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  1. Book: Plastic Surgery

    Chang, James / Neligan, Peter C

    Volume 6: Hand and Upper Limb

    2023  

    Language English
    Size 1096 p.
    Edition 5
    Publisher Elsevier Science
    Document type Book
    Note PDA Manuell_24
    ISBN 9780323810432 ; 0323810438
    Database PDA

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  2. Article: Spontaneous Adductor Hematoma in a 75-Year-Old Male With Acute Thigh Bruises.

    Kim, James / Rhim, Hye Chang / Schneider, Jeffrey C

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54079

    Abstract: Patients with a history of blood clots are commonly placed on anticoagulation therapy, but a common adverse effect of this therapy is hemorrhage. Our patient with a history of left ventricle thrombus in a free-standing inpatient rehabilitation hospital ... ...

    Abstract Patients with a history of blood clots are commonly placed on anticoagulation therapy, but a common adverse effect of this therapy is hemorrhage. Our patient with a history of left ventricle thrombus in a free-standing inpatient rehabilitation hospital had ecchymoses that expanded over a large portion of the posterior thigh in one day. The rapid expansion of the ecchymoses coupled with a decline in hemoglobin levels prompted an immediate evaluation that showed an intramuscular hematoma. With hemoglobin levels dropping significantly, the patient was then transferred to the emergency department for higher levels of care. A multidisciplinary team of vascular surgery and electrophysiology physicians decided to discontinue anticoagulation and monitor the hematoma with serial compartment checks. The hematoma had stabilized throughout the hospital stay without surgical intervention. This case will discuss the difficulty of managing a patient with a history of previous blood clots with an adductor magnus hematoma in the setting of concurrent iatrogenic anticoagulation. Furthermore, we will review the current management and evaluation of intramuscular hematomas.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54079
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  3. Article ; Online: Enantioselective and Regiodivergent Synthesis of Propargyl- and Allenylsilanes through Catalytic Propargylic C-H Deprotonation.

    Zhu, Jin / Xiang, Hengye / Chang, Hai / Corcoran, James C / Ding, Ruiqi / Xia, Yue / Liu, Peng / Wang, Yi-Ming

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 16, Page(s) e202318040

    Abstract: We report a highly enantioselective intermolecular C-H bond silylation catalyzed ... by a phosphoramidite-ligated iridium catalyst. Under reagent-controlled protocols, propargylsilanes resulting from C(sp ...

    Abstract We report a highly enantioselective intermolecular C-H bond silylation catalyzed by a phosphoramidite-ligated iridium catalyst. Under reagent-controlled protocols, propargylsilanes resulting from C(sp
    Language English
    Publishing date 2024-03-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202318040
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  4. Article ; Online: Primary cutaneous mucormycosis of the lower extremity in a male patient with diabetes.

    Chang, Nicholas / McKee, James / Marmolejo, Valerie / Cua, Arnold Paul C

    Wounds : a compendium of clinical research and practice

    2023  Volume 35, Issue 3, Page(s) E98–E101

    Abstract: Introduction: Mucormycosis is a rare but serious angioinvasive fungal infection that can affect the cutaneous system. Primary cutaneous mucormycosis is caused by direct inoculation and is most prevalent in immunocompromised hosts, particularly those ... ...

    Abstract Introduction: Mucormycosis is a rare but serious angioinvasive fungal infection that can affect the cutaneous system. Primary cutaneous mucormycosis is caused by direct inoculation and is most prevalent in immunocompromised hosts, particularly those with diabetes. A high index of suspicion is necessary for this condition in patients with rapid and deep extension of necrosis despite aggressive surgical intervention. Deep tissue specimens should be sent for fungal culture and histologic analysis for confirmation of the diagnosis. Early and aggressive debridement to prevent spread to deeper tissues and organs, concurrent antifungal therapy, and medical management of comorbidities are paramount to the treatment of primary cutaneous mucormycosis.
    Case report: This case report highlights the presentation and recommended treatment of primary cutaneous mucormycosis in 1 patient for reduced morbidity and mortality associated with this type of infection.
    MeSH term(s) Humans ; Male ; Mucormycosis/complications ; Mucormycosis/diagnosis ; Mucormycosis/therapy ; Diabetes Mellitus ; Skin/pathology ; Necrosis ; Lower Extremity/pathology ; Debridement/adverse effects
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1214936-6
    ISSN 1943-2704 ; 1044-7946
    ISSN (online) 1943-2704
    ISSN 1044-7946
    DOI 10.25270/wnds/22045
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    Zs.A 4153: Show issues Location:
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  5. Article ; Online: Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline: 2024 Amendment.

