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  1. Article ; Online: In-Ovo injection of melittin into Alexandria chicken eggs: a way for early immune acceleration.

    Khalil, Mohamed H / Hassan, Saber S / Soliman, Farid N K / Hassan, Mohamed I

    Animal biotechnology

    2023  Volume 34, Issue 8, Page(s) 4060–4068

    Abstract: This study intended to assess the properties of in-ovo administration of Melittin (MLT) on hatchability, chick yield, hematology, immunological indices and relative organs weight of Alexandria chickens at hatch. A total of 600 eggs with an average weight ...

    Abstract This study intended to assess the properties of in-ovo administration of Melittin (MLT) on hatchability, chick yield, hematology, immunological indices and relative organs weight of Alexandria chickens at hatch. A total of 600 eggs with an average weight of (45.12 g), were gathered and split into five groups: a non-injected group or negative control (NC), a saline injection group or positive control (PC), and three concentrations of MLT (5, 10 and 15 µg of MLT per egg, respectively). On day 18 of incubation, eggs from the injection groups were injected into the amniotic fluid from the large end with the in-ovo injection solutions (0.2 ml per egg). Results indicated that 10 µg MLT/egg positively affected the weight and yield of chicks. In addition, our findings indicated that the in-ovo administration with 10 or 15 µg MLT/egg was superior in most of the immunological indicators (spleen and bursa relative weights, immunoglobulins IgG and IgM, T cells and B cells). In conclusion, in order to improve the immune efficiency (early immune acceleration) of Alexandria chicks, which may contribute to offering a significant boost to their future performance, this study suggests injecting eggs with 5 or 10 µg MLT/egg.
    MeSH term(s) Animals ; Chickens ; Melitten/pharmacology ; Injections/veterinary ; Ovum
    Chemical Substances Melitten (20449-79-0)
    Language English
    Publishing date 2023-09-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2043243-4
    ISSN 1532-2378 ; 1049-5398
    ISSN (online) 1532-2378
    ISSN 1049-5398
    DOI 10.1080/10495398.2023.2255063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The use of thermal imaging for evaluation of peripheral tissue perfusion in surgical patients with septic shock.

    Hasanin, Ahmed / Fekry, Radwa / Mostafa, Maha / Kasem, Sahar / Eissa, Amany / Mohamed, Hassan / Raafat, Heba

    BMC anesthesiology

    2024  Volume 24, Issue 1, Page(s) 109

    Abstract: ... in (Celsius [°C]) were assessed at the time of admission, 6- and 12 h after admission. The canthal-toe and ... significant accuracy in predicting mortality at any timepoint. Only the toe temperature measurement at 12 h ... predictive values (> 90%) at cut-off value of > 2.5-4.3 mmol/L for the serum lactate and > 3-4.2 s ...

    Abstract Background: In this study, we aimed to evaluate the ability of central-to-peripheral temperature gradients using thermal imaging to predict in-hospital mortality in surgical patients with septic shock.
    Methods: This prospective observational study included adult patients with septic shock admitted to the intensive care unit postoperatively. Serum lactate (in mmol/L), capillary refill time (CRT) (in seconds), toe (peripheral) and canthal (central) temperature by infrared thermography and the corresponding room temperature in (Celsius [°C]) were assessed at the time of admission, 6- and 12 h after admission. The canthal-toe and room-toe temperature gradients were calculated. According to their final outcomes, patients were divided into survivors and non-survivors. The ability of canthal-toe temperature gradient (primary outcome), room-toe temperature gradient, toe temperature, serum lactate and CRT, measured at the prespecified timepoints to predict in-hospital mortality was analyzed using the area under receiver operating characteristic curve (AUC).
    Results: Fifty-six patients were included and were available for the final analysis and 41/56 (73%) patients died. The canthal-toe and room-toe temperature gradients did not show significant accuracy in predicting mortality at any timepoint. Only the toe temperature measurement at 12 h showed good ability in predicting in-hospital mortality with AUC (95% confidence interval) of 0.72 (0.58-0.84) and a negative predictive value of 70% at toe temperature of ≤ 25.5 °C. Both serum lactate and CRT showed good ability to predict in-hospital mortality at all timepoints with high positive predictive values (> 90%) at cut-off value of > 2.5-4.3 mmol/L for the serum lactate and > 3-4.2 s for the CRT.
    Conclusion: In post-operative emergency surgical patients with septic shock, high serum lactate and CRT can accurately predict in-hospital mortality and were superior to thermal imaging, especially in the positive predictive values. Toe temperature > 25.5 °C, measured using infrared thermal imaging can exclude in-hospital mortality with a negative predictive value of 70%.
    MeSH term(s) Adult ; Humans ; Shock, Septic ; Prognosis ; ROC Curve ; Lactates ; Perfusion
    Chemical Substances Lactates
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-024-02486-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Efficiency of

