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  1. Article ; Online: Bifurcation-Lesion PCI Guided by OCT or Angiography.

    Steinacher, Eva / Koller, Lorenz / Niessner, Alexander

    The New England journal of medicine

    2024  Volume 390, Issue 2, Page(s) 187–188

    MeSH term(s) Humans ; Percutaneous Coronary Intervention
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2313258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: PCSK9 inhibition in patients with heart failure: neutral or harmful intervention?

    Niessner, Alexander / Drexel, Heinz

    European heart journal

    2022  Volume 43, Issue 16, Page(s) 1566–1568

    MeSH term(s) Heart Failure/drug therapy ; Humans ; Proprotein Convertase 9 ; Risk Factors
    Chemical Substances PCSK9 protein, human (EC 3.4.21.-) ; Proprotein Convertase 9 (EC 3.4.21.-)
    Language English
    Publishing date 2022-03-07
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Development of Cross-Sector Health Care Quality Indicators Based on Claims Data.

    Gall, Walter / Šinkovec, Hana / Niessner, Alexander / Sulzgruber, Patrick / Heinze, Georg

    Studies in health technology and informatics

    2024  Volume 310, Page(s) 1404–1405

    Abstract: Quality indicators serve as a tool to measure and improve evidence-based health care. Often the transition from inpatient to outpatient care is not sufficiently included. The focus of this work was to develop and to evaluate methods to define relevant ... ...

    Abstract Quality indicators serve as a tool to measure and improve evidence-based health care. Often the transition from inpatient to outpatient care is not sufficiently included. The focus of this work was to develop and to evaluate methods to define relevant cross-sector quality indicators based on Austrian claims data, using myocardial infarction as tracer.
    MeSH term(s) Humans ; Quality Indicators, Health Care ; Ambulatory Care ; Inpatients ; Myocardial Infarction/therapy
    Language English
    Publishing date 2024-01-25
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI231216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Vericiguat: a fifth cornerstone in the treatment of heart failure with reduced ejection fraction?

    Hammer, Andreas / Niessner, Alexander / Sulzgruber, Patrick

    ESC heart failure

    2023  Volume 10, Issue 6, Page(s) 3735–3738

    MeSH term(s) Humans ; Stroke Volume ; Heart Failure/drug therapy ; Treatment Outcome ; Heterocyclic Compounds, 2-Ring
    Chemical Substances vericiguat (LV66ADM269) ; Heterocyclic Compounds, 2-Ring
    Language English
    Publishing date 2023-10-08
    Publishing country England
    Document type Letter
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Statin Intolerance, Bempedoic Acid, and Cardiovascular Outcomes.

    Steinacher, Eva / Sulzgruber, Patrick / Niessner, Alexander

    The New England journal of medicine

    2023  Volume 388, Issue 26, Page(s) 2488

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Dicarboxylic Acids ; Fatty Acids
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid (1EJ6Z6Q368) ; Dicarboxylic Acids ; Fatty Acids
    Language English
    Publishing date 2023-06-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2305917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Surgical or Percutaneous Coronary Revascularization for Heart Failure: a Focus on Symptoms and Stenosis.

    Sulzgruber, Patrick / Baumer, Ulrike / Niessner, Alexander

    Cardiovascular drugs and therapy

    2023  Volume 37, Issue 4, Page(s) 623–624

    MeSH term(s) Humans ; Constriction, Pathologic ; Coronary Artery Bypass ; Percutaneous Coronary Intervention/adverse effects ; Heart Failure/diagnosis ; Heart Failure/surgery ; Treatment Outcome ; Coronary Artery Disease/surgery
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Letter
    ZDB-ID 639068-7
    ISSN 1573-7241 ; 0920-3206
    ISSN (online) 1573-7241
    ISSN 0920-3206
    DOI 10.1007/s10557-023-07439-y
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  7. Article ; Online: Early Initiation of SGLT2 Inhibitors in Acute Heart Failure: a Focus on Diuresis and Renal Protection.