    Holzbeierlein, Jeffrey M / Bixler, Brooke R / Buckley, David I / Chang, Sam S / Holmes, Rebecca / James, Andrew C / Kirkby, Erin / McKiernan, James M / Schuckman, Anne K

    The Journal of urology

    2024  Volume 211, Issue 4, Page(s) 533–538

    Abstract: ... B (moderate), or C (low) in support of Strong, Moderate, or Conditional Recommendations ...

    Abstract Purpose: The purpose of this American Urological Association (AUA)/Society of Urologic Oncology (SUO) guideline amendment is to provide a useful reference on the effective evidence-based treatment strategies for non-muscle invasive bladder cancer (NMIBC).
    Materials and methods: In 2023, the NMIBC guideline was updated through the AUA amendment process in which newly published literature is reviewed and integrated into previously published guidelines in an effort to maintain currency. The amendment allowed for the incorporation of additional literature released since the previous 2020 amendment. The updated search gathered literature from July 2019 to May 2023. This review identified 1918 abstracts, of which 75 met inclusion criteria.When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) in support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions.
    Results: Updates were made to statements on variant histologies, urine markers after diagnosis of bladder cancer, intravesical therapy, BCG maintenance, enhanced cystoscopy, and future directions. Further revisions were made to the methodology and reference sections as appropriate.
    Conclusions: This guideline seeks to improve clinicians' ability to evaluate and treat patients with NMIBC based on currently available evidence. Future studies will be essential to further support or refine these statements to improve patient care.
    MeSH term(s) Humans ; Non-Muscle Invasive Bladder Neoplasms ; Urinary Bladder Neoplasms/diagnosis ; Urinary Bladder Neoplasms/therapy ; Urology ; Cystoscopy ; Treatment Outcome
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003846
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  6. Article ; Online: Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/SUO GUIDELINE (2017; Amended 2020, 2024).

    Holzbeierlein, Jeffrey / Bixler, Brooke R / Buckley, David I / Chang, Sam S / Holmes, Rebecca S / James, Andrew C / Kirkby, Erin / McKiernan, James M / Schuckman, Anne

    The Journal of urology

    2024  , Page(s) 101097JU0000000000003981

    Abstract: ... of evidence was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong ...

    Abstract Purpose: Although representing approximately 25% of patients diagnosed with bladder cancer, muscle-invasive bladder cancer (MIBC) carries a significant risk of death that has not significantly changed in decades. Increasingly, clinicians and patients recognize the importance of multidisciplinary collaborative efforts that take into account survival and quality of life concerns. This guideline provides a risk-stratified, clinical framework for the management of muscle-invasive urothelial bladder cancer.
    Methodology/methods: In 2024, the MIBC guideline was updated through the AUA amendment process in which newly published literature is reviewed and integrated into previously published guidelines in an effort to maintain currency. The amendment allowed for the incorporation of additional literature released since the previous 2020 amendment. The updated search gathered literature from May 2020 to November 2023. This review identified 3739 abstracts, of which 46 met inclusion criteria.When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions.
    Results: Updates were made regarding neoadjuvant/adjuvant chemotherapy, radical cystectomy, pelvic lymphadenectomy, multi-modal bladder preserving therapy, and future directions. Further revisions were made to the methodology and reference sections as appropriate.
    Conclusions: This guideline seeks to improve clinicians' ability to evaluate and treat patients with MIBC based on currently available evidence. Future studies will be essential to further support or refine these statements to improve patient care.
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003981
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  7. Article ; Online: Association between the diagnostic classification of newly diagnosed coronary artery disease and future heart failure development.

    Williams, Brent A / Voyce, Stephen / Blankenship, James C / Chang, Alexander R

    Coronary artery disease

    2023  Volume 34, Issue 5, Page(s) 341–350

    Abstract: Objective: The first clinical manifestation of coronary artery disease (CAD) varies widely from unheralded myocardial infarction (MI) to mild, incidentally detected disease. The primary objective of this study was to quantify the association between ... ...

