LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 887

Search options

  1. Book: Diversityorientiertes Betriebliches Gesundheitsmanagement

    Faller, Gudrun

    Integration von Gesundheit und Vielfalt in Arbeits- und Organisationskontexten

    2023  

    Author's details Gudrun Faller
    Keywords Antidiskriminierung ; Antidiskriminierung am Arbeitsplatz ; Antidiskriminierung in Unternehmen ; Arbeitsschutz ; Arbeitssicherheit ; Betriebliches Gesundheitsmanagement ; Diversity ; Diversity Management ; Gesundheit ; Gesundheitsförderung ; Gesundheitsmanagement ; Personalmanagement ; Soziale Arbeit ; Vielfalt
    Language German
    Size 252 Seiten, Diagramme, 23 cm x 15 cm
    Edition 1. Auflage
    Publisher Beltz Juventa
    Publishing place Weinheim
    Publishing country Germany
    Document type Book
    HBZ-ID HT030008832
    ISBN 978-3-7799-7531-1 ; 3-7799-7531-9 ; 9783779975328 ; 3779975327
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 A 609 available for loan (reading room) Lesesaal EG

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Precision measurement, scientific personalities and error budgets: the sine quibus non for big G determinations.

    Faller, James E

    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

    2014  Volume 372, Issue 2026

    Abstract: Determinations of the Newtonian constant of gravitation (big G) fit into the oftentimes ... experiments and determinations of the fundamental constants. The determination of big G-a measurement ... cunning of experimental physicists. In spite of the fact that, on the scale of the Universe, big G's ...

    Abstract Determinations of the Newtonian constant of gravitation (big G) fit into the oftentimes-unappreciated area of physics called precision measurement-an area which includes precision measurements, null experiments and determinations of the fundamental constants. The determination of big G-a measurement which on the surface appears deceptively simple-continues to be one of Nature's greatest challenges to the skills and cunning of experimental physicists. In spite of the fact that, on the scale of the Universe, big G's effects are so large as to single-handedly hold everything together, on the scale of an individual research laboratory, big G's effects are so small that they go unnoticed…hidden in a background of much larger forces and noise sources. It is this 'smallness' that makes determining the precise value of this (seemingly unrelated to the rest of physics) fundamental constant so difficult.
    Language English
    Publishing date 2014-10-13
    Publishing country England
    Document type Review
    ZDB-ID 208381-4
    ISSN 1471-2962 ; 1364-503X ; 0080-4614 ; 0264-3820 ; 0264-3952
    ISSN (online) 1471-2962
    ISSN 1364-503X ; 0080-4614 ; 0264-3820 ; 0264-3952
    DOI 10.1098/rsta.2014.0023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 46/25: Show issues
    Z PHI 2: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Telomere-homologous G-rich oligonucleotides sensitize human ovarian cancer cells to TRAIL-induced growth inhibition and apoptosis.

    Sarkar, Sibaji / Faller, Douglas V

    Nucleic acid therapeutics

    2013  Volume 23, Issue 3, Page(s) 167–174

    Abstract: G-rich T-oligos (GT-oligos; oligonucleotides with homology to telomeres) elicit a DNA damage ...