    Elsharkawy, Mohsen Mohamed / Almasoud, Mustafa / Alsulaiman, Yasser Mohamed / Baeshen, Rowida S / Elshazly, Hayam / Kadi, Roqayah H / Hassan, Mohamed M / Shawer, Rady

    Insects

    2022  Volume 13, Issue 10

    Abstract: The Red Palm Weevil ( ...

    Abstract The Red Palm Weevil (
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects13100905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Novel

    Dawood, Kamal M / Raslan, Mohamed A / Abbas, Ashraf A / Mohamed, Belal E / Abdellattif, Magda H / Nafie, Mohamed S / Hassan, Mohamed K

    Frontiers in chemistry

    2021  Volume 9, Page(s) 694870

    Abstract: ... A series ... ...

    Abstract A series of
    Language English
    Publishing date 2021-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2021.694870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Formulation and evaluation of azithromycin-loaded silver nanoparticles for the treatment of infected wounds.

    Saddik, Mohammed S / Al-Hakkani, Mostafa F / Abu-Dief, Ahmed M / Mohamed, Mohamed S / Al-Fattah, Islam A / Makki, Mahmoud / El-Mokhtar, Mohamed A / Sabet, Marwa A / Amin, M S / Ahmed, Hoda A / Al-Ghamdi, Khalaf / Mohammad, Mostafa K / Hassan, Mohammad H A

    International journal of pharmaceutics: X

    2024  Volume 7, Page(s) 100245

    Abstract: Infected wounds pose a significant challenge in healthcare, requiring innovative therapeutic strategies. Therefore, there is a critical need for innovative pharmaceutical materials to improve wound healing and combat bacterial growth. This study examined ...

    Abstract Infected wounds pose a significant challenge in healthcare, requiring innovative therapeutic strategies. Therefore, there is a critical need for innovative pharmaceutical materials to improve wound healing and combat bacterial growth. This study examined the efficacy of azithromycin-loaded silver nanoparticles (AZM-AgNPs) in treating infected wounds. AgNPs synthesized using a green method with
    Language English
    Publishing date 2024-04-09
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1567
    ISSN (online) 2590-1567
    DOI 10.1016/j.ijpx.2024.100245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rapid and sensitive in situ detection of heavy metals in fish using enhanced Raman spectroscopy.

    Hassan, Amal H A / Zeinhom, Mohamed M A / Shaban, Mohamed / Korany, Ahmed M / Gamal, Ahmed / Abdel-Atty, Nasser S / Al-Saeedi, Sameerah I

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Volume 313, Page(s) 124082

    Abstract: Heavy metals have been widely applied in industry, agriculture, and other fields because of their outstanding physics and chemistry properties. They are non-degradable even at low concentrations, causing irreversible harm to the human and other organisms. ...