    Abstract Objective: The first clinical manifestation of coronary artery disease (CAD) varies widely from unheralded myocardial infarction (MI) to mild, incidentally detected disease. The primary objective of this study was to quantify the association between different initial CAD diagnostic classifications and future heart failure.
    Methods: This retrospective study incorporated the electronic health record of a single integrated health care system. Newly diagnosed CAD was classified into a mutually exclusive hierarchy as MI, CAD with coronary artery bypass graft (CABG), CAD with percutaneous coronary intervention, CAD only, unstable angina, and stable angina. An acute CAD presentation was defined when the diagnosis was associated with a hospital admission. New heart failure was identified after the CAD diagnosis.
    Results: Among 28 693 newly diagnosed CAD patients, initial presentation was acute in 47% and manifested as MI in 26%. Within 30 days of CAD diagnosis, MI [hazard ratio (HR) = 5.1; 95% confidence interval: 4.1-6.5] and unstable angina (3.2; 2.4-4.4) classifications were associated with the highest heart failure risk (compared to stable angina), as was acute presentation (2.9; 2.7-3.2). Among stable, heart failure-free CAD patients followed on average 7.4 years, initial MI (adjusted HR = 1.6; 1.4-1.7) and CAD with CABG (1.5; 1.2-1.8) were associated with higher long-term heart failure risk, but an initial acute presentation was not (1.0; 0.9-1.0).
    Conclusion: Nearly 50% of initial CAD diagnoses are associated with hospitalization, and these patients are at high risk of early heart failure. Among stable CAD patients, MI remained the diagnostic classification associated with the highest long-term heart failure risk, however, having an initial acute CAD presentation was not associated with long-term heart failure.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Angina, Stable ; Retrospective Studies ; Risk Factors ; Myocardial Infarction/complications ; Heart Failure ; Myocardial Ischemia/complications ; Angina, Unstable/diagnosis ; Angina, Unstable/etiology
    Language English
    Publishing date 2023-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1047268-x
    ISSN 1473-5830 ; 0954-6928
    ISSN (online) 1473-5830
    ISSN 0954-6928
    DOI 10.1097/MCA.0000000000001243
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  8. Article ; Online: Demystifying theoretical concerns involving respirators with exhalation valves during COVID-19 pandemic.

    Chang, James C / Johnson, James S / Olmsted, Russell N

    American journal of infection control

    2020  Volume 48, Issue 12, Page(s) 1564–1565

    MeSH term(s) COVID-19/prevention & control ; COVID-19/virology ; Equipment Design/psychology ; Exhalation ; Humans ; Respiratory Protective Devices/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2020.08.031
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  9. Article ; Online: Radiotherapy plus immune checkpoint blockade in PD(L)-1-resistant metastatic NSCLC.

    Chang, Joe Y / Verma, Vivek / Welsh, James W / Formenti, Silvia C

    The Lancet. Oncology

    2022  Volume 23, Issue 4, Page(s) e156

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Humans ; Immune Checkpoint Inhibitors ; Lung Neoplasms/drug therapy ; Lung Neoplasms/radiotherapy ; Radiation Oncology
    Chemical Substances Immune Checkpoint Inhibitors
    Language English
    Publishing date 2022-04-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(22)00134-6
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    Zs.MO 460: Show issues

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  10. Article ; Online: Synthesis and Bioluminescence of 'V'-Shaped Firefly Luciferin Analogues Based on A Novel Benzobisthiazole Core.

    Chang, Chia-Hao / Fontaine, Danielle M / Gómez, Sandra / Branchini, Bruce R / Anderson, James C

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2023  Volume 29, Issue 69, Page(s) e202302204

    Abstract: The design of π-extended conjugation 'V'-shaped red shifted bioluminescent D-luciferin analogues based on a novel benzobisthiazole core is described. The divergent synthetic route allowed access to a range of amine donor substituents through an ... ...

    Abstract The design of π-extended conjugation 'V'-shaped red shifted bioluminescent D-luciferin analogues based on a novel benzobisthiazole core is described. The divergent synthetic route allowed access to a range of amine donor substituents through an S
    MeSH term(s) Firefly Luciferin/chemistry ; Luciferases/chemistry ; Light ; Spectrum Analysis ; Luminescent Measurements/methods ; Luciferases, Firefly
    Chemical Substances Firefly Luciferin (5TBB02N29K) ; Luciferases (EC 1.13.12.-) ; Luciferases, Firefly (EC 1.13.12.7)
    Language English
    Publishing date 2023-10-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202302204
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