Rodrigo / Bubulyte, Laura / Spano, Giancarlo / Makaloski, Vladimir / Raio, Luigi / Rexhaj, Emrush

    European heart journal. Case reports

    2024  Volume 8, Issue 3, Page(s) ytae092

    Abstract: Background: Cardiovascular diseases represent a leading cause of maternal morbidity and mortality in industrialized countries. High blood pressure during pregnancy is a major driver of short- and long-term cardiovascular health in both mother and child. ...

    Abstract Background: Cardiovascular diseases represent a leading cause of maternal morbidity and mortality in industrialized countries. High blood pressure during pregnancy is a major driver of short- and long-term cardiovascular health in both mother and child. Screening and adequate treatment of elevated blood pressure before pregnancy significantly reduce mortality risk to mother and child.
    Case summary: A 30-year-old woman with
    Discussion: This clinical case condenses several challenges encountered in the management of hypertension in women who plan to become pregnant. Firstly, it emphasizes the fact that secondary causes of chronic hypertension, including MAC, do not have to be overlooked in childbearing age patient. Secondly, it illustrates the need for a multidisciplinary analysis of all available treatment options in view of a future pregnancy. Finally, it discusses the particular follow-up and potential complications in pregnant women with MAC and aortic stent.
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytae092
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  2. Article ; Online: Multimodality imaging of cardiac B-cell lymphoma.

    Boscolo Berto, Martina / Spano, Giancarlo / Rhyner, Daniel / Huber, Adrian T / Gräni, Christoph

    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

    2022  Volume 30, Issue 3, Page(s) 1263–1265

    MeSH term(s) Humans ; Lymphoma, B-Cell ; Multimodal Imaging
    Language English
    Publishing date 2022-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1212505-2
    ISSN 1532-6551 ; 1071-3581
    ISSN (online) 1532-6551
    ISSN 1071-3581
    DOI 10.1007/s12350-022-02904-x
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    Zs.A 4121: Show issues Location:
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  3. Article ; Online: Chronic occluded coronary aneurysm as a complication of Kawasaki disease: a long-term follow-up.

    Peters, Alan A / Abbuehl, Heidi / Spano, Giancarlo / Graeni, Christoph / Huber, Adrian T

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2021  Volume 22, Issue 12, Page(s) e47–e48

    MeSH term(s) Adult ; Aftercare/methods ; Child ; Collateral Circulation/physiology ; Computed Tomography Angiography/methods ; Coronary Aneurysm/diagnosis ; Coronary Aneurysm/etiology ; Coronary Aneurysm/physiopathology ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/etiology ; Coronary Thrombosis/diagnostic imaging ; Coronary Thrombosis/etiology ; Diagnosis, Differential ; Diarrhea/diagnosis ; Diarrhea/etiology ; Humans ; Image Processing, Computer-Assisted ; Long Term Adverse Effects/cerebrospinal fluid ; Long Term Adverse Effects/etiology ; Long Term Adverse Effects/physiopathology ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Mucocutaneous Lymph Node Syndrome/physiopathology ; Mucocutaneous Lymph Node Syndrome/therapy ; Severity of Illness Index ; Vascular Calcification/diagnostic imaging ; Vomiting/diagnosis ; Vomiting/etiology
    Language English
    Publishing date 2021-08-27
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001244
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    Zs.A 5210: Show issues Location:
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    Zs.MO 559: Show issues

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  4. Article ; Online: Myocardial analysis from routine 4D cardiac-CT to predict reverse remodeling and clinical outcomes after transcatheter aortic valve implantation.

    Bernhard, Benedikt / Schütze, Jonathan / Leib, Zoe L / Spano, Giancarlo / Boscolo Berto, Martina / Bakula, Adam / Tomii, Daijiro / Shiri, Isaac / Brugger, Nicolas / De Marchi, Stefano / Reineke, David / Dobner, Stephan / Heg, Dik / Praz, Fabien / Lanz, Jonas / Stortecky, Stefan / Pilgrim, Thomas / Windecker, Stephan / Gräni, Christoph

    European journal of radiology

    2024  Volume 175, Page(s) 111425

    Abstract: Purpose: Our study aimed to determine whether 4D cardiac computed tomography (4DCCT) based quantitative myocardial analysis may improve risk stratification and can predict reverse remodeling (RRM) and mortality after transcatheter aortic valve ... ...

