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  1. Article ; Online: Severity and Cardiac Involvement in Multisystem Inflammatory Syndrome in Children: Authors' Reply.

    Raghunathan, Veena / Dhaliwal, Maninder / Singhi, Sunit

    Indian journal of pediatrics

    2023  Volume 90, Issue 4, Page(s) 424

    MeSH term(s) Child ; Humans ; Connective Tissue Diseases ; Systemic Inflammatory Response Syndrome/diagnosis
    Language English
    Publishing date 2023-02-09
    Publishing country India
    Document type Letter ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04455-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Severe Dengue: Developing a Universally Applicable Simple Prediction Model.

    Singhi, Sunit C

    Indian journal of pediatrics

    2018  Volume 85, Issue 6, Page(s) 413–414

    MeSH term(s) Dengue ; Dengue Virus ; Humans
    Language English
    Publishing date 2018
    Publishing country India
    Document type Editorial ; Review ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-018-2668-2
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  3. Article ; Online: Scrub Typhus Associated with Guillain-Barré Syndrome (GBS).

    Raghunathan, Veena / Dhaliwal, Maninder / Singhi, Pratibha / Singhi, Sunit

    Indian journal of pediatrics

    2022  Volume 89, Issue 11, Page(s) 1129–1130

    Abstract: Scrub typhus is a vector-borne disease caused by Orientia tsutsugamushi. Clinical manifestations generally occur due to vasculitis and inflammation and can have variable degrees of systemic involvement. Meningoencephalitis and cerebellitis are well-known ...

    Abstract Scrub typhus is a vector-borne disease caused by Orientia tsutsugamushi. Clinical manifestations generally occur due to vasculitis and inflammation and can have variable degrees of systemic involvement. Meningoencephalitis and cerebellitis are well-known neurological manifestations of scrub typhus, but the occurrence of Guillain-Barré syndrome is extremely rare. The authors report a 7-y-old boy who developed fever followed by rapidly progressive ascending quadriparesis with areflexia and whose etiological workup revealed positive IgM scrub typhus antibody, as well as, a high OXK titer (1:80). Nerve-conduction studies in all four limbs were suggestive of demyelinating neuropathy. He showed complete recovery after treatment with intravenous immunoglobulin (2 g/kg) and azithromycin.
    MeSH term(s) Azithromycin/therapeutic use ; Guillain-Barre Syndrome/complications ; Guillain-Barre Syndrome/diagnosis ; Humans ; Immunoglobulin M ; Immunoglobulins, Intravenous/therapeutic use ; Male ; Orientia tsutsugamushi ; Scrub Typhus/complications ; Scrub Typhus/diagnosis ; Scrub Typhus/drug therapy
    Chemical Substances Immunoglobulin M ; Immunoglobulins, Intravenous ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2022-07-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04312-y
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  4. Article ; Online: Kawasaki Disease with Adenoviral Infection.

    Khanna, Pooja / Parihar, Arjun / Gupta, Aditi / Yadav, Saurav / Singhi, Sunit Chandra

    Indian journal of pediatrics

    2023  

    Language English
    Publishing date 2023-12-21
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04995-x
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  5. Article ; Online: Miller Fisher Syndrome Associated With COVID-19 Infection.

    Raghunathan, Veena / Dhaliwal, Maninder / Singhi, Pratibha / Singhi, Sunit

    Pediatric neurology

    2021  Volume 123, Page(s) 40

    MeSH term(s) COVID-19 ; Humans ; Miller Fisher Syndrome/complications ; Miller Fisher Syndrome/diagnosis ; SARS-CoV-2
    Language English
    Publishing date 2021-07-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2021.07.002
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  6. Article ; Online: Cidofovir in Severe Hypoxemic Adenoviral Pneumonia.

    Gupta, Aditi / Khanna, Pooja / Parihar, Arjun / Singh, Dhirendra Pratap / Singhi, Sunit Chandra

    Indian journal of pediatrics

    2023  Volume 91, Issue 4, Page(s) 398–400

    Abstract: The authors present a 16-mo-old boy with flu like symptoms, not responding to supportive management and progressed to severe hypoxemic pneumonia. Adenovirus was detected in the nasopharyngeal aspirate. He showed rapid improvement after intravenous ... ...

    Abstract The authors present a 16-mo-old boy with flu like symptoms, not responding to supportive management and progressed to severe hypoxemic pneumonia. Adenovirus was detected in the nasopharyngeal aspirate. He showed rapid improvement after intravenous cidofovir administration.
    MeSH term(s) Male ; Humans ; Cidofovir/therapeutic use ; Antiviral Agents/therapeutic use ; Organophosphonates/therapeutic use ; Cytosine/therapeutic use ; Adenoviridae Infections/diagnosis ; Pneumonia, Viral
    Chemical Substances Cidofovir (JIL713Q00N) ; Antiviral Agents ; Organophosphonates ; Cytosine (8J337D1HZY)
    Language English
    Publishing date 2023-08-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04812-5
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  7. Article ; Online: Safety and Outcomes of Midline and Peripherally Inserted Central Catheters in a Pediatric Intensive Care Unit.

