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Article: Assessing the Correlation Between Patient-Specific Characteristics and Braden Pressure Injury Risk Score at a Suburban Tertiary Hospital in Nigeria.

Salawu, Adedayo I / Ipinnimo, Tope M / Bamidele, Tolulope A / Babalola, Olakunle F / Okunlola, Cecilia K / Adeleye, Maryam O / Nkereuwem, Precious E

Cureus

2023 Volume 15, Issue 5, Page(s) e39373

Abstract: ... patients' age (r=-0.353, R=12.5%, p<0.001), pre-admission occupation (F=10.290, p<0.001) as well as the ward ... of admission (F=11.915, p<0.001). However, gender and social support were not significantly associated ...

Abstract	Background and objective Pressure injury (PI) is a frequent complication of hospital admissions, and it increases healthcare costs, morbidity, and mortality. This study aimed to use the Braden scale to assess the PI risk among hospitalized patients without PI and determine its association with patient-specific factors. Methods A cross-sectional study was conducted at a suburban tertiary hospital involving a total of 211 hospitalized patients recruited during the study period (October 2022). Patients were assessed using the Braden scale and their sociodemographic data were also recorded. Data analysis was performed using IBM SPSS Statistics version 26.0 (IBM Corp., Armonk, NY). Results The mean age of the patients was 41.8 ±23.0 years and 54.0% of the patients were females. The average Braden score of the patients was 19.01 ±3.42, and more than half (58.3%) of the patients showed no risk while only 0.9% of the patients had a severe risk of PI. There was a statistically significant association between PI risk and patients' age (r=-0.353, R=12.5%, p<0.001), pre-admission occupation (F=10.290, p<0.001) as well as the ward of admission (F=11.915, p<0.001). However, gender and social support were not significantly associated. Conclusion The age, pre-admission occupation, and ward of admission of patients were found to be significantly associated with the risk of developing PI. It is recommended that more resources be channeled toward preventing PI among high-risk patients in resource-limited settings.
Language	English
Publishing date	2023-05-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.39373
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Article ; Online: Perfluorooctanoic acid dominates the molecular-level effects of a mixture of equal masses of perfluorooctanoic acid and perfluorooctane sulfonic acid in earthworm.

Han, Ziwei / Oyeyemi, Bolaji F / Zenobio, Jenny E / Salawu, Omobayo A / Adeleye, Adeyemi S

Journal of hazardous materials

2023 Volume 457, Page(s) 131718

Abstract: ... distribution coefficient (K ...

Abstract	Per- and polyfluoroalkyl substances (PFAS) are an important class of emerging contaminants in the environment. Most studies on the impact of PFAS mixtures considered phenotypic endpoints, which may not adequately reflect the sublethal effects on organisms. To fill this knowledge gap, we investigated the subchronic impact of environmentally relevant concentrations of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS)-as individual compounds and a mixture (PFOS+PFOA)-on earthworm (Eisenia fetida), using phenotypic and molecular endpoints. PFAS decreased the survival (12.2-16.3%), biomass (9.0-9.8%), and reproduction (15.6-19.8%) of E. fetida after 28 d of exposure. The bioaccumulation of PFOS after 28 d increased (from 2790.7 ng/g-dw to 5224.9 ng/g-dw) while that of PFOA decreased (from 780.2 ng/g-dw to 280.5 ng/g-dw) when E. fetida was exposed to the mixture compared to the individual compounds. These bioaccumulation trends were partly attributed to changes in the soil distribution coefficient (K
MeSH term(s)	Animals ; Oligochaeta/metabolism ; Alkanesulfonic Acids/toxicity ; Alkanesulfonic Acids/metabolism ; Caprylates/toxicity ; Caprylates/metabolism ; Fluorocarbons/toxicity ; Fluorocarbons/metabolism
Chemical Substances	perfluorooctane sulfonic acid (9H2MAI21CL) ; perfluorooctanoic acid (947VD76D3L) ; Alkanesulfonic Acids ; Caprylates ; Fluorocarbons
Language	English
Publishing date	2023-05-26
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2023.131718
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Article ; Online: Health workforce incentives and dis-incentives during the COVID-19 pandemic: experiences from Democratic Republic of Congo, Nigeria, Senegal, and Uganda.

BMC health services research

2024 Volume 24, Issue 1, Page(s) 422

Abstract: Background: The COVID-19 pandemic presented a myriad of challenges for the health workforce around the world due to its escalating demand on service delivery. A motivated health workforce is critical to effectual emergency response and in some settings, ...

