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  1. Article: [DENDRITIC CELL SUBSETS AND FUNCTION].

    Sato, Katsuaki

    Arerugi = [Allergy

    2016  Volume 65, Issue 1, Page(s) 11–6; quiz 16–7

    MeSH term(s) Animals ; Cell Differentiation ; Cytokines/immunology ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Humans ; Immune Tolerance
    Chemical Substances Cytokines
    Language Japanese
    Publishing date 2016-02
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    DOI 10.15036/arerugi.65.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: [ROLE OF DENDRITIC CELLS IN PROTECTIVE SUBLINGUAL IMMUNOTHERAPY AGAINST ALLERGY].

    Miyanaga, Noriaki / Takagi, Hideaki / Tono, Tetsuya / Sato, Katsuaki

    Arerugi = [Allergy

    2021  Volume 70, Issue 8, Page(s) 931–935

    MeSH term(s) Allergens ; Dendritic Cells ; Desensitization, Immunologic ; Humans ; Hypersensitivity/therapy ; Immunotherapy ; Sublingual Immunotherapy
    Chemical Substances Allergens
    Language Japanese
    Publishing date 2021-09-29
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    DOI 10.15036/arerugi.70.931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Dendritic cells and immunotherapy].

    Sato, Katsuaki

    Arerugi = [Allergy

    2014  Volume 63, Issue 7, Page(s) 914–919

    MeSH term(s) Animals ; Asthma/immunology ; Asthma/therapy ; Dendritic Cells/immunology ; Graft vs Host Disease/immunology ; Graft vs Host Disease/therapy ; Humans ; Immune System Diseases/immunology ; Immune System Diseases/therapy ; Immune Tolerance ; Immunosuppression ; Immunotherapy/methods ; Mice
    Language Japanese
    Publishing date 2014-07
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Selective Fabrication of Bismuthene and α-Bi on Hydrogen-Terminated SiC(0001).

    Yaegashi, Ken / Sugawara, Katsuaki / Kato, Takemi / Takahashi, Takashi / Sato, Takafumi

    Langmuir : the ACS journal of surfaces and colloids

    2022  Volume 38, Issue 44, Page(s) 13401–13406

    Abstract: Nanomaterials based on monoatomic bismuth (Bi) are attracting particular attention because they are candidates of two-dimensional (2D) topological insulators and Rashba metals useful for spintronic applications. We report convenient selective fabrication ...

    Abstract Nanomaterials based on monoatomic bismuth (Bi) are attracting particular attention because they are candidates of two-dimensional (2D) topological insulators and Rashba metals useful for spintronic applications. We report convenient selective fabrication of two different types of ultrathin Bi films, bismuthene and α-Bi on hydrogen-terminated SiC(0001), by combining the molecular-beam-epitaxy (MBE) method and the low-temperature and low-pressure hydrogen chemical etching of SiC. We have succeeded in selectively fabricating these two different Bi phases by simply tuning the substrate temperature during the MBE process. We observed that while bismuthene and α-Bi showed a similar low-energy electron diffraction pattern of the (√3 × √3)R30° periodicity, angle-resolved photoemission spectroscopy revealed a sizable difference in the band structure; bismuthene shows a massive Dirac cone, a signature of 2D topological insulators, whereas α-Bi exhibits an insulating behavior with a large band gap of more than 1.8 eV. We discuss the underlying mechanism of selective fabrication in terms of hydrogen desorption from the hydrogen-terminated SiC substrate.
    Language English
    Publishing date 2022-10-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c01678
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  5. Article ; Online: Mucosal color changes on narrow-band imaging in esophageal eosinophilic infiltration.

    Suda, Tsuyoshi / Shirota, Yukihiro / Hodo, Yuji / Sato, Katsuaki / Wakabayashi, Tokio

    Medicine

    2022  Volume 101, Issue 38, Page(s) e29891

    Abstract: This study aimed to examine the range of beige colored mucosa (BCM) in patients with esophageal eosinophilic infiltration (EEI) using narrow-band imaging (NBI). In this retrospective study, EEI was confirmed histologically in 12 consecutive patients from ...

