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  1. Book: Multiple sclerosis

    Rodriguez, Moses / Kantarci, Orhun H. / Pirko, Istvan

    (Contemporary neurology series ; 84)

    2013  

    Author's details Moses Rodriguez ; Orhun H. Kantarci ; Istvan Pirko
    Series title Contemporary neurology series ; 84
    Collection
    Keywords Multiple Sclerosis
    Language English
    Size XIII, 199 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017726591
    ISBN 978-0-19-974046-8 ; 978-0-19-997019-3 ; 0-19-974046-1 ; 0-19-997019-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 2011 available for loan (reading room) Lesesaal EG

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  2. Article: Neuroradiological evaluation of demyelinating disease.

    Tillema, Jan-Mendelt / Pirko, Istvan

    Therapeutic advances in neurological disorders

    2013  Volume 6, Issue 4, Page(s) 249–268

    Abstract: Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging ... ...

    Abstract Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging criteria. The advances of both neuroimaging techniques and important discoveries in immunology have produced an improved understanding of these conditions and classification. Neuroimaging plays a central role in the accurate diagnosis, prognosis, disease monitoring and research efforts that are being undertaken in this disease. This review focuses on the imaging spectrum of acquired demyelinating disease.
    Language English
    Publishing date 2013-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2442245-9
    ISSN 1756-2864 ; 1756-2856
    ISSN (online) 1756-2864
    ISSN 1756-2856
    DOI 10.1177/1756285613478870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Evaluating the new soil erosion map of Hungary—A semiquantitative approach

    Waltner, István / Béla Pirkó / Csaba Centeri / Katalin Takács / László Pásztor / Péter László / Sándor Koós

    Land degradation & development. 2018 Apr., v. 29, no. 4

    2018  

    Abstract: Soil erosion by water is one of the most significant forms of soil degradation globally, especially in Europe. A new soil erosion risk map of Hungary has been compiled and published recently, using the combined outputs of the Universal Soil Loss Equation ...

    Abstract Soil erosion by water is one of the most significant forms of soil degradation globally, especially in Europe. A new soil erosion risk map of Hungary has been compiled and published recently, using the combined outputs of the Universal Soil Loss Equation and Pan‐European Soil Erosion Risk Assessment models. Our study aimed at providing evaluation of the map by using semiquantitative validation data obtained from the Hungarian Soil Degradation Subsystem of the National Environmental Information System. The Soil Degradation Subsystem database contained information at farm level as well as indicators based on laboratory data for 5‐ha representative plots. On the basis of the semiquantitative analysis, the map results align well with the farm‐based degradation data and provide viable information not only at the regional scale but also at the farm scale. However, indicators from representative plots did not support model results, indicating possible conflict between farm‐ and plot‐level data. Cross‐comparison of these indicators showed only limited correlation between farm‐ and plot‐level indicators.
    Keywords databases ; farms ; information systems ; risk ; risk assessment ; soil erosion ; Universal Soil Loss Equation ; Hungary
    Language English
    Dates of publication 2018-04
    Size p. 1295-1302.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 1319202-4
    ISSN 1085-3278
    ISSN 1085-3278
    DOI 10.1002/ldr.2916
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5058: Show issues

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  4. Article ; Online: MS cortical lesion or not? Double inversion recovery MRI reveals some answers and uncertainties.

    Chen, Jacqueline T / Pirko, Istvan

    Neurology

    2011  Volume 76, Issue 5, Page(s) 412–413

    MeSH term(s) Cerebral Cortex/pathology ; Diagnosis, Differential ; Disease Progression ; Humans ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/standards ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/pathology ; Nerve Fibers, Myelinated/pathology ; Practice Guidelines as Topic/standards ; Predictive Value of Tests ; Sensitivity and Specificity
    Language English
    Publishing date 2011-02-01
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0b013e31820a0d6e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.153: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 18: Show issues
    Zs.MO 374: Show issues

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  5. Article ; Online: Advances in understanding gray matter pathology in multiple sclerosis: are we ready to redefine disease pathogenesis?