    Abstract Heavy metals have been widely applied in industry, agriculture, and other fields because of their outstanding physics and chemistry properties. They are non-degradable even at low concentrations, causing irreversible harm to the human and other organisms. Therefore, it is of great significance to develop high accuracy and sensitivity as well as stable techniques for their detection. Raman scattering spectroscopy and atomic absorption spectrophotometer (AAS) were used parallelly to detect heavy metal ions such as Hg, Cd, and Pb of different concentrations in fish samples. The concentration of the heavy metals is varied from 5 ppb to 5 ppm. Despite the satisfactory recoveries of AAS, their drawbacks are imperative for an alternative technique. In Raman scattering spectroscopy, the intensities and areas of the characteristic peaks are increased with increasing the concentration of the heavy metals. For Hg concentration ≥ 1 ppm, a slight shift is observed in the peak position. The obtained values of peak intensity and peak area are modeled according to Elvoich, Pseudo-first order, Pseudo-second order, and asymptotic1 exponential model. The best modeling was obtained using the Elovich model followed by the asymptotic1 exponential model. The introduced Raman spectroscopy-based approach for on-site detection of trace heavy metal pollution in fish samples is rapid, low-cost, and simple to implement, increasing its visibility in food safety and industrial applications.
    MeSH term(s) Animals ; Humans ; Spectrum Analysis, Raman ; Metals, Heavy/analysis ; Mercury/analysis ; Fishes ; Environmental Pollution ; Cadmium/analysis ; Environmental Monitoring
    Chemical Substances Metals, Heavy ; Mercury (FXS1BY2PGL) ; Cadmium (00BH33GNGH)
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2024.124082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Differential Impact of Massachusetts, Canadian 4/91, and California (Cal) 1737 Genotypes of Infectious Bronchitis Virus Infection on Lymphoid Organs of Chickens.

    Abd-Elsalam, Reham M / Najimudeen, Shahnas M / Mahmoud, Motamed E / Hassan, Mohamed S H / Gallardo, Rodrigo A / Abdul-Careem, Mohamed Faizal

    Viruses

    2024  Volume 16, Issue 3

    Abstract: Infectious bronchitis virus (IBV) induces severe economic losses in chicken farms due to the emergence of new variants leading to vaccine breaks. The studied IBV strains belong to Massachusetts (Mass), Canadian 4/91, and California (Cal) 1737 genotypes ... ...

    Abstract Infectious bronchitis virus (IBV) induces severe economic losses in chicken farms due to the emergence of new variants leading to vaccine breaks. The studied IBV strains belong to Massachusetts (Mass), Canadian 4/91, and California (Cal) 1737 genotypes that are prevalent globally. This study was designed to compare the impact of these three IBV genotypes on primary and secondary lymphoid organs. For this purpose, one-week-old specific pathogen-free chickens were inoculated with Mass, Canadian 4/91, or Cal 1737 IBV variants, keeping a mock-infected control. We examined the IBV replication in primary and secondary lymphoid organs. The molecular, histopathological, and immunohistochemical examinations revealed significant differences in lesion scores and viral distribution in these immune organs. In addition, we observed B-cell depletion in the bursa of Fabricius and the spleen with a significant elevation of T cells in these organs. Further studies are required to determine the functional consequences of IBV replication in lymphoid organs.
    MeSH term(s) Animals ; Canada ; Chickens ; Infectious bronchitis virus/genetics ; Coronavirus Infections ; Poultry Diseases ; California ; Genotype ; Massachusetts ; Viral Vaccines
    Chemical Substances Viral Vaccines
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16030326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Enhanced gorilla troops optimizer powered by marine predator algorithm: global optimization and engineering design.

    Hassan, Mohamed H / Kamel, Salah / Mohamed, Ali Wagdy

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7650

    Abstract: This study presents an advanced metaheuristic approach termed the Enhanced Gorilla Troops Optimizer (EGTO), which builds upon the Marine Predators Algorithm (MPA) to enhance the search capabilities of the Gorilla Troops Optimizer (GTO). Like numerous ... ...