    Abstract G-rich T-oligos (GT-oligos; oligonucleotides with homology to telomeres) elicit a DNA damage response in cells and induce cytotoxic effects in certain tumor cell lines. We have previously shown that GT-oligo inhibits growth, arrests cell cycle, and induces apoptosis in ovarian, pancreatic, and prostate cancer cells. However, not all ovarian cancer cell lines are susceptible to GT-oligo exposure. GT-oligo was found to induce transcript expression of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors DR-4 and DR-5, which are generally silenced in ovarian cancer cells, rendering them insensitive to TRAIL. Exposure of TRAIL- and GT-oligo-resistant cell lines to GT-oligo rendered them sensitive to the cytotoxic effects of TRAIL, producing more than additive inhibition of growth. An intracellular inhibitor of the extrinsic apoptotic pathway, FLICE-like Inhibitory Protein-Short (FLIPs), was down-regulated and Jun kinase (JNK) was activated by exposure to GT-oligo. JNK inhibition partially reversed the growth inhibition caused by the combination of GT-oligo and TRAIL indicating partial involvement of the Jun kinase pathway in the resulting cytotoxic effect. Both capase-8 and caspases 3/7 were activated by exposure to GT-oligo plus TRAIL, consistent with activation of the extrinsic apoptotic pathway. These results demonstrate a novel way of sensitizing resistant ovarian cancer cells to TRAIL-mediated cytotoxicity.
    MeSH term(s) Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; CASP8 and FADD-Like Apoptosis Regulating Protein/metabolism ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 7/genetics ; Caspase 7/metabolism ; Caspase 8/genetics ; Caspase 8/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Synergism ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase 4/metabolism ; Oligonucleotides/genetics ; Oligonucleotides/pharmacology ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Recombinant Proteins/pharmacology ; Signal Transduction/drug effects ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; Telomere/drug effects ; Telomere/genetics
    Chemical Substances Antineoplastic Agents ; CASP8 and FADD-Like Apoptosis Regulating Protein ; Oligonucleotides ; Receptors, TNF-Related Apoptosis-Inducing Ligand ; Recombinant Proteins ; TNF-Related Apoptosis-Inducing Ligand ; TNFRSF10A protein, human ; TNFSF10 protein, human ; MAP Kinase Kinase 4 (EC 2.7.12.2) ; CASP8 protein, human (EC 3.4.22.-) ; Caspase 3 (EC 3.4.22.-) ; Caspase 7 (EC 3.4.22.-) ; Caspase 8 (EC 3.4.22.-)
    Language English
    Publishing date 2013-05-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2639888-6
    ISSN 2159-3345 ; 2159-3337
    ISSN (online) 2159-3345
    ISSN 2159-3337
    DOI 10.1089/nat.2012.0401
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: The Measurement of Little g: A Fertile Ground for Precision Measurement Science.

    Faller, James E

    Journal of research of the National Institute of Standards and Technology

    2005  Volume 110, Issue 6, Page(s) 559–581

    Abstract: ... after 1905. I'll do this by talking about the measurement of little g, the free-fall acceleration ...

    Abstract The occasion of the 100th anniversary of Einstein's "golden year" provides a wonderful opportunity to discuss some aspects of gravity-gravitation being an interest of Einstein's that occurred a few years after 1905. I'll do this by talking about the measurement of little g, the free-fall acceleration on the Earth's surface that is mainly due to the Earth's gravity but whose value is also affected by centrifugal forces that are a result of the Earth's rotation. I will also describe two equivalence experiments and a test of the inverse-square law of gravitation. Finally, I will make some observations on the science of precision measurement-a subject that underpins much of scientific progress.
    Language English
    Publishing date 2005-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1473724-3
    ISSN 1044-677X ; 0160-1741
    ISSN 1044-677X ; 0160-1741
    DOI 10.6028/jres.110.082
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Future Challenges for Work-Related Health Promotion in Europe: A Data-Based Theoretical Reflection.

    Faller, Gudrun

    International journal of environmental research and public health

    2021  Volume 18, Issue 20

    Abstract: This contribution is a theoretical reflection based on statistical and empirical data as well as concepts proposed by other authors or institutions. Based on the thesis that the respective social developments equally influence and limit the orientation ... ...

    Abstract This contribution is a theoretical reflection based on statistical and empirical data as well as concepts proposed by other authors or institutions. Based on the thesis that the respective social developments equally influence and limit the orientation and design of workplace health promotion, this article deals with the challenges that arise from the contemporary social, political and economic developments for a needs-oriented and effective workplace health promotion. On the basis of a historical review of the lines of development in workplace health promotion, beginning with the Ottawa Charter in 1986, the field of tension in which work-related health promotion approaches generally operate is first outlined. Based on the results of a keyword search in relevant European statistics databases and specialized databases on the topics of demographic change, labor migration and digitalization and flexibilization of work, current development trends in the world of work are traced, priority desiderata for a future design of health promotion are derived from these, and their chances of realization are reflected upon. On the basis of the data collected, it becomes clear that today's world of work is characterized by multidimensional diversification processes, which are accompanied by the risk of worsening social inequalities. The conclusion is that future concepts of workplace health promotion must be more universal than previous approaches, which are often limited to the focus of individual behavioral prevention. The attempt to promote workplace health promotion with economic benefit arguments also runs the risk of reinforcing social inequality. The task of effective workplace health promotion, conversely, must be to initiate critical reflection on current priorities.
    MeSH term(s) Europe ; Health Promotion ; Workplace
    Language English
    Publishing date 2021-10-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph182010996
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book ; Thesis: Qualitätsaspekte hochschulbezogener Gesundheitsförderung

