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Article ; Online: Machine learning-based soil quality assessment for enhancing environmental monitoring in iron ore mining-impacted ecosystems.

Lima, Helena Santiago / Oliveira, Gustavo Ferreira Viegas de / Ferreira, Ricardo Dos Santos / Castro, Alex Gazolla de / Silva, Lívia Carneiro Fidélis / Ferreira, Letícia de Souza / Oliveira, Diego Aniceto Dos Santos / Silva, Leonardo Ferreira da / Kasuya, Maria Catarina Megumi / de Paula, Sérgio Oliveira / Silva, Cynthia Canêdo da

Journal of environmental management

2024 Volume 356, Page(s) 120559

Abstract: In November 2015, a catastrophic rupture of the Fundão dam in Mariana (Brazil), resulted in extensive socio-economic and environmental repercussions that persist to this day. In response, several reforestation programs were initiated to remediate the ... ...

Abstract	In November 2015, a catastrophic rupture of the Fundão dam in Mariana (Brazil), resulted in extensive socio-economic and environmental repercussions that persist to this day. In response, several reforestation programs were initiated to remediate the impacted regions. However, accurately assessing soil health in these areas is a complex endeavor. This study employs machine learning techniques to predict soil quality indicators that effectively differentiate between the stages of recovery in these areas. For this, a comprehensive set of soil parameters, encompassing 3 biological, 16 chemical, and 3 physical parameters, were evaluated for samples exposed to mining tailings and those unaffected, totaling 81 and 6 samples, respectively, which were evaluated over 2 years. The most robust model was the decision tree with a restriction of fewer levels to simplify the tree structure. In this model, Cation Exchange Capacity (CEC), Microbial Biomass Carbon (MBC), Base Saturation (BS), and Effective Cation Exchange Capacity (eCEC) emerged as the most pivotal factors influencing model fitting. This model achieved an accuracy score of 92% during training and 93% during testing for determining stages of recovery. The model developed in this study has the potential to revolutionize the monitoring efforts conducted by regulatory agencies in these regions. By reducing the number of parameters that necessitate evaluation, this enhanced efficiency promises to expedite recovery monitoring, simultaneously enhancing cost-effectiveness while upholding the analytical rigor of assessments.
MeSH term(s)	Ecosystem ; Soil/chemistry ; Iron Compounds ; Environmental Monitoring ; Mining ; Brazil ; Iron/analysis ; Cations ; Rivers/chemistry
Chemical Substances	Soil ; Iron Compounds ; Iron (E1UOL152H7) ; Cations
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2024.120559
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Article ; Online: In-water resuscitation during a surf rescue: Time lost or breaths gained? A pilot study.

Barcala-Furelos, Roberto / de Oliveira, Joel / Duro-Pichel, Paula / Colón-Leira, Sergio / Sanmartín-Montes, Marcos / Aranda-García, Silvia

The American journal of emergency medicine

2024 Volume 79, Page(s) 48–51

Abstract: Background: A technique called in-water resuscitation (IWR) was devised on a surfboard to ventilate persons who seemingly did not breathe upon a water rescue. Despite IWR still raises uncertainties regarding its applicability, this technique is ... ...