    Abstract Purpose: Our study aimed to determine whether 4D cardiac computed tomography (4DCCT) based quantitative myocardial analysis may improve risk stratification and can predict reverse remodeling (RRM) and mortality after transcatheter aortic valve implantation (TAVI).
    Methods: Consecutive patients undergoing clinically indicated 4DCCT prior to TAVI were prospectively enrolled. 4DCCT-derived left- (LV) and right ventricular (RV), and left atrial (LA) dimensions, mass, ejection fraction (EF) and myocardial strain were evaluated to predict RRM and survival. RRM was defined by either relative increase in LVEF by 5% or relative decline in LV end diastolic diameter (LVEDD) by 5% assessed by transthoracic echocardiography prior TAVI, at discharge, and at 12-month follow-up compared to baseline prior to TAVI.
    Results: Among 608 patients included in this study (55 % males, age 81 ± 6.6 years), RRM was observed in 279 (54 %) of 519 patients at discharge and in 218 (48 %) of 453 patients at 12-month echocardiography. While no CCT based measurements predicted RRM at discharge, CCT based LV mass index and LVEF independently predicted RRM at 12-month (OR
    Conclusion: Comprehensive myocardial functional information derived from routine 4DCCT in patients with severe aortic stenosis undergoing TAVI could predict reverse remodeling and clinical outcomes at 12-month following TAVI.
    Language English
    Publishing date 2024-03-13
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2024.111425
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    Zs.A 1630: Show issues Location:
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  5. Article: Cellulolytic bacteria joined with deproteinized whey decrease carbon to nitrogen ratio and improve stability of compost from wine production chain by-products

    Alfonzo, Antonio / Laudicina, Vito Armando / Muscarella, Sofia Maria / Badalucco, Luigi / Moschetti, Giancarlo / Spanò, Giacomo Massimo / Francesca, Nicola

    Journal of environmental management. 2022 Feb. 15, v. 304

    2022  

    Abstract: Composting residues from wine and dairy chains would contribute to increase the environmental sustainability of the production. The aim of this study was to evaluate the effects of deproteinized whey combined with bioactivators on the composting process. ...

    Abstract Composting residues from wine and dairy chains would contribute to increase the environmental sustainability of the production. The aim of this study was to evaluate the effects of deproteinized whey combined with bioactivators on the composting process. Bacillus velezensis and Kocuria rhizophila, bacteria with cellulolytic activity, were isolated from raw materials and inoculated in the organic mass to be composted. Piles moistened with deproteinized whey showed the highest reduction of total and dissolved organic carbon due to the stimulation of bacterial activity by nitrogen compounds held within deproteinized whey. Such findings were also confirmed by the speed up of the microbial carbon mineralization. Bioactivators and deproteinized whey speeded up the composting process and returned compost characterized by high stability and quality. The addition of available N is crucial to improve the composting process and can act even better if combined with cellulolytic bacteria.
    Keywords Bacillus velezensis ; Kocuria rhizophila ; carbon nitrogen ratio ; composts ; microbial activity ; microbial carbon ; mineralization ; nitrogen ; whey ; winemaking ; wines
    Language English
    Dates of publication 2022-0215
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2021.114194
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    Z 7556: Show issues

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  6. Article ; Online: Cellulolytic bacteria joined with deproteinized whey decrease carbon to nitrogen ratio and improve stability of compost from wine production chain by-products.

    Alfonzo, Antonio / Laudicina, Vito Armando / Muscarella, Sofia Maria / Badalucco, Luigi / Moschetti, Giancarlo / Spanò, Giacomo Massimo / Francesca, Nicola

    Journal of environmental management

    2021  Volume 304, Page(s) 114194

    Abstract: Composting residues from wine and dairy chains would contribute to increase the environmental sustainability of the production. The aim of this study was to evaluate the effects of deproteinized whey combined with bioactivators on the composting process. ...

    Abstract Composting residues from wine and dairy chains would contribute to increase the environmental sustainability of the production. The aim of this study was to evaluate the effects of deproteinized whey combined with bioactivators on the composting process. Bacillus velezensis and Kocuria rhizophila, bacteria with cellulolytic activity, were isolated from raw materials and inoculated in the organic mass to be composted. Piles moistened with deproteinized whey showed the highest reduction of total and dissolved organic carbon due to the stimulation of bacterial activity by nitrogen compounds held within deproteinized whey. Such findings were also confirmed by the speed up of the microbial carbon mineralization. Bioactivators and deproteinized whey speeded up the composting process and returned compost characterized by high stability and quality. The addition of available N is crucial to improve the composting process and can act even better if combined with cellulolytic bacteria.
    MeSH term(s) Bacteria ; Carbon ; Composting ; Dissolved Organic Matter ; Nitrogen ; Whey ; Wine
    Chemical Substances Dissolved Organic Matter ; Carbon (7440-44-0) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2021-12-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2021.114194
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  7. Article ; Online: Takotsubo Cardiomyopathy After mRNA COVID-19 Vaccination.