    Faller, Gudrun

    Empfehlungen auf Grundlage eines deutsch-anglo-amerikanischen Vergleichs

    (Europäische Hochschulschriften : Reihe 22, Soziologie ; 407)

    2005  

    Author's details Gudrun Faller
    Series title Europäische Hochschulschriften : Reihe 22, Soziologie ; 407
    Europäische Hochschulschriften
    Europäische Hochschulschriften ; Reihe 22, Soziologie
    Collection Europäische Hochschulschriften
    Europäische Hochschulschriften ; Reihe 22, Soziologie
    Keywords Deutschland ; Hochschule ; Gesundheitsförderung
    Subject Health Promotion ; Hochschulwesen ; Hochschulsystem ; Hochschulen
    Language German
    Size 362 S. : graph. Darst.
    Publisher Lang
    Publishing place Frankfurt am Main u.a.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bielefeld, Univ., Diss., 2005
    HBZ-ID HT014538858
    ISBN 3-631-54363-8 ; 978-3-631-54363-4
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 5934 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Umsetzung Betrieblicher Gesundheitsförderung/Betrieblichen Gesundheitsmanagements in Deutschland: Stand und Entwicklungsbedarfe der einschlägigen Forschung.

    Faller, G

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

    2016  Volume 80, Issue 3, Page(s) 278–285

    Abstract: Aim: The data on health management programmes in German companies show quite heterogeneous results. The aim of the study was to gain more transparency into the cause of these discrepancies as well as information on factors influencing the willingness of ...

    Title translation Implementation of Workplace Health Promotion/Workplace Health Management in Germany: State-of-the Art and Need for Further Research.
    Abstract Aim: The data on health management programmes in German companies show quite heterogeneous results. The aim of the study was to gain more transparency into the cause of these discrepancies as well as information on factors influencing the willingness of companies to implement such programmes.
    Methods: Based on a systematic database search, relevant studies were identified and comparative analysis of their contents was carried out.
    Results: The existing studies on the health management programmes in German companies reveal significant discrepancies in terms of their research question, representativeness, approach and design. Nevertheless, they do reveal certain trends identifying significant factors that influence the willingness of companies to implement such programmes.
    Conclusion: In the design of future studies to analyse the distribution of corporate health management programmes, there is a need to agree on common definitions and data collection methods and how the results are to be categorised. When evaluating the effects of corporate programmes, the quantitative data would need to be supplemented with qualitative data that would be capable of identifying how such programmes are implemented and the associated organisation-specific cultural patterns.
    MeSH term(s) Germany ; Health Promotion ; Humans ; Workplace
    Language German
    Publishing date 2016-03-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0042-100624
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.402: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Characterization of fluid distribution through a porous substrate under dynamic g conditions.

    Shah, S / Faller, W E / Hoehn, A / Birdsong, M / Luttges, M W

    Biomedical sciences instrumentation

    1993  Volume 29, Page(s) 401–408

    Abstract: ... distributions under g-level conditions. Even though the duration of the experiment was short, gravity induced ...