Abstract	Background: A technique called in-water resuscitation (IWR) was devised on a surfboard to ventilate persons who seemingly did not breathe upon a water rescue. Despite IWR still raises uncertainties regarding its applicability, this technique is recommended by the International Liaison Committee for Resuscitation (ILCOR). Thus, this study aimed to evaluate the feasibility of IWR with a rescue board before and during towing and, to compare rescue times and rescue-associated fatigue levels between rescues with rescue breath attempts and without (SR). Methods: A randomized crossover pilot test was conducted: 1) IWR test with pocket mask and, 2) Conventional SR test. IWR tests were conducted using a Laerdal ResusciAnne manikin (Stavanger, Norway). Three groups of variables were recorded: a) rescue time (in s), b) effective ventilations during rescue, and c) rating of perceived effort (RPE). Results: Focusing on the rescue time, the performance SR was significantly faster than IWR rescue which took 61 s longer to complete the rescue (Z = -2.805; p = 0.005). No significant differences were found between techniques for the RPE (T = -1.890; p = 0.095). In the IWR analysis, lifeguards performed an average of 27 ± 12 rescue breaths. Conclusion: The application of IWR on a rescue board is feasible both at the time of rescue and during towing. It shortens the reoxygenation time but delays the arrival time to shore. Both IWR and SR result in similar levels of perceived fatigue.
MeSH term(s)	Humans ; Cardiopulmonary Resuscitation/methods ; Fatigue/therapy ; Near Drowning/therapy ; Pilot Projects ; Water ; Cross-Over Studies
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2024-02-07
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	605890-5
ISSN	1532-8171 ; 0735-6757
ISSN (online)	1532-8171
ISSN	0735-6757
DOI	10.1016/j.ajem.2024.02.010
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Article ; Online: Sex- and estrous-related response patterns for alcohol depend critically on the level of compulsion-like challenge.

De Oliveira Sergio, Thatiane / Darevsky, David / Kellner, Jacob / de Paula Soares, Vanessa / de Cassia Albino, Maryelle / Maulucci, Danielle / Wean, Sarah / Hopf, Frederic W

Progress in neuro-psychopharmacology & biological psychiatry

2024 Volume 133, Page(s) 111008

Abstract: Alcohol use disorder is a substantial social and economic burden. During the last years, the number of women with drinking problems has been increasing, and one main concern is that they are particularly more vulnerable to negative consequences of ... ...

Abstract	Alcohol use disorder is a substantial social and economic burden. During the last years, the number of women with drinking problems has been increasing, and one main concern is that they are particularly more vulnerable to negative consequences of alcohol. However, little is known about female-specific response patterns for alcohol, and potential underlying differences in brain mechanisms, including for compulsion-like alcohol drinking (when intake persists despite adverse consequences). We used lickometry to assess behavioral microstructure in adult Wistar male and female rats (n = 28-30) during alcohol-only drinking or moderate- or higher-challenge alcohol compulsion (10 or 60 mg/l quinine in alcohol, respectively). Estrous stages were determined and related to drinking levels and patterns of responding to alcohol, as was ovariectomy. Our findings showed that females (where we didn't determine estrus stage) had similar total licks in a session as males, but significantly longer licking bouts under alcohol-only and moderate-challenge, suggesting greater persistence. Further, greater intake under alcohol-only and moderate-challenge was related to faster licking in males, while female consumption was not related to licking speed. Thus, females could have increased persistence without greater vigor, unlike males. However, under higher-challenge, faster licking did predict higher intake in females, similar to males. To better understand female higher-challenge responding, we examined drinking in relation to phases of the estrous cycle. Higher-challenge had longer bouts only in late diestrus. In addition, ovariectomy led to longer bouts only under higher-challenge, suggesting that conditions with reduced hormone levels could increase female persistence for alcohol under higher-challenge. However, ovariectomy also reduced alcohol-only and moderate-challenge drinking but did not reduce bout length. Thus, intake level and response strategy could be regulated somewhat differently by ovarian hormones. Finally, moderate-challenge licking speed was less variable during early diestrus, and we previously showed more stereotyped responding specifically under moderate-challenge in males. By combining behavioral microstructure and sex- and estrus-related changes in drinking patterns, our results suggest that females have greater persistence for alcohol under lower-challenge drinking, while late diestrus and ovariectomy unmasked greater persistence under higher-challenge. Together, our novel insights could help develop more effective and personalized treatments for problematic alcohol use.
Language	English
Publishing date	2024-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	781181-0
ISSN	1878-4216 ; 0278-5846
ISSN (online)	1878-4216
ISSN	0278-5846
DOI	10.1016/j.pnpbp.2024.111008
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Article ; Online: Exploring the antifungal potential of Annona muricata leaf extract-loaded hydrogel in treating vulvovaginal candidiasis.