    Boscolo Berto, Martina / Spano, Giancarlo / Wagner, Benedikt / Bernhard, Benedikt / Häner, Jonas / Huber, Adrian T / Gräni, Christoph

    Heart, lung & circulation

    2021  Volume 30, Issue 12, Page(s) e119–e120

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; RNA, Messenger ; SARS-CoV-2 ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/etiology ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines ; RNA, Messenger
    Language English
    Publishing date 2021-07-15
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2021.06.521
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    Zs.A 4988: Show issues Location:
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  8. Article ; Online: Longitudinal evolution of ventricular function and cardiac magnetic resonance imaging tissue characteristics in tafamidis-treated transthyretin amyloid cardiomyopathy.

    Dobner, Stephan / Bernhard, Benedikt / Wieser, Monika / Wahl, Andreas / Stark, Anselm W / Köchli, Valentin / Spano, Giancarlo / Boscolo Berto, Martina / Johner, Caroline / Elchinova, Elena / Tanner, Giulin / Safarkhanlo, Yasaman / Stortecky, Stefan / Schütze, Jonathan / Hunziker Munsch, Lukas / Gräni, Christoph

    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

    2023  , Page(s) 1–3

    Language English
    Publishing date 2023-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1205246-2
    ISSN 1744-2818 ; 1350-6129
    ISSN (online) 1744-2818
    ISSN 1350-6129
    DOI 10.1080/13506129.2023.2284108
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    Zs.A 4114: Show issues Location:
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  9. Article ; Online: Delayed isolated peri-myocarditis in a Covid-19 patient with respiratory symptoms but without lung involvement.

    Spano, Giancarlo / Fischer, Kady / Maillat, Cédric / Vicario, Grégory / Huber, Adrian T / Gräni, Christoph

    The international journal of cardiovascular imaging

    2020  Volume 36, Issue 11, Page(s) 2279–2280

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Myocarditis/complications ; Myocarditis/diagnostic imaging ; Myocarditis/physiopathology ; Pandemics ; Pleural Effusion/complications ; Pleural Effusion/diagnostic imaging ; Pleural Effusion/physiopathology ; Pneumonia, Viral/complications ; Predictive Value of Tests ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-020-01943-0
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    Zs.A 2104: Show issues Location:
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  10. Article ; Online: Microbial-based Biocontrol Solutions for Fruits and Vegetables: Recent Insight, Patents, and Innovative Trends.

    De Simone, Nicola / Capozzi, Vittorio / Amodio, Maria Luisa / Colelli, Giancarlo / Spano, Giuseppe / Russo, Pasquale

    Recent patents on food, nutrition & agriculture

    2021  Volume 12, Issue 1, Page(s) 3–18

    Abstract: Background: Fruits and vegetables are susceptible to colonisation by undesired microflora, which, in pre- and post-harvest conditions, negatively impact the quality of these products, leading to a reduction of yield, shelf-life, and marketability. In ... ...

    Abstract Background: Fruits and vegetables are susceptible to colonisation by undesired microflora, which, in pre- and post-harvest conditions, negatively impact the quality of these products, leading to a reduction of yield, shelf-life, and marketability. In the few last years, the use of microbial Biological Control Agents (BCAs) has assumed international relevance in order to control harmful microorganisms, as a promising alternative to chemical interventions.
    Objective: The purpose of this review is to discuss the microbial-based solutions applicable for the biocontrol of the main microbial spoilers, phytopathogens, and human food-borne pathogens affecting fruits and vegetables during their production and storage.
    Results: A comprehensive overview of the scientific literature investigating the effectiveness of BCA-based products available on the market is provided, as well as of the most recent patents protecting biotechnological applications in this field. Innovative trends are discussed, with a particular focus on the integration of BCAs to minimise spoilage phenomena and microbiological risks adopting combined approaches.
    Conclusion: This study underlines the growing interest about biocontrol strategies to counteract the growth of spoilage and/or pathogenic microorganisms indicating that in the next years a considerable increase of commercial products and patents will be developed worldwide to exploit innovative biotechnological solutions in the sector.
    MeSH term(s) Antibiosis ; Bacteria/drug effects ; Bacterial Physiological Phenomena ; Biological Control Agents/pharmacology ; Food Preservation/instrumentation ; Food Preservation/legislation & jurisprudence ; Food Preservation/methods ; Fruit/chemistry ; Fruit/microbiology ; Fungi/drug effects ; Fungi/physiology ; Patents as Topic ; Plant Diseases/microbiology ; Plant Diseases/prevention & control ; Vegetables/chemistry ; Vegetables/microbiology
    Chemical Substances Biological Control Agents
    Language English
    Publishing date 2021-02-06
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2486959-4
    ISSN 1876-1429 ; 2212-7984
    ISSN (online) 1876-1429
    ISSN 2212-7984
    DOI 10.2174/2212798412666210125141117
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