    Zivadinov, Robert / Pirko, Istvan

    BMC neurology

    2012  Volume 12, Page(s) 9

    Abstract: The purpose of this special issue in BMC Neurology is to summarize advances in our understanding of the pathological, immunological, imaging and clinical concepts of gray matter (GM) pathology in patients with multiple sclerosis (MS). Review articles by ... ...

    Abstract The purpose of this special issue in BMC Neurology is to summarize advances in our understanding of the pathological, immunological, imaging and clinical concepts of gray matter (GM) pathology in patients with multiple sclerosis (MS). Review articles by Lucchinetti and Popescu, Walker and colleagues, Hulst and colleagues and Horakova and colleagues summarize important recent advances in understanding GM damage and its implications to MS pathogenesis. They also raise a number of important new questions and outline comprehensive approaches to addressing those questions in years to come. In the last decade, the use of immunohistochemistry staining methods and more advanced imaging techniques to detect GM lesions, like double inversion recovery, contributed to a surge of studies related to cortical and subcortical GM pathology in MS. It is becoming more apparent from recent biopsy studies that subpial cortical lesions in early MS are highly inflammatory. The mechanisms responsible for triggering meningeal inflammation in MS patients are not yet elucidated, and they should be further investigated in relation to their role in initiating and perpetuating the disease process. Determining the role of antigens, environmental and genetic factors in the pathogenesis of GM involvement in MS is critical. The early involvement of cortical and subcortical GM damage in MS is very intriguing and needs to be further studied. As established in numerous cross-sectional and longitudinal studies, GM damage is a better predictor of physical disability and cognitive impairment than WM damage. Monitoring the evolution of GM damage is becoming an important marker in predicting future disease course and response to therapy in MS patients.
    MeSH term(s) Brain/immunology ; Brain/pathology ; Humans ; Multiple Sclerosis/immunology ; Multiple Sclerosis/pathology
    Language English
    Publishing date 2012-03-06
    Publishing country England
    Document type Editorial ; Introductory Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1471-2377
    ISSN (online) 1471-2377
    DOI 10.1186/1471-2377-12-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Transcranial sonography of deep gray nuclei: a new outcome measure in multiple sclerosis?

    Pirko, Istvan / Zivadinov, Robert

    Neurology

    2009  Volume 73, Issue 13, Page(s) 1006–1007

    MeSH term(s) Cerebrovascular Circulation ; Humans ; Multiple Sclerosis/diagnostic imaging ; Prosencephalon/blood supply ; Ultrasonography, Doppler, Transcranial
    Language English
    Publishing date 2009-09-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0b013e3181bb1de9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.153: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 18: Show issues
    Zs.MO 374: Show issues

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  7. Article ; Online: Novel Agents and Emerging Treatment Strategies in Multiple Sclerosis. What Role for Cladribine?

    Francesca Bagnato / Istvan Pirko

    Clinical Medicine Insights: Therapeutics, Vol 2011, Iss 3, Pp 425-

    2011  Volume 439

    Keywords Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R ; DOAJ:Therapeutics ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2011-10-01T00:00:00Z
    Publisher Libertas Academica
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Book: Magnetic resonance imaging of the central nervous system in experimental animals

    Pirko, Istvan

    2006  

    Abstract: ... including multiple sclerosis, as reported in the following recent articles: McDole J., Johnson A.J., Pirko ... 28:256-61. Pirko I., Fricke S.T., Johnson A.J., Rodriguez M., Macura S.I. Magnetic resonance imaging ... Pirko I., Gamez J., Johnson A.J., Macura S.I., Rodriguez M. Dynamics of MRI lesion development ...