    Abstract This study presents an advanced metaheuristic approach termed the Enhanced Gorilla Troops Optimizer (EGTO), which builds upon the Marine Predators Algorithm (MPA) to enhance the search capabilities of the Gorilla Troops Optimizer (GTO). Like numerous other metaheuristic algorithms, the GTO encounters difficulties in preserving convergence accuracy and stability, notably when tackling intricate and adaptable optimization problems, especially when compared to more advanced optimization techniques. Addressing these challenges and aiming for improved performance, this paper proposes the EGTO, integrating high and low-velocity ratios inspired by the MPA. The EGTO technique effectively balances exploration and exploitation phases, achieving impressive results by utilizing fewer parameters and operations. Evaluation on a diverse array of benchmark functions, comprising 23 established functions and ten complex ones from the CEC2019 benchmark, highlights its performance. Comparative analysis against established optimization techniques reveals EGTO's superiority, consistently outperforming its counterparts such as tuna swarm optimization, grey wolf optimizer, gradient based optimizer, artificial rabbits optimization algorithm, pelican optimization algorithm, Runge Kutta optimization algorithm (RUN), and original GTO algorithms across various test functions. Furthermore, EGTO's efficacy extends to addressing seven challenging engineering design problems, encompassing three-bar truss design, compression spring design, pressure vessel design, cantilever beam design, welded beam design, speed reducer design, and gear train design. The results showcase EGTO's robust convergence rate, its adeptness in locating local/global optima, and its supremacy over alternative methodologies explored.
    MeSH term(s) Animals ; Humans ; Rabbits ; Gorilla gorilla ; Algorithms ; Data Compression ; Alaska Natives ; Benchmarking ; Lagomorpha
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57098-8
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  9. Article: Pectin Nanoparticle-Loaded Soft Coral

    Hassan, Nevine H / El-Hawary, Seham S / Emam, Mahmoud / Rabeh, Mohamed A / Tantawy, Mohamed A / Seif, Mohamed / Abd-Elal, Radwa M A / Bringmann, Gerhard / Abdelmohsen, Usama Ramadan / Selim, Nabil M

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 7

    Abstract: This study shed light for the first time on ... ...

    Abstract This study shed light for the first time on the
    Language English
    Publishing date 2023-07-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16070957
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  10. Article: Neglected bilateral geno valgum deformity managed with a dynamic compression plate and the ilizarov construct: a case report.

    Ibrahim, Yasin B / Mohamed, Abdullahi Y / Ibrahim, Hassan S / Cicek, Engin I / Mohamed, Abdulkhalek H / May, Hasan

    Annals of medicine and surgery (2012)

    2023  Volume 85, Issue 5, Page(s) 1911–1914

    Abstract: Deformities of the lower limb are common in childhood; however, they are mainly variations of the natural growth pattern. The rare case showed up late with a genu valgum deformity centered on both tibias and a closed physis.: Case presentation: A 20- ... ...

    Abstract Deformities of the lower limb are common in childhood; however, they are mainly variations of the natural growth pattern. The rare case showed up late with a genu valgum deformity centered on both tibias and a closed physis.
    Case presentation: A 20-year-old male has suffered from bilateral knee pain and genu valgum deformity centered at both tibias with a closed physis. Management was challenging, requiring multiple surgeries and high patient cooperation. The patient underwent two surgeries: a right-sided osteotomy and Ilizarov fixation with gradual deformity correction. In the second operation, a proximal tibia osteotomy of the left side was executed with acute correction of the deformity and open reduction and internal fixation of the tibia with a medial tibial dynamic compression plate. Ultimately, the authors successfully corrected both leg deformities.
    Conclusion: This results reflect the efficacy of dynamic compression plates and Ilizarov for correcting genu valgum deformity in patients with closed epiphyseal plates.
    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000000405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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