    Abstract Dedicated electronic hardware has been constructed to monitor fluid distributions inside a plant rooting/nutrient substrate (Rockwool). With this hardware the effect of dynamically varying gravity states, from enhanced 2g to reduced 0.01g, on solution distributions inside a cube of substrate was monitored aboard the NASA KC-135 reduced gravity research aircraft. The 8 vertices and the center of the cube were used to place sinusoidal voltage sources (electrodes), emitting different fixed frequencies, inside the substrate. Using another set of 9 electrodes the voltage fields were detected across all frequencies. Since the substrate cannot conduct, those frequencies which appeared on any detector (sensor) were indicative of the conductive liquid pathways inside the substrate. An analysis algorithm was developed to visualize the fluid distributions under g-level conditions. Even though the duration of the experiment was short, gravity induced changes in fluid position were readily and reliably detected. Since fluids carry the nutrients necessary for plant growth these data and techniques can lead to the development of a uniform nutrient supply system supportive of optimal plant growth in space.
    MeSH term(s) Algorithms ; Data Interpretation, Statistical ; Extraterrestrial Environment ; Models, Biological ; Plant Physiological Phenomena ; Rheology
    Language English
    Publishing date 1993
    Publishing country United States
    Document type Journal Article
    ISSN 0067-8856 ; 0077-3565 ; 1054-0032
    ISSN 0067-8856 ; 0077-3565 ; 1054-0032
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Coarse-grained modeling of polystyrene-modified CNTs and their interactions with lipid bilayers.

    Gul, Gulsah / Faller, Roland / Ileri-Ercan, Nazar

    Biophysical journal

    2023  Volume 122, Issue 10, Page(s) 1748–1761

    Abstract: In the present work, we describe Martini3 coarse-grained models of polystyrene and carboxyl-terminated polystyrene functionalized carbon nanotubes (CNTs) and investigate their interactions with lipid bilayers with and without cholesterol (CHOL) using ... ...

    Abstract In the present work, we describe Martini3 coarse-grained models of polystyrene and carboxyl-terminated polystyrene functionalized carbon nanotubes (CNTs) and investigate their interactions with lipid bilayers with and without cholesterol (CHOL) using molecular dynamics simulations. By changing the polystyrene chain length and grafting density at the end ring of the CNTs at two different nanotube concentrations, we observe the translocation of nanoparticles as well as changes in the lipid bilayer properties. Our results show that all developed models passively diffuse into the membranes without causing any damage to the membrane integrity, although high concentrations of CNTs induce structural and elastic changes in lipid bilayers. In the presence of CHOL, increasing CNT concentration results in decreased rates of CHOL transmembrane motions. On the other hand, CNTs are prone to lipid and polystyrene blockage, which affects their equilibrated configurations, and tilting behavior within the membranes. Hence, we demonstrate that polystyrene-functionalized CNTs are promising drug-carrier agents. However, polystyrene chain length and grafting density are important factors to consider to enhance the efficiency of drug delivery.
    MeSH term(s) Lipid Bilayers/chemistry ; Nanotubes, Carbon ; Polystyrenes ; Molecular Dynamics Simulation ; Cholesterol/chemistry
    Chemical Substances Lipid Bilayers ; Nanotubes, Carbon ; Polystyrenes ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218078-9
    ISSN 1542-0086 ; 0006-3495
    ISSN (online) 1542-0086
    ISSN 0006-3495
    DOI 10.1016/j.bpj.2023.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 235: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 2: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Shunt intra-auriculaire D-G en l'absence d'augmentation des pressions dans les cavitiés cardiaques droites.

    Chaouat, A / Faller, M / Kessler, R / Petit, H / Schlossmacher, P / Schott, R / Bugnet, A S / Djellid, D / Weitzenblum, E

    Revue des maladies respiratoires

    1999  Volume 16 Suppl 3, Page(s) S205

    Title translation Right-left intra-atrial shunt in the absence of elevated pressures in the right cardiac cavities.
    MeSH term(s) Aged ; Cardiac Catheterization ; Dyspnea/etiology ; Echocardiography, Transesophageal ; Heart Aneurysm/complications ; Heart Aneurysm/diagnosis ; Heart Aneurysm/physiopathology ; Heart Atria ; Heart Septal Defects, Atrial/complications ; Heart Septal Defects, Atrial/diagnosis ; Heart Septal Defects, Atrial/physiopathology ; Humans ; Ventricular Pressure
    Language French
    Publishing date 1999-01
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 605743-3
    ISSN 0761-8425 ; 0301-0279
    ISSN 0761-8425 ; 0301-0279
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1945: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 94: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top