    Raghunathan, Veena / Dhaliwal, Maninder / Singh, Dhirendra Pratap / Singh, Gargi / Singhi, Sunit

    Indian pediatrics

    2023  Volume 60, Issue 9, Page(s) 731–735

    Abstract: Objectives: We describe our experience with use of midline catheters in PICU and compare the performance of midline catheters to peripherally inserted central catheters (PICC).: Methods: A review of hospital records was done to including all ... ...

    Abstract Objectives: We describe our experience with use of midline catheters in PICU and compare the performance of midline catheters to peripherally inserted central catheters (PICC).
    Methods: A review of hospital records was done to including all pediatric patients admitted in the pediatric intensive care unit of a tertiary care centre who underwent placement of midline catheters or PICC, over a period of 18 months (July, 2019 to January, 2021). Patient details, indication, type of catheter and number of attempts at insertion, type and number of infusions administered, dwell time and complications were retrieved from the records. Comparison was made between the midline and PICC groups.
    Results: The median (IQR) age of children was 7 (3-12) years (75.5% males). 161 midline catheters and 104 PICC were inserted with first attempt success rates of 87.6% and 78.8%, respectively. Median cubital vein was used for majority of the insertions (52.8%). Common complications with midline catheters were pain (n=9, 5.6%), blockage (n=8, 5%) and thrombophlebitis (n=6, 3.7%). Median (interquartile range) dwell time in midline group was 7 (5-10) days. The duration of backflow and dwell time were higher in the PICC group compared to midline group (5.5 vs 3 days; P<0.001 and 9 vs 7 days; P<0.001, respectively).
    Conclusion: Retrospective data showed that midline catheters had good utility in PICU, especially in moderately sick children (PRISM score up to 12), and provide a secure intravenous access, which can last for a week.
    MeSH term(s) Male ; Humans ; Child ; Female ; Catheterization, Central Venous/adverse effects ; Retrospective Studies ; Central Venous Catheters/adverse effects ; Intensive Care Units, Pediatric ; Catheters ; Pain ; Catheterization, Peripheral/adverse effects ; Catheter-Related Infections
    Language English
    Publishing date 2023-05-19
    Publishing country India
    Document type Review ; Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
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  8. Article: Enigma of low-serum zinc, selenium, and prolactin with lymphopenia.

    Singhi, Sunit

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2013  Volume 14, Issue 4, Page(s) 443–445

    MeSH term(s) Critical Illness ; Female ; Humans ; Male ; Prolactin/blood ; Selenium/blood ; Zinc/blood
    Chemical Substances Prolactin (9002-62-4) ; Selenium (H6241UJ22B) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0b013e3182760687
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  9. Article: The authors reply.

    Ramaswamy, Karthik N / Singhi, Sunit C

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2017  Volume 18, Issue 2, Page(s) 203–204

    Language English
    Publishing date 2017-02-03
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000001042
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  10. Article ; Online: Principles of Management of Central Nervous System Infections.

    Singhi, Sunit / Angurana, Suresh Kumar

    Indian journal of pediatrics

    2018  Volume 86, Issue 1, Page(s) 52–59

    Abstract: CNS infections in children are medical emergency and are associated with high mortality and morbidity. For diagnosis, a high index of suspicion is required. Clinical assessment should be supplemented by laboratory investigations including CSF Gram stain ... ...

    Abstract CNS infections in children are medical emergency and are associated with high mortality and morbidity. For diagnosis, a high index of suspicion is required. Clinical assessment should be supplemented by laboratory investigations including CSF Gram stain and cultures, blood culture, PCR on CSF, serological tests, and imaging. Commonly associated life threatening complications include coma, seizure, raised intracranial pressure (ICP), focal deficits, shock, respiratory failure, and fluid and electrolyte abnormalities. Immediate management should first address control of airway, breathing and circulation; protocolized management of raised ICP and status epilepticus; maintaining adequate intravascular volume; and close monitoring for early detection of complications. Appropriate antimicrobial agents should be administered promptly according to the suspected pathogen. Clinical evaluation, laboratory workup, specific antimicrobial therapy, supportive treatment, and management of associated complications should go hand in hand in a protocolized way for better outcome.
    MeSH term(s) Anti-Infective Agents/therapeutic use ; Anticonvulsants/therapeutic use ; Central Nervous System Infections/diagnosis ; Central Nervous System Infections/therapy ; Chemoprevention ; Child ; Electroencephalography ; Fluid Therapy ; Glucocorticoids/therapeutic use ; Glycerol/therapeutic use ; Hematologic Tests ; Humans ; Incidence ; Intracranial Hypertension/prevention & control ; Neuroimaging ; Respiration, Artificial ; Seizures/drug therapy ; Seizures/etiology ; Spinal Puncture ; Vaccination
    Chemical Substances Anti-Infective Agents ; Anticonvulsants ; Glucocorticoids ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2018-01-15
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-017-2583-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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