    Abstract This study aimed to examine the range of beige colored mucosa (BCM) in patients with esophageal eosinophilic infiltration (EEI) using narrow-band imaging (NBI). In this retrospective study, EEI was confirmed histologically in 12 consecutive patients from January 2014 to December 2017. The BCM tone on NBI without magnifying endoscopy was evaluated, and red, green, and blue (RGB) values of BCM and normal mucosa were measured. BCM was macroscopically classified into 2 groups (bright and dark) using cluster analysis. Histopathological analysis was performed in 1 patient who underwent biopsy for both normal mucosa and BCM. All 12 patients presented with BCM. Endoscopy revealed fixed rings, longitudinal furrows, mucosal edema, and exudate in 3, 12, 10, and 8 patients, respectively. Strictures were absent. Five patients had findings suggestive of gastroesophageal reflux disease. In the cluster analysis, 5 and 7 patients had bright and dark BCM, respectively. Consistent results were noted when we categorized patients according to their macroscopic characteristics. RGB values of the BCM and normal mucosa were measured-normal mucosa: R: 99.8 ± 16.5, G: 121.7 ± 23.1, and B: 93.4 ± 19.2; BCM: R: 152.0 ± 31.3, G: 123.9 ± 35.0, and B: 97.5 ± 29.5. BCM had significantly higher R values than normal mucosa (P = .0001). All parameters were significantly lower in the dark BCM group than in the bright BCM group (P < .001). Histopathological analysis revealed expansion of the epithelial intercellular space, eosinophilic infiltration, and basal cell hyperplasia at the BCM sites. BCM was observed in all cases of EEI. RGB values differed between bright and dark BCM. Assessing BCM tone using NBI is a potentially novel diagnostic method for EEI.
    MeSH term(s) Endoscopy, Gastrointestinal ; Eosinophilia/pathology ; Esophagus/diagnostic imaging ; Esophagus/pathology ; Humans ; Mucous Membrane/diagnostic imaging ; Mucous Membrane/pathology ; Narrow Band Imaging/methods ; Retrospective Studies
    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000029891
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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells.

    Fukaya, Tomohiro / Uto, Tomofumi / Mitoma, Shuya / Takagi, Hideaki / Nishikawa, Yotaro / Tominaga, Moe / Choijookhuu, Narantsog / Hishikawa, Yoshitaka / Sato, Katsuaki

    Cell reports

    2023  Volume 42, Issue 5, Page(s) 112431

    Abstract: While dysbiosis in the gut is implicated in the impaired induction of oral tolerance generated in mesenteric lymph nodes (MesLNs), how dysbiosis affects this process remains unclear. Here, we describe that antibiotic-driven gut dysbiosis causes the ... ...

    Abstract While dysbiosis in the gut is implicated in the impaired induction of oral tolerance generated in mesenteric lymph nodes (MesLNs), how dysbiosis affects this process remains unclear. Here, we describe that antibiotic-driven gut dysbiosis causes the dysfunction of CD11c
    MeSH term(s) Humans ; Dysbiosis/metabolism ; Immunity, Innate ; Lymphocytes/metabolism ; Integrin alpha Chains/metabolism ; Dendritic Cells/metabolism ; Anti-Bacterial Agents/metabolism ; Intestinal Mucosa/metabolism
    Chemical Substances Integrin alpha Chains ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2023.112431
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  7. Article ; Online: Moiré-Assisted Realization of Octahedral MoTe

    Saruta, Yasuaki / Sugawara, Katsuaki / Oka, Hirofumi / Kawakami, Tappei / Kato, Takemi / Nakayama, Kosuke / Souma, Seigo / Takahashi, Takashi / Fukumura, Tomoteru / Sato, Takafumi

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 34, Page(s) e2304461

    Abstract: A current key challenge in 2D materials is the realization of emergent quantum phenomena in hetero structures via controlling the moiré potential created by the periodicity mismatch between adjacent layers, as highlighted by the discovery of ... ...

    Abstract A current key challenge in 2D materials is the realization of emergent quantum phenomena in hetero structures via controlling the moiré potential created by the periodicity mismatch between adjacent layers, as highlighted by the discovery of superconductivity in twisted bilayer graphene. Generally, the lattice structure of the original host material remains unchanged even after the moiré superlattice is formed. However, much less attention is paid for the possibility that the moiré potential can also modify the original crystal structure itself. Here, it is demonstrated that octahedral MoTe
    Language English
    Publishing date 2023-10-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202304461
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  8. Article ; Online: Clec4A4 Acts as a Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity.

    Uto, Tomofumi / Fukaya, Tomohiro / Mitoma, Shuya / Nishikawa, Yotaro / Tominaga, Moe / Choijookhuu, Narantsog / Hishikawa, Yoshitaka / Sato, Katsuaki

    Cancer immunology research

    2023  Volume 11, Issue 9, Page(s) 1266–1279

    Abstract: Clec4A4 is a C-type lectin receptor (CLR) exclusively expressed on murine conventional dendritic cells (cDC) to regulate their activation status. However, the functional role of murine Clec4A4 (mClec4A4) in antitumor immunity remains unclear. Here, we ... ...