Campos, Lara Melo / de Oliveira Lemos, Ari Sérgio / de Lima Paula, Priscila / da Rocha, Vinícius Novaes / de Freitas Araújo, Marcelo Gonzaga / Tavares, Guilherme Diniz / Barradas, Thais Nogueira / Nascimento, Wesley William Gonçalves / Denadai, Angelo Mácio Leite / de Oliveira, Luiz Fernando Cappa / Fabri, Rodrigo Luiz

Colloids and surfaces. B, Biointerfaces

2024 Volume 238, Page(s) 113919

Abstract: Vulvovaginal candidiasis, mostly caused by Candida albicans, remains a prevalent concern in women's health. Annona muricata L. (Annonaceae), a plant native from Brazil, is well-known for its therapeutic potential, including antitumor, anti-inflammatory, ... ...

Abstract	Vulvovaginal candidiasis, mostly caused by Candida albicans, remains a prevalent concern in women's health. Annona muricata L. (Annonaceae), a plant native from Brazil, is well-known for its therapeutic potential, including antitumor, anti-inflammatory, and antimicrobial properties. This study presents an innovative hydrogel formulation containing the ethanolic extract from A. muricata leaves designed to control C. albicans in an in vivo model of vulvovaginal candidiasis. Here, we report the development, thermal, physicochemical and rheological characterization of a Carbopol®-based hydrogel containing A. muricata extract. Furthermore, we evaluated its activity in a vulvovaginal candidiasis in vivo model. Thermal analyses indicated that the addition of the extract increased the polymer-polymer and polymer-solvent interactions.Rheological analysis showed a decrease in the viscosity and elasticity of the formulation as the A. muricata extract concentration increased, suggesting a liquid-like behavior. After treatment with the Carbopol®-based hydrogel with A. muricata, our in vivo results showed a significant reduction in vulvovaginal fungal burden and infection, as well as a reduction in mucosal inflammation. The current research opens up possibilities for the application of the Carbopol®-based hydrogel with A. muricata as a natural therapeutic option for the treatment of vulvovaginal candidiasis.
Language	English
Publishing date	2024-04-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1500523-9
ISSN	1873-4367 ; 0927-7765
ISSN (online)	1873-4367
ISSN	0927-7765
DOI	10.1016/j.colsurfb.2024.113919
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Article ; Online: Aedes aegypti

de Oliveira, Joice Guilherme / Netto, Sérgio Antônio / Francisco, Edenilson Osinski / Vieira, Caroline Pereira / Variza, Paula Fassicolo / Iser, Betine Pinto Moehlecke / Lima-Camara, Tamara Nunes / Lorenz, Camila / Prophiro, Josiane Somariva

Tropical medicine and infectious disease

2023 Volume 8, Issue 2

Abstract: In Brazil, the ... ...

Abstract	In Brazil, the mosquito
Language	English
Publishing date	2023-01-20
Publishing country	Switzerland
Document type	Journal Article
ISSN	2414-6366
ISSN (online)	2414-6366
DOI	10.3390/tropicalmed8020077
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Article ; Online: Nutritional profile and outcomes of noncritical hospitalized patients with COVID-19 in a large tertiary hospital in southern Brazil.

Nunes, Emeline Caldana / Marcon, Sabrina / Oliveira, Paula Elisa de / Loss, Sergio Henrique

Revista da Associacao Medica Brasileira (1992)

2022 Volume 68, Issue 9, Page(s) 1216–1220

Abstract: Introduction: Patients with chronic diseases, such as diabetes and cardiovascular diseases, and old age, which are associated with a high risk of malnutrition and worse outcomes, are at a higher risk for developing the severe presentation of COVID-19.!## ...