Abstract	Background: The COVID-19 pandemic presented a myriad of challenges for the health workforce around the world due to its escalating demand on service delivery. A motivated health workforce is critical to effectual emergency response and in some settings, incentivizing health workers motivates them and ensures continuity in the provision of health services. We describe health workforce experiences with incentives and dis-incentives during the COVID-19 response in the Democratic Republic of Congo (DRC), Senegal, Nigeria, and Uganda. Methods: This is a multi-country qualitative research study involving four African countries namely: DRC, Nigeria, Senegal, and Uganda which assessed the workplace incentives instituted in response to the COVID-19 pandemic. Key informant interviews (n = 60) were conducted with staff at ministries of health, policy makers and health workers. Interviews were virtual using the telephone or Zoom. They were audio recorded, transcribed verbatim, and analyzed thematically. Themes were identified and quotes were used to support findings. Results: Health worker incentives included (i) financial rewards in the form of allowances and salary increments. These motivated health workers, sustaining the health system and the health workers' efforts during the COVID-19 response across the four countries. (ii) Non-financial incentives related to COVID-19 management such as provision of medicines/supplies, on the job trainings, medical care for health workers, social welfare including meals, transportation and housing, recognition, health insurance, psychosocial support, and supervision. Improvised determination and distribution of both financial and non-financial incentives were common across the countries. Dis-incentives included the lack of personal protective equipment, lack of transportation to health facilities during lockdown, long working hours, harassment by security forces and perceived unfairness in access to and inadequacy of financial incentives. Conclusion: Although important for worker motivation, financial and non-financial incentives generated some dis-incentives because of the perceived unfairness in their provision. Financial and non-financial incentives deployed during health emergencies should preferably be pre-determined, equitably and transparently provided because when arbitrarily applied, these same financial and non-financial incentives can potentially become dis-incentives. Moreover, financial incentives are useful only as far as they are administered together with non-financial incentives such as supportive and well-resourced work environments. The potential negative impacts of interventions such as service delivery re-organization and lockdown within already weakened systems need to be anticipated and due precautions exercised to reduce dis-incentives during emergencies.
MeSH term(s)	Humans ; Motivation ; COVID-19/epidemiology ; Health Workforce ; Nigeria/epidemiology ; Democratic Republic of the Congo/epidemiology ; Senegal ; Uganda/epidemiology ; Pandemics ; Emergencies ; Communicable Disease Control
Language	English
Publishing date	2024-04-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-024-10822-6
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Article ; Online: Spread and seasonality of COVID-19 pandemic confirmed cases in sub-Saharan Africa: experience from Democratic Republic of Congo, Nigeria, Senegal, and Uganda.

BMC infectious diseases

2023 Volume 23, Issue 1, Page(s) 187

Abstract: Background: The COVID-19 pandemic has impacted the world negatively with huge health and socioeconomic consequences. This study estimated the seasonality, trajectory, and projection of COVID-19 cases to understand the dynamics of the disease spread and ... ...

Abstract	Background: The COVID-19 pandemic has impacted the world negatively with huge health and socioeconomic consequences. This study estimated the seasonality, trajectory, and projection of COVID-19 cases to understand the dynamics of the disease spread and inform response interventions. Method: Descriptive analysis of daily confirmed COVID-19 cases from January 2020 to 12 Results: Nigeria had the highest rate of spread (β) of COVID-19 (β = 381.2) while DRC had the least rate (β = 119.4). DRC, Uganda, and Senegal had a similar pattern of COVID-19 spread from the onset through December 2020. The average doubling time in COVID-19 case count was highest in Uganda (148 days) and least in Nigeria (83 days). A seasonal variation was found in the COVID-19 data for all four countries but the timing of the cases showed some variations across countries. More cases are expected in the 1 Conclusion: Our findings show a seasonality that may warrant consideration for COVID-19 periodic interventions in the peak seasons in the preparedness and response strategies.
MeSH term(s)	Humans ; Uganda/epidemiology ; COVID-19/epidemiology ; Nigeria/epidemiology ; Senegal/epidemiology ; Democratic Republic of the Congo/epidemiology ; Pandemics
Language	English
Publishing date	2023-03-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-023-08168-1
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Article: Percutanous vertebroplasty for vertebral compression fracture in geriatric patients; a report of two cases.