    Title variant Magnetic resonance imaging of the TMEV model of multiple sclerosis
    Author's details Istvan Pirko
    Abstract (CIT): Dr. Pirko's work has focused on inflammatory conditions of the central nervous system, including multiple sclerosis, as reported in the following recent articles: McDole J., Johnson A.J., Pirko I. The role of CD8+ T-cells in lesion formation and axonal dysfunction in multiple sclerosis. Neurol Res. 2006; 28:256-61. Pirko I., Fricke S.T., Johnson A.J., Rodriguez M., Macura S.I. Magnetic resonance imaging, microscopy, and spectroscopy of the central nervous system in experimental animals, NeuroRx 2005; 2:250-64. Pirko I., Gamez J., Johnson A.J., Macura S.I., Rodriguez M. Dynamics of MRI lesion development in an animal model of viral-induced acute progressive CNS demyelination. Neuroimage. 2004; 21:576-82.
    MeSH term(s) Multiple Sclerosis/diagnosis ; Animal Models ; Magnetic Resonance Imaging
    Language English
    Publisher National Institutes of Health
    Publishing place Bethesda, Md
    Document type Book
    Note Open-captioned. ; Title from screen banner (viewed Dec. 19, 2006). ; Streaming video (55 min. : sd., col.). ; Copyright: This is a work of the United States Government.
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: Sensitivity vs specificity: progress and pitfalls in defining MRI criteria for pediatric MS.

    Chitnis, Tanuja / Pirko, Istvan

    Neurology

    2009  Volume 72, Issue 11, Page(s) 952–953

    MeSH term(s) Child ; Encephalomyelitis, Acute Disseminated/complications ; Encephalomyelitis, Acute Disseminated/pathology ; Humans ; Lupus Vasculitis, Central Nervous System/complications ; Lupus Vasculitis, Central Nervous System/pathology ; Magnetic Resonance Imaging/standards ; Migraine Disorders/complications ; Migraine Disorders/pathology ; Multiple Sclerosis/pathology
    Language English
    Publishing date 2009-03-17
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/01.wnl.0000344414.57976.97
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.153: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 18: Show issues
    Zs.MO 374: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Advances in understanding gray matter pathology in multiple sclerosis

    Zivadinov Robert / Pirko Istvan

    BMC Neurology, Vol 12, Iss 1, p

    Are we ready to redefine disease pathogenesis?

    2012  Volume 9

    Abstract: Abstract The purpose of this special issue in BMC Neurology is to summarize advances in our understanding of the pathological, immunological, imaging and clinical concepts of gray matter (GM) pathology in patients with multiple sclerosis (MS). Review ... ...

    Abstract Abstract The purpose of this special issue in BMC Neurology is to summarize advances in our understanding of the pathological, immunological, imaging and clinical concepts of gray matter (GM) pathology in patients with multiple sclerosis (MS). Review articles by Lucchinetti and Popescu, Walker and colleagues, Hulst and colleagues and Horakova and colleagues summarize important recent advances in understanding GM damage and its implications to MS pathogenesis. They also raise a number of important new questions and outline comprehensive approaches to addressing those questions in years to come. In the last decade, the use of immunohistochemistry staining methods and more advanced imaging techniques to detect GM lesions, like double inversion recovery, contributed to a surge of studies related to cortical and subcortical GM pathology in MS. It is becoming more apparent from recent biopsy studies that subpial cortical lesions in early MS are highly inflammatory. The mechanisms responsible for triggering meningeal inflammation in MS patients are not yet elucidated, and they should be further investigated in relation to their role in initiating and perpetuating the disease process. Determining the role of antigens, environmental and genetic factors in the pathogenesis of GM involvement in MS is critical. The early involvement of cortical and subcortical GM damage in MS is very intriguing and needs to be further studied. As established in numerous cross-sectional and longitudinal studies, GM damage is a better predictor of physical disability and cognitive impairment than WM damage. Monitoring the evolution of GM damage is becoming an important marker in predicting future disease course and response to therapy in MS patients.
    Keywords Multiple sclerosis ; Gray matter ; Pathology ; Meningeal inflammation ; Cortical ; Subcortical ; MRI ; Double inversion recovery ; Atrophy ; Clinical ; Treatment ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610
    Language English
    Publishing date 2012-03-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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