    Hammer, Andreas / Niessner, Alexander / Sulzgruber, Patrick

    Cardiovascular drugs and therapy

    2023  

    Abstract: Purpose: Acute heart failure (AHF) represents a critical and life-threatening condition characterized by the sudden onset or exacerbation of symptoms, such as dyspnea and fluid retention, due to impaired cardiac function. Despite advances in the ... ...

    Abstract Purpose: Acute heart failure (AHF) represents a critical and life-threatening condition characterized by the sudden onset or exacerbation of symptoms, such as dyspnea and fluid retention, due to impaired cardiac function. Despite advances in the treatment of chronic heart failure (HF), the management of AHF remains challenging, with limited therapeutic options available. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have emerged as a promising drug class in AHF management.
    Methods/results: The objective of this article was to conduct a comprehensive review of the existing literature in the domain of SGLT2 inhibitors and their relevance in the context of AHF.
    Conclusion: The existing evidence underscores the importance of SGLT2 inhibitors in enhancing decongestive therapy for AHF patients. Early initiation appears both practical and beneficial, leading to improved and sustained decongestion, a reduction in heart failure-related events, enhanced quality of life, and decreased mortality rates, all while maintaining a favorable safety profile. Consequently, it should be considered to initiate SGLT2 inhibitor treatment as early and as safely as possible to facilitate effective decongestion. However, careful patient selection and monitoring are essential when considering the use of these drugs in the management of AHF.
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639068-7
    ISSN 1573-7241 ; 0920-3206
    ISSN (online) 1573-7241
    ISSN 0920-3206
    DOI 10.1007/s10557-023-07512-6
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  8. Article ; Online: Rivaroxaban in Valvular Atrial Fibrillation - a Critical Appraisal of the INVICTUS Trial.

    Hammer, Andreas / Niessner, Alexander / Sulzgruber, Patrick

    Cardiovascular drugs and therapy

    2023  

    Abstract: Purpose: The efficacy of factor Xa inhibitors in patients with atrial fibrillation (AF) and rheumatic heart disease (RHD) is unknown.: Methods/results: The objective of this article was to conduct a comprehensive evaluation of the INVICTUS trial, an ... ...

    Abstract Purpose: The efficacy of factor Xa inhibitors in patients with atrial fibrillation (AF) and rheumatic heart disease (RHD) is unknown.
    Methods/results: The objective of this article was to conduct a comprehensive evaluation of the INVICTUS trial, an open-label randomized controlled study that compared vitamin K antagonists (VKA) to rivaroxaban in patients with AF and RHD while also considering the existing evidence from literature in this particular area of research.
    Conclusion: The findings of the INVICTUS trial indicated that rivaroxaban was found to be inferior in efficacy to VKA. However, it is important to note that the primary outcome of the trial was driven by sudden death and death caused by mechanical pump failure. As a result, it is necessary to approach the data from this study with caution, and it would be inappropriate to draw parallel conclusions for other causes of valvular AF. Particularly, the perplexing issue of how rivaroxaban could have contributed to both pump failure and sudden cardiac death requires further explanation. Additional data regarding changes in heart failure medication and ventricular function would be essential for proper interpretation.
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639068-7
    ISSN 1573-7241 ; 0920-3206
    ISSN (online) 1573-7241
    ISSN 0920-3206
    DOI 10.1007/s10557-023-07470-z
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  9. Article ; Online: The European Society of Cardiology working group on cardiovascular pharmacotherapy.

    Kaski, Juan Carlos / Niessner, Alexander / Dobrev, Dobromir / Rocca, Bianca

    European heart journal

    2023  Volume 44, Issue 42, Page(s) 4400–4402

    Language English
    Publishing date 2023-10-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad651
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  10. Article ; Online: Rivaroxaban in Rheumatic Heart Disease-Associated Atrial Fibrillation.

    Hammer, Andreas / Niessner, Alexander / Sulzgruber, Patrick

    The New England journal of medicine

    2022  Volume 387, Issue 22, Page(s) 2100

    MeSH term(s) Humans ; Rivaroxaban/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Rheumatic Heart Disease/complications ; Rheumatic Heart Disease/drug therapy
    Chemical Substances Rivaroxaban (9NDF7JZ4M3)
    Language English
    Publishing date 2022-11-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2213437
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