Diamond, Tamunokuro E / Ogbu, Valentine / Ekwe, Kingsley / Ogedegbe, Felix / Salawu, Siddiq

Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria

2018 Volume 25, Issue 2, Page(s) 189–191

MeSH term(s)	Fractures, Compression ; Humans ; Pain Measurement ; Spinal Fractures ; Vertebroplasty
Language	English
Publishing date	2018-06-25
Publishing country	Nigeria
Document type	Case Reports ; Journal Article
ISSN	1115-2613
ISSN	1115-2613
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Article ; Online: Private sector engagement in the COVID-19 response: experiences and lessons from the Democratic Republic of Congo, Nigeria, Senegal and Uganda.

Kabwama, Steven N / Kiwanuka, Suzanne N / Mapatano, Mala Ali / Fawole, Olufunmilayo I / Seck, Ibrahima / Namale, Alice / Ndejjo, Rawlance / Kizito, Susan / Monje, Fred / Bosonkie, Marc / Egbende, Landry / Bello, Segun / Bamgboye, Eniola A / Dairo, Magbagbeola D / Adebowale, Ayo S / Salawu, Mobolaji M / Afolabi, Rotimi F / Diallo, Issakha / Leye, Mamadou M M /

Ndiaye, Youssou / Fall, Mane / Bassoum, Oumar / Alfvén, Tobias / Sambisa, William / Wanyenze, Rhoda K

Globalization and health

2022 Volume 18, Issue 1, Page(s) 60

Abstract: Background: Private entities play a major role in health globally. However, their contribution has not been fully optimized to strengthen delivery of public health services. The COVID-19 pandemic has overwhelmed health systems and precipitated ... ...

Abstract	Background: Private entities play a major role in health globally. However, their contribution has not been fully optimized to strengthen delivery of public health services. The COVID-19 pandemic has overwhelmed health systems and precipitated coalitions between public and private sectors to address critical gaps in the response. We conducted a study to document the public and private sector partnerships and engagements to inform current and future responses to public health emergencies. Methods: This was a multi-country cross-sectional study conducted in the Democratic Republic of Congo, Nigeria, Senegal and Uganda between November 2020 and March 2021 to assess responses to the COVID-19 pandemic. We conducted a scoping literature review and key informant interviews (KIIs) with private and public health sector stakeholders. The literature reviewed included COVID-19 country guidelines and response plans, program reports and peer-reviewed and non-peer-reviewed publications. KIIs elicited information on country approaches and response strategies specifically the engagement of the private sector in any of the strategic response operations. Results: Across the 4 countries, private sector strengthened laboratory systems, COVID-19 case management, risk communication and health service continuity. In the DRC and Nigeria, private entities supported contact tracing and surveillance activities. Across the 4 countries, the private sector supported expansion of access to COVID-19 testing services through establishing partnerships with the public health sector albeit at unregulated fees. In Senegal and Uganda, governments established partnerships with private sector to manufacture COVID-19 rapid diagnostic tests. The private sector also contributed to treatment and management of COVID-19 cases. In addition, private entities provided personal protective equipment, conducted risk communication to promote adherence to safety procedures and health promotion for health service continuity. However, there were concerns related to reporting, quality and cost of services, calling for quality and price regulation in the provision of services. Conclusions: The private sector contributed to the COVID-19 response through engagement in COVID-19 surveillance and testing, management of COVID-19 cases, and health promotion to maintain health access. There is a need to develop regulatory frameworks for sustainable public-private engagements including regulation of pricing, quality assurance and alignment with national plans and priorities during response to epidemics.
MeSH term(s)	COVID-19/epidemiology ; COVID-19 Testing ; Cross-Sectional Studies ; Democratic Republic of the Congo/epidemiology ; Humans ; Nigeria/epidemiology ; Pandemics ; Private Sector ; Senegal/epidemiology ; Uganda/epidemiology
Language	English
Publishing date	2022-06-15
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2185774-X
ISSN	1744-8603 ; 1744-8603
ISSN (online)	1744-8603
ISSN	1744-8603
DOI	10.1186/s12992-022-00853-1
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Article ; Online: STEPFORWARD study: a randomised controlled feasibility trial of a self-aligning prosthetic ankle-foot for older patients with vascular-related amputations.