Abstract	Introduction: Patients with chronic diseases, such as diabetes and cardiovascular diseases, and old age, which are associated with a high risk of malnutrition and worse outcomes, are at a higher risk for developing the severe presentation of COVID-19. Methods: This is an observational and cross-sectional study with a sample defined by convenience. Data were collected in adult inpatient units through information obtained via telephone contact with the patient/companion, records collected by the nursing staff, and medical records, tabulating demographics, body composition, previous illnesses, nutritional diagnoses, diet acceptance, and hospitalization outcomes. The following symptoms were observed: inappetence, smell, dysgeusia, odynophagia, nausea, vomiting, and diarrhea. Results: Most deaths occurred after transfer to the intensive care unit (79.6%). Patients with the worst outcome had lower food intake with a cutoff point of 60% for diet acceptance, which seems to be an adequate discriminator between those who survived and those who did not. Gastrointestinal symptoms were significantly associated with food consumption below 60% of the planned goal. The symptoms most associated with lower energy intake were inappetence, dysgeusia, and nausea/vomiting. Conclusions: Reduced caloric intake and the presence of nutritional risk or its appearance during hospitalization seemed to be associated with mortality in patients with COVID-19 admitted outside the intensive care unit.
MeSH term(s)	Adult ; Brazil/epidemiology ; COVID-19 ; Cross-Sectional Studies ; Dysgeusia ; Hospitalization ; Humans ; Nausea ; Tertiary Care Centers ; Vomiting
Language	English
Publishing date	2022-10-19
Publishing country	Brazil
Document type	Journal Article ; Observational Study
ZDB-ID	731969-1
ISSN	1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
ISSN (online)	1806-9282
ISSN	0104-4230 ; 0004-5241 ; 0102-843X
DOI	10.1590/1806-9282.20220240
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Article: Efficacy of Preemptive Analgesia with Amantadine for Controlling Postoperative Pain in Cats Undergoing Ovariohysterectomy.

Guedes, Paula Elisa Brandão / Pinto, Taísa Miranda / Corrêa, Janaína Maria Xavier / Niella, Raquel Vieira / Dos Anjos, Carolina Moreira / de Oliveira, Jéssica Natália Silva / Marques, Claire Souza da Costa / de Souza, Sophia Saraiva / da Silva, Elisângela Barboza / de Lavor, Mário Sérgio Lima

Animals : an open access journal from MDPI

2024 Volume 14, Issue 4

Abstract: This study aimed to evaluate the effect of the preemptive administration of amantadine on postoperative analgesia in cats undergoing ovariohysterectomy and its influence on the physiological parameters. Twenty healthy domestic cats scheduled to undergo ... ...

Abstract	This study aimed to evaluate the effect of the preemptive administration of amantadine on postoperative analgesia in cats undergoing ovariohysterectomy and its influence on the physiological parameters. Twenty healthy domestic cats scheduled to undergo ovariohysterectomy at the Santa Cruz State University, Ilhéus, were divided into two groups: the control group (Group C;
Language	English
Publishing date	2024-02-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani14040643
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Article ; Online: Superficial Femoral Artery in-Stent Restenosis Treated with Paclitaxel-Coated Balloon Angioplasty - Results of Three-Year Follow-Up.

Peclat de Oliveira, Julio Cesar / Alvim Fiorelli, Rossano Kepler / Rolim Maia Peclat, Ana Paula / Peclat de Oliveira, Lucas Maia / Oliveira, Rafael / Belczac, Sergio Quilici / Almeida, Renato Santos / Dalio, Marcelo Bellini / Joviliano, Edwaldo Edner / Gutfilen, Bianca

Vascular and endovascular surgery

2023 Volume 57, Issue 7, Page(s) 673–679

Abstract: Background: In-stent restenosis remains a common and important complication after endovascular treatment of superficial femoral artery peripheral artery disease. It occurs in 14 to 35% of cases in 1 year and there is still no efficient treatment for ... ...