    Abstract Clec4A4 is a C-type lectin receptor (CLR) exclusively expressed on murine conventional dendritic cells (cDC) to regulate their activation status. However, the functional role of murine Clec4A4 (mClec4A4) in antitumor immunity remains unclear. Here, we show that mClec4A4 serves as a negative immune checkpoint regulator to impair antitumor immune responses. Deficiency of mClec4A4 lead to a reduction in tumor development, accompanied by enhanced antitumor immune responses and amelioration of the immunosuppressive tumor microenvironment (TME) mediated through the enforced activation of cDCs in tumor-bearing mice. Furthermore, antagonistic mAb to human CLEC4A (hCLEC4A), which is the functional orthologue of mClec4A4, exerted protection against established tumors without any apparent signs of immune-related adverse events in hCLEC4A-transgenic mice. Thus, our findings highlight the critical role of mClec4A4 expressed on cDCs as a negative immune checkpoint molecule in the control of tumor progression and provide support for hCLEC4A as a potential target for immune checkpoint blockade in tumor immunotherapy.
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2732489-8
    ISSN 2326-6074 ; 2326-6066
    ISSN (online) 2326-6074
    ISSN 2326-6066
    DOI 10.1158/2326-6066.CIR-22-0536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Solitary extrahepatic hepatocellular carcinoma in vertebrae without a primary lesion in the liver might originate from bone marrow: a case report and new hypothesis based on a review of the literature and the latest findings.

    Shirota, Yukihiro / Ueda, Yoshimichi / Sato, Katsuaki / Takeda, Yasuhito / Hodo, Yuji / Wakabayashi, Tokio

    Clinical journal of gastroenterology

    2022  Volume 15, Issue 6, Page(s) 1115–1123

    Abstract: Solitary extrahepatic hepatocellular carcinoma without a primary lesion in the liver is rare and unique. In such patients, in addition to hepatocellular carcinoma, hepatoid adenocarcinoma, hepatoid teratoma, and hepatoid yolk sac tumor must be considered ...

    Abstract Solitary extrahepatic hepatocellular carcinoma without a primary lesion in the liver is rare and unique. In such patients, in addition to hepatocellular carcinoma, hepatoid adenocarcinoma, hepatoid teratoma, and hepatoid yolk sac tumor must be considered as differential diagnoses, and patients must be investigated in detail by histopathological studies with immunohistochemistry, especially using epithelial markers for which tumor cells are generally negative in hepatocellular carcinoma. A case with a solitary neoplasm of the vertebrae, which was diagnosed histopathologically as hepatocellular carcinoma, without a primary lesion is presented. The primary lesion was not identified even on autopsy, and the liver was pathologically almost normal. Given the review of the literature and circumstantial evidence, we would like to propose a bold new hypothesis that hepatocellular carcinoma might primarily originate from bone marrow.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; Bone Marrow/pathology ; Diagnosis, Differential ; Spine/pathology
    Language English
    Publishing date 2022-09-15
    Publishing country Japan
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2429411-1
    ISSN 1865-7265 ; 1865-7257
    ISSN (online) 1865-7265
    ISSN 1865-7257
    DOI 10.1007/s12328-022-01701-w
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  10. Article ; Online: Spatial gradients of geomagnetic temporal variations causing the instability of inter-station transfer functions

    Shinya Sato / Tada-nori Goto / Katsuaki Koike

    Earth, Planets and Space, Vol 72, Iss 1, Pp 1-

    2020  Volume 19

    Abstract: Abstract Spatial gradients in the primary geomagnetic fields directly contribute to both the amplitudes and phases of inter-station transfer functions (IS-TFs). This suggests that, for the analysis of subsurface resistivity structures, IS-TFs should be ... ...

    Abstract Abstract Spatial gradients in the primary geomagnetic fields directly contribute to both the amplitudes and phases of inter-station transfer functions (IS-TFs). This suggests that, for the analysis of subsurface resistivity structures, IS-TFs should be carefully treated by checking the establishment of the plane-wave assumption. Geomagnetic time-series data include various and complicated characteristics and accordingly, time–frequency domain analysis is suitable for the discussion of spatial gradients of time-varying geomagnetic fields. However, such evaluations are complicated by the huge amount of information contained in the spectrograms from several stations. Therefore, we propose a Multi-Channel Nonnegative Matrix Factorization (MC-NMF) method that can decompose raw spectrograms into several components, allowing the spatial gradient of each geomagnetic temporal variation to be identified. We confirm that such components actually affect the estimation of IS-TFs using data acquired at the Kakioka and Memambetsu magnetic observatories in Japan. We derive the year-to-year changes in IS-TFs from each set of paired stations among Kakioka, Kanoya, and Memambetsu observatories. Although the IS-TFs should exhibit opposite polarities (a negative correlation) when the input and output observatories are swapped; surprisingly, some of them have “identical” polarities. The application of MC-NMF shows that the analyzed geomagnetic data include several components that have various spatial gradients. Although IS-TFs sometimes fail to give the expected implication regarding the spatial gradients of geomagnetic temporal variations, MC-NMF can verify whether the IS-TFs exhibit any spatial gradients. Thus, the use of IS-TFs with MC-NMF can yield better implications regarding subsurface resistivity information.
    Keywords Inter-station transfer functions ; Nonnegative matrix factorization ; Spatial gradients ; Geomagnetic temporal variations ; Geography. Anthropology. Recreation ; G ; Geodesy ; QB275-343 ; Geology ; QE1-996.5
    Subject code 550
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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