Vanicek, Natalie / Coleman, Elizabeth / Watson, Judith / Bell, Kerry / McDaid, Catriona / Barnett, Cleveland / Twiste, Martin / Jepson, Fergus / Salawu, Abayomi / Harrison, Dennis / Mitchell, Natasha

BMJ open

2021 Volume 11, Issue 3, Page(s) e045195

Abstract: Objectives: To determine the feasibility of conducting a full-scale randomised controlled trial (RCT) of the effectiveness and cost-effectiveness of a self-aligning prosthetic ankle-foot compared with a standard prosthetic ankle-foot.: Design: ... ...

Abstract	Objectives: To determine the feasibility of conducting a full-scale randomised controlled trial (RCT) of the effectiveness and cost-effectiveness of a self-aligning prosthetic ankle-foot compared with a standard prosthetic ankle-foot. Design: Multicentre parallel group feasibility RCT. Setting: Five prosthetics centres in England recruiting from July 2018 to August 2019. Participants: Adults aged ≥50 years with a vascular-related or non-traumatic transtibial amputation for 1 year or longer, categorised as having 'limited community mobility' and using a non-self-aligning ankle-foot. Intervention: Participants were randomised into one of two groups for 12 weeks: self-aligning prosthetic ankle-foot or existing non-self-aligning prosthetic ankle-foot. Outcomes: Feasibility measures: recruitment, consent and retention rates; and completeness of questionnaire and clinical assessment datasets across multiple time points. Feasibility of collecting daily activity data with wearable technology and health resource use data with a bespoke questionnaire. Results: Fifty-five participants were randomised (61% of the target 90 participants): n=27 self-aligning ankle-foot group, n=28 non-self-aligning ankle-foot group. Fifty-one participants were included in the final analysis (71% of the target number of participants). The consent rate and retention at final follow-up were 86% and 93%, respectively. The average recruitment rate was 1.25 participants/site/month (95% CI 0.39 to 2.1). Completeness of questionnaires ranged from 89%-94%, and clinical assessments were 92%-95%, including the activity monitor data. The average completion rates for the EQ-5D-5L and bespoke resource use questionnaire were 93% and 63%, respectively. Conclusions: This feasibility trial recruited and retained participants who were categorised as having 'limited community mobility' following a transtibial amputation. The high retention rate of 93% indicated the trial was acceptable to participants and feasible to deliver as a full-scale RCT. The findings support a future, fully powered evaluation of the effectiveness and cost-effectiveness of a self-aligning prosthetic ankle-foot compared with a standard non-self-aligning version with some adjustments to the trial design and delivery. Trial registration number: ISRCTN15043643.
MeSH term(s)	Activities of Daily Living ; Adult ; Amputation ; Ankle ; Cost-Benefit Analysis ; England ; Feasibility Studies ; Humans ; Middle Aged
Language	English
Publishing date	2021-03-18
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2020-045195
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Article: Helicobacter pylori indyspeptic Nigerians.

Olokoba, A B / Apari, E / Salawu, F K / Nggada, H A

West African journal of medicine

2013 Volume 32, Issue 4, Page(s) 277–280

Abstract: Background: Dyspepsia is a common gastrointestinal disorder, and is the most common indication for upper gastrointestinal endoscopy. Helicobacter pylori is a significant aetiological factor in acid peptic diseases and gastric cancer. Detection of this ... ...

Abstract	Background: Dyspepsia is a common gastrointestinal disorder, and is the most common indication for upper gastrointestinal endoscopy. Helicobacter pylori is a significant aetiological factor in acid peptic diseases and gastric cancer. Detection of this organism during upper gastrointestinal endoscopy has become standard clinical practice. Data is scanty from North-Eastern Nigeria on the subject. Objectives: To determine the prevalence of Helicobacter pylori among dyspeptic patients, and alsoto find out the association of H. pylori and degree of activity in chronic gastritis. Methods: This is a hospital-based cross sectional study which was carried out at the Endoscopy unit of Federal Medical Centre, Yola and Histopathology unit, University of Maiduguri Teaching Hospital, Maiduguri from November, 2006 to May, 2010. Patients with dyspepsia who underwent upper gastrointestinal endoscopy as part of their work-up, also had endoscopic biopsies taken from the antral portions of their stomach. The biopsy specimens were fixed in 10% formalin and transported from Yola to Maiduguri by courier for processing. Results: Three hundred and forty-nine patients comprising 152(43.6%) males and 197(56.4%) females with dyspepsia had upper gastrointestinal endoscopy. Their age ranged between 14 and 103 years with a median of 44.1 years. A prevalence rate of 56.7% for Helicobacter pylori was found.Helicobacter pylori associated with severe activity accounted for 80.3%; moderate activity- 57.5%; mild activity - 20% and normal gastric mucosa- 9.1%. Conclusion: There is a high prevalence of Helicobacter pylori among patients with dyspepsia, and a strong association between H. pylori and chronic gastritis with severe activity.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chronic Disease ; Cross-Sectional Studies ; Dyspepsia/microbiology ; Female ; Gastritis/microbiology ; Helicobacter Infections/epidemiology ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Nigeria ; Prevalence ; Young Adult
Language	French
Publishing date	2013-10
Publishing country	Nigeria
Document type	Journal Article
ZDB-ID	1132088-6
ISSN	0189-160X
ISSN	0189-160X
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Article ; Online: Priapism resulting from sertralinerisperidone combination in a 30-year-old Nigerian man with schizophrenia.