Abstract	Background: In-stent restenosis remains a common and important complication after endovascular treatment of superficial femoral artery peripheral artery disease. It occurs in 14 to 35% of cases in 1 year and there is still no efficient treatment for this condition. Paclitaxel-coated balloons have shown promising results. Objective: Investigate the 3 year results of superficial femoral artery in-stent restenosis treated with paclitaxel-coated balloon angioplasty, using the Lutonix™ 035 device. Methods: We conducted a retrospective observational study with patients with symptomatic (Rutherford 2 to 5) superficial femoral artery in-stent restenosis, that were treated with paclitaxel-coated balloon angioplasty using the Lutonix™ 035 device, in a single center from January 2016 to December 2020. Duplex scan was used to follow the patients. Primary patency was obtained through Kaplan-Meier analysis. Mortality, and amputation rates were also evaluated. Results: 105 patients were included. Two patients had technical failure and required an additional stent, and were thus excluded. 103 patients were analyzed. Primary patency was 91.26, 80.47, and 67.71%, respectively, in the first, second, and third year after the procedure. There were no deaths 30 days after the procedure. There were no major amputations during the 3 year follow-up. Conclusion: Paclitaxel-coated balloon angioplasty with the Lutonix™ 035 device was a safe and effective treatment to superficial femoral artery in-stent restenoses. The results were maintained along the 3 year follow-up.
MeSH term(s)	Humans ; Femoral Artery/diagnostic imaging ; Treatment Outcome ; Follow-Up Studies ; Paclitaxel/adverse effects ; Coronary Restenosis ; Vascular Patency ; Angioplasty, Balloon ; Peripheral Arterial Disease/diagnostic imaging ; Peripheral Arterial Disease/therapy ; Constriction, Pathologic ; Coated Materials, Biocompatible ; Popliteal Artery
Chemical Substances	Paclitaxel (P88XT4IS4D) ; Coated Materials, Biocompatible
Language	English
Publishing date	2023-03-22
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	2076272-0
ISSN	1938-9116 ; 1538-5744
ISSN (online)	1938-9116
ISSN	1538-5744
DOI	10.1177/15385744231165877
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Article: Isolation and Characterization of the

da Silva, Jéssica Duarte / Bens, Lene / Santos, Adriele J do Carmo / Lavigne, Rob / Soares, José / Melo, Luís D R / Vallino, Marta / Dias, Roberto Sousa / Drulis-Kawa, Zuzanna / de Paula, Sérgio Oliveira / Wagemans, Jeroen

Microorganisms

2023 Volume 11, Issue 9

Abstract: ... Proteus ... ...

Abstract	Proteus mirabilis
Language	English
Publishing date	2023-08-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11092141
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Article ; Online: Melipona stingless bees and honey microbiota reveal the diversity, composition, and modes of symbionts transmission.

Cerqueira, Alan Emanuel Silva / Lima, Helena Santiago / Silva, Lívia Carneiro Fidélis / Veloso, Tomás Gomes Reis / de Paula, Sérgio Oliveira / Santana, Weyder Cristiano / da Silva, Cynthia Canêdo

FEMS microbiology ecology

2024

Abstract: The Melipona gut microbes differ from other social bees, with the absence of crucial corbiculate core gut symbionts and the high occurrence of environmental strains. We studied the microbial diversity and composition of three Melipona species and their ... ...

Abstract	The Melipona gut microbes differ from other social bees, with the absence of crucial corbiculate core gut symbionts and the high occurrence of environmental strains. We studied the microbial diversity and composition of three Melipona species and their honey to understand which strains are obtained by horizontal transmission (HT) from the pollination environment; or represent symbionts co-evolved with Melipona by HT from the hive/food stores or vertical transmission (VT) via social interactions. Bees harbored higher microbial alpha diversity and a different and more species-specific bacterial composition than honey. Otherwise, the fungal communities of bee and honey samples are less dissimilar. As expected, the core symbionts Snodgrassella and Gilliamella were absent in bees that had a prevalence of Lactobacillus Firm-5, environmental Lactobacillaceae, Bifidobacteriaceae and Acetobacteraceae. Also, Pectinatus and Floricoccus have habitat preferences for bees, putatively representing novel symbionts from the environment that co-evolved via VT among generations. Fructilactobacillus found in bees possibly had HT to bees from honey stores. Metschnikowia yeasts, consistent in all bees and honey samples, might have HT to bees from food stores. Similarly, Saccharomycetales might have HT from honey or plants/flowers to bees. This work contributes to the understanding of Melipona symbionts and their modes of transmission.
Language	English
Publishing date	2024-04-22
Publishing country	England
Document type	Journal Article
ZDB-ID	283722-5
ISSN	1574-6941 ; 0168-6496
ISSN (online)	1574-6941
ISSN	0168-6496
DOI	10.1093/femsec/fiae063
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