Salawu, F K / Mustapha, H / Danburam, A

Annals of African medicine

2010 Volume 9, Issue 3, Page(s) 195

MeSH term(s)	Adult ; Antidepressive Agents/adverse effects ; Antipsychotic Agents/adverse effects ; Drug Therapy, Combination ; Humans ; Male ; Priapism/chemically induced ; Risperidone/adverse effects ; Schizophrenia/drug therapy ; Sertraline/adverse effects
Chemical Substances	Antidepressive Agents ; Antipsychotic Agents ; Risperidone (L6UH7ZF8HC) ; Sertraline (QUC7NX6WMB)
Language	English
Publishing date	2010-07
Publishing country	India
Document type	Case Reports ; Letter
ZDB-ID	2165792-0
ISSN	0975-5764 ; 1596-3519
ISSN (online)	0975-5764
ISSN	1596-3519
DOI	10.4103/1596-3519.68349
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Article: Non-motor symptoms of Parkinson's disease: diagnosis and management.

Salawu, F K / Danburam, A / Olokoba, A B

Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria

2010 Volume 19, Issue 2, Page(s) 126–131

Abstract: Background: Non-motor symptoms (NMS) of Parkinson's disease (PD) are a key determinant of health, quality of life (QoL) and societal cost of PD. They are often less appreciated than motor symptoms but are important sources of disability for many PD ... ...

Abstract	Background: Non-motor symptoms (NMS) of Parkinson's disease (PD) are a key determinant of health, quality of life (QoL) and societal cost of PD. They are often less appreciated than motor symptoms but are important sources of disability for many PD patients. Methods: Literature search was performed using the reference databases Medline, Science Citation Index and EMBASE. The keywords used were 'non-motor symptoms', Parkinson's disease, olfaction and constipation. Papers discovered by this search were reviewed, as were references cited therein. Results: Contrary to common perception, many NMS of PD occur early in PD and some may even predate the diagnosis of PD that is based on motor signs. These include olfactory deficit, sleep problems such as rapid eye movement behaviour disorder, constipation and the more recently described male erectile dysfunction. Conclusion: There is compelling evidence that non-motor symptoms of PD play a dominant role in the QoL and disability of PD patients and the QoL of their 'informal' carers. Effective clinical management of PD therefore demands that these symptoms be identified and to the extent possible treated.
MeSH term(s)	Autonomic Nervous System Diseases/diagnosis ; Autonomic Nervous System Diseases/etiology ; Autonomic Nervous System Diseases/therapy ; Behavioral Symptoms/diagnosis ; Behavioral Symptoms/etiology ; Behavioral Symptoms/therapy ; Cognition Disorders/diagnosis ; Cognition Disorders/etiology ; Cognition Disorders/therapy ; Constipation/diagnosis ; Constipation/etiology ; Constipation/therapy ; Dopamine Agents/therapeutic use ; Erectile Dysfunction/diagnosis ; Erectile Dysfunction/etiology ; Erectile Dysfunction/therapy ; Health Status ; Humans ; Male ; Olfaction Disorders/diagnosis ; Olfaction Disorders/etiology ; Olfaction Disorders/therapy ; Parkinson Disease/complications ; Parkinson Disease/physiopathology ; Parkinson Disease/psychology ; Quality of Life ; Sleep Wake Disorders/diagnosis ; Sleep Wake Disorders/etiology ; Sleep Wake Disorders/therapy
Chemical Substances	Dopamine Agents
Language	English
Publishing date	2010-06-21
Publishing country	Nigeria
Document type	Journal Article ; Review
ISSN	1115-2613
ISSN	1115-2613
DOI	10.4314/njm.v19i2.56496
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